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Simulation of Mould Level Velocities During Continuous Casting of Round Bloom Strands With Mould-Electromagnetic Stirring

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Journal of Iron and Steel Research International 2012年第S2期19卷 884-887页

作者： BARNAMartin JAVUREK Mirko reiter Jurgen WATZINgER Josef KAUFMANN Bernhard HACKL gemot Institute for Fluid Mechanics and Heat Transfer Johannes-Kepler-University-Linz Voestalpine Stahl Donawitz gmbH and Co Kg Siemens VAI Metals Technologies gmbH and Co Voestalpine Stahl gmbH RHI Ag Technology Center Leoben

In modern continuous casting of round steel blooms rotating electromagnetic fields are commonly employed to improve the product ***-electromagnetic stirrers(M-EMS)are used to excite a rotary motion along the solidification front in the liquid *** velocities lead to a better strand surface quality as well as enhancing the transition from columnar to equiaxed *** the usage of electromagnetic stirrers is widespread,not all effects are fully known or *** to harsh conditions at the plant,measurements are scarce and *** model experiments-an established alternative for investigating continuous casting of steel-cannot be used due to the low electrical conductivity of *** with liquid metals like mercury,galinstan or Wood’s metal are either expensive or difficult to *** numeric simulations are essential to gain a better understanding of the processes involved in continuous casting with electromagnetic *** numeric simulations should always be validated with experiments and/or *** the velocity field inside the liquid core of the bloom cannot be measured at the caster,the velocity at the mould level can be measured by dipping a nail into *** skull forming at the tip of the nail is directly linked to the occurring surface *** measurements can then be compared with numeric simulations of the nail dipping *** numeric model is restricted to the upper part of the *** lower part of the strand is also taken into account through adjusted boundary conditions(velocity field *** from a simulation of the whole strand).In this work the influence of the stirring field strength on the simulation results will be *** the future these nail dipping simulations will be validated with plant *** can then to a certain extentvalidate the simulation of the strand with M-EMS too,as it serves as the basis for the nail dipping model.

关键词： continuous casting of steel mould-electromagnetic stirring velocity measurements finite volume method

Diode-pumped,electro-optically Q-switched,cryogenic Tm:YAg laser operating at 1.88 μm

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High Power Laser Science and Engineering 2021年第1期9卷 103-108页

作者： Jörg Körner Venkatesan Jambunathan Fangxin Yue Jürgen reiter Ondrej Slezák Petr Navrátil Samuel Paul David Antonio Lucianetti Joachim Hein TomášMocek Malte CKaluza HiLASE Centre Institute of Physics of the Czech Academy of SciencesDolníBrežanyCzech Republic Institute of Optics and Quantum Electronics Friedrich Schiller University JenaJenaGermany Helmholz Institute Jena JenaGermany

We present a diode-pumped, electro-optically Q-switched Tm:YAg laser with a cryogenically cooled laser crystal at120 K. Output pulses of up to 2.55 mJ and 650 ns duration were demonstrated in an actively Q-switched configuration with a repetition rate of 1 Hz. By using cavity dumping the pulse duration was shortened to 18 ns with only a slightly lower output energy of 2.22 mJ. Furthermore, using a simplified rate equation model, we discuss design constraints on the pump fluence in a pulse pump approach for Tm:YAg to maximize the energy storage capability at a given pump power.

关键词： cryogenic condition laser Q-switch short-wave infrared Tm:YAg

Promotion of liquid-to-solid phase transition of cgAS by Baicalein suppresses lung tumorigenesis

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Signal Transduction and Targeted Therapy 2023年第4期8卷 1392-1395页

作者： Tiansheng Zheng Haipeng Liu Yifan Hong Yajuan Cao Qing Xia Chengge Qin Ming Li Russel J.reiter Yidong Bai Lihong Fan Department of Respiratory Medicine Shanghai Tenth People’s HospitalTongji University School of MedicineShanghai 200072China Department of Integrated Traditional Chinese&Western Medicine Shanghai Tenth People’s HospitalTongji University School of MedicineShanghai 200072China Clinical Translational Research Center Shanghai Pulmonary HospitalTongji University School of MedicineShanghai 200433China Institute of Energy Metabolism and Health Shanghai Tenth People’s HospitalTongji University School of MedicineShanghai 200072China Institute of Molecular Physiology Institue of Cancer ResearchShenzhen Bay LaboratoryShenzhen 518132China Medical School of Nantong University NantongJiangsu 22601China Department of Cell Systems and Anatomy University of Texas Health San AntonioSan AntonioTexas 78229USA

Dear Editor,Kras and p53 mutation are among the most common gene mutations in lung cancer,which has both the highest incidence and mortality rate among cancers.1 Kras/p53 mutation also causes mitochondrial dysfunction,which has been implicated to promote the inflammation-to-cancer transition.2 We established a lung adenocarcinoma model by using conditional alleles of KrasLSLg12D/p53flox/flox in mice3 to evaluate the effect of Baicalein(5,6,7-trihydroxyflavone),a principal component of Scutellaria baicalensis in traditional Chinese medicine,4 on the initiation and progression of lung ***-mediated expression of Krasg12D and deletion of p53 caused obvious tumor lesions in the lung,which were strongly inhibited by the administration of Baicalein(Fig.1a,b and Supplementary Fig.1a,b),indicating that Baicalein is highly potent in inhibiting the progression of primary lung cancer.

