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国际医学放射学杂志 2024年第1期 128-128页

作者： H.Ahn T.M.Kim S.I.Hwang H.J.Lee g.choe S.K.Hong 曹琳

摘要目的评价肿瘤接触长度（TCL）对预测膀胱影像报告和数据系统（VIRADS）评分为2～3的病变中肌层浸润性膀胱癌（MIBC）的诊断效能。方法回顾性纳入一个机构2019

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Restimate:Recovery Estimation Tool for Resilience Planning

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Journal of Safety Science and Resilience 2024年第1期5卷 47-63页

作者： Scott Miles Megan Ly Nick Terry Youngjun choe Department of Human Centered Design&Engineering Campus Box 352315University of WashingtonSeattleWA 98195United States of America Department of Industrial&Systems Engineering Box 352650University of WashingtonSeattleWA 98195United States of America

The *** Institute of Standards and Technology(NIST)published the Community Resilience Planning guide in *** NIST guide advocates for a participatory process for developing a performance measurement framework for the jurisdiction’s resilience against a scenario *** framework centers around tables of expected and desired recovery times for selected community assets,such as electricity,water,and natural gas *** NIST guide does not provide a method for estimating the expected recovery ***,building high-fidelity computer models for such estimations requires substantial resources that even larger ju-risdictions cannot *** most promising approach to recovery time estimation is to systematically use data elicited from people to tap into the wisdom of the(knowledgeable)*** paper describes a novel research-through-design project to enable the computer-supported elicitation of recovery time series *** work is the first in the literature to examine people’s ability to estimate recovery curves and how design in-fluences such *** main contribution to resilience planning is three-fold:development of a new elicitation tool called Restimate,understanding its potential user base,and providing insights into how it can facilitate resilience *** is the first tool to enable evidence-based expert elicitation in any community with limited resources for resilience *** resilience planning,those who facilitate high-stakes planning activities under large uncertainties(e.g.,mission-critical system design and planning)will benefit from a similar research-through-design process.

关键词： expert elicitation disaster natural hazard infrastructure community resilience restoration user-centered design computer-supported cooperative work

Suicide risk in juvenile open angle glaucoma patients

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International Journal of Ophthalmology(English edition) 2024年第10期17卷 1880-1886页

作者： Hye-Jeong Seong Sukyoung Jung Sooyeon choe Department of Ophthalmology Chungnam National University HospitalDaejeon 35015Republic of Korea Department of Ophthalmology Chungnam National University College of MedicineDaejeon 35015Republic of Korea Department of Health Care Policy Research Korea Institute for Health and Social AffairsSejong 30147Republic of Korea

AIM:To investigate the association between juvenile open angle glaucoma(JOAg)and mental health among ***:This study used nationally representative data from the 8th Korea National Health and Nutrition Examination Survey(KNHANES)*** diagnosis followed the International Society of geographical and Epidemiological Ophthalmology criteria based on glaucomatous structural defects,visual field defects,corrected vision,and intraocular *** outcomes,suicidal behaviors,psychiatric counseling,and depression were evaluated through mental health *** ratios(ORs)with 95%confidence intervals(CIs)were estimated using logistic regression models,adjusting for ***:Among 7090 participants,3446 met the inclusion criteria for analysis,and 88(2.6%)were diagnosed with open angle glaucoma(OAg).After adjusting for age,sex,and best-corrected visual acuity(VA),participants with OAg were revealed to have significantly higher odds of suicidal behaviors(i.e.,ideation,planning,or attempts)compared with those without OAg(OR:2.70;95%CI:1.12-6.54;P=0.028).This association remained significant after further adjustments for socioeconomic status,lifestyle factors,and presence of chronic conditions(P=0.031 and 0.035,respectively).However,there was no significant difference for the other two outcomes,psychiatric counseling and *** age-stratified analysis revealed a stronger association between OAg and suicidal behaviors in younger JOAg participants(g participants(≥40y;OR:3.80 vs 2.22;95%CI:0.79-18.22 vs 0.56-8.80,respectively).CONCLUSION:OAg patients show a higher risk of suicidal behaviors than those without glaucoma particularly in JOAg patients.

