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3T腓动脉非增强MR血管成像:个体间比较3D血流依赖减影MRA和2D非血流依赖非减影MRA

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国际医学放射学杂志 2017年第1期 116-117页

作者： g.knobloch M.T.Lauff S.Hirsch C.Schwenke B.Hamm M.Wagner 屈瑾 Department of Radiology Charité-Universit?tsmedizin BerlinCharité Campus Mitte

摘要目的比较3 T 3D血流依赖减影MRA和2D非血流依赖非减影MRA对腓动脉的评估。方法 42例外周动脉闭塞病人,行腓动脉非增强MRA,采用3 T MRA(快速自旋

关键词： MRA 流依赖腓动脉 MR 减影

低剂量对比剂在大螺距双源CT冠状动脉血管成像中的应用

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国际医学放射学杂志 2014年第2期 186-186页

作者： A.Lembcke C.Schwenke P.A.Hein g.knobloch T.Durmus B.Hamm 朱红 Department of Radiology Charité - University Medicine BerlinCampus Charité Mitte Charitéplatz 1 10117 BerlinGermany

目的评估大螺距双源CT冠状动脉成像检查中使用较低剂量对比剂对于影像质量的影响。方法前瞻性选择连续100例行双源CT冠状动脉成像检查的病人[体质量65~

关键词：心电门控成像技术对比剂冠状动脉血管造影冠状动脉疾病多层CT

激光诱导热疗(LITT):小型电极的评价和在1.0 T高场开放MRI下对猪肝模型的应用

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国际医学放射学杂志 2011年第1期34卷 92-页

作者： F.Streitparth g.knobloch D.Balmert S.Chopra J.Rump U.Wonneberger 程悦 Department of Radiology Charité Humboldt-Universitt zu Berlin

目的评价在1.0T高场开放MRI中一种新型的LITT电极进行肝恶性肿瘤热消融的可行性和安全性。方法带有封闭冷却循环的小型6F双管保护导管。

关键词：激光诱导热疗(LITT) 热消融肝恶性肿瘤

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磁敏感加权成像诊断肩袖钙化性肌腱炎

国际医学放射学杂志 2016年第2期 193-193页

作者： D.Nrenberg H.U.Ebersberger T.Walter B.Ockert g.knobloch g.Diederichs 綦述晓 Department of Radiology Charité-University Medicine Berlin Division of Imaging Sciences and Biomedical Engineering King’s College London

摘要目的评价磁敏感加权成像(SWI)和标准肩关节MR序列对肩袖钙化性肌腱炎病人的诊断性能,并与常规X线检查比较两者鉴别钙化灶的能力。材料与方法机构伦理委员会批准了本项前瞻性研究。所有病人获得书面知情同意。54例病人临床怀疑有肩... 详细信息

摘要目的评价磁敏感加权成像(SWI)和标准肩关节MR序列对肩袖钙化性肌腱炎病人的诊断性能,并与常规X线检查比较两者鉴别钙化灶的能力。材料与方法机构伦理委员会批准了本项前瞻性研究。所有病人获得书面知情同意。54例病人临床怀疑有肩袖钙化性肌腱炎。X线摄影(参考标准)显示,27例阳性钙化灶,27例无阳性钙化灶。所有病例

关键词：钙化性肌腱炎病人序列肩袖磁敏感加权成像钙化灶

FinFETs based on layered 2D semiconductors

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Science China Materials 2023年第9期66卷 3759-3760页

作者： Theresia knobloch Tibor grasser Institute for Microelectronics TUWienGusshausstrasse 27-291040 ViennaAustria

Over the past decades, the continued scaling of transistor dimensions, as dictated by Moore’s Law, has reduced energy consumption and increased the computational power of integrated circuits. At gate lengths below 12 nm, the scaling meets a physical limit, and as for ensuring reasonable gate control, a further reduction of the gate lengths requires scaling of the silicon thickness.

关键词： scaling transistor layered

State of the Art Treatment of Non-Ferrous Castings 3-in-l Heat Treatment Systems Combine Foundry Processes

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材料热处理学报 2004年第5期25卷 552-554页

作者： Volker R. knobloch CEC - Consolidated Engineering Co. Inc.

