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Spectral broadening for multi-Joule pulse compression in the APOLLON Long Focal Area facility

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High Power Laser Science and Engineering 2022年第2期10卷 7-13页

作者： P.-g.Bleotu J.Wheeler D.Papadopoulos M.Chabanis J.Prudent M.Frotin L.Martin N.Lebas A.Freneaux A.Beluze F.Mathieu P.Audebert D.Ursescu J.Fuchs g.mourou LULI-CNRS CEASorbonne UniversiteEcole PolytechniqueInstitut Polytechnique de ParisF-91128 Palaiseau CedexFrance Faculty of Physics University of Bucharest077125 Bucharest-MagureleRomania Horia Hulubei National Institute for R&D in Physics and Nuclear Engineering(IFIN-HH) MagureleRO-077125Romania Independent Researcher F-92340 Bourg-La-ReineFrance IZEST Ecole PolytechniqueInstitut Polytechnique de ParisF-91128 Palaiseau CedexFrance

Spectral-broadening of the APOLLON PW-class laser pulses using a thin-film compression technique within the longfocal-area interaction chamber of the APOLLON laser facility is reported,demonstrating the delivery of the full energy pulse to the target interaction *** laser pulse at 7 J passing through large aperture,thin glass wafers is spectrally broadened to a bandwidth that is compatible with a 15-fs pulse,indicating also the possibility to achieve sub-10-fs pulses using 14 *** the post-compressor near the interaction makes for an economical method to produce the shortest pulses by limiting the need for high damage,broadband optics close to the final target rather than throughout the entire laser transport system.

关键词： high energy post-compression nonlinear pulse interaction high-power laser laser diagnostics

Post-compression of high-energy,sub-picosecond laser pulses

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High Power Laser Science and Engineering 2023年第2期11卷 117-126页

作者： P.-g.Bleotu J.Wheeler S.Yu.Mironov V.ginzburg M.Masruri A.Naziru R.Secareanu D.Ursescu F.Perez J.De Sousa D.Badarau E.Veuillot P.Audebert E.Khazanov g.mourou LULI-CNRS CEAUniversite SorbonneEcole PolytechniqueInstitut Polytechnique de ParisPalaiseau CEDEXFrance Doctoral School of Physics University of BucharestBucharest-MagureleRomania Horia Hulubei National Institute for R&D in Physics and Nuclear Engineering(IFIN-HH) MagureleRomania IZEST Ecole PolytechniqueInstitut Polytechnique de ParisPalaiseau CEDEXFrance Independent Researcher Bourg-La-ReineFrance Federal Research Center Institute of Applied Physics of the Russian Academy of Sciences(IAP RAS) Nizhny NovgorodRussia

The post-compression technique based on self-phase modulation of high-energy pulses leads to an increase in achievable peak power and ***,the pulses considered in experiments have been less than 100 fs in ***,the method is applied to the ELFIE laser system at the LULI facility,for a pulse of 7 J energy and an initial measured duration of 350 fs.A 5-mm-thick fused silica window and a 2 mm cyclic-olefin polymer were used as optical nonlinear *** 9 cm diameter beam was spectrally broadened to a bandwidth corresponding to 124 fs Fourier-limited pulse duration,and then it was partly post-compressed to 200 *** measuring the spatial spectra of the beam fluence,a uniform gain factor of 4 increase in the fluctuations over the studied range of frequencies is observed,due to small-scale self-focusing.

