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Role of endoscopy in the bariatric surgery of patients

World Journal of gastroenterology 2014年第24期20卷 7777-7784页

作者： giovanni D de Palma pietro Forestieri Center of Excellence for Technical Innovation in Surgery Department of Clinical Medicine and SurgeryUniversity of Naples Federico ⅡSchool of Medicine80131 NaplesItaly department of Clinical Medicine and Surgery University of Naples Federico ⅡSchool of Medicine80131 NaplesItaly

Obesity is an increasingly serious health problem in nearly all Western countries. It represents an important risk factor for several gastrointestinal diseases, such as gastroesophageal reflux disease, erosive esophagitis, hiatal hernia, Barrett’s esophagus, esophageal adenocarcinoma, Helicobacter pylori infection, colorectal polyps and cancer, non-alcoholic fatty liver disease, cirrhosis, and hepatocellular carcinoma. Surgery is the most effective treatment to date, resulting in sustainable and significant weight loss, along with the resolution of metabolic comorbidities in up to 80% of cases. Many of these conditions can be clinically relevant and have a significant impact on patients undergoing bariatric surgery. There is evidence that the chosen procedure might be changed if specific pathological upper gastrointestinal findings, such as large hiatal hernia or Barrett’s esophagus, are detected preoperatively. The value of a routine endoscopy before bariatric surgery in asymptomatic patients (screening esophagogastroduodenoscopy) remains controversial. The common indications for endoscopy in the postoperative bariatric patient include the evaluation of symptoms, the management of complications, and the evaluation of weight loss failure. It is of critical importance for the endoscopist to be familiar with the postoperative anatomy and to work in close collaboration with bariatric surgery colleagues in order to maximize the outcome and safety of endoscopy in this setting. The purpose of this article is to review the role of the endoscopist in a multidisciplinary obesity center as it pertains to the preoperative and postoperative management of bariatric surgery patients.

关键词： Morbid obesity Obesity surgery Endoscopy Complications Endoscopic therapy

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Synergy of human platelet lysate and laminin to enhance the neurotrophic effect of human adipose-derived stem cells

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Neural Regeneration Research 2022年第10期17卷 2200-2202页

作者： pietro g di Summa Srinivas Madduri department of Plastic Reconstructive and Hand SurgeryUniversity Hospital of LausanneUniversity of LausanneLausanneSwitzerland department of Surgery Bioengineering and NeuroregenerationUniversity of GenevaUniversity Hospital GenevaGenevaSwitzerland

despite the spontaneous regenerative capacity of the peripheral nervous system,clinical nerve repair often results in poor functional recovery with the high socio-economic *** presence of peripheral nerve injuries and when distal nerve transfers are not possible,nerve autografts,are the solution of choice to cross a critical nerve ***,these are associated with donor site morbidity and offer only suboptimal functional ***,the need to improve the rate of effective regeneration has directed research attention towards stem cell therapy and nerve tissue engineering.

关键词： injuries donor spite

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Soil loss and runoff obtained with customized precipitation patterns simulated by InfiAsper

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International Soil and Water Conservation Research 2022年第3期10卷 407-413页

作者： Daniel Fonseca de Carvalho pietro Menezes Sanchez Macedo Marinaldo Ferreira Pinto Wilk Sampaio de Almeida Nivaldo Schultz department of Engineering Institute of TechnologyFederal Rural University of Rio de JaneiroSeropedicaRio de JaneiroBrazil Postgraduate Program in Agronomy-Soil Sciences Federal Rural University of Rio de JaneiroSeropedicaRio de JaneiroBrazil Agronomy department Federal Institute of EducationScience and Technology of RondoniaCampus AriquemesRO 257Km 13AriquemesRO76870-000Brazil department of Soil Science Institute of AgronomyFederal Rural University of Rio de JaneiroSeropedicaRJBrazil

