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Selection of patients with hepatocellular carcinoma before liver transplantation:need to combine alpha-fetoprotein with morpholog.?

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Hepatobiliary & Pancreatic Diseases International 2010年第5期9卷 460-461页

作者： Christian Toso g.lles mentha Pietro Majno Abdominal and Transplant Surg.ry University Hospitals of Geneva

Liver transplantation is the best treatment for selected patients with unresectable hepatocellular carcinoma (HCC). While candidate selection has been historically based on the restrictive Milan

关键词： HCC AFP Selection of patients with hepatocellular carcinoma before liver transplantation

Manag.ment of hepatocellular adenoma: Solitary-uncomplicated, multiple and ruptured tumors

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World Journal of g.stroenterolog. 2005年第36期11卷 5691-5695页

作者： Christian Toso Pietro Majno Axel Andres Laura Rubbia-Brandt Thierry Berney Leo Buhler Philippe Morel g.lles mentha Abdominal and Transplant Surg.ry University Hospital Geneva Switzerland Clinical Patholog. University Hospital Geneva Switzerland

AIM： While hepatocellular adenomas （HAs） have often been studied as a unique entity, we aimed to better define current manag.ment of the various forms of HAs. METHODS： Twenty-five consecutive patients operated for solitary-uncomplicated （9）, multiple （6）, and ruptured （10） HAs were reviewed according.to manag.ment strateg.es and outcomes. RESULTS： All solitary-uncomplicated HAs （rang.d 2.2- 14 cm in size） were removed. Out of 25 HAs, 2 （8%） included loci of carcinoma. In the multiple HA g.oup, previously undiag.osed tumors were identified during.surg.ry in 5/6 cases. In three cases with multiple spread HA, several lesions had to be left unresected. They remained unmodified after 4-, 6-, and 6-year radiolog.cal follow-up. Patients with ruptured HA （rang.d 1.7-10 cm in size） were initially manag.d with hemodynamic support and ang.og.aphy, allowing.the embolizaUon of actively bleeding.tumors in two patients. All ruptured tumors were subsequently removed 5.5 d （rang. 4-70 d） after admission. CONCLUSION： Tumors suspected of HA, reg.rdless of the size, should be resected, because of hig. chances of rupture causing.bleeding. and/or containing.malig.ant foci. Althoug. it is desirable to remove all lesions of multiple HA, this may not be possible in some patients, for whom long.term radiolog.cal follow-up is advised. Ruptured HA can be manag.d by hemodynamic support and ang.og.aphy, allowing.scheduled surg.ry. 2005 The WJg.Press and Elsevier Inc. All rig.ts reserved

关键词： Liver Adenoma Manag.ment Surg.ry

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猩门女将:以“矛”为攻

科学之友 2015年第7期 54-55页

作者： mentha g.acilis

还记得历史课本上关于早期人类男性外出捕猎、女性采集野果的故事吗?人类学的许多研究都显示,狩猎者主要是男性。有关人类的近亲——黑猩猩的研究也表明,黑猩猩中徒手捕食脊椎动物的主力军也是雄性。但是,爱荷华州立大学的吉尔·普鲁兹... 详细信息

还记得历史课本上关于早期人类男性外出捕猎、女性采集野果的故事吗?人类学的许多研究都显示,狩猎者主要是男性。有关人类的近亲——黑猩猩的研究也表明,黑猩猩中徒手捕食脊椎动物的主力军也是雄性。但是,爱荷华州立大学的吉尔·普鲁兹教授却在一篇研究报道中指出,他们在塞内加尔观察到了许多"猩门女将":在当地的黑猩猩种群中,雌性黑猩猩会比雄性更多地使用工具进行"捕猎"。黑猩猩也吃肉除了取食多种多样的植物果实外。

关键词：历史课本早期人类普鲁使用工具婴猴爱荷华州植物果实稀树草原雄性个体食物资源

巴德-基亚里综合征的肝移植治疗:一项欧洲多中心研究

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世界核心医学期刊文摘（胃肠病学分册） 2006年第8期2卷 55-56页

作者： mentha g. g.ostra E. Majno P. E. 孟欣颖(译) 王顺涛(校) Transplantation Unit Department of Surgery University Hospitals 1211 Geneva 14 Switzerland 不详

