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Stepping up after spinal cord injury:negotiating an obstacle during walking

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Neural Regeneration Research 2025年第7期20卷 1919-1929页

作者： Alain Frigon Charly g.Lecomte Department of Pharmacology-Physiology Faculty of Medicine and Health SciencesUniversitéde SherbrookeCentre de recherche du Centre Hospitalier Universitaire de SherbrookeSherbrookeQCCanada

Every day walking consists of frequent voluntary modifications in the gait pattern to negotiate *** spinal cord injury,stepping over an obstacle becomes *** over an obstacle requires sensorimotor transformations in several structures of the brain,including the parietal cortex,premotor cortex,and motor *** information and planning are transformed into motor commands,which are sent from the motor cortex to spinal neuronal circuits to alter limb trajectory,coordinate the limbs,and maintain *** spinal cord injury,bidirectional communication between the brain and spinal cord is disrupted and animals,including humans,fail to voluntarily modify limb trajectory to step over an ***,in this review,we discuss the neuromechanical control of stepping over an obstacle,why it fails after spinal cord injury,and how it recovers to a certain extent.

关键词： biomechanics locomotion neurophysiology obstacle negotiation spinal cord injury

Projective Hilbert modules and sequential approximations

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Science China Mathematics 2025年第1期 137-168页

作者： Lawrence g.Brown Huaxin Lin Department of Mathematics Purdue University Department of Mathematics East China Normal University Department of Mathematics University of Oregon Shanghai Institute for Mathematics and Interdisciplinary Sciences

We show that when A is a separable C*-algebra,every countably generated Hilbert A-module is projective（with bounded module maps as morphisms）.We also study the approximate extensions of bounded module *** the case where A is a σ-unital simple C*-algebra with strict comparison,and every strictly positive lower semicontinuous affine function on quasitraces can be realized as the rank of an element in the Cuntz semigroup,we show that the Cuntz semigroup is equivalent to unitarily equivalent classes of countably generated Hilbert A-modules if and only if A has stable rank one.

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Carbonates and organic matter in soils characterized by reflected energy from 350-25000 nm wavelength

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Journal of Mountain Science 2020年第7期17卷 1636-1651页

作者： Najmeh ASgARI Shamsollah AYOUBI Jose Alexandre Melo DEMATTê AndréCarnieletto dotto Department of Soil Science College of AgricultureIsfahan University of Technology841156-83111IsfahanIran Department of Soil Science College of Agriculture Luiz de QueirózAv.Pádua Dias11CEP 13418-900PiracicabaSão PauloBrazil

The soil carbon pool which is the sum of soil organic carbon(SOC)and soil inorganic carbon(SIC)is the second largest active store of carbon after the oceans and it is an important component of the global carbon ***,accurate estimation of SOC and SIC as important carbon reservoirs in terrestrial ecosystems using fast,inexpensive and non-destructive methods is crucial for planning different climate change *** aim of the current research was to examine the effectiveness of Vis-NIR(visible and near-infrared spectroscopy:350-2500 nm)and MIR(mid-infrared spectroscopy:4000-400 cm-1)to characterize and estimate soil organic matter(SOM)and carbonates as main components of soil carbon stocks in Juneqan,Charmahal va Bakhtiari,*** do so,a total of 548 soil samples from this area were collected(October 2015)and analyzed in laboratory(August 2017).In order to develop models capable of predicting SOM and carbonates content,seven spectral preprocessing methods comprising Absorbance(Abs),De-trending(Det),Continuum removal(CR),Savitzky-golay derivatives(SgD),standard normal variate transformation(SNV),multiplicative scatter correction(MSC)and Normalization by range(NBR)were conducted along with five multivariate methods including Random Forest(RF),Partial Least-Squares Regression(PLSR),Artificial Neural Network(ANN),Support Vector Machine(SVM)and gaussian Process Regression(gPR).The content of carbonates caused spectral reflectance intensity to augment on several ranges of spectrum and strong absorption feature at 2338 nm in the Vis-NIR and 714,850,870,1796,2150 and 2510 cm-1 in the MIR spectra *** absorbed energy in several ranges,but also showed specific peaks in *** facts are associated with the structure of carbonates and SOM and its interaction with *** best combination of preprocessing and calibration models for carbonates quantification in Vis-NIR spectra was Det/PLSR(R2=0.74,RPD=2.19,RMSE=6.45).For SOM,it was Det/PLSR(R2=0.82,RPD=2.41,RM