Applying constant precipitation intensity,which does not occur in natural events,is one of the main limitations concerning rainfall simulators in soil erosion *** present work evaluated the InfiAsper rainfall simulator operating with a new control panel to program rainfalls with different precipitation intensities(PI).Infiltration rates and soil and water losses were evaluated in a Distrophic Acrisol(clay loam texture)with simulated rainfalls of 30 mm and duration of 40 min,considering advanced(AD),intermediate(IN),delayed(de),and inverted intermediate(II)patterns,all with PI peaks of 110 mm h^(-1),and a constant(CT)*** experimental design was in randomized blocks with five treatments(rainfall patterns)and experimental units measuring 2.5×2.5 *** simulator worked satisfactorily,applying the rainfall according to the preconfigured *** simulated rainfall with the CT and II patterns did not promote runoff nor soil *** and runoff rates varied according to the applied rainfall pattern,reaching 97.8 and 27.3 mm h^(-1)(AD),82.1 and 39.5 mm h^(-1)(IN),and 76.2 and 49.7 mm h^(-1)(de),*** loss and surface runoff totaled each 4.77 g m^(-2)and 3.9 mm(AD),6.70 g m^(-2)and 6.8 mm(IN),and 6.03 g m^(-2)and 7.0 mm(de).The InfiAsper simulator modified enables varying precipitation intensity besides obtaining satisfactory results in the field and information consistent with the expected characteristics of natural rainfall *** the intermediate and delayed rainfall patterns,soil and water losses are higher than in the advanced.

关键词： Water erosion Rainfall simulator Precipitation intensity

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Mulching as best management practice to reduce surface runoff and erosion in steep clayey olive groves

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International Soil and Water Conservation Research 2021年第1期9卷 26-36页

作者： giuseppe Bombino pietro denisi JoséAlfonso gómez demetrio Antonio Zema Mediterranea University of Reggio Calabria Department"Agraria"LocalitàFeo di Vito1-89122Reggio CalabriaItaly Institute for Sustainable Agriculture(IAS-CSIC) Agronomy DepartmentAvenida Menéndez Pidal s/nE-14004CórdobaSpain

No-tillage and soil mulching with pruning residues,applied in olive groves of the semi-arid Mediter-ranean environment,as erosion control practices still practice not fully *** study has evaluated the saturated hydraulic conductivity(Ksat),surface runoff(SR)and soil erosion(SL)under rainfall at plot scale throughout two years in four different management practices,total soil cover with a net(SP),mechanical tillage(MT)and mulching by vegetal residues at 3,5·10^(3) and 17,5·10^(3) kg ha^(-1) of dry matter(NTR350 and NTR1750),in an olive grove of Southern *** varied between 1.6(MT)and 25.1(NTR1750)mm/h.A clear reduction in runoff and soil losses was detected for the mulch-based practices when compared to MT,from 20 to 32%in the runoff coefficient and 75-80%in SL,with higher reductions in the *** reduction in SL can be mainly explained by the reduction in SR and rain-splash,interrill and rill erosion,due to protection by mulch residues,which increased the vegetal cover and organic matter content of mulched *** vegetal cover was on average higher in SP(33%),NTR1750(25%)and NTR350(22%),and lower in MT(12%).The mean organic matter content of soil was 2.01%,1.69%,1.34%and 0.82%for NTR1750,NTR350,SP and MT ***,the results quantify the impact of soil mulching with pruning residues at different doses,which will provide guidelines to control and mitigate the hydrological response of clayey and steep soils in Mediterranean olive groves,analysing the associated environmental and economic benefits.

关键词： Pruning residues Tillage Soil loss Vegetal cover Organic matter Soil hydraulic conductivity

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Measurement of the integrated luminosity of the Phase 2 data of the Belle Ⅱ experiment

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Chinese Physics C 2020年第2期44卷 1-12页

