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Multi-exponential model to describe pressure-dependent p-and S-wave velocities and its use to estimate the crack aspect ratio

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Journal of Rock Mechanics and geotechnical Engineering 2022年第2期14卷 385-395页

作者： Mihály Dobróka Norbert péter Szabó Tünde Edit Dobróka Mátyás Krisztián Baracza Department of geophysics University of MiskolcMiskolc-Egyetemváros3515Hungary MTA-ME geoengineering Research group University of MiskolcMiskolc-Egyetemváros3515Hungary Research Institute of Applied Earth Sciences University of MiskolcMiskolc-Egyetemváros3515Hungary

We present new quantitative model describing the pressure dependence of acoustic p-and S-wave *** that a variety of individual mechanisms or defects(such as cracks,pore collapse and grain crushing)can contribute to the pressure-dependent change of the wave velocity,we order a characteristic pressure to all of them and allow a series of exponential terms in the description of the(pand S-waves)velocity-pressure *** estimate the parameters of the multi-exponential rock physical model in inversion procedures using laboratory measured p-and S-wave velocity *** is known,the conventional damped least squares method gives acceptable results only when one or two individual mechanisms are *** the number of exponential terms leads to highly nonlinear ill-posed inverse *** to this reason,we develop the spectral inversion method(SIM)in which the velocity amplitudes(the spectral lines in the characteristic pressure spectrum)are only considered as *** characteristic pressures(belonging to the velocity amplitudes)are excluded from the set of inversion unknowns,instead,they are defined in a set of fixed positions equidistantly distributed in the actual interval of the independent variable(pressure).Through this novel linear inversion method,we estimate the parameters of the multi-exponential rock physical model using laboratory measured p-and S-wave velocity *** characteristic pressures are related to the closing pressures of cracks which are described by well-known rock mechanical relationships depending on the aspect ratio of elliptical *** gives the possibility to estimate the aspect ratios in terms of the characteristic pressures.

关键词： Multi-exponential rock physical model Spectral inversion method(SIM) Crack aspect ratio Characteristic pressures

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老年胃溃疡出血患者再发出血的危险因素分析

中国烧伤创疡杂志 2024年第1期36卷 62-65页

作者：卞卡张巍巍许昌市中心医院消化内科河南许昌461000 许昌市中心医院胃肠外科河南许昌461000

目的探讨分析老年胃溃疡出血患者再发出血的相关危险因素。方法选取2020年3月至2022年3月许昌市中心医院收治的140例老年胃溃疡出血患者作为研究对象,收集患者性别、年龄、发病部位、胃溃疡长径、出血活动度、是否为胃溃疡A1期、是否合... 详细信息

目的探讨分析老年胃溃疡出血患者再发出血的相关危险因素。方法选取2020年3月至2022年3月许昌市中心医院收治的140例老年胃溃疡出血患者作为研究对象,收集患者性别、年龄、发病部位、胃溃疡长径、出血活动度、是否为胃溃疡A1期、是否合并幽门螺杆菌(Hp)感染、有无吸烟史、有无饮酒史、合并其他慢性疾病种类(≤2种、>2种)、是否进行消化内镜治疗、是否长期使用非甾体抗炎药(NSAIDs)等资料,并根据患者止血成功后1个月内是否再发出血将患者分为发生组与未发生组。多因素Logistic回归分析老年胃溃疡出血患者再发出血的危险因素。结果140例老年胃溃疡出血患者均于止血成功后随访1个月,随访过程中21例(150%)患者再发出血,设为发生组;119例(850%)患者未再发出血,设为未发生组。单因素分析结果显示,发生组胃溃疡A1期、Hp感染、未进行消化内镜治疗、长期使用NSAIDs的患者比例均明显高于未发生组(χ^(2)=4269、7381、7580、11836,p=0039、0007、0006、0001);多因素Logistic回归分析结果显示,胃溃疡A1期、Hp感染、未进行消化内镜治疗、长期使用NSAIDs是老年胃溃疡出血患者再发出血的独立危险因素(95%CI为1039~9660、1909~58707、0059~0585、1880~18559,p=0043、0007、0004、0002)。结论胃溃疡A1期、Hp感染、未进行消化内镜治疗、长期使用NSAIDs是老年胃溃疡出血患者再发出血的独立危险因素,临床应根据患者具体情况制定针对性干预措施,以降低再出血发生风险。

