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^(18)F-FDG PET/CT对早期活动性大动脉炎的诊断价值分析

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中华解剖与临床杂志 2024年第1期29卷 24-28页

作者：刘翔尚宇刘军梁宇霞高俊刚段小艺牛晨西安交通大学第一附属医院PET/CT室西安710061

目的探讨^(18)F-脱氧葡萄糖(^(18)F-FDG)正电子发射体层摄影(PET)/CT对早期活动性大动脉炎(TA)患者的诊断价值。方法病例对照研究。纳入西安交通大学第一附属医院2020年1月—2022年12月行PET/CT检查的10例早期活动性TA患者的临床资料,... 详细信息

目的探讨^(18)F-脱氧葡萄糖(^(18)F-FDG)正电子发射体层摄影(PET)/CT对早期活动性大动脉炎(TA)患者的诊断价值。方法病例对照研究。纳入西安交通大学第一附属医院2020年1月—2022年12月行PET/CT检查的10例早期活动性TA患者的临床资料,其中男2例、女8例,年龄20~72(44.9±17.7)岁,为TA组;选择同期年龄、性别匹配的10例非TA的受检者作为对照组,均行^(18)F-FDG PET/CT显像检查。观察研究对象的显像结果,由2位有经验的影像科医师分别勾画血管病变,测量TA组病变段血管壁与对照组主动脉段血管壁对^(18)F-FDG的最大标准摄取值(SUVmax),比较2组SUVmax的差异。采用Spearman相关性分析方法,探讨TA组病变动脉段血管壁局部对^(18)F-FDG的SUVmax值与红细胞沉降率(ESR)、C反应蛋白(CRP)的关系。结果10例早期活动性TA患者^(18)F-FDG PET/CT显像中均可看到主动脉及其主要分支血管壁葡萄糖代谢轻至中度增高。TA组的^(18)F-FDG SUVmax值为3.38±0.85,明显高于对照组的1.68±0.24,差异有统计学意义(t=6.12,P<0.001)。TA组的^(18)F-FDG SUVmax值与ESR无相关性(r_(s)=0.489,P=0.151),与CRP呈正相关(r_(s)=0.758,P=0.011),ESR与CRP间无相关性(r_(s)=0.479,P=0.162)。结论^(18)F-FDG PET/CT可准确显示TA的病变范围,并通过血管壁的SUVmax反映TA的活动性,是诊断早期活动性TA的一种可靠的影像学手段。

关键词：大动脉炎早期诊断正电子发射体层摄影/计算机体层成像 ^(18)F-脱氧葡萄糖红细胞沉降率 C反应蛋白

Three-dimensional (3D) structure model and its parameters for poplar shelterbelts

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Science China Earth Sciences 2010年第10期53卷 1513-1526页

作者： FAN ZhiPing gao jungang ZENG DeHui ZHOU XinHua SUN XueKai Daqinggou Ecological Station Institute of Applied EcologyChinese Academy of SciencesShenyang 110016China Graduate University of Chinese Academy of Sciences Beijing 100049China School of Natural Resources University of NebraskaLincolnNE 68583-0995USA

The spatial functions of surface area density(vegetative surface area per unit canopy volume) and cubic density(vegetative volume per unit canopy volume) have been used as two three-dimensional(3D) structural descriptors for *** functions were defined by models as a general ***,sub-models such as surface area,volume,and corresponding distributions were not explicitly defined for poplar trees,which are a dominant woody species in shelterbelts all over China,and this limits applications of the models in China and *** order to define and develop these sub-models for shelterbelts,poplar trees were destructively sampled from multiple-row shelterbelts and then were measured for their surface area and *** these measurements,we estimated parameters to define their equations *** on the architecture and planting patterns of trees in shelterbelts,the distribution of the surface areas and volumes vertically and across the width for different tree heights were constructed for the three components of trunks,branches and *** the defined equations into the models,we described the 3D structure of a multiple-row poplar *** results showed that,the spatial change in magnitude of surface area density(0.215-10.131 m2/m3) or cubic density(0.00007-0.04667 m3/m3) in shelterbelts is large and their distributions are not *** assumption for boundary-layer flow modeling efforts that the 3D distribution of shelterbelt structure was uniform is not the case in *** 3D structure model not only can be used to model the flow field as influenced by each tree component,but also can express the entire aerodynamic characteristics of a *** methodologies and equations that are developed in this study can be applied to estimate the 3D structure of a shelterbelt with a design similar to our studied poplar shelterbelts in terms of species composition and planting *** fitted models can be used to

