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Non-SMC condensin Ⅰ complex subunit D2 and non-SMC condensin Ⅱ complex subunit D3 induces inflammation via the IKK/NF-κB pathway in ulcerative colitis

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World Journal of gastroenterology 2019年第47期25卷 6813-6822页

作者： Chang-Wen yuan Xue-Liang Sun Li-Chao Qiao Hai-Xia Xu Ping Zhu Hong-jin Chen Bo-Lin yang Department of Neurology Jiangsu Province Hospital of Chinese MedicineAffiliated Hospital of Nanjing University of Chinese MedicineNanjing 210029Jiangsu ProvinceChina First Clinical Medical College Nanjing University of Chinese MedicineNanjing 210029Jiangsu ProvinceChina Department of Colorectal Surgery Jiangsu Province Hospital of Chinese MedicineAffiliated Hospital of Nanjing University of Chinese MedicineNanjing 210029Jiangsu ProvinceChina

BACKgROUND Ulcerative colitis(UC)is a chronic,nonspecific intestinal inflammatory disease with undefined ***-SMC condensin I complex subunit D2(NCAPD2)and non-SMC condensin II complex subunit D3(NCAPD3)play pivotal roles in chromosome assembly and segregation during both mitosis and *** date,there has been no relevant report about the functional role of NCAPD2 and NCAPD3 in *** To determine the level of NCAPD2/3 in intestinal mucosa and explore the mechanisms of NCAPD2/3 in *** Levels of NCAPD2/3 in intestinal tissue were detected in 30 UC patients and 30 healthy individuals with in situ hybridization(ISH).In vitro,NCM60 cells were divided into the NC group,model group,si-NCAPD2 group,si-NCAPD3 group and si-NCAPD2+si-NCAPD3 *** cytokines were measured by ELISA,IKK and NF-κB were evaluated by western blot,and IKK nucleation and NF-κB volume were analyzed by immunofluorescence *** Compared with expression in healthy individuals,NCAPD2 and NCAPD3 expression in intestinal tissue was significantly upregulated(Pgroup,IL-1β,IL-6 and TNF-αin the si-NCAPD2,si-NCAPD3 and si-NCAPD2+si-NCAPD3 groups were significantly downregulated(Pgroups was significantly decreased(Pghly expressed in the intestinal mucosa of patients with active *** of NCAPD2/3 promotes the release of pro-inflammatory cytokines by modulating the IKK/NF-κB signaling pathway.

关键词： Non-SMC condensin I complex subunit D2 Non-SMC condensin Ⅱ complex subunit D3 Ulcerative colitis Inflammation IKK/NF-κB Pathway

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Effect of multilayer CrN/CrAlN coating on the corrosion and contact resistance behavior of 316L SS bipolar plate for high temperature proton exchange membrane fuel cell

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Journal of Materials Science & Technology 2022年第2期97卷 134-146页

作者： S.Pugal Mani P.Agilan M.Kalaiarasan K.Ravichandran N.Rajendran y.Meng Department of Analytical Chemistry University of MadrasChennai-25India Department of Chemistry Anna UniversityChennai-25India State Key Laboratory of Tribology Tsinghua UniversityBeijing 100084China

Stainless steels have received wide attention as a substitute material for bipolar plates in high temperature proton exchange membrane fuel cell(HT-PEMFC).In the present work,the CrN,CrAlN and multilayer CrN/CrAlN coatings were deposited on 316 L SS to increase the corrosion resistance and decrease the interfacial contact *** deposited coatings exhibited face centered cubic phase structure and it was verified from the X-ray diffraction pattern.X-ray photo electron spectroscopy results showed the formation of both CrN and CrAlN layers on 316 L ***/CrAlN coating is more helpful in water management due to low surface roughness and high contact angle in the HT-PEMFC *** corrosion resistance behavior of all the samples were studied in 85%H_(3)PO_(4)solution at 140℃purged with H_(2)(HT-PEMFC anode)and O_(2)(HT-PEMFC cathode)*** results showed that all the coatings considerably improved the performance of 316 L SS and superior corrosion resistance was observed for CrN/CrAlN multilayer coating,whose protective efficiency was 98.12%and 96.14%in the two simulated HT-PEMFC *** results of electrochemical impedance spectroscopic studies demonstrated higher impedance for CrN/CrAlN *** morphological studies performed after corrosion studies revealed that protection ability of CrN/CrAlN coating still remained acceptable.A very low interfacial contact resistance value of 6 mΩ cm^(2) at 140 N/cm;was observed for CrN/CrAlN ***,after corrosion studies,the interfacial contact resistance value of CrN/CrAlN coated 316 L was much lower than that of CrN and CrAlN coatings due to the increased oxidation *** maximum power density of about 0.93 W/cm^(2) at 2 A/cm^(2) and output voltage of 0.96 V was observed for CrN/CrAlN coating.