关键词：胃溃疡出血老年再出血消化内镜治疗幽门螺杆菌非甾体抗炎药危险因素

经支气管冷冻肺活检后按需手术肺活检对比即刻手术肺活检诊断间质性肺疾病(COLD研究):一项随机对照临床试验

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中华结核和呼吸杂志 2024年第9期47卷 826-826页

作者： kalverda ka Ninaber MK Wijmans L 阳胜朱娅琳肖奎不详中南大学湘雅二医院呼吸与危重症医学科中南大学呼吸疾病研究所湖南省呼吸与危重症疾病临床医学研究中心中南大学呼吸疾病诊疗中心长沙410000

背景:间质性肺疾病(ILD)的充分诊断对于临床决策和预后非常重要。大多数ILD患者可通过对临床和放射学数据的评估做出准确诊断,但还有相当一部分患者仍需进行肺活检。手术肺活检(SLB)是获取组织的最常用方法,但其发病率甚至死亡率都很高... 详细信息

背景:间质性肺疾病(ILD)的充分诊断对于临床决策和预后非常重要。大多数ILD患者可通过对临床和放射学数据的评估做出准确诊断,但还有相当一部分患者仍需进行肺活检。手术肺活检(SLB)是获取组织的最常用方法,但其发病率甚至死亡率都很高。最近,临床引入了经支气管冷冻肺活检,其不良反应较SLB少,但诊断率低于SLB。本研究旨在比较两种诊断策略:阶梯策略(经支气管冷冻肺活检,如果冷冻活检获得的信息不够,再进行SLB)与即刻SLB策略。方法:COLD研究是一项在荷兰6家医院开展的多中心、随机对照临床试验。该研究纳入了经多学科团队讨论评估有肺活检指征的ILD患者。以1∶1的比例将患者随机分配到阶梯策略或即刻SLB策略中,并从首次手术开始随访12周。本研究的治疗对患者、临床医生和病理学家均未设盲。主要研究终点是非预期的胸管引流,定义为经支气管冷冻肺活检后需要胸管引流,或SLB后胸管引流时间延长(>24 h)。次要研究终点是诊断率、住院时间、术后疼痛评分和严重不良事件,其中,严重不良事件包括研究期间患者出现死亡、危及患者生命、患者需再次入院或患者住院时长增加[经支气管镜检查超过2 d(1个夜晚),SLB超过4 d(3个夜晚)]。研究进行了改良的意向治疗分析。研究已在荷兰试验注册中心(NL7634)注册,现已结束。结果:在2019年4月8日至2021年10月24日期间,122例ILD患者接受了研究评估;55例患者被随机分配至阶梯组(n=28)或即刻SLB组(n=27);即刻SLB组有3例患者被排除。阶梯组的28例患者中有3例发生意外胸管引流(11%,95%CI:4%~27%),而即刻SLB组24例患者中有11例(46%,95%CI:2%~65%)在24 h内无法拔除胸管,绝对风险降低35%(11%~56%,p=0.0058)。在阶梯策略中,仅经支气管冷冻肺活检后的多学科团队诊断率为82%(64%~92%),在经支气管冷冻肺活检不确定后进行后续SLB时,诊断率增至89%(73%~96%)。在即刻SLB策略中,多学科团队的诊断率为88%(69%~97%)。阶梯组的总住院时间为1 d(IQR 1~1),而即刻SLB组为5 d(IQR 4~6)。阶梯组发生了1起(4%)严重不良事件,而即刻SLB组发生了12起(50%)严重不良事件。结论:在ILD诊断中,如果需要对肺组织进行评估,那么诊断策略应从经支气管冷冻肺活检开始,然后在经支气管冷冻肺活检不能得出诊断结论时进行SLB,这样似乎可显著减轻患者负担,缩短住院时间,且诊断率与即刻SLB相似。

