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A Structured Method of Teaching Epidural Block reduces the incidence of accidental dural puncture in inexperienced trainees.

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Open Journal of Anesthesiology 2024年第4期14卷 131-135页

作者： Marco Scorzoni gianluigi gonnella Emanuele Capogna Marina Campione gaetano Draisci Matteo Velardo giorgio Capogna Department of Anesthesiology Fondazione Policlinico Gemelli IRCCS Rome Italy Department of Economics and Law Enna Kore University Enna Italy European School of Obstetric Anesthesia Rome Italy

Background: The rate of accidental dural puncture is particularly high during the period of training, especially in novices. The structured epidural teaching model (SETM) includes three standardized video lessons, the construction of a 3D epidural module by trainees and practical training by using an epidural simulator with and without the CompuFlo™ Epidural instrument. In this study we report the retrospective analysis of the accidental dural puncture rate of inexperienced trainees during their 6 months clinical practice rotation in obstetrics before and after the introduction of the SETM in our Institution. Method: We evaluated the incidence of accidental dural puncture before the introduction of the SETM methodology and afterwards by analyzing our departmental database from February 2019 to January 2023. All epidural blocks were executed by trainees who had never previously performed an epidural block and were about to begin their obstetrics rotation. Results: We analyzed 7415 epidurals: 3703 were performed before the introduction of the SETM methodology (control group) and 3712 afterwards (study group). The incidence of accidental dural puncture was 0.37% for the control group and 0.13% for the study group (pg an accidental dural puncture was 64% (OR: 0.36) lower for trainees who had the training than for those who did not. Conclusions: After the introduction of the structured teaching method, we observed a significant reduction of accidental dural puncture during the training period. We hope that our observation will encourage a constructive discussion among experts about the need to use standardized and validated tools as a valuable aid in teaching epidural anesthesia.

关键词： teaching epidural Anesthesia obstetrical Anesthesia Anesthesia

A Lattice Boltzmann Study of Phase Separation in Liquid-Vapor Systems with gravity

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Communications in Computational Physics 2010年第2期7卷 350-361页

作者： Artur Cristea giuseppe gonnella Antonio Lamura Victor Sofonea Center for Fundamental and Advanced Technical Research Romanian AcademyBd.Mihai Viteazul 24300223 Timi¸soaraRomania Dipartimento di Fisica Universita di Bari and INFNSezione di BariVia Amendola 17370126 BariItaly Istituto Applicazioni Calcolo CNRVia Amendola 122/D70126 BariItaly

Phase separation of a two-dimensional van der Waals fluid subject to a grav-itational force is studied by numerical simulations based on lattice Boltzmann methodsimplemented with a finite difference scheme. A growth e... 详细信息

关键词： Lattice Boltzmann phase separation liquid-vapor gravity

NA48和NA62实验在π~0衰变中寻找暗光子（英文）

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中国科学技术大学学报 2016年第7期46卷 594-600,624页

作者： gonnella Francesco 无意大利国家核物理研究院弗拉斯卡蒂国家实验室意大利弗拉斯卡蒂00044 NA48/2合作组

2003到2004年间,CERN的NA48/2实验收集了1.69×107个完全重建的π0-→γe+e事例,动量范围在mee>10 Me V/c2,本底污染可忽略.该样本通过分析衰变链π0→γA',A'→e+e-来寻找暗光子.然而并没有观测到信号,本文给出暗光子质量mA'和混合参数... 详细信息

2003到2004年间,CERN的NA48/2实验收集了1.69×107个完全重建的π0-→γe+e事例,动量范围在mee>10 Me V/c2,本底污染可忽略.该样本通过分析衰变链π0→γA',A'→e+e-来寻找暗光子.然而并没有观测到信号,本文给出暗光子质量mA'和混合参数2的排除限.