关键词： high-power laser nonlinear pulse interaction post-compression self-phase modulation

Stepping up after spinal cord injury:negotiating an obstacle during walking

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Neural Regeneration Research 2025年第7期20卷 1919-1929页

作者： Alain Frigon Charly g.Lecomte Department of Pharmacology-Physiology Faculty of Medicine and Health SciencesUniversitéde SherbrookeCentre de recherche du Centre Hospitalier Universitaire de SherbrookeSherbrookeQCCanada

Every day walking consists of frequent voluntary modifications in the gait pattern to negotiate *** spinal cord injury,stepping over an obstacle becomes *** over an obstacle requires sensorimotor transformations in several structures of the brain,including the parietal cortex,premotor cortex,and motor *** information and planning are transformed into motor commands,which are sent from the motor cortex to spinal neuronal circuits to alter limb trajectory,coordinate the limbs,and maintain *** spinal cord injury,bidirectional communication between the brain and spinal cord is disrupted and animals,including humans,fail to voluntarily modify limb trajectory to step over an ***,in this review,we discuss the neuromechanical control of stepping over an obstacle,why it fails after spinal cord injury,and how it recovers to a certain extent.

关键词： biomechanics locomotion neurophysiology obstacle negotiation spinal cord injury

An SPH Framework for Earthquake-Induced Liquefaction Hazard Assessment of geotechnical Structures

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 251-277页

作者： Sourabh Mhaski g.V.Ramana Department of Civil Engineering Indian Institute of Technology DelhiNew Delhi110016India

Earthquake-induced soil liquefaction poses significant risks to the stability of geotechnical structures *** understanding of the liquefaction triggering,and the post-failure large deformation behaviour is essential for designing resilient *** present study develops a Smoothed Particle Hydrodynamics(SPH)framework for earthquake-induced liquefaction hazard assessment of geotechnical *** coupled flowdeformation behaviour of soils subjected to cyclic loading is described using the PM4Sand model implemented in a three-phase,single-layer SPH framework.A staggered discretisation scheme based on the stress particle SPH approach is adopted to minimise numerical inaccuracies caused by zero-energy modes and tensile ***,non-reflecting boundary conditions for seismic analysis of semi-infinite soil domains using the SPH method are *** numerical framework is employed for the analysis of cyclic direct simple shear test,seismic analysis of a level ground site,and liquefaction-induced failure of the Lower San Fernando *** agreement for liquefaction triggering and post-failure behaviour demonstrates that the SPH framework can be utilised to assess the effect of seismic loading on field-scale geotechnical *** present study also serves as the basis for future advancements of the SPH method for applications related to earthquake geotechnical engineering.

关键词： Earthquake seismic liquefaction stress particle PM4Sand smoothed particle hydrodynamics(SPH)

Bioelectronic medicine in modulation of cortical spreading depolarization and beyond

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Neural Regeneration Research 2025年第2期20卷 481-482页

作者： Khaled Alok Timothy g.White Chunyan Li Department of Neurosurgery Donald and Barbara Zucker School of Medicine at Hofstra/NorthwellHempsteadNYUSA Translational Brain Research Laboratory The Feinstein Institutes for Medical ResearchManhassetNYUSA

Bioelectronic interventions,specifically trigeminal nerve st imulat ion(TNS),have attracted considerable attention in conditions where cortical spreading depolarizations(CSDs)accompanied by compromised cerebral perfusion may exacerbate neurological *** pharmacological interventions have demonstrated initial potential in addressing CSDs,a standardized treatment approach has not yet been *** objective of this perspective is to explore emerging bioelectronic methodologies for addressing CSDs,particularly emphasizing TNS,and to underscore TNS’s capacity to enhance neurovascular coupling and cerebral perfusion.

关键词： cerebral perfusion electronic

Impact of Zika virus non-structural protein mutations on hippocampal damage

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Neural Regeneration Research 2025年第8期20卷 2307-2308页

作者： Larissa M.g.Cassiano Roney S.Coimbra Neurogenômica/Imunopatologia Instituto RenéRachouFiocruzBelo HorizonteBrazil Departamento de Bioquímica e Imunologia Instituto de Ciências BiológicasUniversidade Federal de Minas GeraisBelo HorizonteBrazil

The Zika virus(ZIKV),a member of the Flaviviridae family,attracted worldwide attention for its connection to severe neurological effects,notably microcephaly in newborns,first reported during the 2015 epidemic in ***,its impact goes beyond fetal and neonatal abnormalities,also affecting the central nervous system(CNS)in both children and adults,leading to enduring cognitive and behavioral impairments.