关键词：间质性肺疾病支气管镜检查多学科团队患者负担病理学家肺活检临床决策诊断策略

A Registry-Based Observational Study on the Maternal and Fetal Outcomes of COVID-19 patients in Hong Kong,China

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Maternal-Fetal Medicine 2024年第3期6卷 156-163页

作者： Hillary HY Leung Teresa WL Ma Florrie NY Yu Meliza CW Kong Tsz Kin Lo pauline pL So Wing-Cheong Leung Wendy Shu ka Wang Cheung Sakita Moungmaithong Chi Chiu Wang Liona C.poon Department of Obstetrics and gynaecology The Chinese University of HongKongHong Kong 999077China Department of Obstetrics and gynaecology Queen Elizabeth HospitalHong Kong 999077China Department of Obstetrics and gynaecology United Christian HospitalHong Kong 999077China Department of Obstetrics and gynaecology Princess Margaret HospitalHong Kong 999077China Department of Obstetrics and gynaecology Tuen Mun HospitalHong Kong 999077China Department of Obstetrics and gynaecology Kwong Wah HospitalHong Kong 999077China Department of Obstetrics and gynaecology Pamela Youde Nethersole Eastern HospitalHong Kong 999077China Department of Obstetrics and gynaecology Queen Mary HospitalHong Kong 999077China

Objective:To report the clinical maternal and fetal outcomes of pregnant women with coronavirus disease 2019(COVID-19),along with any associated pregnancy complications,in Hong Kong,China,and to assess the impact of COVID-19 vaccination on these ***:This prospective registry-based observational study included pregnant women who were recruited through convenient sampling and had a laboratory-confirmed severe acute respiratory syndrome coronavirus 2 infection with a cycle threshold(Ct)value result available on admission to eight local hospitals in Hong Kong,*** on clinical symptoms,laboratory results,medical treatments,delivery timing and mode,and pregnancy complications were extracted from the Hospital Authority’s electronic medical record ***,fetal,and pregnancy outcomes were compared between unvaccinated pregnant women with COVID-19 and those who had received at least one dose of COVID-19 vaccine before *** continuous variables and categorical variables were analyzed using the Mann-Whitney U test and the pearson’s chi-squared test respectively.A p value less than 0.05 was considered statistically ***:A total of 164 pregnant women were included,of whom 78(47.56%)were ***-19 was diagnosed before 28 weeks’gestation in 30(18.29%),while 134(81.71%)were diagnosed at or after 28 weeks’***-two(37.80%)women received at least one dose of COVID-19 *** were no significant differences between vaccinated and unvaccinated groups in the time interval between COVID-19 diagnosis and delivery,the Ct value,and the gestational age at infection onset or delivery(p>0.05).The majority of women were symptomatic at diagnosis regardless of vaccination status 55(88.71%)in vaccinated group vs.78(76.47%)in unvaccinated group(p=0.052).Symptoms did not significantly differ between groups except for cough(62.90%vs.47.06%,p=0.049).The overall rate of severe COVID-19 in pregnant women was *** t

关键词： COVID-19 Maternal outcomes Fetal outcomes pregnancy complications Severe COVID-19

Reframing palliative Care:An East-West Integrative palliative Care Model

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Chinese Journal of Integrative Medicine 2021年第10期27卷 723-728页

作者： S.Anjani D.Mattai ka-Kit p.Hui Department of Medicine David Geffen School of MedicineUniversity of California Los AngelesCaliforniaUSA Center for East-West Medicine Department of MedicineDavid Geffen School of MedicineUniversity of California Los AngelesCaliforniaUSA

