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Italian survey on non-steroidal anti-inflammatory drugsand gastrointestinal bleeding in children

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World Journal of gastroenterology 2016年第5期22卷 1877-1883页

作者： Sabrina Cardile Massimo Martinelli Arrigo Barabino Paolo gandullia Salvatore Oliva giovanni Di Nardo Luigi Dall'Oglio Francesca Rea gian Luigi de'angelis Barbara Bizzarri graziella guariso Enzo Masci Annamaria Staiano Erasmo Miele Claudio Romano gastroenterology and Endoscopic Unit Department of PediatricsUniversity of Messina98100 MessinaItaly department of Translational Medical Science Section of PediatricsUniversity of Naples“Federico II”80131 NaplesItaly department of Pediatric gastroenterology Gaslini Institute16148 GenoaItaly department of Pediatrics and Infantile Neuropsychiatry Pediatric Gastroenterology and Liver UnitSapienza University of Rome00185 RomeItaly Digestive Surgery and Endoscopy Unit Bambino GesùChildren’s Hospital00165 RomeItaly gastroenterology and Endoscopy Service University of Parma43126 ParmaItaly Unit of Paediatric gastroenterology Digestive EndoscopyHepatologyand Care of Children with Liver TransplantationDepartment of Women’s and Children’s HealthUniversity Hospital of Padova35128 PadovaItaly gastrointestinal Endoscopy Azienda Ospedaliera San Paolo University HospitalUniversity of Milan20142 MilanItaly

AIM: To investigate gastrointestinal complications associated with non-steroidal anti-inflammatory drug(NSAIDs) use in ***: A retrospective, multicenter study was conducted between January 2005 and January 2013, with the participation of 8 Italian pediatric gastroenterology centers. We collected all the cases of patients who refer to emergency room for suspected gastrointestinal bleeding following NSAIDs consumption, and underwent endoscopic evaluation. Previous medical history, associated risk factors, symptoms and signs at presentation, diagnostic procedures, severity of bleeding and management of gastrointestinal bleeding were collected. In addition, data regarding type of drug used, indication, dose, duration of treatment and prescriber(physician or selfmedication) were examined. RESULTS: Fifty-one patients, including 34 males, were enrolled(median age: 7.8 years). Ibuprofen was the most used NSAID [35/51 patients(68.6%)]. Pain was the most frequent indication for NSAIDs use [29/51 patients(56.9%)]. Seven patients had positive family history of Helicobacter pylori(H. pylori) infection or peptic ulcer, and 12 had associated comorbidities. Twenty-four(47%) out of 51 patients used medication inappropriately. Hematemesis was the most frequent symptom(33.3%). Upper gastrointestinal endoscopy revealed gastric lesions in 32/51(62%) patients, duodenal lesions in 17(33%) and esophageal lesions in 8(15%). In 10/51(19.6%) patients, a diagnosis of H. pylori gastritis was made. Forty-eight(94%) patients underwent medical therapy, with spontaneous bleeding resolution, while in 3/51(6%) patients, an endoscopic hemostasis was ***: The data collected in this study confirms that adverse events with the involvement of the gastrointestinal tract secondary to NSAID use are also common in

关键词： Hematemesis gastrointestinal bleeding non-steroidal anti-inflammatory drug Melena Pediatrics

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双奇核184Au中新转动带的发现（英文）

IMP & HIRFL Annual Report 2011年 33-34页

作者：李仕成 g. de angelis N. Marginean A. g.dea D. R. Napoli M. Axiotis C. Rusu T. Martinez Istituto Nazionale di Fisica Nucleare Laboratori Nazionali di Legnaro 2. Hahn-Meitner-Institut

High-spin states in doubly odd 184Au have been populated via the 159Tb(29Si, 4n) reaction. The 29Si beam at an energy of 140 MeV was provided by the accelerator complex of the Tandem-XTU and ALPI at the Laboratori Nazionali di Legnaro, Italy. The target was an enriched 159Tb metallic foil of 2 mg/cm2 thickness backed with a 5 mg/cm2 thickness Au layer. In-beam

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Causes and manifestations of chylothorax in children

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Pediatric Investigation 2018年第3期2卷 203-203页

作者： Carlo Bellini Laura Costanza de angelis Tommaso Bellini Luca Antonio Ramenghi department Mother and Child Neonatal Intensive Care UnitGaslini InstituteGenoaItaly

To the editor:We read with great interest the excellent article by guo et al1 describing causes and manifestations of chylothorax in children in *** are few points of the article we would like to *** authors affirmed that finding seven cases affected by congenital lymphatic malformations was *** is not clear if seven cases were considered as a low or high incidence ***,congenital chylothorax of the newborn may be linked to congenital thoracic duct defects,isolated or associated with generalized lymphatic vessel dysplasia,which is the more likely cause;more rarely,congenital chylothorax is the result of trauma at birth,malignancies,thrombosis of the superior vena cava or subclavian vein causing high central venous pressure.