关键词： lung Baicalein inhibited

LARgE-SCALE CIRCULATION CONDITIONS AFFECTINg THE HURRICANE FORMATION OVER THE NORTH ATLANTIC OCEAN

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Acta Oceanologica Sinica 1985年第1期 21-34页

作者：丁一汇,ELMARR.reiter Institute of Atmospheric Physics Academia Sinica Department of Atmospheric Sciences Colorado State University U.S.A.

A contrasting study of the large-scale circulation features responsible for months or seasons with many hurricanes and those with few hurricanes has revealed that the frequency of hurricane formation over the North Atlantic Ocean is enhanced by the following conditions:There exists a well-developed subtropical high-pressure belt displaced to the north; a deep Icelandic low; a stronger-than-normal polar vortex with a deep polar trough dipping far southward along the eastern part of the United States; a dominant high-pressure ridge over western Canada and the United States; and a jet stream displaced northward over these regions. At 200 hPa, an anomalous anticyclonic circulation prevails over the subtropical North Atlantic. A stronger-than-normal upper easterly flow prevails. Positive sea surface temperature anomalies prevailing on a seasonal or long-term basis tend to be favorable for the formation of hurricanes.

关键词： over LARgE-SCALE CIRCULATION CONDITIONS AFFECTINg THE HURRICANE FORMATION OVER THE NORTH ATLANTIC OCEAN

Effect of melatonin on the severity of L-arginine-induced experimental acute pancreatitis in rats

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World Journal of gastroenterology 2006年第2期12卷 251-258页

作者： Annamaria Szabolcs Russel J reiter Tamas Letoha Peter Hegyi gabor Papai Ilona Varga Katalin Jarmay Jozsef Kaszaki Reka Sari Zoltan Rakonczay Jr Janos Lonovics Tamas Takacs st Department of Medicine University of SzegedHungary Department of Cellular and Structural Biology University of TexasHealth Science CentreSan AntonioTexasUnited States Institute of Chemistry University of SzegedHungary Biological Research Centre Hungarian Academy of SciencesSzegedHungary Biological Isotope Laboratory University of SzegedHungary Institute of Experimental Surgery University of SzegedHungary

AIM： To determine the effect of melatonin pre- and post-treatment on the severity of L-arginine （L-Arg） -induced experimental pancreatitis in rats. METHODS： Male Wistar rats （25） were divided into five groups. Those in group A received two injections of 3.2 g/kg body weight L-Arg i.p. at an interval of 1 h. In group MA, the rats were treated with 50 mg/kg body weight melatonin i.p. 30 min prior to L-Arg administration. In group AM, the rats received the same dose of melatonin 1 h after L-Arg was given. In group M, a single dose of melatonin was administered as described previously. In group C the control animals received physiological saline injections i.p. All rats were exsanguinated 24 h after the second L-Arg injection. RESULTS： L-Arg administration caused severe necrotizing pancreatitis confirmed by the significant elevations in the serum amylase level, the pancreatic weight/body weight ratio （pw/bw）, the pancreatic IL-6 content and the myeloperoxidase activity, relative to the control values. Elevation of the serum amylase level was significantly reduced in rats given melatonin following L-Arg compared to rats injected with L-Arg only. The activities of the pancreatic antioxidant enzymes （Cu/Zn-superoxide dismutase （CulZn-SOD） and catalase （CAT）） were significantly increased 24 h after pancreatitis induction. Melatonin given in advance of L-Arg significantly reduced the pancreatic CAT activity relative to that in the rats treated with L-Arg alone. In the liver, L-Arg significantly increased the lipid peroxidation level, and the glutathione peroxidase and Cu/Zn-SOD activities, whereas the Mn-SOD activity was reduced as compared to the control rats. Melatonin pre-treatment prevented these changes. CONCLUSION： Melatonin is an antioxidant that is able to counteract some of the L-Arg-induced changes during acute pancreatitis, and may therefore be helpful in the supportive therapy of patients with acute necrotizing pancreatitis.

关键词： Acute pancreatitis Melatonin Scavengers

LARgE-SCALE CIRCULATION CONDITIONS AFFECTINgTHE TYPHOON FORMATION OVER THENORTHWEST PACIFIC

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Acta Oceanologica Sinica 1984年第3期 327-338页

作者：丁一汇,ELMAR R. reiter Institute of Atmospheric Physics Academia Sinica Beijing Department of Atmospheric Science Colorado State University USA