Convergence of principles of palliative care and integrative medicine has led to the introduction of the new practice of integrative palliative care in which integrative therapies(including mind-body modalities,traditional Chinese medicine,Ayurveda,and dietary supplements)are used to provide symptom management for patients who are dying or experiencing the sequelae of serious illness and its *** propose an East-West Integrative palliative care model using non-drug therapies,such as acupuncture,diet,exercise,and stress management that shift the paradigm from suppressing the symptoms of illness to addressing both the root cause of the symptoms and the imbalance and declining homeostatic reserve that perpetuate these *** whole-person model expands the reach of palliative care,prolonging a better quality of life and allowing the patient to maintain as many activities as possible by preventing symptoms and improving *** this approach we reframe the dialogue such that patients are"living better"rather than"dying better"when faced with serious illness or *** this article,we provide an overview of the principles of palliative care,integrative medicine,and the novel area of integrative palliative care,and propose an East-West integrative palliative care model that incorporates and broadens the scope of these existing approaches.

关键词： person-centered model palliative care integrative medicine traditional Chinese medicine acupuncture symptom management cost-effectiveness reframing healthcare

Interface formation energy,bonding,energy band alignment in α-NaYF4 related core shell models:For future multi-layer core shell luminescence materials

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Journal of Rare Earths 2017年第4期35卷 315-334页

作者：黄勃龙董浩 Wong ka-Leung 孙聆东严纯华 Department of Applied Biology and Chemical Technology The Hong Kong Polytechnic University Beijing National Laboratory for Molecular Sciences State Key Laboratory of Rare Earth Materials Chemistry and ApplicationsPKU-HKU Joint Laboratory in Rare Earth Materials and Bioinorganic ChemistryCollege of Chemistry and Molecular EngineeringPeking University Department of Chemistry Hong Kong Baptist University

To break through the bottle-neck of quantum yield in upconversion （UC） core-shell system, we elucidated that the energy transfer efficiency in core-shell system had an evident contribution from the charge transfer of interface with related to two factors：（i） band offsets and （2） binding energy area density. These two variables were determined by material intrinsic properties and core-shell thickness ratio. We further unraveled the mechanism of non-radiative energy transfer by charge transfer induced dipole at the inter- face, based on a quasi-classical derivation from F6rster type resonant energy transfer （FRET） model. With stable bonding across the interface, the contributions on energy transfer in both radiative and non-radiative energy transfer should also be accounted together in Auzel＇s energy transfer （ETU） model in core-shell system. Based on the discussion about interface bonding, band offsets, and forma- tion energies, we figured out the significance of interface bonding induced gap states （IBIgS） that played a significant role for influ- encing the charge transfer and radiative type energy transfer. The interface band offsets were a key factor in dominating the non-radiative energy transfer, which was also correlated to core-shell thickness ratio. We found that the energy area density with re- lated to core/shell thickness ratio followed the trend of Boltzman sigmoidal growth function. By the physical trend, this work contrib- uted a reference how the multi-layered core-shell structure was formed starting from the very beginning within minimum size. A route was paved towards a systematic study of the interface to unveil the energy transfer mechanism in core-shell systems.

关键词： interface band-offset core-shell energy-transfer rare earths

prognostic values of tumor endothelial markers in patients with colorectal cancer

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World Journal of gastroenterology 2005年第9期11卷 1283-1286页

作者： ka Rmali MCA puntis Wg Jiang Metastasis and Angiogenesis Research group University Department of Surgery