关键词： Causes manifestations chylothorax

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划地为牢

领导文萃 2000年第10期 109-109页

作者： de angelis

以色列是一个非常独特的国家。自1948年建国以来,处于阿拉伯国家包围之中的以色列一直处于战争状态,至今已逾五十年。以色列在美国的纵容下,奉行扩张政策,不断蚕食阿拉伯领土,双方战事不断。以色列这种以邻为壑的政策既给阿拉伯人民带... 详细信息

以色列是一个非常独特的国家。自1948年建国以来,处于阿拉伯国家包围之中的以色列一直处于战争状态,至今已逾五十年。以色列在美国的纵容下,奉行扩张政策,不断蚕食阿拉伯领土,双方战事不断。以色列这种以邻为壑的政策既给阿拉伯人民带来沉重的苦

关键词：以色列阿拉伯

Signature Inversion in πi13/2 ■ vi13/2 Band of 184Au

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IMP & HIRFL Annual Report 2004年 70-70页

作者： g. de angelis,N. Marginean,A. g.dea,D. R. Napoli,M. Axiotis,C. Rusu,T. Martinez Istituto Nazionale di Fisisca Nucleate Laboratori Nazionale di Legnaro Legnaro Italy Istituto Nazionale di Fisisca Nucleate Laboratori Nazionale di Legnaro Legnaro Italy Istituto Nazionale di Fisisca Nucleate Laboratori Nazionale di Legnaro Legnaro Italy Hahn-Meitner-Institut Berlin germany Istituto Nazionale di Fisisca Nucleare Laboratori Nazionale di Legnaro Legnaro Italy Istituto Nazionale di Fisisca Nucleare Laboratori Nazionale di Legnaro Legnaro Italy Istituto Nazionale di Fisisca Nucleare Laboratori Nazionale di Legnaro Legnaro Italy

Low-spin signature inversion has been systematically observed throughout the chart of nuclides in the πg9/2(■) vg9/2, πh11/2(■)vh11/2, πh11/2(■)vh13/2, and πh9/2(■) vi13/2, configurations. Considering the high-j nature of these configurations, we have tried to find the similar signature inversion phenomenon in the πi13/2 (■) vi13/2, bands in

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Identification of Oblate Band in Odd-odd 184Au

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IMP & HIRFL Annual Report 2004年 71-71页

作者： g. de angelis,N. Marginean,A. g.dea,D. R. Napoli,M. Axiotis,C. Rusu,T. Martinez Istituto Nazionale di Fisisca Nucleare Laboratori Nazionale di Legnaro Legnaro Italy Hahn-Meitner-Institut Berlin germany Istituto Nazionale di Fisisca Nucleare Laboratori Nazionale di Legnaro Legnaro Italy Istituto Nazionale di Fisisca Nucleare Laboratori Nazionale di Legnaro Legnaro Italy Istituto Nazionale di Fisisca Nucleare Laboratori Nazionale di Legnaro Legnaro Italy Istituto Nazionale di Fisisca Nucleare Laboratori Nazionale di Legnaro Legnaro Italy Istituto Nazionale di Fisisca Nucleare Laboratori Nazionale di Legnaro Legnaro Italy

The high-spin states in 184Au were populated by using the 159Tb( 29Si, 4ng) 184Au reaction at a bombarding energy of 140 MeV. The 29Si beam of 8 pnA was provided by the accelerator complex of the Tandem-XTU and ALPI a...

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Experimental Study of High-Spin Band Structures of 183Au

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IMP & HIRFL Annual Report 2004年 69-69页

作者： g. de angelis,N. Marginean,A. g.dea,D. R. Napoli,M. Axiotis,C. Rusu,T. Martinez Istituto Nazionale di Fisisca Nuclear Laboratori Nazionali di Legnaro Italy Istituto Nazionale di Fisisca Nuclear Laboratori Nazionali di Legnaro Italy Istituto Nazionale di Fisisca Nuclear Laboratori Nazionali di Legnaro Italy Istituto Nazionale di Fisisca Nuclear Laboratori Nazionali di Legnaro Italy Istituto Nazionale di Fisisca Nuclear Laboratori Nazionali di Legnaro Italy Istituto Nazionale di Fisisca Nuclear Laboratori Nazionali di Legnaro Italy Istituto Nazionale di Fisisca Nuclear Laboratori Nazionali di Legnaro Italy