关键词： aerodynamics cubic density porosity numerical simulation surface area density

^(18)F-PSMA-1007 PET/CT与^(18)F-FDG PET/CT在脑胶质瘤分级评估中的对比研究

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中华解剖与临床杂志 2024年第1期29卷 9-14页

作者：尚宇刘军李瑞春梁华高俊刚刘翔周明静齐思言牛晨西安交通大学第一附属医院PET/CT室西安710061

目的对比^(18)F-前列腺特异性膜抗原(^(18)F-PSMA)-1007正电子发射体层摄影(PET)/CT与^(18)F-脱氧葡萄糖(^(18)F-FDG)PET/CT在脑胶质瘤分级诊断中的应用价值。方法回顾性队列研究。纳入2022年8月—2023年3月西安交通大学第一附属医院脑... 详细信息

目的对比^(18)F-前列腺特异性膜抗原(^(18)F-PSMA)-1007正电子发射体层摄影(PET)/CT与^(18)F-脱氧葡萄糖(^(18)F-FDG)PET/CT在脑胶质瘤分级诊断中的应用价值。方法回顾性队列研究。纳入2022年8月—2023年3月西安交通大学第一附属医院脑胶质瘤患者32例,其中男16例、女16例,年龄19~79(50.3±13.2)岁。患者术前均行头颅^(18)F-PSMA-1007 PET/CT和^(18)F-FDG PET/CT检查,2次扫描间隔时间均<1周;均接受颅内占位切除术治疗,术后病理WHO分级Ⅱ级14例、Ⅲ6例、Ⅳ级12例。根据WHO分级将患者分为2组:Ⅲ~Ⅳ级18例为高级别胶质瘤(HGG)组,Ⅱ级14例为低级别胶质瘤(LGG)组。观察指标:(1)比较HGG组和LGG组在^(18)F-PSMA-1007 PET/CT和^(18)F-FDG PET/CT图像中病灶最大标准摄取值(SUVmax)、肿瘤/背景比值(TBR)的差异,统计2种不同示踪剂PET/CT显像在诊断HGG和LGG时的灵敏度、特异度和准确度。绘制受试者操作特征曲线并计算曲线下面积(AUC),评估2种示踪剂在胶质瘤分级中的诊断效能。(2)统计HGG组和LGG组中^(18)F-PSMA-1007 PET/CT和^(18)F-FDG PET/CT能够清晰显示病灶边界的病例数,比较2种显像方法在显示病灶边界清晰度上的差异。结果LGG组^(18)F-PSMA-1007 PET/CT和^(18)F-FDG PET/CT的SUVmax分别为0.69±0.32、8.87±3.20,TBR分别为1.05±0.45、0.89±0.30;HGG组^(18)F-PSMA-1007 PET/CT和^(18)F-FDG PET/CT的SUVmax分别为5.39±3.88、11.85±3.54,TBR分别为12.99±10.60、1.25±0.54。LGG组^(18)F-PSMA-1007 PET/CT和^(18)F-FDG PET/CT的SUVmax、TBR均小于HGG组,差异均有统计学意义(P值均<0.05)。^(18)F-PSMA-1007 PET/CT的SUVmax和TBR对HGG和LGG分级诊断的灵敏度、特异度、准确度和AUC均高于^(18)F-FDG PET/CT。^(18)F-PSMA-1007 PET/CT中TBR的AUC最高,为0.988(95%可信区间0.960~1.000),相应的阈值为2.15;^(18)F-FDG PET/CT TBR的AUC最低,为0.694(95%可信区间0.512~0.877),相应的阈值为0.97。^(18)F-PSMA-1007 PET/CT图像上HGG组和LGG组清晰显示病灶边界的病例均高于^(18)F-FDG PET/CT图像,差异均有统计学意义(P=0.039、0.016)。结论^(18)F-PSMA-1007 PET/CT在胶质瘤分级诊断中具有潜在的诊断价值。与^(18)F-FDG PET/CT相比,^(18)F-PSMA-1007 PET/CT在区分高级别和低级别脑胶质瘤时,具有更高的灵敏度、特异度、准确度和诊断效能,可更清晰地描绘病变边界。