关键词： Modeling Reflectance spectroscopy Soil analysis Preprocessing

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角化上皮干细胞及癌变的Notch信号调控

中华口腔医学杂志 2009年第Z1期44卷 88-88页

作者： g.paol.dotto BostonMA DepartmentofBiochemistry MassachusettsgeneralHospital USA UniversityofLausanneandCutaneousBiologyResearchCenter

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Deposition of nanoparticles on school eyeglasses in urban and rural areas:A methodology for a more real assessment of the possible impacts

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geoscience Frontiers 2022年第1期13卷 498-505页

作者： Kátia Martinello James C.Hower guilherme L.dotto Claudete g.Ramos Carlos E.Schnorr Diana Pinto Instituto Inanís Rua Felizardo FurtadoPorto AlegreBrazil University of Kentucky Department of Earth&Environmental SciencesLexingtonKY 40506USA University of Kentucky Center for Applied Energy Research2540 Research Park DriveLexingtonKY 40511USA Chemical Engineering Department Federal University of Santa Maria97105-900 Santa MariaBrazil Department of Civil and Environmental Universidad de la CostaCUCCalle 58#55–66BarranquillaAtlánticoColombia

Because incomplete confirmation is available concerning the influential role of atmosphere contamination on conjunctivitis,myopia,asthma,and allergic rhinitis in Brazil,the focus of the present work is to explore the possible relations among atmosphere contamination and eye *** that a case study on eye diseases,by way of questionnaires supplemented by the investigation of nanoparticles(NPs)on eyeglasses,the study examines the mechanisms in which NPs and ultra-fine particles are deposited on the glasses of children up to 10 years of age in urban and rural *** important connection between atmosphere contaminants and individual protection equipment justifies improving indoor school properties in order could protect children’s eyes,particularly in high-pollution/high-particulate areas.

关键词： Indoor air pollution Nanoparticles Eyes health Allergic reaction Schools

Bioelectronic medicine in modulation of cortical spreading depolarization and beyond

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Neural Regeneration Research 2025年第2期20卷 481-482页

作者： Khaled Alok Timothy g.White Chunyan Li Department of Neurosurgery Donald and Barbara Zucker School of Medicine at Hofstra/NorthwellHempsteadNYUSA Translational Brain Research Laboratory The Feinstein Institutes for Medical ResearchManhassetNYUSA

Bioelectronic interventions,specifically trigeminal nerve st imulat ion(TNS),have attracted considerable attention in conditions where cortical spreading depolarizations(CSDs)accompanied by compromised cerebral perfusion may exacerbate neurological *** pharmacological interventions have demonstrated initial potential in addressing CSDs,a standardized treatment approach has not yet been *** objective of this perspective is to explore emerging bioelectronic methodologies for addressing CSDs,particularly emphasizing TNS,and to underscore TNS’s capacity to enhance neurovascular coupling and cerebral perfusion.

关键词： cerebral perfusion electronic

Nanomineralogy of evaporative precipitation of efflorescent compounds from coal mine drainage

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geoscience Frontiers 2021年第6期12卷 404-410页

作者： Luis F.O.Silva Diana Pinto guilherme L.dotto James C.Hower Department of Civil and Environmental.Universidad de La Costa CUCCalle 58#55–66BarranquillaAtlanticoColombia Universidade Federal de Santa Maria–UFSM 1000Roraima Avenue97105–900Santa MariaRSBrazil University of Kentucky Department of Earth&Environmental SciencesLexingtonKY40506USA University of Kentucky Center for Applied Energy Research2540 Research Park DriveLexingtonKY40511USA