作者： F.Abudinén I.Adachi P.Ahlburg H.Aihara N.Akopov A.Aloisio F.Ameli L.Andricek N.Anh Ky D.M.Asner H.Atmacan T.Aushev V.Aushev T.Aziz K.Azmi V.Babu S.Baehr S.Bahinipati A.M.Bakich P.Bambade Sw.Banerjee S.Bansal V.Bansal M.Barrett J.Baudot A.Beaulieu J.Becker P.K.Behera J.V.Bennett E.Bernieri F.U.Bernlochner M.Bertemes M.Bessner S.Bettarini V.Bhardwaj F.Bianchi T.Bilka S.Bilokin D.Biswas g.Bonvicini A.Bozek M.Bračko P.Branchini N.Braun T.E.Browder A.Budano S.Bussino M.Campajola L.Cao g.Casarosa C.Cecchi D.Červenkov M.-C.Chang P.Chang R.Cheaib V.Chekelian Y.Q.Chen Y.-T.Chen B.g.Cheon K.Chilikin H.-E.Cho K.Cho S.Cho S.-K.Choi S.Choudhury D.Cinabro L.Corona L.M.Cremaldi S.Cunliffe T.Czank F.Dattola E.de La Cruz-Burelo g.de Nardo M.de Nuccio g.de pietro R.de Sangro M.destefanis S.dey A.de Yta-Hernandez F.Di Capua S.Di Carlo J.Dingfelder Z.Doležal I.Domínguez Jiménez T.V.Dong K.Dort S.Dubey S.Duell S.Eidelman M.Eliachevitch T.Ferber D.Ferlewicz g.Finocchiaro S.Fiore A.Fodor F.Forti A.Frey B.g.Fulsom M.gabriel E.ganiev M.garcia-Hernandez R.garg A.garmash V.gaur A.gaz U.gebauer A.gellrich J.gemmler T.geßler R.giordano A.giri B.gobbo R.godang P.goldenzweig B.golob P.gomis P.grace W.gradl E.graziani D.greenwald C.Hadjivasiliou S.Halder K.Hara T.Hara O.Hartbrich K.Hayasaka H.Hayashii C.Hearty M.T.Hedges I.Heredia de la Cruz M.Hernández Villanueva A.Hershenhorn T.Higuchi E.C.Hill H.Hirata M.Hoek S.Hollitt T.Hotta C.-L.Hsu Y.Hu K.Huang T.Iijima K.Inami g.Inguglia J.Irakkathil Jabbar A.Ishikawa R.Itoh M.Iwasaki Y.Iwasaki S.Iwata P.Jackson W.W.Jacobs D.E.Jaffe E.-J.Jang H.B.Jeon S.Jia Y.Jin C.Joo J.Kahn H.Kakuno A.B.Kaliyar g.Karyan Y.Kato T.Kawasaki H.Kichimi C.Kiesling B.H.Kim C.-H.Kim D.Y.Kim S.-H.Kim Y.K.Kim Y.Kim T.D.Kimmel K.Kinoshita C.Kleinwort B.Knysh P.Kodyš T.Koga I.Komarov T.Konno S.Korpar D.Kotchetkov N.Kovalchuk T.M.g.Kraetzschmar P.Križan R.Kroeger J.F.Krohn P.Krokovny W.Kuehn T.Kuhr M.Kumar R.Kumar K.Kumara S.Kurz A.Kuzmin Y.-J.Kwon S.Lacaprara Y.-T.Lai C.La Licata K.Lalwani L.Lanceri J.S.Lange K.Lautenbach I.-S.Le Beihang University Beijing 100191 Brookhaven National Laboratory UptonNew York 11973 Budker Institute of Nuclear Physics SB RAS Novosibirsk 630090 Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional Mexico City 07360 Faculty of Mathematics and Physics Charles University12116 Prague Chiba University Chiba 263-8522 Consejo Nacional de Ciencia y Tecnología Mexico City 03940 deutsches Elektronen–Synchrotron 22607 Hamburg Duke University DurhamNorth Carolina 27708 Earthquake Research Institute University of TokyoTokyo 113-0032 Forschungszentrum Jülich 52425 Jülich department of Physics Fu Jen Catholic UniversityTaipei 24205 Key Laboratory of Nuclear Physics and Ion-beam Application(MOE)and Institute of Modern Physics Fudan UniversityShanghai 200443 II.Physikalisches Institut Georg-August-Universität Göttingen37073 Göttingen gifu University Gifu 501-1193 The graduate University for Advanced Studies(SOKENDAI) Hayama 240-0193 gyeongsang National University Jinju 52828 department of Physics and Institute of Natural Sciences Hanyang UniversitySeoul 04763 High Energy Accelerator Research Organization(KEK) Tsukuba 305-0801 J-PARC Branch KEK Theory CenterHigh Energy Accelerator Research Organization(KEK)Tsukuba 305-0801 Indian Institute of Science Education and Research Mohali SAS Nagar140306 Indian Institute of Technology Bhubaneswar Satya Nagar 751007 Indian Institute of Technology Hyderabad Telangana 502285 Indian Institute of Technology Madras Chennai 600036 Indiana University BloomingtonIndiana 47408 Institute for High Energy Physics Protvino 142281 Institute of High Energy Physics Vienna 1050 Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049 Institute of Particle Physics(Canada) VictoriaBritish Columbia V8W 2Y2 Institute of Physics Hanoi Instituto de Fisica Corpuscular Paterna 46980 INFN Laboratori Nazionali di Frascati I-00044 Frascati INFN Sezione di Napoli I-80126 Napoli INFN Sezione di Padova I-35131 Padova INFN Sezione di Perugia I-06123 Perugia