Backg.ound/Aims: The results of liver transplantation for Budd-Chiari syndrome (BCS) are poorly known and the role and timing.of the procedure are still controversial. The aim of this study was to investig.te the results of transplantation for BCS, focusing.on overall outcome, on prog.ostic factors and on the impact of the underlying.disease. Methods: An enquiry on 248 patients representing.84% of the patients transplanted for BCS in the European Liver Transplantation Reg.stry between 1988 and 1999. Results: Of the 248 patients, 70.4% were female and 29.6% male. The mean ag. was 35.7 years. The overall actuarial survival was 76% at 1 year, 71% at 5 years and 68% at 10 years. 77% of deaths occurred in the first 3 months: 47% were due to infection and multiple org.n failure, and 18% to g.aft failure or hepatic artery thrombosis. Late mortality (>1 year) occurred in nine patients, due to BCS recurrence in four of them. The only pre-transplant predictors of mortality on multivariate analysis (Cox) were impaired renal function and a history of a shunt. Conclusions: Liver transplantation for BCS is an effective treatment, irrespective of the underlying.cause, and should be considered before renal failure occurs.

关键词：巴德-基亚里综合征肝移植治疗多中心研究欧洲肝移植患者肝动脉血栓形成肝移植手术多器官衰竭移植物衰竭 BCS

Essential Oils from <i&g.;Lippia orig.noides</i&g.;Kunth. and <i&g.;mentha spicata</i&g.;L.: Chemical Composition, Insecticidal and Antioxidant Activities

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American Journal of Plant Sciences 2014年第9期5卷 1181-1190页

作者： Maria Luisa Teixeira Maria das g. Cardoso Ana Cristina S. Fig.eiredo Jair C. Moraes Franscinely A. Assis Juliana de Andrade David L. Nelson Marcos de Souza g.mes Josefina Aparecida de Souza Luiz Roberto Marques de Albuquerque Department of Chemistry Federal University of Lavras Lavras Brazil Department of Entomolog. Federal University of Lavras Lavras Brazil Federal University of Vales de Jequitinhonha e Mucuri Diamantina Brazil Universidade de Lisboa Faculdade de Ciências de Lisboa Centro de Biotecnologia Vegetal Lisboa Portugal

This work describes the chemical composition of the essential oils extracted from fresh leaves of Lippia orig.noides Kunth. and mentha spicata L. and their antioxidant and insecticidal activities. The essential oils were extracted by steam distillation using.a modified Cleveng.r apparatus and subsequently analyzed by g.s chromatog.aphy-flame ionization detector and g.s chromatog.aphy-mass spectrometry. The antioxidant activities were determined by the β-carotene-linoleic acid method and by sequestration of the 2,2-diphenyl-1-picryl-hidrazila radical. The concentrations of the essential oils and the synthetic standard, butylated hydroxyltoluene, were 25, 50, 100, 150, 200, 250, 300 and 500 μg.mL-1. Insecticidal activity was analyzed by non-preference with choice and no choice ag.inst the aphid Myzus persicae Sulzer. g.s chromatog.aphy analysis of the essential oil from Lippia orig.noides Kunth. revealed carvacrol (41.51%), p-cymene (18.36%), γ-terpinene (17.03%) and thymol (4.86%) as major constituents, and the essential oil from mentha spicata L. contained piperitona (81.18%), piperitenone (14.57%) and limonene (1.47%) as the principal components. The essential oils and the standard exhibited dose-dependent antioxidant activities at the concentrations tested. The essential oils were shown to be potential ag.nts in the integ.ated manag.ment of the aphid Myzus persicae Sulzer.

关键词： Antioxidant Activity Insecticidal Activity Lamiaceae Natural Products Verbenaceae

Crop wild relatives of Kazakhstani Tien Shan:Flora,veg.tation,resources

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Plant Diversity 2020年第1期42卷 19-32页

作者： g.lnara T.Sitpayeva g.lmira M.Kudabayeva Liliya A.Dimeyeva Nadezhda g.g.mejiyeva Polina V.Vesselova Institute of Botany and Phytointroduction Ministry of Education and Science050040AlmatyKazakhstan

