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2019-2022年某三甲骨科医院骨科住院患者医院感染监测数据与趋势

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中华医院感染学杂志 2024年第8期34卷 1196-1200页

作者：蔡磊芮永军糜菁熠王秋波葛新无锡市第九人民医院/无锡市骨科医院医院感染管理科江苏无锡214121

目的探讨2019-2022年无锡市骨科医院骨科住院患者的医院感染现况。方法通过病历管理平台及医院感染实时监测系统,分析2019-2022年骨科住院患者的医院感染情况,骨科各科室的医院感染情况,骨科住院患者的感染部位分布情况,主要感染病原菌... 详细信息

目的探讨2019-2022年无锡市骨科医院骨科住院患者的医院感染现况。方法通过病历管理平台及医院感染实时监测系统,分析2019-2022年骨科住院患者的医院感染情况,骨科各科室的医院感染情况,骨科住院患者的感染部位分布情况,主要感染病原菌的分布情况及主要病原菌的耐药情况。结果2019-2022年骨科住院患者共68792例,发生医院感染1072例,医院感染率为1.56%;医院感染1161例次,例次感染率为1.69%;与2019年比较,2020-2022年骨科住院患者医院感染率及例次感染率均降低,且2020年、2022年医院感染率及例次感染率均低于2021年(P<0.05);2019-2022年骨科科室医院感染及例次感染最高的前三位分别为手外二科、创伤骨科、足踝外科;2019-2022年骨科住院患者感染部位最常见的前三位分别为手术部位、皮肤软组织、下呼吸道;革兰阴性菌以大肠埃希菌、鲍氏不动杆菌占比最高,而革兰阳性菌以金黄色葡萄球菌、表皮葡萄球菌占比最高;大肠埃希菌对氨苄西林、哌拉西林、头孢呋辛的耐药率较高,而鲍氏不动杆菌对头孢呋辛、头孢唑林、头孢他啶耐药率较高;金黄色葡萄球菌对头孢西丁、青霉素、克林霉素的耐药率较高,而对万古霉素、替考拉宁均敏感;表皮葡萄球菌对红霉素、头孢西丁、青霉素、苯唑西林、克林霉素的耐药率较高,而对万古霉素敏感。结论医院应针对骨科各科室、主要感染部位、主要感染病原菌及主要病原菌的耐药情况采取及时有效的预防和控制对策,以降低骨科住院患者的医院感染情况。

关键词：骨科住院患者医院感染感染分布病原菌耐药性

功能性电刺激联合核心肌群训练对脑卒中偏瘫患者下肢功能和血清Aβ与Tau的影响

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川北医学院学报 2024年第4期39卷 524-527页

作者：邱锦芳郭峰林军厦门大学附属中山医院干部保健科福建厦门361000

目的:探讨在核心肌群训练基础上对脑卒中偏瘫患者予以功能性电刺激(FES)治疗对下肢功能恢复的影响。方法:按治疗方式不同,将96例脑卒中偏瘫患者分为对照组(n=48)与观察组(n=48),两组均进行常规治疗。对照组予以核心肌群训练;观察组予以... 详细信息

目的:探讨在核心肌群训练基础上对脑卒中偏瘫患者予以功能性电刺激(FES)治疗对下肢功能恢复的影响。方法:按治疗方式不同,将96例脑卒中偏瘫患者分为对照组(n=48)与观察组(n=48),两组均进行常规治疗。对照组予以核心肌群训练;观察组予以FES治疗联合核心肌群训练,两组均治疗4周。于治疗前后比较两组下肢运动功能[简化Fugl-Meyer下肢运动功能量表(FMA-LE)]、平衡功能[Berg平衡量表(BBS)]、步行功能[功能性步行能力分级(FAC)、10 m步行时间测试(10MWT)、6 min步行距离测试(6MWT)]、日常生活能力[改良Barthel指数(MBI)]和神经功能[美国国立卫生研究院卒中量表(NHISS)]的评定,并进行血清β-淀粉样蛋白(Aβ)、Tau蛋白水平的测定。结果:治疗后,观察组患者FMA-LE评分和BBS评分高于对照组(P<0.05),6MWT和FAC分级高于对照组(P<0.05);10MWT低于对照组(P<0.05),MBI评分高于对照组(P<0.05);NHISS评分低于对照组(P<0.05)。治疗后,观察组血清Aβ、Tau水平低于对照组(P<0.05)。结论:FES联合核心肌群训练能够改善脑卒中偏瘫患者下肢运动功能、平衡功能和步行能力,降低血清Aβ、Tau水平,疗效显著。

关键词：脑卒中下肢运动功能步行能力核心肌群训练功能性电刺激

Influence of Noises on Remote State Preparation Using g.z.State

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Communications in Theoretical Physics 2008年第9期50卷 643-647页

作者： LIANg Hua-qiu LIU Jin-Ming State Key Laboratory of Precision Spectroscopy Department of Physics East China Normal University Shanghai 200062 China Department of Physics Taizhou University Linhai 317000 China

Using a quantum channel consisting of a g.z.state exposed to noisy environment,we investigate how toremotely prepare an entangled state and a qubit state,*** solving the master equation in the Lindbladform,the influence of the various types of noises on the g.z.state is first *** we use the fidelity to describehow close the remotely prepared state and the initial state *** results show that the fidelity is a function of thedecoherence rates and the angles of the initial *** is found that for each of the two RSP schemes,the influence ofthe noise acting simultaneously in x,y,and z directions on the average fidelity is the strongest while the influence of thenoise acting in x or z direction on the average fidelity is relatively weaker.