关键词：暗光子 NA48 NA62

Financial Statement Valuations in Italian Accounting Thought Between the 19th and the 20th Century： From ＂Exchange Value＂ to ＂Historical Cost＂

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Journal of Modern Accounting and Auditing 2012年第9期8卷 1255-1271页

作者： Enrico gonnella University of Pisa Pisa Italy

The main subject of this paper is the theory of financial statement valuations observed in its historical development. More notably, regarding the subject, the research is concerned with some theoretical concepts developed by the Italian doctrine in a very specific age, namely, between the 19th and the 20th century, which in fact, devoid of any accounting regulation. This paper analyzes in particular the shift from the exchange value rule to the historical cost method and tries to explain the reasons of such a development. In the second half of the 19th century, some of the best Italian scholars, who were faced with the need to properly develop the problem of accounting valuations, thought that it was appropriate to rely on concepts that belonged to similar sciences, such as economics and real estate appraisal, by blindly borrowing the theory of value from the former and the theory of valuations from the latter. During that age, everything hinged around the concept of exchange value. At the dawn of the 20th century, the Italian accounting doctrine began to wonder about a subject that was crucial to the financial statement theory: the informative purposes underlying the financial statements. At the same time, the first principle took shape, which might be called as the "finalistic principle of value". It is still the basis of the theory of financial accounting measurements, for which different evaluative criteria must be applied to different informative purposes. Thus, an alternative criterion to that of the exchange value makes its appearance on the scene of the accounting valuations, notably the historical cost. The introduction of the historical cost criteria and above all the relinquishment of the combination of the "economic cost" in favor of that of the "manufacturing cost" allow the Italian accounting to get rid of the theories of economics and real estate appraisal, thus, becoming independent regarding the financial statement valuations.

关键词：财务报表会计原则意大利成本法估值价值历史房地产估价

Eye Movement Modeling Examples as a Teaching Tool for Epidural Block

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Open Journal of Anesthesiology 2023年第4期13卷 75-84页

作者： Emanuele Capogna Marco Scorzoni gian Luigi gonnella Matteo Velardo Pier Paolo giurì Mariano Ciancia gaetano Draisci giorgio Capogna European School of Obstetric Anesthesia (EESOA) Roma Italy Department of Anesthesiology Catholic University Medical School-Fondazione Policlinico Gemelli IRCCS Roma Italy

Introduction: Video examples with task demonstrations by experts, with the expert’s eye movements superimposed on the task, are known as “eye movement modeling examples” (EMME). We performed this study to evaluate if there were improvements in the performance of anesthesia novice trainees when executing the epidural technique after an EMME of epidural block procedure. Methods: We developed an eye movement modeling example (EMME) from eye tracking recordings made by experienced anesthesiologists with more than 20 years of experience. Forty-two PgY3 anesthesia trainees who had never previously performed an epidural block were randomized to receive (study group) or not receive (control group) the EMME video before their institutional training. All the trainees were evaluated every 10 epidural blocks until the end of the rotation period, by an independent, blinded observer using the global Rating Scale for Epidural Anesthesia (gRS). Results: Trainees who received the EMME training exhibited more respect for the patient’s tissues (P Discussion: This is the first study that has used the EMME for a practical, clinical teaching purpose on real patients and that has used it as an aid in teaching epidural anesthesia. We demonstrated that inexperienced trainees who received the EMME training improved their proficiency at epidural blocks as compared to those who had no EMME training beforehand. given this result, we welcome further studies to investigate the impact and the role of EMME on clinical teaching in the field of anesthesia.

关键词： Eye Tracking Eye Movement Modeling Example Epidural Anesthesia

Italian Accounting of the Late 19th Century and the Early 20th Century on the Epistemological Problem of Connections With Related Sciences

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Journal of Modern Accounting and Auditing 2012年第8期8卷 1095-1125页

作者： Enrico gonnella Lucia Talarico University of Pisa Pisa Italy

Leaf nutrient content and transcriptomic analyses of endive (Cichorium endivia) stressed by downpour-induced waterlog reveal a gene network regulating kestose and inulin contents

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Horticulture Research 2021年第1期8卷 1386-1401页

作者： giulio Testone Anatoly Petrovich Sobolev giovanni Mele Chiara Nicolodi Maria gonnella giuseppe Arnesi Tiziano Biancari Donato giannino Institute for Biological Systems National Research Council(CNR)Via Salaria Km 29300-00015 MonterotondoRomeItaly Institute of Sciences of Food Production CNR.Via G.Amendola 122/O-70126BariItaly Enza Zaden Italia Strada Statale Aurelia km.96.400–01016 TarquiniaViterboItaly