关键词： Bipolar plate 316L SS Corrosion Contact resistance Contact angle Surface roughness

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Synthesis and optimization of high surface area mesoporous date palm fiber-based nanostructured powder activated carbon for aluminum removal

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Chinese Journal of Chemical Engineering 2021年第4期34卷 472-484页

作者： Alfarooq O.Basheer Marlia M.Hanafiah Mohammed Abdulhakim Alsaadi y.Al-Douri Abbas A.Al-Raad Department of Earth Sciences and Environment Faculty of Science and TechnologyUniversiti Kebangsaan Malaysia43600 BangiSelangorMalaysia Centre for Tropical Climate Change System Institute of Climate ChangeUniversiti Kebangsaan MalaysiaBangi 43600SelangorMalaysia Nanotechnology and Catalysis Research Center(NANOCAT) University of Malaya50603 Kuala LumpurMalaysia National Chair of Materials Science and Metallurgy University ofNizwa611 NizawaOman University Research Center Cihan University SulaimaniyaSulaymaniyah 46002Iraq Department of Mechatronics Engineering Faculty of Engineering and Natural SciencesBahcesehir University34349 BesiktasIstanbulTurkey

Date palm fiber(DPF)derived from agrowaste was utilized as a new precursor for the optimized synthesis of a costeffective,nanostructured,powderactivated carbon(nPAC)for aluminum(Al3+)removal from aqueous solutions using carbonization,KOH activation,response surface methodology(RSM)and central composite design(CCD).The optimum synthesis condition,activation temperature,time and impregnation ratio were found to be 650℃,1.09 hour and 1:1,***,the optimum conditions for removal were 99.5%and 9.958 mgg 1 in regard to uptake *** optimum conditions of nPAC was analyzed and characterized using XRD,FTIR,FESEM,BET,TgA and Zeta ***,the adsorption of the Al3+conditions was optimized with an integrated RSMCCD experimental *** results revealed that the adsorption kinetics data was well fitted by the pseudosecond order model,whereas the adsorption isotherm data was best represented by the Freundlich isotherm *** activated carbon indicated that DPF can serve as a costeffective precursor adsorbent for Al^(3+)removal.

关键词： Agricultural waste Nanocomposites Wastewater treatment Industrial applications

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半群OF_n(y)的幂等元秩

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数学的实践与认识 2018年第12期48卷 247-253页

作者：金云娥赵平贵州师范大学数学科学学院

设OT（Xn）是Xn={1,2,…,n}上的保序变换半群.y是Xn的非空真子集且｜y｜=r,令OT（Xn,y）={α∈OT（Xn）：Xnα y},OF（Xn,y）={α∈OT（Xn,y）：Xnα=yα}.考虑半群OFn（y）={α∈OF（Xn,y）：｜im（α）｜≤r-1},证明了半群OFn（y）是... 详细信息

设OT（Xn）是Xn={1,2,…,n}上的保序变换半群.y是Xn的非空真子集且｜y｜=r,令OT（Xn,y）={α∈OT（Xn）：Xnα y},OF（Xn,y）={α∈OT（Xn,y）：Xnα=yα}.考虑半群OFn（y）={α∈OF（Xn,y）：｜im（α）｜≤r-1},证明了半群OFn（y）是由幂等元生成,并得到了OFn（y）的幂等元秩.

关键词：保序全变换半群幂等元秩

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gyroscopic modes decoupling method in parametric instability analysis of gyroscopic systems

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Acta Mechanica Sinica 2018年第5期34卷 963-969页

作者： y.J.Qian X.D.yang H.Wu W.Zhang T.Z.yang College of Mechanical Engineering Beijing University of TechnologyBeijing 100124China Department of Mechanics Tianjing UniversityTianjing 300072China

Traditional procedures to treat vibrations of gyroscopic continua involve direct application of perturbation methods to a system with both a strong gyroscopic term and other weakly coupled *** this study,a gyroscopic modes decoupling method is used to obtain an equivalent system with decoupled gyroscopic modes having only weak *** the axially moving string as an example,the instability boundaries in the vicinity of parametric resonances are detected using both the traditional coupled gyroscopic system and our system with decoupled gyroscopic modes,and the results are compared to show the advantages and disadvantages of each method.