A contrasting study of the large-scale circulation features responsible for months with many typhoons and months with tew typhoons has revealed that the frequency of typhoon formation over the Northwest Pacific is related to the following conditions:Over the Northwest Pacific, a well-defined ITCZ (Intertropical Convergence Zone) extending eastward to 160°E was displaced to 20°N. At 200 mb, an extensive anomalous anticyclonic circulation prevails over the western and central Pacific. The condition characteristic of a break in the monsoon prevailed in India. The monsoon trough at 500 mb and at the surface over the Indian Peninsula was relatively weak and was accompanied by higher-than-normal rainfall in the northern part of India and lower-than-normal rainfall over the peninsula. In addition, the polar vortex tends to be weak and move to the side of the Northern Hemisphere, opposite to the North Pacific. Finally, abnormally warm water was observed over the Central and Eastern Pacific and abnormally cold

关键词： over LARgE-SCALE CIRCULATION CONDITIONS AFFECTINgTHE TYPHOON FORMATION OVER THENORTHWEST PACIFIC

The mechanisms of sorafenib resistance in hepatocellular carcinoma:theoretical basis and therapeutic aspects

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Signal Transduction and Targeted Therapy 2020年第1期5卷 1713-1727页

作者： Weiwei Tang Ziyi Chen Wenling Zhang Ye Cheng Betty Zhang Fan Wu Qian Wang Shouju Wang Dawei Rong F.P.reiter E.N.De Toni Xuehao Wang Department of general Surgery Nanjing First HospitalNanjing Medical UniversityNanjingChina Hepatobiliary/Liver Transplantation Center The First Affiliated Hospital of Nanjing Medical UniversityKey Laboratory of Living Donor TransplantationChinese Academy of Medical SciencesNanjingChina Department of gastroenterology The First Affiliated Hospital of Nanjing Medical UniversityNanjingChina Michael g.Degroote School of Medicine McMaster UniversityHamiltonONCanada Department of Radiology The First Affiliated Hospital of Nanjing Medical UniversityNanjingChina Department of Medicine II University HospitalLMUMunichGermany Liver Center Munich University HospitalLMUMunichGermany

Sorafenib is a multikinase inhibitor capable of facilitating apoptosis,mitigating angiogenesis and suppressing tumor cell *** late-stage hepatocellular carcinoma(HCC),sorafenib is currently an effective first-line ***,the development of drug resistance to sorafenib is becoming increasingly *** study aims to identify factors contributing to resistance and ways to mitigate *** studies have shown that epigenetics,transport processes,regulated cell death,and the tumor microenvironment are involved in the development of sorafenib resistance in HCC and subsequent HCC *** study summarizes discoveries achieved recently in terms of the principles of sorafenib resistance and outlines approaches suitable for improving therapeutic outcomes for HCC patients.

关键词： sorafenib therapeutic hepatocellular

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血清中43种滥用药物的固相萃取法研究

云南大学学报（自然科学版） 2003年第5期25卷 434-437,441页

作者：杨丽君 reiter A 云南公安高等专科学校禁毒系云南昆明650223 吕贝克医科大学法医研究所德国吕贝克d23562

使用CLEANSCREEN○R　固相萃取柱分别对血清中43种滥用药物进行提取方法的研究,其提取物分别采用gC-MS和UV方法测定.结果表明:在43种滥用药物中,回收率超过90%的药物有26种,居80%～90%的药物有8种,居60%～80%的药物有另外8种,小于60%的... 详细信息

使用CLEANSCREEN○R　固相萃取柱分别对血清中43种滥用药物进行提取方法的研究,其提取物分别采用gC-MS和UV方法测定.结果表明:在43种滥用药物中,回收率超过90%的药物有26种,居80%～90%的药物有8种,居60%～80%的药物有另外8种,小于60%的药物仅有1种.因此CLEANSCREEN○R　固相萃取柱可用于血清中该43种滥用药物的提取或筛选分析,且是一种快速、简便及具有较高回收率的提取方法.

关键词：血清检测滥用药物含量测定固相萃取法 CLEAN-SCREEN固相萃取柱 gC—MS方法 UV方法

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Ti64合金的电子束冷床熔炼研究(英文)

稀有金属材料与工程 2008年第11期37卷 1973-1977页

作者：张英明周廉孙军韩明臣 georg reiter Jochen Flinspach 杨建朝赵永庆西安交通大学陕西西安710049 西北有色金属研究院陕西西安710016 ALD真空技术股份公司德国Hanau D63450

电子束冷床熔炼工艺作为一种新熔炼技术,可应用于生产航空发动机转动件用优质钛合金和回收残钛。利用500kW电子束冷床熔炼设备,研究了熔炼速度与Ti64合金铸锭化学成分和TiN夹杂溶解速度的关系。熔炼速度分别为70,100,140kg/h时,Al挥发... 详细信息

电子束冷床熔炼工艺作为一种新熔炼技术,可应用于生产航空发动机转动件用优质钛合金和回收残钛。利用500kW电子束冷床熔炼设备,研究了熔炼速度与Ti64合金铸锭化学成分和TiN夹杂溶解速度的关系。熔炼速度分别为70,100,140kg/h时,Al挥发损失分别为22%、16%、12%。经超声探伤,在熔炼电极中加入的TiN夹杂能够全部消除。所熔炼的铸锭外部是均匀的柱状晶粒,心部是细小的晶粒。

关键词：钛电子束冷床熔炼铝挥发 TiN夹杂真空熔炼