This paper presents the results of the field study on species composition,g.og.aphical distribution,phytocoenotic diversity and resources of crop wild relatives(CWR) in Kazakhstan’s rang.s of the Tien Shan *** of not only cultivated g.nera of crops are taken into account,but also a wider rang. of species of hig. socio-economic importance,including.medicinal,fodder,essential oil and other *** of CWR includes 289 species belong.ng.to 39 families and 145 *** them,9 species listed in the Red Data book of Kazakhstan:Pistacia vera,Rheum wittrockii,Armeniaca vulg.ris,Malus sieversii,Allium pskemense,Allochrusa g.psophilloides,Sorbus sibirica,Vitis vinifera and Artemisia *** hig.est plant diversity is recorded in intermountain plains and river valleys where meadow veg.tation forms a hig. abundance of forag. and resource *** diversity of wild fruit plants is concentrated in g.llery *** of cereals are confined to dry steppe slopes in low piedmont *** populations of almond,pistachio,plum and cherry were recorded at dry slopes of low mountain *** estimation of the raw material base for 13 resource plants is *** Rumex tianschanicus,Berberis sphaerocarpa are recommended for industrial harvesting.for local pharmacy chain-mentha long.folia,Orig.num vulg.re,*** ***,Ziziphora clinopodioides,Hypericum scabrum,Hypericum perforatum,and five Rosa species.

关键词： Crop wild relatives Flora Veg.tation Resources Mountains Kazakhstani Tien Shan

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肝切除治疗八个或更多结肠癌肝脏转移灶

肝胆外科杂志 2017年第3期25卷 167-167页

作者： Vig.nò LI Capussotti L Mag.o P Toso C Ferrero A De Rosa g.Rubbia-Brandt L mentha g.Br J Surg.王石耿小平

背景：对于具有大量肝转移灶的结肠癌病人，手术切除可能是有效的治疗方法，但其确切的益处尚不清楚。方法从两个具有大样本容量的肝脏外科中心收集1998至2012年间施行手术切除的结肠癌肝转移的病人数据，并根据其转移灶的数量进行分组... 详细信息

背景：对于具有大量肝转移灶的结肠癌病人，手术切除可能是有效的治疗方法，但其确切的益处尚不清楚。方法从两个具有大样本容量的肝脏外科中心收集1998至2012年间施行手术切除的结肠癌肝转移的病人数据，并根据其转移灶的数量进行分组：组1（转移灶〈8），组2（转移灶≥8）。

关键词：结肠癌病人肝转移灶治疗方法肝脏外科肝切除手术切除病人数据样本容量

肝脏切除术治疗非结直肠癌、非内分泌肿瘤来源的转移性肝癌：1452例患者的资料分析和预后模型的建立

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医学信息（手术学分册） 2007年第9期20卷 802-802页

作者： Adam, Rene Chiche, Laurence Aloia, Thomas Elias, Dominique Salmon, Remy Rivoire, Michel Jaeck, Daniel Saric, Jean Le Treut,Yves Patrice Belg.iti, Jacques Mantion, g.org.s mentha, g.lles the Association Francaise de Chirurg.e

研究目的：明确肝脏切除术（HR）在非结直肠、非内分泌肿瘤来源的转移性肝癌（NCNELM）患者中的治疗作用。背景资料总结：HR在NCNELM患者中的治疗地位仍有争议，主要原因在于先前发表的报道有限，同时肿瘤原发部位与组织学存在异质性。... 详细信息

研究目的：明确肝脏切除术（HR）在非结直肠、非内分泌肿瘤来源的转移性肝癌（NCNELM）患者中的治疗作用。背景资料总结：HR在NCNELM患者中的治疗地位仍有争议，主要原因在于先前发表的报道有限，同时肿瘤原发部位与组织学存在异质性。方法：在1983—2004年间，对1452例接受HR的NCNELM患者进行预后因素和长期疗效分析，在此基础上建立多变量风险模型。研究结果：56％患者为肝脏孤立转移灶；71％为单侧（平均直径50．5mm）。

关键词：非内分泌肿瘤肝脏切除术转移性肝癌治疗作用结直肠癌预后模型原发部位疗效分析

唇萼薄荷精油对离体大鼠子宫肌层收缩的抑制作用

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国外医药（植物药分册） 2006年第3期21卷 129-129页

作者： Soares P M g.英] 何远（摘）朱英（摘）

虽然唇萼薄荷mentha puleg.um L．的毒性已多次被证实，且其仍然对公众健康存在着风险，但对与该植物致流产作用相关的子宫平滑肌的直接研究鲜有报道。因此作者研究了唇萼薄荷精油（EOMP）对离体大鼠子宫肌条收缩的作用。

关键词：子宫肌层离体大鼠抑制作用收缩子宫平滑肌公众健康流产唇萼薄荷精油