关键词： remote state preparation fidelity g.z.state noisy environment

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正流量液压挖掘机平整微操作抖动问题分析

液压气动与密封 2024年第5期44卷 10-13页

作者：冯涛嵇秋池王飞徐州徐工挖掘机械有限公司江苏徐州221001 中国矿业大学机电工程学院江苏徐州221001

针对某型正流量液压挖掘机平整微操作抖动问题进行控制原理分析,建立动臂提升和斗杆内收两复合微操作性能数学模型。搭建试验平台,从液压、振动和噪声角度评估动臂提升和斗杆内收两复合冲击抖动性能。当出现压力抖动时,动臂提升先导压... 详细信息

针对某型正流量液压挖掘机平整微操作抖动问题进行控制原理分析,建立动臂提升和斗杆内收两复合微操作性能数学模型。搭建试验平台,从液压、振动和噪声角度评估动臂提升和斗杆内收两复合冲击抖动性能。当出现压力抖动时,动臂提升先导压力稳定在1.721~1.751 MPa之间,斗杆内收先导压力变化范围较大,在1.423~1.675 MPa之间,故动臂提升与斗杆内收微操作出现压力抖动与斗杆内收先导压力变化密切相关。但司机位置处未表现出较强的冲击抖动性,各悬置z向隔振率在21~25 dB之间,隔振性能较好;驾驶室声压级在74~78 dB之间,隔噪性能良好。此外,试验样机P7档位动臂提升时间为4.5 s,斗杆内收时间为2.5 s,动臂提升和斗杆内收两复合时间为3.2 s。当转速1650 r/min、扭矩负荷率72%时,平整效率试验值为520次/h,平整油耗试验值为28.30 L/h,平整经济性较优。

关键词：正流量数学模型试验冲击抖动

水电站生态调度操作门机动力学分析与安全性评价

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三峡大学学报（自然科学版） 2024年第1期46卷 99-105页

作者：方子帆赵爽邱名岱周益周宇张宇三峡大学机械与动力学院湖北宜昌443002 中国长江电力股份有限公司溪洛渡水力发电厂云南昭通657300 水电机械设备设计与维护湖北省重点实验室(三峡大学) 湖北宜昌443002

水电站生态调度操作门机受到耦合动力学、欠驱动、作业环境等因素的影响,其结构的振动和有效载荷的摆动会产生结构破坏并影响整机稳定性与作业精度.基于模态综合法和有限元法分别建立带轨道的门架结构降阶模型和绳索结构有限元柔性体模... 详细信息

水电站生态调度操作门机受到耦合动力学、欠驱动、作业环境等因素的影响,其结构的振动和有效载荷的摆动会产生结构破坏并影响整机稳定性与作业精度.基于模态综合法和有限元法分别建立带轨道的门架结构降阶模型和绳索结构有限元柔性体模型,利用虚拟样机建模技术,搭建操作门机刚柔耦合动力学模型,分析了小车运行速度和加速度、起升重量、绳索摆长等参数对有效载荷摆动以及门架结构振动的影响.同时,选取结构性能指标和动力学性能指标,通过安全指标雷达图动态评价了操作门机的安全性.研究结果表明:小车运行速度和加速度对主梁水平位移的影响明显大于对垂直位移的影响;主梁的最大应力幅值与起升重量成正比;有效载荷的残余摆动和主梁的水平位移幅度范围正相关于绳索摆长的大小.操作门机动力学分析与安全性评价方法为这类门式起重机的使用与维护提供了参考.

关键词：操作门机虚拟样机技术结构动力学安全评价指标

A high-strength mineralized collagen bone scaffold for large-sized cranial bone defect repair in sheep

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Regenerative Biomaterials 2018年第5期5卷 283-292页

作者： Shuo Wang.z.ijun zhao Yongdong Yang Antonios g.Mikos zhiye qiu Tianxi Song Fuzhai Cui XiumeiWang Chunyang.z.ang State Key Laboratory of New Ceramics and Fine Processing Key Laboratory of Advanced Materials of Ministry of EducationSchool of Materials Science and EngineeringTsinghua UniversityBeijing 100084China Department of Neurosurgery The First Affiliated Hospital of Baotou Medical SchoolBaotou 014010China Dongzhimen Hospital Affiliated Beijing University of Chinese Medicine Beijing 100700China Department of Bioengineering Rice UniversityHoustonTX 77030USA Beijing Allgens Medical Science and Technology Co. Ltd.Beijing 100176China