关键词： Axially moving material Decoupling of gyroscopic modes Parametric instability Perturbation method gyroscopic system

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Mechanism of olfactory deficit in neurotrauma and its related affective distress: A narrative review

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World Journal of Psychiatry 2021年第12期11卷 1259-1266页

作者： Mark Logan Siddharth Kapoor Luke Peterson Martin Oliveira Dong y Han Department of Neurology UK HealthCareLexingtonKY 40536United States Department of Neurology University of KentuckyLexingtonKY 40536United States Department of Psychology University of ConnecticutStorrsCT 06269United States Department of Neuropsychology Neuro Health of ConnecticutWest HartfordCT 06107United States

Traumatic brain injury(TBI)is among the leading causes of death and disability all over the *** is also commonly associated with clinical sequelae of posttraumatic depression,and reports of other subsequent affective distress are ***,posttraumatic changes in chemoreceptive sensory functions,primarily due to coup-contrecoup injury induced shearing of the olfactory nerve fibers,leading to anosmia and ageusia are also well documented in the ***,the current literature is limited in addressing the intersections between said *** aim of this study was to provide a focused narrative review of the literature,to address these intersections found in clinical sequelae of *** chemoreceptive sensory deficits are also linked to significant affective distress of their own,this review addresses the bidirectionality between sensory deficit and affective ***,demographics,mechanisms,and clinical implications are *** research is presented and discussed,in an effort to highlight the importance of consideration for all factors in TBI patient care and future research.

关键词： Brain injuries Brain injuries,traumatic Anosmia Depression Affective symptoms Smell

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农作物传播视角下的欧亚大陆史前东西方文化交流

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中国科学：地球科学 2017年第6期47卷 530-543页

作者：董广辉杨谊时韩建业王辉陈发虎兰州大学西部环境教育部重点实验室、兰州大学资源环境学院兰州730000 中国人民大学历史学院.北京100872 甘肃省文物考古研究所兰州730000

欧亚大陆东西方文化交流的历史是广受关注的科学问题,考古证据显示至少可追溯至青铜时代早期,但具体的时间和路线并不清楚.文化交流过程伴随着农作物的传播与交换,相对于考古遗物,农作物遗存鉴定标准明确且可精确定年,是研究文化交流过... 详细信息

欧亚大陆东西方文化交流的历史是广受关注的科学问题,考古证据显示至少可追溯至青铜时代早期,但具体的时间和路线并不清楚.文化交流过程伴随着农作物的传播与交换,相对于考古遗物,农作物遗存鉴定标准明确且可精确定年,是研究文化交流过程的理想材料.本文总结和对比了欧亚大陆史前遗址的植物大遗存鉴定和直接测年数据,以及人骨碳同位素分析结果,系统梳理了东亚起源的农作物粟黍西传,西亚起源的农作物小麦和大麦东传,及其相互汇聚的时空过程.结合其他考古材料,探讨史前欧亚大陆东西方文化交流的过程.结果显示,约10500a BP起源于西亚地区的小麦和大麦在8000a BP之前传入欧洲和中亚西部,4500~4000a BP传入中亚东部和中国西北地区.粟黍在7700a BP之前驯化于中国北方,4500~4000a BP传入中亚东部,3500a BP后传入西亚和欧洲.约4400a BP在中亚东部的哈萨克斯坦地区出现黍和小麦、大麦同时利用的迹象,可能是东西方文化元素最早汇聚的地区.4500~3500a BP粟黍和麦类作物混合利用的现象主要出现在中亚东部和中国西北地区,其后扩散至欧亚大陆的东西两侧.上述研究暗示跨大陆东西方文化交流可能始于距今5千纪,在青铜时代得到强化,为汉代的丝绸之路的开凿奠定了重要的基础.

关键词：新石器-青铜时代欧亚大陆农作物传播食物全球化跨大陆文化交流

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Effects　of　iron　on　growth,degree　of　pigmentization　and　nitrogen　assimilation　in　Skeletonema　costatum

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Acta Oceanologica Sinica 1998年第2期17卷 187-196页

作者： Zheng A. Chen C. Zhou C. Chen y. Department of Oceanography Xiamen University Xiamen 361005 China

Ｅｆｆｅｃｔｓｏｆｉｒｏｎｏｎｇｒｏｗｔｈ，ｄｅｇｒｅｅｏｆｐｉｇｍｅｎｔｉｚａｔｉｏｎａｎｄｎｉｔｒｏｇｅｎａｓｓｉｍｉｌａｔｉｏｎｉｎＳｋｅｌｅｔｏｎｅｍａｃｏｓｔａｔｕｍＺｈｅｎｇＡｉｒｏｎｇ，ＣｈｅｎＣｉｍｅ... 详细信息

Ｅｆｆｅｃｔｓｏｆｉｒｏｎｏｎｇｒｏｗｔｈ，ｄｅｇｒｅｅｏｆｐｉｇｍｅｎｔｉｚａｔｉｏｎａｎｄｎｉｔｒｏｇｅｎａｓｓｉｍｉｌａｔｉｏｎｉｎＳｋｅｌｅｔｏｎｅｍａｃｏｓｔａｔｕｍＺｈｅｎｇＡｉｒｏｎｇ，ＣｈｅｎＣｉｍｅｉ，ＺｈｏｕＣｉｙｏｕ，ＣｈｅｎＹ...

