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Nucleotide Sequence and Characterization of Bovine Metallothionein gene

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Chinese Science Bulletin 1993年第5期38卷 419-423页

作者：杨靖沈孝宙杨卫民 M.g.Peterson J.F.B.Mercer Savio l.C.woo Institute of Developmental Biology Academia Sinica Beijing 100080 PRC. laboratory of Reproductive Biology Institute of Zoology Academia Sinica Beijing 100080 PRC Birth Defects Research Institute Poyal Children's Hospital Parkville Australia Department of Cell Biology Baylor College of Medicine Houston TX 77030 USA

1 Introduction Metallothioneins (MTs) are a family of low-molecular weight heavy metal binding proteins, unique in their high cystein content. MTs are ubiquitously distributed in the eukaryote from yeast to human. It is an experimental model emphasized during researching gene expression and regulation of animal cells. In order to provide inducible regulatory elements for transgenosis livestock, we cloned bovine MT genes. At least four members of bovine MT family have been discovered. In this note, one gene (bMTc) of

关键词： bovine metallothionein gene DNA sequence gene structure.

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二维范德华磁体的拓扑自旋结构的研究进展

Science Bulletin 2024年第11期69卷 1612-1616页

作者：许洪军刘艺舟 giovanni Finocchio Kang lwang 于国强 Beijing National laboratory for Condensed Matter Physics Institute of PhysicsUniversity of Chinese Academy of SciencesChinese Academy of SciencesBeijing 100190China RIKEN Center for Emergent Matter Science(CEMS) Wako 351-0198Japan Department of Mathematical and Computer Sciences Physical Sciences and Earth SciencesUniversity of MessinaMessina 98166Italy Department of Electrical Engineering University of CaliforniaLos Angeles CA 90095USA

The importance of topological spin textures(TSTs), such as skyrmions, merons, hopfions, etc., is due to their static and dynamic properties [1]. They carry a topological number that characterizes the homotopy group Π_(n)(S^(2))(n ∈ Z) and classifies maps from S^(n) to S^(2)(e.g., the skyrmion winding number corresponds to Π_(2)(S^(2))).

关键词：自旋结构 topological homotopy

NUMERICAl SIMUlATION OF SUCCINONITRITE DENDRITIC gROwTH IN A FORCED FlOw

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Acta Metallurgica Sinica(English letters) 2008年第6期21卷 444-450页

作者： Z. Chen C.l. Chen l.M. Hao School of Science Department of Applied Physics Shaanxi Key Laboratory of Condensed Matter Structures and Properties Northwestern Polytechnical University Xi＇an 710072 China School of Science Xi＇an University of Science ＆ Technology Xi＇an 710054 China

Numerical simulation based on phase field method is performed to describe solidification process of pure material in a free or forced flow. The evolution of the interface is showed, and the effects of mesh grid and flow velocity on succinonitrite shape are studied. These results indicate that crystal grows into an equiaxial dendrite in a free flow and into an asymmetrical dendritic in a forced flow. with increasing flow velocity, the upstream dendritic arm tip grows faster and the downstream arm grows slower. However, the evolution of the perpendicular tip has no significant change. In addition, mesh grid has no influence on dendritic growth shape when mesh grid is above 300×300.

关键词： Phase field method Forced flow Dendritic Succinonitrite Tip velocity

STRATEgIC DECISION MAKINg FOR IMPROVED ENVIRONMENTAl SECURITY:COAlITIONS AND ATTITUDES

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Journal of Systems Science and Systems Engineering 2009年第4期18卷 461-476页

作者： Sean BERNATH wAlKER Keith w.HIPEl Takehiro INOHARA Department of Systems Design Engineering University of Waterloo Department of Decision and Value Science Tokyo Institute of Technology

The utilization of decision support systems which are flexible enough to handle information about cooperative behavior and stakeholder attitudes are useful for analyzing complex social conflicts. One such conflict which arose from the redevelopment of a private brownfield property in Kitchener, Ontario, Canada is examined using such a decision support tool. Specifically, a formal model referred to as COAT which allows for the examination of conflicts with both coalition and attitude properties is rigorously defined and then implemented within the framework of the graph Model for Conflict Resolution in order that insights may be gained on how the decision makers can reach win-win resolutions.

关键词： graph model for conflict resolution attitudes coalitions COAT decision support system conflict

CYP1B1-derived epoxides modulate the TRPA1channel in chronic pain

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Acta Pharmaceutica Sinica B 2023年第1期13卷 68-81页

作者： lili Sun Jie Zhang Changshan Niu Cassandra E.Deering-Rice Ronald w.Hughen John g.lamb Katherine Rose Kevin M.Chase Marysol Almestica-Roberts Markel walter Eric w.Schmidt Alan R.light Baldomero M.Olivera Christopher A.Reilly Department of Pharmacology and Toxicology Center for Human ToxicologyUniversity of UtahSalt Lake CityUT84112USA Department of Anesthesiology School of MedicineUniversity of UtahSalt Lake CityUT 84112USA Department of Medicinal Chemistry University of UtahSalt Lake CityUT 84112USA School of Biological Sciences University of UtahSalt Lake CityUT 84112USA