关键词：神经胶质瘤正电子发射体层摄影/计算机体层成像 ^(18)F‐脱氧葡萄糖前列腺特异性膜抗原

Studies on the rheological, phase morphologic, thermal and mechanical properties of poly(trimethylene terephthalate)/ ethylene propylene diene monomer copolymer grafted with maleic anhydride/metallocene polyethylene blends

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Frontiers of Chemical Science and Engineering 2007年第3期1卷 238-245页

作者： RUN Mingtao SONG Hongzan WANG Yingjin YAO Chenguang gao jungang College of Chemistry&Environmental Science Hebei UniversityBaoding 071002China

The rheological,phase morphologic,thermal andmechanicalpropertiesofpoly(trimethyleneterephthalate)/metallocene polyethylene(PTT/mPE)blends in the presence of ethylene propylene diene monomer copolymer grafted with maleic anhydride(EPDM-g-MAH)as compatibilizer are studied by means of a capillary rheometer,scanning electron microscopy(SEM),differential scanning calorimetry(DSC)and thermogravimetric analyzer(TGA).Results suggest that the compatibility of PTT/mPE blends is improved greatly after the addition of a *** radius of the dispersed phase in the system decreases greatly when the compatibilizer is added into the *** the amount of compatibilizer exceeds 8 wt-%,the size of dispersed phase becomes larger *** phenomena could be attributed to the higher viscosity of the EPDM-g-MAH phase,which is dispersed more difficulty in the PTT phase of lower viscosity,thus the mixing efficiency is apparently decreased during the melt blending ***,the melt viscosity of the blend reaches the maximal value in case of 4 wt-%compati-bilizer content,above which it would decrease *** result is associated with the generation of more and bigger dispersed phase inside the bulk phase,thus the grafting efficiency at the interface is decreased,which could result in lower *** DSC results suggest that the mPE component shows a nucleating effect,and could increase the overall degree and rate of PTT crystallization,while the addition of a compatibilizer might slightly diminish these *** addition,the blend with 4 wt-%compatibilizer shows the best thermal ***,the Izod impact strength and the tensile strength at room temperature of the blend are also markedly improved by the addition of a 4–8 wt-%compatibilizer.

关键词： poly(trimethylene terephthalate) mPE EPDM-g-MAH rheology morphology

^(18)F-FDG PET/CT显像对肺癌骨转移、前列腺癌骨转移与多发性骨髓瘤的鉴别诊断

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中华解剖与临床杂志 2024年第1期29卷 1-8页

作者：高俊刚尚宇刘翔梁宇霞王博段小艺牛晨刘军西安交通大学第一附属医院医学影像科西安710061

目的探讨^(18)F-脱氧葡萄糖(^(18)F-FDG)正电子发射体层摄影(PET)/CT在肺癌骨转移、前列腺癌骨转移与多发性骨髓瘤(MM)鉴别诊断中的应用价值。方法横断面研究。纳入2020年11月—2022年11月西安交通大学第一附属医院均行^(18)F-FDG PET/C... 详细信息