Large-sized cranial bone defect repair presents a great challenge in the *** ideal cranioplasty materials to realize the functional and cosmetic recovery of the defect must have sufficient mechanical support,excellent biocompatibility,good osseointegration and biodegradability as *** this study,a high-strength mineralized collagen(MC)bone scaffold was developed with biomimetic composition,microstructure and mechanical properties for the repair of sheep largesized cranial bone defects in comparison with two traditional cranioplasty materials,polymethyl methacrylate and titanium *** compact MC scaffold showed no distinct pore structure and therefore possessed good mechanical *** strength and elastic modulus of the scaffold were much higher than those of natural cancellous bone and slightly lower than those of natural compact *** vitro cytocompatibility evaluation revealed that the human bone marrow mesenchymal stem cells(hBMSC)had good viability,attachment and proliferation on the compact MC scaffold indicating its excellent *** adult sheep cranial bone defect model was constructed to evaluate the performances of these cranioplasty materials in repairing the cranial bone *** results were investigated by gross observation,computed tomography scanning as well as histological *** in vivo evaluations indicated that compact MC scaffold showed notable osteoconductivity and osseointegration with surrounding cranial bone tissues by promoting bone *** results suggested that the compact MC scaffold has a promising potential for large-sized cranial bone defect repair.

关键词： mineralized collagen cranial bone defect bone regeneration sheep cranioplasty materials

Synthesis and Crystal Structure of a New Complex [CuL(Phen)]·NO_3

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Chinese Journal of Structural Chemistry 2006年第11期25卷 1343-1346页

作者： qiu Xiao-Hang.z.AO Jun TONg Xiao-Lan Department of Chemistry Nankai University Tianjin 300071 China

A new mononuclear copper（Ⅱ） complex [CuL（Phen）]-NO3 （L - 2-{2-[（3,5-dibro- mosalicylidene）amino]ethyl }- 1 H- 1,3-benzimidazole, Phen = 1,10-phenanthroline） has been synthesized and its crystal structure was determined by X-ray diffraction method. It crystallizes in monoclinic, space group C2/c with a = 24.966（7）, b = 15.673（4）, c = 16.600（5） A,β = 123.981（4）°, C28H20Br2CuN604, Mr = 727.86, V = 5386（2） A^3, z = 8, Dc = 1.795 g/cm^3,μ（MoKα = 3.826 mm^-1, F（000） = 2888, the final R = 0.0508 and wR = 0.1024 for 5440 independent reflections with Rint = 0.1134. The title compound is composed of [CuL（Phen）]＋ cation and NO3^- anion. The coordination geometry around copper atom is a highly distorted trigonal bipyramid consisting of one benzimidazole nitrogen atom, one phenolato oxygen atom and one phenanthroline nitrogen atom on the equatorial plane together with one imine nitrogen atom and one phenanthroline nitrogen atom occupying the axial positions. The hydrogen bonding and π-π stacking interactions link the copper complex molecules into a 3-D supramolecular structure.

关键词： crystal structure copper complex 1,10-phenanthroline hydrogen bonds

Full frequency-phase synchronization for physical-layer distributed clocks

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The Journal of China Universities of Posts and Telecommunications 2012年第3期19卷 68-73,113页

作者： gUO Wei zHENg Lin qiu Hong-bing School of Information and Communication Guilin University of Electronic TechnologyGuilin 541004China

In wireless networks, the majority of cooperative communications rely on the high-accuracy timing synchronization among isolated nodes. However, most presented physical-layer distributed synchronization algorithms so far cannot satisfy the requirement for real applications. To realize frequency and phase synchronization of distributed clocks, i.e., full synchronization, inspired by the character of the proportional plus integral controller that it may help an unstable system be a no steady-state error one, a new loop structure of distributed discrete phase-locked loop （PLL） is designed. Furthermore, by using algebraic graph theory, the convergence of this scheme is analyzed for both directed and undirected networks, and full synchronization is proved to be reached. Simulation results are given to corroborate the proposed algorithm and analysis.

关键词： cooperative communication wireless network distributed synchronization phase-locked loop

Reaction of o-Carboryne with Furans： Facile Synthesis of Carborane- Fused Oxanorbornenes and Their Derivatives

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Chinese Journal of Chemistry 2018年第4期36卷 273-279页

作者： Rongyizhang Yinggen Yuan zaozao qiu zuowei Xie Shanshai-Hong Kong Joint Laboratory in Chemical Synthesis Shanghai Institute of Organic Chemistry Chinese Academy of Sciences 345 Lingling Road Shanshai 200032 China Department of Chemistry The Chinese University of Hong Kong Shatin New Territories Hong Kong China

o-Carboryne （1,2-dehydro-o-carborane） is a very useful synthon for the synthesis of a variety of carborane-functionalized molecules. Diels-Alder reaction of o-carboryne with furans gave a series of carborane-fused oxanorbornenes in moderate to high yields using 1-OTf-1,2-C_2B_10H_11 as carboryne precursor. The resultant cycloadducts can undergo hydrogenation, cyclic oxidation, bromination, [4＋2]/[2＋2] cycloaddition and nucleophilic ring opening reaction to afford a variety of highly functionalized carboranes that may find applications as useful basic units in medicine and materials science.

关键词： carborane carboryne [4+2] cycloaddition furan ring opening reaction