Endive(Cichorium endivia L.),a vegetable consumed as fresh or packaged salads,is mostly cultivated outdoors and known to be sensitive to waterlogging in terms of yield and quality.Phenotypic,metabolic and transcriptomic analyses were used to study variations in curly-(‘Domari’,‘Myrna’)and smooth-leafed(‘Flester’,‘Confiance’)cultivars grown in short-term waterlog due to rainfall excess before harvest.After recording loss of head weights in all cultivars(6-35%),which was minimal in‘Flester’,NMR untargeted profiling revealed variations as influenced by genotype,environment and interactions,and included drop of total carbohydrates(6–50%)and polyols(3–37%),gain of organic acids(2–30%)and phenylpropanoids(98–560%),and cultivar-specific fluctuations of amino acids(−37 to+15%).The analysis of differentially expressed genes showed gO term enrichment consistent with waterlog stress and included the carbohydrate metabolic process.The loss of sucrose,kestose and inulin recurred in all cultivars and the sucrose-inulin route was investigated by covering over 50 genes of sucrose branch and key inulin synthesis(fructosyltransferases)and catabolism(fructan exohydrolases)genes.The lowered expression of a sucrose gene subset together with that of SUCROSE:SUCROSE-1-FRUCTOSYLTRANSFERASE(1-SST)may have accounted for sucrose and kestose contents drop in the leaves of waterlogged plants.Two anti-correlated modules harbouring candidate hub-genes,including 1-SST,were identified by weighted gene correlation network analysis,and proposed to control positively and negatively kestose levels.In silico analysis further pointed at transcription factors of gATA,DOF,WRKY types as putative regulators of 1-SST.

关键词： process. weights subset

Performance and calibration of quark/gluon-jet taggers using 140 fb^(-1) of pp collisions at √s=13 TeV with the ATLAS detector

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Chinese Physics C 2024年第2期48卷 1-25页

作者： g. Aad B. Abbott K. Abeling N.J. Abicht S.H. Abidi A. Aboulhorma H. Abramowicz H. Abreu Y. Abulaiti B.S. Acharya C. Adam Bourdarios L. Adamczyk S.V. Addepalli M.J. Addison J. Adelman A. Adiguzel T. Adye A.A. Affolder Y. Afik M.N. Agaras J. Agarwala A. Aggarwal C. Agheorghiesei A. Ahmad F. Ahmadov W.S. Ahmed S. Ahuja X. Ai g. Aielli A. Aikot M. Ait Tamlihat B. Aitbenchikh I. Aizenberg M. Akbiyik T.P.A. Åkesson A.V. Akimov D. Akiyama N.N. Akolkar K. Al Khoury g.L. Alberghi J. Albert P. Albicocco g.L. Albouy S. Alderweireldt M. Aleksa I.N. Aleksandrov C. Alexa T. Alexopoulos F. Alfonsi M. Algren M. Alhroob B. Ali H.M.J. Ali S. Ali S.W. Alibocus M. Aliev g. Alimonti W. Alkakhi C. Allaire B.M.M. Allbrooke J.F. Allen C.A. Allendes Flores P.P. Allport A. Aloisio F. Alonso C. Alpigiani M. Alvarez Estevez A. Alvarez Fernandez M. Alves Cardoso M.g. Alviggi M. Aly Y. Amaral Coutinho A. Ambler C. Amelung M. Amerl C.g. Ames D. Amidei S.P. Amor Dos Santos K.R. Amos V. Ananiev C. Anastopoulos T. Andeen J.K. Anders S.Y. Andrean A. Andreazza S. Angelidakis A. Angerami A.V. Anisenkov A. Annovi C. Antel M.T. Anthony E. Antipov M. Antonelli F. Anulli M. Aoki T. Aoki J.A. Aparisi Pozo M.A. Aparo L. Aperio Bella C. Appelt A. Apyan N. Aranzabal S.J. Arbiol Val C. Arcangeletti A.T.H. Arce E. Arena J-F. Arguin S. Argyropoulos J.-H. Arling O. Arnaez H. Arnold g. Artoni H. Asada K. Asai S. Asai N.A. Asbah J. Assahsah K. Assamagan R. Astalos S. Atashi R.J. Atkin M. Atkinson H. Atmani P.A. Atmasiddha K. Augsten S. Auricchio A.D. Auriol V.A. Austrup g. Avolio K. Axiotis g. Azuelos D. Babal H. Bachacou K. Bachas A. Bachiu F. Backman A. Badea P. Bagnaia M. Bahmani A.J. Bailey V.R. Bailey J.T. Baines L. Baines O.K. Baker E. Bakos D. Bakshi gupta V. Balakrishnan R. Balasubramanian E.M. Baldin P. Balek E. Ballabene F. Balli L.M. Baltes W.K. Balunas J. Balz E. Banas M. Bandieramonte A. Bandyopadhyay S. Bansal L. Barak M. Barakat E.L. Barberio D. Barberis M. Barbero M.Z. Barel K.N. Barends T. Barillari M-S. Barisits T. Barklow P. Baron D.A. Baron Mo The ATLAS Collaboration