From April to July 2018,a data sample at the peak energy of the T(4 S) resonance was collected with the Belle Ⅱ detector at the SuperKEKB electron-positron *** is the first data sample of the Belle Ⅱ *** Bhabha and digamma events,we measure the integrated luminosity of the data sample to be(496.3±0.3±3.0) pb-1,where the first uncertainty is statistical and the second is *** work provides a basis for future luminosity measurements at Belle Ⅱ.

关键词： luminosity Bhabha digamma Belle II

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Targeting menin: a promising therapeutic strategy for susceptible acute leukemia subtypes

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Signal Transduction and Targeted Therapy 2023年第11期8卷 5141-5142页

作者： pietro Di Fazio department of Visceral Thoracic and Vascular SurgeryPhilipps University of MarburgBaldingerstrasse35043MarburgGermany

Two recent studies published in Nature focused on the clinical efficacy of the menin inhibitor revumenib(SNDX-5613)in KMT2A(histone-lysine N-methyltransferase 2A)-rearranged or NPM1(Nucleophosmin1)-mutant acute myeloid leukemia.1,2 These studies indicate that menin inhibition and its acquired resistance to long-term exposure to revuminib are key points for future treatment,emphasizing the role of menin as a challenging and promising target for the current treatment of leukemia.

关键词： acute clinical therapeutic

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Characterizing the human-robot haptic dyad in robot therapy of stroke survivors

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International Journal of Intelligent Computing and Cybernetics 2014年第3期7卷 267-288页

作者： Dalia de Santis Jacopo Zenzeri Maura Casadio Lorenzo Masia Valentina Squeri pietro Morasso Robotics Brain and Cognitive Sciences DepartmentIstituto Italiano di TecnologiaGenoaItaly department of Informatics BioengineeringRobotics and Systems EngineeringUniversity of GenoaGenoaItaly Robotic Research Center Division of Mechatronics&DesignSchool of Mechanical&Aerospace EngineeringNanyang Technological UniversitySingaporeSingapore

Purpose–The working hypothesis,on which this paper is built,is that it is advantageous to look at protocols of robot rehabilitation in the general context of human-robot interaction in haptic *** purpose of this paper is to propose a new method to detect and evaluate an index of active participation(AC index),underlying the performance of robot-assisted *** is important for avoiding the slacking phenomenon that affects robot ***/methodology/approach–The evaluation of the AC index is based on a novel technique of assistance which does not use constant or elastic forces but trains of small force impulses,with amplitude adapted to the level of impairment and a frequency of 2 Hz,which is suggested by recent results in the field of intermittent motor control.A preliminary feasibility test of the proposed method was carried out during a haptic reaching task in the absence of visual feedback,for a group of five stroke patients and an equal group of healthy ***–The AC index appears to be stable and sensitive to training in both populations of ***/value–The main original element of this study is the proposal of the new AC index of voluntary control associated with the new method of pulsed haptic interaction.

