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Transactions of Tianjin University 2010年第3期16卷 235-238页

作者：曹红宝 BESIO walter g JONES Steven 周鹏 Department of Biomedical Engineering Latech University Department of Biomedical Engineering University of Rhode Island School of Precision Instrument and Opto-Electronics Engineering Tianjin University

In electroencephalogram (EEg) modeling techniques, data segment selection is the first and still an important step. The influence of a set of data-segment-related parameters on feature extraction and classification in an EEg-based brain-computer interface (BCI) was studied. An auto search algorithm was developed to study four datasegment-related parameters in each trial of 12 subjects’ EEg. The length of data segment (LDS), the start position of data (SPD) segment, AR order, and number of trials (NT) were used to build the model. The study showed that, compared with the classification ratio (CR) without parameter selection, the CR was increased by 20% to 30% with proper selection of these data-segment-related parameters, and the optimum parameter values were subject-dependent. This suggests that the data-segment-related parameters should be individualized when building models for BCI.

关键词： data segment parameter selection EEg classification brain-computer interface (BCI)

Propagation Characteristics of Damped Traveling wave in a One-Dimensional Marginal Sea Ice

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wuhan University Journal of Natural Sciences 2015年第1期20卷 79-86页

作者： XIE Tao FANg He Perrie w CHEN wei HE Yijun School of Marine Sciences Nanjing University of Information Science and Technology Bedford Institute of Oceanography Dartmouth B2Y 4A2NS Canada School of Automation Wuhan University of Technology

Based on the wave velocity potential of sea water and marginal sea ice, a modified formula about damped traveling wave is proposed. From this formula, it is obvious that the propagation characteristics of ocean wave in marginal sea ice are affected by ice thickness, temperature, salinity and ice growth rate. Attenuation coefficient approaches a limit value of 0.99 when ice thickness increases in the range of 0.5-50 m. when ice temperature increases in the range from 18 ℃ to 3 ℃, attenuation coeffi- cient slowly decreases, while it rapidly decreases when ice temperatures is above a critical ice temperature of 3 ℃. Both attenuation coefficient and wavelengths of damped traveling wave nearly increase linearly with the increase of ice salinity and ice growth rate.

关键词： marginal sea ice wave-ice interactions attenuation coefficient wave propagation

Biobehavioral assessment of the anxiety disorders:Current progress and future directions

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world Journal of Psychiatry 2017年第3期7卷 133-147页

作者： Deah Abbott Yasmin Shirali J Kyle Haws Caleb w Lack Department of Psychology University of Central Oklahoma

It is difficult to accurately assess and differentially diagnose the anxiety *** current system of assessment relies heavily on the subjective measures of client self-report,clinical observation,and clinical ***,recent technological advances may enable practitioners to utilize objective,biobehavioral measures of assessment in a clinical *** current body of literature on two of these biobehavioral tools(eyetracking and electrocardiogram devices) is promising,but more validation and standardization research is needed to maximize the utility of these ***-tracking devices are uniquely capable of providing data that can be used to differentially diagnose anxiety disorders from both other commonly comorbid and misdiagnosed *** eye-tracking and electrocardiogram devices are able to provide change-sensitive assessment *** objective,real-time feedback can assist clinicians and researchers in assessing treatment efficacy and symptom *** developed wearable and highly portable electrocardiogram devices,like the wearable fitness and behavior tracking devices used by many consumers,may be particularly suited for providing this feedback to *** these biobehavioral devices would supply an objective,dimensional component to the current categorical diagnostic assessment *** posit that if adequate funding and attention are directed at this area of research,it could revolutionize diagnostic and on-going assessment practices and,in doing so,bring the field of diagnosis out of the 20 th century.

关键词： Biobehavioral Assessment Diagnosis Anxiety Electrocardiogram Electrocardiogram Eyetracker

Finding chemopreventatives to reduce amyloid beta in yeast

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Neural Regeneration Research 2016年第2期11卷 244-245页

作者： Ian g.Macreadie Costa Arvanitis Prashant Bharadwaj School of Science and Health Innovations Research Institute RMIT University Centre of Excellence for Alzheimer’s disease Research and Care School of Medical Sciences Edith Cowan University CHIRI Biosciences Research Precinct School of Biomedical Sciences Curtin University

Alzheimer’s disease（AD）is the most common form of age-related dementia with the latest report（world Alzheimer Report,2015）showing 46.8 million people are currently affected by *** number is expected to double every 20 years unless there is effective therapeutic *** 42 amino acid peptide known as amyloid beta（or Aβ）has been implicated as one of the main causative agents of AD after its discovery in plaques in 1985（Masters et al.,1985）.

关键词： Finding chemopreventatives to reduce amyloid beta in yeast AD

Self Healing Asphalt Concrete-state of the Art

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武汉理工大学学报 2010年第17期32卷 67-70,88页

作者： JIANg H wU S P QIU J wEI w Key Laboratory of Silicate Materials Science and Engineering Wuhan University of TechnologyWuhan 430070China Delft University of Technology P.O. Box 50482600 GA Delftthe Netherlands

Similar to engineering materials used in civil engineering,aerospace engineering and other applications,an asphalt concrete also suffers from fatigue cracking due to a cyclic loading conditions on the road,which results in a decrease of the stiffness and the strength. The self healing capability has been investigated widely due to its unique contribution to the recovery of the stiffness and the strength from cracking and then to extend the service life of asphalt pavements. In this paper,general concepts of self healing and self healing asphalt concrete were introduced. Then,the parameters that influence the self healing capability of the asphalt binder and asphalt concrete were discussed. Inspired from other self healing materials,the possibilities of applying microcapsule self healing system in asphalt concrete were investigated in detail.