目的探讨^(18)F-脱氧葡萄糖(^(18)F-FDG)正电子发射体层摄影(PET)/CT在肺癌骨转移、前列腺癌骨转移与多发性骨髓瘤(MM)鉴别诊断中的应用价值。方法横断面研究。纳入2020年11月—2022年11月西安交通大学第一附属医院均行^(18)F-FDG PET/CT检查的42例肺癌骨转移患者、30例前列腺癌骨转移患者和36例MM患者的临床资料,其中男78例、女30例,年龄33~87岁,分别纳入肺癌组、前列腺癌组和MM组。分析3组患者骨骼病灶的位置分布、骨质破坏类型和最大标准摄取值(SUVmax)的差异。结果3组患者年龄、性别比较,差异均有统计学意义(F=9.63、χ^(2)=17.17,P值均0.05)。病灶分布位置组间比较显示:前列腺癌组骨转移灶分布于骨盆、四肢者分别为96.7%(29/30)、53.3%(16/30),均多于肺癌组的71.4%(30/42)、19.0%(8/42),差异均有统计学意义(P值均<0.05);MM组病灶位于肋骨者[100%(36/36)]多于前列腺癌组[70%(21/30)],位于骨盆者[72.2%(26/36)]少于前列腺癌组[96.7%(29/30)]、位于颅骨者[55.6%(20/36)]多于前列腺癌组和肺癌组[6.7%(2/30)和4.8%(2/42)],差异均有统计学意义(P值均<0.05)。3组患者骨质破坏类型总体比较的差异有统计学意义(χ^(2)=82.94,P<0.001):肺癌组和MM组患者骨骼病灶的骨质破坏均以溶骨性病变为主[81.0%(34/42)和94.4%(34/36)],成骨性病变较少[7.1%(3/42)和2.8%(1/36)],还有部分混合性病变[11.9%(5/42)和2.8%(1/36)];前列腺癌组患者则以成骨性病变为主[90.0%(27/30)]。在代谢特征方面,肺癌组、前列腺癌组和MM组的SUVmax水平依次由高到低(F=54.66,P<0.001)。结论^(18)F-FDG PET/CT有助于综合评价肺癌骨转移、前列腺癌骨转移和MM病灶的骨质结构和代谢特征,对它们具有较高的鉴别诊断价值。

关键词：肺肿瘤前列腺肿瘤骨转移瘤多发性骨髓瘤正电子发射体层摄影/计算机体层成像 ^(18)F-脱氧葡萄糖

Assessment of Changes in the Value of Ecosystem Services in the Koshi River Basin,Central High Himalayas Based on Land Cover Changes and the CA-Markov Model

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Journal of Resources and Ecology 2017年第1期8卷 67-76页

作者： ZHAO Zhilong WU Xue ZHANG Yili gao jungang Key Laboratory of Land Surface Pattern and Simulation Institute of Geographic Sciences and Natural Resources Research Chinese Academy of Sciences Beijing 100101 China University of the Chinese Academy of Sciences Beijing 100049 China

Climate warming and economic developments have created pressures on the ecological systems that human populations rely on,and this process has contributed to the degradation of ecosystems and the loss of ecosystem *** this study,Landsat satellite data were chosen as the data source and the Koshi River Basin（KB） in the central high Himalayas as the study *** in land cover and changes in the value of ecosystem services between 1990 and 2010 were analyzed and the land cover pattern of the KB in 2030 and 2050 was modeled using the CA-Markov *** in land cover and in the value of ecosystem services in the KB for the period 2010–2050 were then *** value of ecosystem services in the KB was found to decrease by 2.05×10~8 USD y^（-1） between 1990 and *** these results,the services value of forest,snow/glacier and barren area decreased,while that of cropland *** 1990 to 2050,forest showed the largest reduction in ecosystem services value,as much as 11.87×10~8 USD y^（-1）,while cropland showed the greatest increase,by 3.05×10~8 USD y^（-1）.Deforestation and reclamation in Nepal contributed to a reduction in the value of ecosystem services in the *** areas that were transformed into water bodies brought about an increase in ecosystem services value in the lower reaches of the Koshi *** general,this process is likely to be related to increasing human activity in the KB.