The identification of jets originating from quarks and gluons,often referred to as quark/gluon tagging,plays an important role in various analyses performed at the Large Hadron Collider,as Standard Model measurements and searches for new particles decaying to quarks often rely on suppressing a large gluon-induced background.This paper describes the measurement of the efficiencies of quark/gluon taggers developed within the ATLAS Collaboration,using √s=13 TeV proton–proton collision data with an integrated luminosity of 140 fb^(-1) collected by the ATLAS experiment.Two taggers with high performances in rejecting jets from gluon over jets from quarks are studied:one tagger is based on requirements on the number of inner-detector tracks associated with the jet,and the other combines several jet substructure observables using a boosted decision tree.A method is established to determine the quark/gluon fraction in data,by using quark/gluon-enriched subsamples defined by the jet pseudorapidity.Differences in tagging efficiency between data and simulation are provided for jets with transverse momentum between 500 geV and 2 TeV and for multiple tagger working points.

关键词： ATLAS JET QUARK gLUON TAggINg

Transcriptome driven characterization of curly-and smooth-leafed endives reveals molecular differences in the sesquiterpenoid pathway

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Horticulture Research 2019年第1期6卷 1715-1733页

作者： giulio Testone giovanni Mele Elisabetta di giacomo gian Carlo Tenore Maria gonnella Chiara Nicolodi giovanna Frugis Maria Adelaide Iannelli giuseppe Arnesi Alessandro Schiappa Tiziano Biancari Donato giannino Institute of Agricultural Biology and Biotechnology Unit of RomeNational Research Council of Italy(CNR)RomeItaly Department of Pharmacy University of Naples Federico IINapoliNAItaly Institute of Sciences of Food Production CNRBariItaly Enza Zaden Italia TarquiniaViterboItaly

Endives(Cichorium endivia L.)are popular vegetables,diversified into curly/frisée-and smooth/broad-leafed(escaroles)cultivar types(cultigroups),and consumed as fresh and bagged salads.They are rich in sesquiterpene lactones(STL)that exert proven function on bitter taste and human health.The assembly of a reference transcriptome of 77,022 unigenes and RNA-sequencing experiments were carried out to characterize the differences between endives and escaroles at the gene structural and expression levels.A set of 3177 SNPs distinguished smooth from curly cultivars,and an SNP-supported phylogenetic tree separated the cultigroups into two distinct clades,consistently with the botanical varieties of origin(crispum and latifolium,respectively).A pool of 699 genes maintained differential expression pattern(core-DEgs)in pairwise comparisons between curly vs smooth cultivars grown in the same environment.Accurate annotation allowed the identification of 26 genes in the sesquiterpenoid biosynthesis pathway,which included several germacrene A synthase,germacrene A oxidase and costunolide synthase members(gAS/gAO/COS module),required for the synthesis of costunolide,a key precursor of lactucopicrin-and lactucin-like sesquiterpene lactones.The core-DEgs contained a gAS gene(contig83192)that was positively correlated with STL levels and recurrently more expressed in curly than smooth endives,suggesting a cultigroup-specific behavior.The significant positive correlation of gAS/gAO/COS transcription and STL abundance(2.4-fold higher in frisée endives)suggested that sesquiterpenoid pathway control occurs at the transcriptional level.Based on correlation analyses,five transcription factors(MYB,MYB-related and WRKY)were inferred to act on contig83192/gAS and specific STL,suggesting the occurrence of two distinct routes in STL biosynthesis.

关键词： STL cultivar maintained