关键词： damage fetal neonatal

Xiamen after 20 Years of Ecological Transformation

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China Today 2025年第1期74卷 66-68页

作者： ZACHARY g.LUNDQUIST 不详

The efforts Xiamen has made in ecological protection over the last 20 years have helped it become a beautiful and clean *** years ago,I had the opportunity to travel to the city of Xiamen in southeastern China’s Fujian ***,due to the fact that I was in a rush,I did not have the chance to see the whole *** memory of Xiamen was its pleasant climate and unforgettable beauty-I knew if I ever got the opportunity,I would revisit this *** years went by until I was able to return to this city *** emerging from the airport,I realized that I had grown older,while Xiamen was becoming increasingly youthful and *** exactly had given this city such vitality?

关键词： Ecological Xiamen Transformation

Heterogeneity of mature oligodendrocytes in the central nervous system

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Neural Regeneration Research 2025年第5期20卷 1336-1349页

作者： Chao Weng Adam M.R.groh Moein Yaqubi Qiao-Ling Cui Jo Anne Stratton g.R.Wayne Moore Jack P.Antel Neuroimmunology Unit Montreal Neurological Institute-HospitalDepartment of Neurology and NeurosurgeryMcGill UniversityMontrealQCCanada Department of Neurology Renmin Hospital of Wuhan UniversityWuhanHubei ProvinceChina

Mature oligodendrocytes form myelin sheaths that are crucial for the insulation of axons and efficient signal transmission in the central nervous *** evidence has challenged the classical view of the functionally static mature oligodendrocyte and revealed a gamut of dynamic functions such as the ability to modulate neuronal circuitry and provide metabolic support to *** the recognition of potential heterogeneity in mature oligodendrocyte function,a comprehensive summary of mature oligodendrocyte diversity is *** delve into early 20th-century studies by Robertson and Río-Hortega that laid the foundation for the modern identification of regional and morphological heterogeneity in mature ***,recent morphologic and functional studies call into question the long-assumed homogeneity of mature oligodendrocyte function through the identification of distinct subtypes with varying myelination ***,modern molecular investigations,employing techniques such as single cell/nucleus RNA sequencing,consistently unveil at least six mature oligodendrocyte subpopulations in the human central nervous system that are highly transcriptomically diverse and vary with central nervous system *** and disease related mature oligodendrocyte variation denotes the impact of pathological conditions such as multiple sclerosis,Alzheimer's disease,and psychiatric ***,caution is warranted when subclassifying mature oligodendrocytes because of the simplification needed to make conclusions about cell identity from temporally confined *** studies leveraging advanced techniques like spatial transcriptomics and single-cell proteomics promise a more nuanced understanding of mature oligodendrocyte *** research avenues that precisely evaluate mature oligodendrocyte heterogeneity with care to understand the mitigating influence of species,sex,central nervous system region,age,and disease,

关键词： aging central nervous system diseases electron microscopy heterogeneity immunohistochemistry myelin sheath natural history neuroglia oligodendroglia single-cell gene expression analysis

Equivalence of <i>K</i>-Functionals and Modulus of Smoothness generated by a generalized Dunkl Operator on the Real Line

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Advances in Pure Mathematics 2015年第6期5卷 367-376页

作者： Reem Fahad Al Subaie Mohamed Ali mourou Department of Mathematics College of Sciences for Girls University of Dammam Dammam Kingdom of Saudi Arabia Department of Mathematics Faculty of Sciences of Monastir University of Monastir Monastir Tunisia

This paper is intended to establish the equivalence between K-functionals and modulus of smoothness tied to a Dunkl type operator on the real line.

关键词： Differential-Difference Operator generalized Fourier Transform generalized Translation Operators K-Functionals Modulus of Smoothness