Efflorescent nanophases(NPs) are found as a transitory accumulation of potentially hazardous elements(PHEs),particularly in tropical climates. The central objective of this study was to investigate the distribution of PHEs with NPs through the evaporative formation structures(EFS) of enormously PHEs-rich coal-mine drainages(CMD). The EFS were studied in natural coal mine drainage for five months in order to determine their geochemical and ecological structures and to assess their position in the reduction of PHEs in nature. The largest coal-fired power plant in South America, located in south Brazil, is used as an example of such a problem. In this work, a novel methodology for the analysis of PHEs in CMD precipitates is proposed for this affected coal *** analytical method, combining X-Ray Diffraction(XRD) and advanced electron microscopies, shows the importance of nanomineralogy in understanding different circumstances of coal contamination. Several ultrafinenanoparticles(UNPs) were identified in the sampled soils and river sediments together with the PHEs. A decrease in PHEs was identified in association with UNPs. However, further investigations are required with regard to the mobility of PHEs in water, atmosphere, soils, and sediments. The EPS was thoroughly studied, acquiring suitable understanding with investigational facts for Ca and Fe-sulphates, pickeringite, and several amorphous phases.

关键词： Coal mine drainage Evaporative precipitation Sediments Water and soil pollution

Impact of Zika virus non-structural protein mutations on hippocampal damage

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Neural Regeneration Research 2025年第8期20卷 2307-2308页

作者： Larissa M.g.Cassiano Roney S.Coimbra Neurogenômica/Imunopatologia Instituto RenéRachouFiocruzBelo HorizonteBrazil Departamento de Bioquímica e Imunologia Instituto de Ciências BiológicasUniversidade Federal de Minas GeraisBelo HorizonteBrazil

The Zika virus(ZIKV),a member of the Flaviviridae family,attracted worldwide attention for its connection to severe neurological effects,notably microcephaly in newborns,first reported during the 2015 epidemic in ***,its impact goes beyond fetal and neonatal abnormalities,also affecting the central nervous system(CNS)in both children and adults,leading to enduring cognitive and behavioral impairments.

关键词： damage fetal neonatal

Artisanal ceramic factories using wood combustion:A nanoparticles and human health study

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geoscience Frontiers 2022年第1期13卷 488-497页

作者： Kátia Martinello James C.Hower Diana Pinto Carlos E.Schnorr guilherme L.dotto Marcos Leandro Silva Oliveira Claudete g.Ramos Instituto Inanís Rua Felizardo FurtadoPorto AlegreBrazil Department of Civil and Environmental Universidad de la CostaCUCCalle 58#55–66BarranquillaAtlánticoColombia University of Kentucky Department of Earth&Environmental SciencesLexingtonKY 40506USA University of Kentucky Center for Applied Energy Research2540 Research Park DriveLexingtonKY 40511USA Centro de Estudos em Estresse Oxidativo-Departamento de Bioquímica-Instituto de Ciências Básicas da Saúde-Universidade Federal do Rio grande do Sul(UFRgS) Porto AlegreRSBrazil Chemical Engineering Department Federal University of Santa MariaUFSMRoraima Avenue1000Santa MariaRS97105-900Brazil Departamento de Ingeniería Civil y Arquitectura Universidad de LimaAvenida Javier Prado Este 4600–Santiago de Surco 1503Peru

The ceramics industry,resulting from developments of modern compounds,is a segment of great influence in worldwide *** ceramic factories based on wood combustion have significant risks for the creation and discharge of atmosphere nanoparticles(NPs)and ultra-fine particles(UFPs).At present,there is insufficient recognition on the influence of engineered-NPs on the atmosphere and *** improvements are indispensable to diminish contact with *** present study demonstrates the main NPs and UFPS present in an area of intense artisanal wood-combustion ceramic *** matter was sampled for morphological,chemical,and geochemical studies by sophisticated electron microbeam microscopy,X-Ray Diffraction,and Raman *** NPs configuration(10 nm)were produced around the studied artisanal ceramic *** study presents an indication of the recent information on population and work-related contact to NPs in the artisanal ceramic factories and their influence on health.

关键词： Ceramic manufacturing Nanoparticles Advanced characterization Multiple impacts