关键词： glaucoma juvenile open angle glaucoma suicide suicidal behavior

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多参数MRI预测前列腺前部癌包膜外侵犯

国际医学放射学杂志 2020年第2期 243-243页

作者： H.Ahn S.I.Hwang H.J.Lee H.S.Suh g.choe S.S.Byun 冀晓莉 Department of Radiology Seoul National University Bundang Hospital

目的验证既往已确认的包膜外侵犯(EPE)的征象如何用于前列腺前部癌(APC)评估,并探讨是否有其他新征象。方法回顾性分析2011—2016年组织病理学证实614

关键词：接触长度 EPE 肿瘤长径 MRI 前列腺

Production of chitosan-based composite film reinforced with lignin-rich lignocellulose nanofibers from rice husk

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Journal of Bioresources and Bioproducts 2024年第2期9卷 174-184页

作者： Hye Jee Kang Yeon Ju Lee Jin Kyoung Lee Irnia Nurika Sri Suhartini Deokyeong.choe Dong Hyun Kim Hoon Choi Natasha P.Murphy Ho Yong Kim Young Hoon Jung School of Food Science and Biotechnology Kyungpook National UniversityDaegu 41566Republic of Korea CPR S&T Co. Ltd.Gunpo 15880Republic of Korea Department of Agroindustrial Technology Faculty of Agricultural TechnologyUniversitas BrawijayaMalang 65145Indonesia Renewable Resources and Enabling Sciences Center National Renewable Energy LaboratoryGoldenCO 80401United States Center for Bio-based Chemistry Korea Research Institute of Chemical TechnologyUlsan 44429Republic of Korea

Lignocellulosic nanofibers(LCNFs),implying lignin-containing cellulose fibers,maintain the prop-erties of both lignin and cellulose,which are hydrophobic and hydrophilic,*** pres-ence of hydrophobic lignin in LCNFs is expected to be an economical and attractive option that can improve the thermal and mechanical properties of ***,this study was conducted to produce lignin-rich LCNFs from sugar-rich waste obtained from rice husks after acidic *** LCNFs were produced from the lignin-rich solid fractions obtained after pretreatment and enzymatic hydrolysis,which were then incorporated as an additive into a chitosan-based *** variations in lignin content in the range of approximately 50.6%-66.8%in differently obtained LCNFs gave significantly different optical strengths and mechanical *** controllable processes may allow for customized film ***,the glucose-rich liquid fractions obtained after pretreatment and enzymatic hydrolysis were used as a substrate for ethanol fermentation to achieve total utilization of rice husk biomass *** conclusion,the lignin-rich biomass fraction holds promise as a suitable material for chitosan-LCNF film and has the potential to increase the economic feasibility of the biomaterial industry.

关键词： Rice husk Lignocellulose nanofiber Lignin-based material Chitosan film Upcycling

Antimicrobial stewardship and targeted therapies in the changing landscape of maternal sepsis

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Journal of Intensive Medicine 2024年第1期4卷 46-61页

作者： Nishel M Shah Esmita Charani Damien Ming Fook-choe Cheah Mark R Johnson Department of Metabolism Digestion and ReproductionImperial College LondonChelsea and Westminster HospitalLondonUK Health Protection Research Unit in Healthcare Associated Infection and Antimicrobial Resistance Imperial College LondonLondonUK Division of Infectious Diseases and HIV Medicine Department of MedicineGroote Schuur HospitalUniversity of Cape TownCape TownSouth Africa Department of Infectious Diseases Imperial College LondonChelsea and Westminster HospitalLondonUK Department of Paediatrics Faculty of MedicineUniversiti Kebangsaan Malaysia Medical CentreKuala LumpurMalaysia

Pregnant and postnatal women are a high-risk population particularly prone to rapid progression to sepsis with significant morbidity and mortality ***,severe maternal infections can have a serious detrimental impact on neonates with almost 1 million neonatal deaths annually attributed to maternal infection or *** this review we discuss the susceptibility of pregnant women and their specific physiological and immunological adaptations that contribute to their vulnerability to sepsis,the implications for the neonate,as well as the issues with antimicrobial stewardship and the challenges this poses when attempting to reach a balance between clinical care and urgent ***,we review advancements in the development of pregnancy-specific diagnostic and therapeutic approaches and how these can be used to optimize the care of pregnant women and neonates.