关键词： Human-robot haptic interaction Robot therapy Stroke survivors

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Comparison Between deep Learning Models and Traditional Machine Learning Approaches for Facial Expression Recognition in Ageing Adults

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Journal of Computer Science & Technology 2020年第5期35卷 1127-1146页

作者： Andrea Caroppo Alessandro Leone pietro Siciliano Institute for Microelectronics and Microsystems National Research Council of ItalyLecce 73100Italy

Facial expression recognition is one'of the most active areas of research in computer vision since one of the non-verbal communication methods by which one understands the lnood/mental state of a person is the expression of ***,it has been used in various fields such as human-robot interaction,security,computer graphics animation,and ambient ***,it remains a challenging task since existing approaches lack generalizability and almost all studies ignore the effects of facial attributes,such as *** expression recognition even though the research indicates that facial expression inanifestation varies with ***,a lot of progress has been made in this topic and great improvements in classification task were achieved with the emergence of deep learning *** approaches have sliown how hierarchies of features can be directly learned from original data,thus avoiding classical hand designed feature extraction methods that generally rely on manual operations witli labelled ***,research papers systematically exploring tlu4 performance of existing.deep architectures for the task of classifying expression of ageing adults are absent in the *** the present work a tentative to try this gap is done considering the performance of three recent deep convolutiorial neural networks models(Vgg-16,AlexNet and googLeNet/Inception V1)and evaluating it on four different benchmark datcisets(FACES,Lifespan,CIFE,and FER2013)which also contain facial expressions performed by elderly *** the baseline,and with the aim of making a comparison,two traditional inacliine learning approaches based on handcrafted features extraction process are evaluated on the same *** out an exhaustive and rigorous experimentation focused on the concept of "transfer learning",which consists of replacing the output level of the deep architectures considered with new output levels appropriate to the number of classes(facial expressions),

关键词： computer vision deep learning facial expression machine learning ageing adult

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Messages from Powdery Mildew DNA:How the Interplay with a Host Moulds Pathogen genomes

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Journal of Integrative Agriculture 2014年第2期13卷 233-236页

作者： pietro D Spanu department of Life Sciences Imperial College LondonLondon SW7 2AZUnited Kingdom

The genomes of the barley, Arabidopsis and pea powdery mildew are significantly larger than those of related fungi. This is due to an extraordinary expansion of retro-trasposons that are evident as repetitive elements in the sequence. The protein coding genes are fewer than expected due to an overall reduction in the size of gene families, a reduction in the number of paralogs and because of the loss of certain metabolic pathways. Many of these changes have also been observed in the genomes of other taxonomically unrelated obligate biotrophic pathogens. The only group of genes that bucks the trend of gene loss, are those encoding small secreted proteins that bear the hall marks of effectors.

关键词： barley powdery mildew genome effectors

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Editorial on "Role of thermal ablation in the management of colorectal liver metastasis"

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Hepatobiliary Surgery and Nutrition 2020年第1期9卷 62-64页

作者： Antonio giorgio pietro gatti Massimo de Luca Paolo Matteucci Valentina giorgio Liver Unit and Interventional Ultrasound Unit Athena Clinical InstitutePiedimonte Matese(CE)Italy Internal Medicine Unit Brindisi General HospitalBrindisiItaly Liver Unit Cardarelli HospitalNaplesItaly Radiation Oncology Unit Campus BiomedicoRomaItaly Fondazione Policlinico A.gemelli IRCCS Department of Woman and Child Health and Public HealthRomaItaly

The last 30 years have shown the increasing role of Ablation in the treatment of malignant liver tumors. By the introduction of percutaneous ethanol injection (PEI) as first ablation tool for percutaneous treatment of hepatocellular carcinoma (HCC) in cirrhosis that firstly showed very high efficacy (1), several ablation techniques (mainly thermal) have been introduced in clinical practice aimed at destroying primary and secondary hepatic tumors as alternative or substitute tools to surgery. Radiofrequency ablation (RFA) was the first thermal technique that showed a good efficacy to ablate liver metastases (2). Among the secondary liver tumors, colorectal liver metastases (CRLM) represent the unique indication for ablation (2). Unlike HCC in cirrhosis where the role of RFA is well defined as first line therapy for HCC nodules gery in 1-3 HCC nodules with the maximum diametergm. Liver resection remains the standard of care for CRLM and the indications to ablation remain confined to nonresectable patients (4). The review article by Takahashi and Berber recently published in HBSN wells illustrates the current role of ablation in treatment of CRLM (5).

关键词： colorectal metastasis surgery

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