Pain is often debilitating,and current treatments are neither universally efficacious nor without *** receptor potential(TRP)ion channels offer alternative targets for pain relief,but little is known about the regulation or identities of endogenous TRP ligands that affect inflammation and ***,transcriptomic and targeted lipidomic analysis of damaged tissue from the mouse spinal nerve ligation(SNl)-induced chronic pain model revealed a time-dependent increase in Cyp1b1 mRNA and a concurrent accumulation of 8,9-epoxyeicosatrienoic acid(EET)and 19,20-EpDPA post *** of 8,9-EET and 19,20-EpDPA by human/mouse CYP1B1 was confirmed in vitro,and 8,9-EET and 19,20-EpDPA selectively and dose-dependently sensitized and activated TRPA1 in overexpressing HEK-293 cells and Trpa1-expressing/AITC-responsive cultured mouse peptidergic dorsal root ganglia(DRg)***1 activation by 8,9-EET and 19,20-EpDPA was attenuated by the antagonist A967079,and mouse TRPA1 was more responsive to 8,9-EET and 19,20-EpDPA than human *** latter effect mapped to residues Y933,g939,and S921 of ***-plantar injection of 19,20-EpDPA induced acute mechanical,but not thermal hypersensitivity in mice,which was also blocked by ***,Cyp1b1-knockout mice displayed a reduced chronic pain phenotype following SNl *** data suggest that manipulation of the CYP1B1-oxylipin-TRPA1 axis might have therapeutic benefit.

关键词： CYPIB1 Spinal nerve ligation Epoxides TRPA1 Calcium imaging Hyperalgesia Chronic pain Inflammation

Rheological Regime of the Upper Mantle beneath the Taiwan Strait and Its Tectonic Significance

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Acta geologica Sinica(English Edition) 1995年第3期69卷 259-271,340页

作者： H.w.greenⅡ U яivetsity of California RiuersideC A 92521U.S.A.

This paper deals with deformation textures and fabrics of mantle-derived xenoliths and dislocation microstructures of olivine in the upper mantle in the Penghu Islands, Taiwan. According to the calculation of the chemical composition of xenolith minerals (pyroxene), the equilibrium temperatures and pressures were 986-1116@ and 1.50-2.60 gPa, respectively. Deformation events in the upper mantle may fall into three sequences' (1) uniform steady-state flow deformation with high temperatures and low stresses, (2) shear flow deformation with high temperatures and relatively high stresses on diapiric margins of the upper mantle, and (3) extraction deformation of {110} glide bands with low temperatures and high strain rates. Deformation events and thermal structure of the upper mantle in the study area show that eastern Fujian and the Penghu Islands are characterized by very similar rheological properties of the upper mantle. Volcanism of basalts in the Penghu Islands is related to hot spots of the upper mantle under neath the Taiwan Strait, and diapirism and upwelling of the upper mantle are the dominant factors responsible for rifting of the continental margins in eastern China.

关键词： mantle-derived xenolith high-temperature creep rheology of the upper mantle rifting Penghu Islands

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英格兰景观的形成

2018年

作者： (英)w. g.霍斯金斯

来源：南通市图书馆图书评论

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边缘竞争:变革时代的黄金竞争法则

董事会 2024年第8期 90-94页

作者：肖纳·l.布朗凯瑟琳·M.艾森哈特刘玉青(译) 覃宇(译) 不详

裁员、调整、重组……管理者们已经意识到精简业务只是“万里长征”的第一步。为了实现企业的繁荣与发展,他们把目光转向更本质的问题——战略。所谓战略,从根本上讲,就是决定业务发展方向以及到达的路径。传统的战略方法侧重于“业务... 详细信息

裁员、调整、重组……管理者们已经意识到精简业务只是“万里长征”的第一步。为了实现企业的繁荣与发展,他们把目光转向更本质的问题——战略。所谓战略,从根本上讲,就是决定业务发展方向以及到达的路径。传统的战略方法侧重于“业务要达成什么样的目标”。然而,传统的战略方法在面对变化迅速且难以预测的行业时往往显得束手无策。

关键词：竞争法则变革时代业务发展方向边缘竞争繁荣与发展管理者

维普期刊数据库博看期刊

首钢新建达涅利6辊3C轧机冷轧设计创新概念

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钢铁 2004年第6期39卷 51-54页

作者： l.Vignolo g.DelFrate 达涅利威恩联合公司

通过轧辊的交叉和轴向窜动的独创设计 ,达涅利 6辊 3CTM轧机实现了超大范围控制。除了中间辊弯辊和工作辊的正负弯辊外 ,轧机会在处于临界轧制状态时自动执行中间辊交叉。此外 ,机座还配备了工作辊轴向窜动 ,以便有效地控制带钢边部减... 详细信息

通过轧辊的交叉和轴向窜动的独创设计 ,达涅利 6辊 3CTM轧机实现了超大范围控制。除了中间辊弯辊和工作辊的正负弯辊外 ,轧机会在处于临界轧制状态时自动执行中间辊交叉。此外 ,机座还配备了工作辊轴向窜动 ,以便有效地控制带钢边部减薄。轧制力的有利分布 ,也优化了工作辊的磨损 ,从而降低了生产成本 ,提高了效率。

关键词：中间辊交叉板形控制