关键词： Effects growth,degree Skeletonema and costatum nitrogen pigmentization

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Variability in the composition and export of silica in the Huanghe River Basin

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Science China Earth Sciences 2015年第7期58卷 2078-2089页

作者： RAN XiangBin CHE Hong ZANg Jiaye yU yonggui LIU Sen ZHENg LiLi Research Center for Marine Ecology First Institute of OceanographyState Oceanic Administration Key Laboratory of Marine Chemistry Theory and Technology Ministry of Education Ocean University of China Key Laboratory of Marine Sedimentology and Environmental geology The First Institute of OceanographyState Oceanic Administration College of Environmental and Civil Engineering Chengdu University of Technology

Concentrations of suspended particle material(SPM), dissolved silicate(DSi), biogenic silica(BSi), phytoliths(plant produced siliceous microscopic structures), and other parameters were analyzed to examine the influence of both natural processes and human activities on silica delivery to the estuary of the Huanghe River(yellow River). Our results indicate that the concentrations of DSi in the river decreased significantly since 1986. Approximately 34% of dissolved silica was trapped in the basin between 1986 and 2010 due to a reduction of soil erosion. Phytoliths comprised 67.2%–96.3% of BSi, with the smoothing bar type being the dominant form. Concentrations of BSi are significantly higher in the Huanghe River compared to other major rivers throughout the world due to its high sediment yield. We also found that the ratios of BSi/(BSi+DSi) and BSi/SPM were approximately 0.5 and 0.003 at Lijin near the river mouth, indicating that BSi carried in suspension by the Huanghe River was an important component of the rivers silica load. Significant amounts of BSi were also composed of phytoliths in Bohai Sea sediments near the Huanghe River estuary with the smoothing bar form again being the most abundant. The relatively high specific fluxes of BSi in the Huanghe River reflect its high turbidity and high erosion rates in the basin. The high sediment load originating on the Loess Plateau is likely responsible for the higher BSi flux, in agreement with a general trend of increasing BSi flux with increasing sediment flux in global river systems. This study demonstrates that BSi transported by rivers can be composed largely of phytoliths originating from the erosion of topsoils. The flux of phytoliths in river's suspended sediment load may therefore represent a significant contribution to the biogeochemical cycle of silica in coastal waters.

关键词： phytolith biogenic silica dissolved silicate suspended particle material Huanghe River (yellow River)

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Metal-free multicomponent polymerization of activated diyne,electrophilic styrene and isocyanide towards highly substituted and functional poly(cyclopentadiene)

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Science China Chemistry 2023年第3期66卷 863-869页

作者： Xinyue Liu Xueqin yang Xin Li Jianwei Sun Benzhao He Jacky W.y.Lam Ben Zhong Tang Department of Chemistry and Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction Guangdong-Hong Kong-Macao Joint Laboratory of Optoelectronic and Magnetic Functional MaterialsThe Hong Kong University of Science and TechnologyHong Kong 999077China Center for Advanced Materials Research Beijing Normal University at ZhuhaiZhuhai 519085China School of Science and Engineering Shenzhen Institute of Aggregate Science and TechnologyThe Chinese University of Hong KongShenzhen 518172China Center for Aggregation-Induced Emission South China University of TechnologyGuangzhou 510640China

The development of a facile and efficient polymerization to prepare cyclopentadiene-containing polymers is of vital importance and highly desired. In this work, a metal-free multicomponent polymerization of activated diyne, electrophilic styrene and isocyanide for the preparation of highly substituted poly(cyclopentadiene) was established. Soluble and thermally stable polymers with high molecular weights are obtained in high yields under mild conditions. By introducing the tetraphenylethene or triphenylamine moiety into polymer backbones, the resultant polymers show unique aggregation-induced emission(AIE)characteristics. Interestingly, AIE polymers can also be generated in situ from non-AIE monomers. Moreover, the prepared polymers can generate photopatterns to function as photoresists and can also serve as visualizing agents to selectively stain the lipid droplets in live cells. This efficient polymerization will open up enormous opportunities for preparing functional cyclopentadiene-containing polymers applicable in diverse areas.

关键词： multicomponent polymerization activated alkynes highly substituted poly(cyclopentadiene)

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