关键词： Sepsis Pregnancy Immunology Cardiovascular Personalised medicine Antibiotic stewardship

What physicians should know about the management of chronic hepatitis B in children: East side story

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World Journal of gastroenterology 2014年第13期20卷 3582-3589页

作者： Hun-Jee choe Byung-Ho choe Seoul National University College of Medicine Seoul 110-799South Korea Department of Pediatrics Kyungpook National University School of MedicineDaegu 700-721South Korea

Understanding the natural course of chronic hepatitis B virus(HBV)infection is very important for the management and treatment of chronic hepatitis B in *** on treatment guidelines,the management of HBV carriers and treatment of active hepatitis have been advancing and resulted in increased survival,as well as decreased risks of complications such as liver cirrhosis and hepatocellular *** of a continuing medical education(CME)program for primary physicians becomes an important responsibility of pediatric *** could prevent misdiagnosis and unnecessary treatment that could lead to liver complications or antiviral *** addition,education of patients and their parents is necessary to achieve better therapeutic outcomes.

关键词： Hepatitis B virus Natural course Diagnosis Treatment Lamivudine Resistance

Fouling evaluation on membrane distillation used for reducing solvent in polyphenol rich propolis extract

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Chinese Journal of Chemical Engineering 2018年第3期26卷 477-483页

作者： Norhaziyana Hamzah choe Peng Leo School of Chemical Engineering Engineering Campus Universiti Sains Malaysia

Membrane distillation(MD) has not been widely studied in the concentrate of phenolic rich solution in comparison to osmotic distillation. In this work, the potential of MD to reduce solvent in the polyphenol rich propolis extract was further investigated. Polyvinylidene fluoride(PVDF) membranes were engineered with the smaller pore size for the less hydrophobic surface in order to avoid wetting, allowing only the solvent vapor to be transferred from the warm feed into the cold permeate. All the membranes exhibited more than 95% rejection of phenolic and flavonoid compounds. Although the hydrophilic membranes exhibited less fouling, they displayed a lower flux than the hydrophobic membrane due to the hindrance in the wetted pores. The hydrophobic membrane was seriously fouled by the phenolic acid as shown in the Fourier transform infrared spectroscopy spectrum. Pore plugging occurred on these hydrophobic membranes as confirmed in the scanning electron microscope images.

关键词： Membrane distillation Propolis Fouling

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Spontaneous high-frequency action potential

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Science China(Life Sciences) 2011年第4期54卷 311-335页

作者： Wonchae choe Department of Biochemistry and Molecular Biology Medical Research Center and Biomedical Science InstituteSchool of MedicineKyung Hee University

Action potential,which is the foundation of physiology and electrophysiology,is most vital in physiological *** work starts by detecting cardiac electrophysiology(tachyarrhythmias),combined with all spontaneous discharge phenomena in vivo such as wound currents and spontaneous neuropathic pain,elaborates from generation,induction,initiation,to all of the features of spontaneous high-frequency action potential--SSL action potential mechanism,i.e.,connecting-end hyperpolarization initiates spontaneous depolarization and action potential in somatic *** work resolves the conundrums of in vivo spontaneous discharge in tachyarrhythmias,wounds,denervation supersensitivity,neurogenic pain(hyperalgesia and allodynia),epileptic discharge and diabetic pain in pathophysiological and clinical researches that have puzzled people for a hundred years.

关键词： action potential spontaneous high-frequency action potential tachyarrhythmias atrial fibrillation wound denervation supersensitivity neurogenic pain hyperalgesia and allodynia epileptic discharge diabetic pain regeneration and development

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Data-driven sparse polynomial chaos expansion for models with dependent inputs

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Journal of Safety Science and Resilience 2023年第4期4卷 358-365页

作者： Zhanlin Liu Youngjun choe Industrial&Systems Engineering University of WashingtonSeattleWAUSA

Polynomial chaos expansions(PCEs)have been used in many real-world engineering applications to quantify how the uncertainty of an output is propagated from inputs by decomposing the output in terms of polynomials of the *** for models with independent inputs have been extensively explored in the ***,different approaches have been proposed for models with dependent inputs to expand the use of PCEs to more real-world *** approaches include building PCEs based on the gram–Schmidt algorithm or transforming the dependent inputs into independent ***,the two approaches have their limitations regarding computational efficiency and additional assumptions about the input distributions,*** this paper,we propose a data-driven approach to build sparse PCEs for models with dependent inputs without any distributional *** proposed algorithm recursively constructs orthonormal polynomials using a set of monomials based on their correlations with the *** proposed algorithm on building sparse PCEs not only reduces the number of minimally required observations but also improves the numerical stability and computational *** numerical examples are implemented to validate the proposed *** source code is made publicly available for reproducibility.

关键词： Uncertainty quantification Polynomial chaos expansion Sparse polynomial chaos expansion gram-Schmidt orthogonalization