关键词： ecosystem services CA-Markov land cover Himalayas Koshi River Basin

Kinetics of Reaction of Bromo-epoxy Resin with Oleic Acid catalyzed by Dimethyl benzyl amine

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Chemical Research in Chinese Universities 1992年第1期8卷 10-14页

作者： gao jungang, Yang Yan and Jing Jing (Department of Chemistry, Hebei University, Baoding)

The kinetics of reaction of bromo-epoxy resin with oleic acid in the presence of dimethylbenzylamine catalyst was studied. The reaction is a zero order reaction with respect to oleic acid, first order with respect to epoxy group and 0. 74 order with respect to dimethylbenzylamine. The reaction rate constants at various temperatures and activation energy were determined. The mechanism of this reaction was discussed. Keywords Tetrabromobisphenol-A, Bromo-epoxy resin, Oleic acid kinetics, Reaction mechanism

关键词： Kinetics of Reaction of Bromo-epoxy Resin with Oleic Acid catalyzed by Dimethyl benzyl amine

Kinetics of Reaction Bisphenol-S Epoxy Resin with Methylacrylic Acid

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Chemical Research in Chinese Universities 1989年第1期5卷 75-81页

作者： gao jungang, Wang Fengli, Jin Ruimin and Zhu Guiju (Department of Chemistry, Hebei University, Baoding)

The reaction kinetics of bisphenol-S epoxy resin with methyl-acrylic acid in the presence of quaternary ammonium salt catalyst was studied. The reaction rate constants at different temperatures were determined. The reaction is first order with respect to epoxy group, zero order with respect to methylacrylic acid and 0.71 order with respect to quaternary ammonium salt catalyst, respectively. The mechanism of this reaction was discussed.

关键词： Bisphenol-S epoxy resin Methylacrylic acid Kinetics Reaction mechanism

Vertical distribution changes in land cover between 1990 and 2015 within the Koshi River Basin,Central Himalayas

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Journal of Geographical Sciences 2021年第10期31卷 1419-1436页

作者： WU Xue PAUDEL Basanta ZHANG Yili LIU Linshan WANG Zhaofeng XIE Fangdi gao jungang SUN Xiaomin Key Laboratory of Land Surface Pattern and Simulation Institute of Geographic Sciences and Natural Resources ResearchCASBeijing 100101China Key Laboratory of Ecosystem Network Observation and Modeling Institute of Geographic Sciences and Natural Resources ResearchCASBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Texas A&M AgriLife Blackland Res&Extens CtrTempleTX 76502USA

The study of mountain vertical natural belts is an important component in the study of regional *** areas are especially sensitive to climate change and have indicative function,which is the core of three-dimensional zonality ***,based on high precision land cover and digital elevation model(DEM)data,and supported by MATLAB and ArcGIS analyses,this paper aimed to study the present situation and changes of the land cover vertical belts between 1990 and 2015 on the northern and southern slopes of the Koshi River Basin(KRB).Results showed that the vertical belts on both slopes were markedly different from one *** vertical belts on the southern slope were mainly dominated by cropland,forest,bare land,and glacier and snow *** contrast,grassland,bare land,sparse vegetation,glacier and snow cover dominated the northern *** found that the main vertical belts across the KRB within this region have not changed substantially over the past 25 *** contrast,on the southern slope,the upper limits of cropland and bare land have moved to higher elevation,while the lower limits of forest and glacier and snow cover have moved to higher *** upper limit of alpine grassland on the northern slope retreated and moved to higher elevation,while the lower limits of glacier and snow cover and vegetation moved northward to higher *** in the vertical belt were influenced by climate change and human activities over *** was mainly controlled by human activities and climate warming,and the reduced precipitation also led to the abandonment of cropland,at least to a certain *** in grassland and forest ecosystems were predominantly influenced by both human activities and climate *** the same time,glacier and snow cover far away from human activities was also mainly influenced by climate warming.

关键词： vertical belt land cover Central Himalayas Koshi River Basin climate change