High-spin states in 183Au have been studied experimentally by using the 159Tb(29Si, 5n)183Au reaction at a beam energy of 140 MeV. The 29Si beam of 8 pnA was provided by the accelerator complex of the Tandem-XTU and ALPI at the Laroratori Nazionali di Legnero, Italy, and focussed onto a natural metallic 159Tb foil of 2

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ConservativeapproachinPeutz-JeghersSyndrome:Single-balloon enteroscopyandsmallbowelpolypectomy

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World Journal of gastrointestinal Endoscopy 2014年第7期6卷 318-323页

作者： Torroni F Romeo E Rea F de angelis P Foschia F Faraci S Federici di Abriola g Contini AC Caldaro T Dall’Oglio L Filippo Torroni Erminia Romeo Francesca Rea Paola De Angelis Francesca Foschia Simona Faraci Giovanni Federici di Abriola Anna Chiara Contini Tamara Caldaro Luigi Dall’Oglio Department of Surgery and Transplantation Digestive Surgery and Endoscopy Unit Bambino Gesù Children’s Hospital IRCCS 00165 Rome Italy

AIM: To assess the usefulness of the balloon assisted enteroscopy in preventing surgical intervention in pa-tients with Peutz-Jeghers syndrome (PJS) having a small bowel large polyps. METHODS: Seven consecutive asymptomatic pts(age 15-38 years) with PJS have been collected; six under-went polypectomy using single balloon enteroscopy(Olympus SIF Q180) with antegrade approach using push and pull technique. SBE system consists of the SIF-Q180 enteroscope, an overtube balloon control unit(OBCU Olympus Balloon Control Unit) and a dispos-able silicone splinting tube with balloon(ST-SB1). All procedures were performed under general anesthesia. Previously all pts received wireless capsule endos-copy(WCE). Prophylactic polypectomy was reservedmainly in pts who had polyps > 15 mm in diameter. The balloon is inflated and deflated by a balloon control unit with a safety pressure setting range from-6.0 kPa to +5.4 kPa. Informed consent has been obtained from pts or parents for each ***: Six pts underwent polypectomy of small bowel polyps; in 5 pts a large polyp > 15 mm(range 20-50 mm in diameter) was resected; in 1 patient with WCE negative, SBE was performed for previous surgi-cal resection of gastrointestinal stromal tumors. In 2 pts endoscopic clips were placed due to a polypectomy. No surgical complication have been reported. SBE with resection of small bowel large polyps in PJS pts was useful to avoid gastrointestinal bleeding and emergency laparotomy due to intestinal intussuscep-tions. No gastrointestinal tumors were found in sub-sequent enteroscopic surveillance in all seven pts. In order surveillance, all pts received WCE, upper en-doscopy, ileocolonoscopy every 2 years. No pts had extraintestinal malignant lesions. SBE was performed when WCE was positive for significant polyps(> 15 mm).CONCLUSION: The effective of prophylactic polyp-ectomy of small bowel large polyps(> 15 mm) could be the first line treatment for conservative approach in management of PJS

关键词： Peutz-Jeghers 症候群汽球帮助了 enteroscopy Polypectomy

Innovative surgical approaches for hepatocellular carcinoma

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World Journal of Hepatology 2016年第13期8卷 591-596页

作者： Riccardo Memeo Nicola de’angelis Vito de Blasi Zineb Cherkaoui Oronzo Brunetti Vito Longo Tullio Piardi Daniele Sommacale Jacques Marescaux Didier Mutter Patrick Pessaux department of Digestive Surgery University Hospital of Strasbourg IRCAD Research Institute Against Cancer of the Digestive Tract IHU-Strasbourg Institute for Image-Guided Surgery Inserm U1110 Institutde Recherche sur les Maladies Virales et Hépatiques Unit of Digestive Hepato-Pancreato-Biliary Surgery and Liver Transplantation Henri Mondor Hospital AP-HP Université Paris-Est Val de Marne UPEC Medical Oncology Unit Cancer institute"Giovanni Paolo II" Medical Oncology Unit Hospital "Di Miccoli" Service de Chirurgie générale Digestive et Endocrinienne Hopital Robert Debré Centre Hospitalier Universitaire de Reims Université de Reims Champagne-Ardenne

Hepatocellular carcinoma(HCC)is the sixth most common cancer worldwide,with an increasing diffusion in Europe and the United *** management of such a cancer is continuously progressing and the objective of this paper is to evaluate innovation in the surgical treatment of *** this review,we will analyze the modern concept of preoperative management,the role of laparoscopic and robotic surgery,the intraoperative use of three dimensional models and augmented reality,as well as the potential application of fluorescence.

关键词： Hepatocellular carcinoma Liver resection Hepatectomy New prespectives Innovative surgical approaches