AIM: Tumor endothelial markers (TEMs) are a newly discovered family of endothelial markers associated with tumor specificangiogenesis. This study sought to examine the levels of expression (qualitatively and quantitatively)for TEMs in human colon ***: Human colorectal cancer tissues (n = 48)and normal background tissues (n = 31) were obtained after surgery. RNA was extracted from frozen sections for gene amplification. The expression of TEMs (TEM-1to TEM-8) was assessed using RT-pCR and their transcript levels were determined using real-time-quantitative pCR(Q-RT-pCR).RESULTS: TEM-1 (p = 0.01), TEM-7 (p = 0.04), TEM-7R(p= 0.03), TEM-8 (p = 0.001) significantly raised in colon cancer tissues compared with the levels detected in normal background tissues. The expressions of TEM-2 and TEM-6were found to be not significantly different between tumor tissues and normal tissues (p＞0.05). patients who had cancer penetrating into and through the muscularis propria of the bowel wall and developed nodal involvement(Dukes C) exhibited significantly higher levels of TEM -8compared to patients who were node negative (p＜0.05).TEM-7 and TEM-7R showed high level of transcripts in Dukes C, but they were not statistically ***: The level of the expression of TEM-1,TEM-7, TEM-7R and TEM-8 (but not TEM-2 and TEM-6)were associated with both nodal involvement and disease progression, and may therefore, have a prognostic value in colorectal cancer.

关键词： Colon cancer Angiogenesis Tumor endothelial markers Dukes stages

Effect of Using Israel Napier grass in Feed Ration on growth performance of Local Chicken of Cambodia

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Journal of Environmental Science and Engineering(B) 2024年第1期13卷 47-52页

作者： Sophea Rous Tola ka Sokha Thim Sath Keo Kouch Theng ka.pong Cheuteal Institute of Technology Prasat Sambour District 060403Kampong Thom ProvinceCambodia Faculty of Veterinary Medicine Royal University of AgriculturePhnom Penh 12400Cambodia

This study investigated the effect of Israel grass in feed formulation on growth performance of local *** study was conducted from October 2023 until January 2024 in ka.pong Chheutel Institute of *** CRD(Completely Randomized Design)was used with 4 treatments and 4 *** local chicks were purchased from local famer at 1 day old and kept in whole pen by feeding commercial *** 21 days old the total 320 chicks were allocated into experimental *** 4 feed formulas based on the level of Israel grass added such as 0,5%,7%and 9%,were called T1(control),T2,T3 and T4 *** result showed that body weight gain,feed intake,ADg(Average Daily gain)and FCR(Feed Conversion Ratio)in all treatments were not significantly different(p>0.05).However,there was strong correlation between living weight with carcass of al treatments,but no difference among carcass percentage of local chicken for all different diet in this *** conclusion,the Israel grass did not affect growth performance of local chickens and can be used to replace some expensive feed ingredient,such as rice bran.

关键词： Israel grass growth performance carcass local chickens

The Relationship Between Orthographic Awareness and Chinese Reading in Hong Kong’s Young CSL Learners

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ECNU Review of Education 2020年第4期3卷 678-693页

作者： Yu ka Wong Department of Curriculum and Instruction The Chinese University of Hong KongShatinHong Kong SARChina

purpose:This study investigates young Chinese as a second language(CSL)learners’Chinese character reading performance and its relationship with their orthographic *** is a pressing need to gain a better understanding of Hong Kong’s ethnic minority students’CSL acquisition,so that more effective instruction can be ***/Approach/Methods:A total of 157 Hong Kong ethnic minority CSL students in grade 4 were evaluated using a range of assessments:orthographic awareness in identifying and utilizing character components,listening comprehension for vocabulary terms and short texts,and reading Chinese character lists with single-and two-character ***:The students performed consistently across the two lists but made fewer errors when reading the two-character word list,most of which were *** regression analysis showed that the students’orthographic awareness contributed significantly to their character ***/Value:The findings suggest that orthographic awareness can help ethnic minority CSL learners improve their Chinese character reading *** classes provided for such students,and for CSL learners in general,should place greater focus on literacy training.

关键词： Chinese literacy Chinese as a second language Hong Kong’s ethnic minority students orthographic awareness