The interior of a high-pressure die-casting is of an unsatisfactory quality. Engine blocks made with this die casting process show lower specific engine performance. Pressure die-casting can hardly be heat treated for obvious reasons. PSM (Precision Sand Molds) process uses sand and organic binder to generate a mold and even allows the manufacturing of complex diesel engine blocks in aluminum alloys. Combined technologies are available for semi-permanent mold castings with cores and castings made in Precision Sand Molds with organic binders. Castings are placed into the special heat treatment furnace immediately after pouring without the operations in stand alone machinery. This patented Sand Lion 3- in-1 technology processes hot castings and carries out three (3) foundry processes simultaneously in one (1) automated machine: 1) De-coring and sand removal; 2) Thermal sand reclamation; 3) Solution heat treatment of castings. The combination of several main casting processes is reflected in significant reductions of energy consumption, of production costs, and improving the quality of the castings. Audits in foundries using the 3-in-l process showed an average reduction in production costs of more than 30%.

关键词：沙模固溶热处理集成铸造流化床

Metabolic control of adult neural stem cell behavior

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Frontiers in Biology 2015年第2期10卷 100-106页

作者： Marlen knobloch Sebastian Jessberger Brain Research Institute Faculty of Medicine and Science University of Zurich 8057 Zurich Switzerland

Neural stem cells generate new neurons throughout life in distinct regions of the mammalian brain. This process, called adult neurogenesis, is important for tissue homeostasis and physiological brain function. In addition, failing or altered neurogenesis has been associated with a number of diseases such as major depression and epilepsy. Thus, understanding the molecular mechanisms governing the neurogenic process in the adult brain may enable future therapeutic approaches to target neural stem/progenitor cells （NSPCs） and their progeny to ameliorate disease symptoms and/or disease progression. Recently, the control of cellular metabolism has emerged as a regulator of NSPC activity in the adult brain. Here we review recent findings that attempt to describe stage-specific modulations of metabolism to ensure proper neurogenesis and suggest future avenues of research aiming to understand how metabolism affects NSPC behavior.

关键词： adult neurogenesis metabolic switch quiescence proliferation differentiation

Mathesis Perennis: Mathematics in Ancient, Renaissance, and Modern Times

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自然科学史研究 2005年第B7期24卷 10-22页

作者： Eberhard knobloch Techinal University of Berlin Germany

Approaching Antiquity: Archimedes and the Fields MedalSince 1936 the so-called Fields Medal “is awarded every four years on the occasion of the International Congress of Mathematicians to recognize outstanding achievement for existing work and for the promise of future achievement” (http://***/medals/Fields/***).It replaces the non-existing Nobel prize for mathematicians. Up until 2005 it has been awarded 44 times.

关键词：数学研究诺贝尔奖国际会议学术交流

Surgical approach affecting long-term urinary continence status after robot-assisted laparoscopic prostatectomy prospectively evaluated using self-reported functional status(Expanded Prostate Cancer Index Composite,EPIC-26)

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Current Urology 2024年第1期18卷 61-65页

作者： Mathias Reichert Ame Strauß Joost Wilhelm Voß Hans Christoph von knobloch Hannah Maria Neuenhofer Annemarie Uhlig Lutz Trojan Mirjam Naomi Mohr Department of Urology University Medical CenterGoettingenGermany Department of Pediatrics University HospitalBonnGermany

Purpose:The aim of the study was to examine the influence of the surgical approach for robot-assisted laparoscopic prostatectomy(RALP)on long-term urinary continence status in the era of self-reported functional status measures using the Expanded Prostate Cancer Index Composite *** and methods:This is a prospective evaluation of 232 patients undergoing RALP between September,2019 and September,*** continence status and postoperative incontinence(pad usage)were evaluated 12 months after RALP using Expanded Prostate Cancer Index Composite 26 *** were categorized according to their surgical approach and outcome into the following groups:successful nerve sparing(NS),primarily without nerve sparing(***),and no nerve sparing by secondary resection(NNS by SR).The median levels of their questionnaire outcomes were evaluated and compared using the Wilcoxon rank sum test with continuity ***:Urinary continence status 12 months after RALP differed significantly between the NS and ***(p=0.0071)and the NS and NNS by SR(p=0.0076)*** was no significant difference between the *** and NNS by SR(p=0.53)*** usage 12 months after RALP had no significant difference with regard to SR of the neurovascular bundle(p=0.14).Conclusions:Patient-reported outcomes of long-term urinary continence status seem to show no difference in postoperative continence,regardless of whether a non-nerve-sparing result was planned or reached through ***,preservation of neurovascular bundle seems to lead to better long-term continence rates.

关键词： Prostate cancer Robot-assisted radical prostatectomy Expanded Prostate Cancer Index Composite 26 Urinary incontinence Surgical approach Nerve sparing