关键词： self-healing asphalt asphalt concrete microcapsules

getting out of energy-intensive and“dirty”transport for sustainable societies

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The Innovation 2022年第6期3卷 29-30页

作者： Becky P.Y.Loo Kay w.Axhausen Department of geography University of Hong KongHong Kong SAR 999077China School of geography and Environment Jiangxi Normal UniversityJiangxi 330022China IVT ETH Z€urichZ€urichSwitzerland

INTRODUCTION Societies around the world have committed themselves to achieving the Paris goals of carbon dioxide(CO_(2))reduction and limiting global warming to 1.5Cwith different levels of legal *** transport sector is both a major use of energy and amajor source of air pollutants,including CO_(2),nitrogen oxides,ozone,particularmatter,and volatile organic compounds that cause climate change and harm human health.1,2 The recent Ukraine–Russia war triggered countries to evaluate a fossil–fuel-dependent transport system that is highly vulnerable.

关键词： transport legal ozone

The transgression record of the gucheng Lake in 9.6 ka B. P.

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Chinese Science Bulletin 1997年第17期42卷 1459-1461页

作者： Shen, J wang, SM Liu, SY Zhang, g Nanjing Institute of geography & Limnology Chinese Academy of Sciences Nanjing China Southeast University Nanjing China guangzhou Institute of geochemistry Chinese Academy of Sciences Guangzhou China

THE gucheng Lake is located in gaochun County, Jiangsu Province, China (31°14′36'—31°19′28'N, 118°51′34'—118°57′56'E). It lies in the southeast monsoon climate area. To study the pateoclimatic and environmental change of the lake area since Late Ice Age and clarify evolution of the southeast monsoon, a core of 20 m (gS1) was drilled at the center of

关键词： gucheng Lake sedimental core transgression record.

STRUCTURAL STUDIES ON AgAR FRACTIONS EXTRACTED SEQUENTIALLY FROM CHINESE RED SEAwEEDS:gRACILARIA SJEOSTEDTII, g. TEXTORII AND g. SALICORNIA USINg13C-NMR AND IR SPECTROSCOPY

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Journal of Oceanology and Limnology 1988年第2期6卷 87-103页

作者：纪明侯 M.Lahaye w.Yaphe Institute of Occanology Academia Sinica Qingdao Dept of Microbiology & Immunology Mcgill University Montreal Canada CanadaM. Lahaye and w. Yaphe(Dept of Microbiology & Immunology Mcgill University Montreal Canada)

The polysaccharides of three species of Chinese gracilaria (Rhodophyta) were extracted by sequential solvent extraction and the chemical structures of the fractions obtained were investigated by using 13C-NMR and IR *** 13C-NMR spectra showed that the main extract, cold water fraction, from g. sjeostedtii consisted of repeating disaccharides of agarobiose and (1→3)-β-D-galactopyranosy 1-(1→4)-α-L-galactopyranose 6-sulfate, the latter being a precursor to agarobiose and converted to agarobiose after alkali modification. The component of the 60% ethanol fraction from g. textorii was composed mainly of agarose 6-sulfate, 6-O-methyl-agarose and some amount of agarose, whose structures remained unchanged after alkali treatment. The autoclave extract from g. salicornia revealed a complex structure composed of 6-0-methyl-agarose, 2-0-methyl-agarose, branched 4-0-methyl-L-galactose and agarose 4-sulfate, All the substiluents in these agaroses, were stable against alkali treatment. The alkali ex

关键词： NMR TEXTORII AND g C-NMR AND IR SPECTROSCOPY SALICORNIA USINg STRUCTURAL STUDIES ON AgAR FRACTIONS EXTRACTED SEQUENTIALLY FROM CHINESE RED SEAwEEDS IR

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Nucleotide sequence conservation of novel and established cis-regulatory sites within the tyrosine hydroxylase gene promoter

1990年

作者： B.w.·利夫菲克(Blaise w. Liffick)

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Frontiers in Biology 2015年第1期10卷 74-90页

作者： Meng wANg Kasturi BANERJEE Harriet BAKER John w. CAVE Burke Medical Research Institute White Plains NY 10605 USA weill Cornell Medical College Brain and Mind Research Institute NY 10065 USA

Tyrosine hydroxylase （TH） is the rate-limiting enzyme in catecholamine biosynthesis and its gene proximal promoter （〈 1 kb upstream from the transcription start site） is essential for regulating transcription in both the developing and adult nervous systems. Several putative regulatory elements within the TH proximal promoter have been reported, but evolutionary conservation of these dements has not been thoroughly investigated. Since many vertebrate species are used to model development, function and disorders of human catecholaminergic neurons, identifying evolutionarily conserved transcription regulatory mechanisms is a high priority. In this study, we align TH proximal promoter nucleotide sequences from several vertebrate species to identify evolutionarUy conserved motifs. This analysis identified three elements （a TATA box, cyclic AMP response element （CRE） and a 5＇-ggTgg-3＇ site） that constitute the core of an ancient vertebrate TH promoter. Focusing on only eutherian mammals, two regions of high conservation within the proximal promoter were identified： a -250 bp region adjacent to the transcription start site and a -85 bp region located approximately 350 bp further upstream. within both regions, conservation of previously reported cis-regulatory motifs and human single nucleotide variants was evaluated. Transcription reporter assays in a TH-expressing cell line demonstrated the functionality of highly conserved motifs in the proximal promoter regions and electromobility shift assays showed that brain-region specific complexes assemble on these motifs. These studies also identified a non-canonical CRE binding （CREB） protein recognition element in the proximal promoter. Together, these studies provide a detailed analysis of evolutionary conservation within the TH promoter and identify potential cisregulatory motifs that underlie a core set of regulatory mechanisms in mammals.

关键词： catecholamine dopamine transcription evolution