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Optimal Deep Canonically Correlated Autoencoder-Enabled Prediction Model for Customer Churn Prediction

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Computers, Materials & Continua 2022年第11期73卷 3757-3769页

作者： Olfat M.Mirza gJose Moses r.rajender E.Laxmi Lydia seifedine Kadry Cheadchai me-Ead Orawit Thinnukool Department of Computer science College of Computers and Information SystemsUmm Al-Qura UniversityMakkahSaudi Arabia Department of Computer science Engineering Malla Reddy Engineering College500100India Department of Computer science Engineering Lendi Institute of Engineering&TechnologyDenkada535005India Department of Computer science and Engineering Vignan’s Institute of Information TechnologyVisakhapatnam530049India Department of Applied Data science Noroff University CollegeNorway Program in statistics and Information Management Faculty of ScienceMaejo UniversityChiang Mai50290Thailand Department of Modern Management and Information Technology College of Arts Media and TechnologyChiang Mai UniversityChiang Mai50200Thailand

Presently,customer retention is essential for reducing customer churn in telecommunication *** churn prediction(CCP)is important to predict the possibility of customer retention in the quality of *** risks of customer churn also get essential,the rise of machine learning(ML)models can be employed to investigate the characteristics of customer ***,deep learning(DL)models help in prediction of the customer behavior based characteristic *** the DL models necessitate hyperparameter modelling and effort,the process is difficult for research communities and business *** this view,this study designs an optimal deep canonically correlated autoencoder based prediction(ODCCAEP)model for competitive customer dependent application *** addition,the O-DCCAEP method purposes for determining the churning nature of the *** O-DCCAEP technique encompasses preprocessing,classification,and hyperparameter ***,the DCCAE model is employed to classify the churners or ***,the hyperparameter optimization of the DCCAE technique occurs utilizing the deer hunting optimization algorithm(DHOA).The experimental evaluation of the O-DCCAEP technique is carried out against an own dataset and the outcomes highlighted the betterment of the presented O-DCCAEP approach on existing approaches.

关键词： Churn prediction customer retention deep learning machine learning archimedes optimization algorithm

Click and bioorthogonal hyaluronic acid hydrogels as an ultra-tunable platform for the investigation of cell-material interactions

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Bioactive Materials 2023年第6期24卷 438-449页

作者： Nathan Lagneau Pierre Tournier Boris Halgand François Loll Yves Maugars Jérôme guicheux Catherine Le Visage Vianney Delplace Nantes Université OnirisCHU NantesINSERMRegenerative Medicine and SkeletonRMeSUMR 1229F-44000France

The cellular microenvironment plays a major role in the biological functions of ***,biomaterials,especially hydrogels,which can be design to mimic the cellular microenvironment,are being increasingly used for cell encapsulation,delivery,and 3D culture,with the hope of controlling cell ***,much remains to be understood about the effects of cell-material interactions,and advanced synthetic strategies need to be developed to independently control the mechanical and biochemical properties of *** address this challenge,we designed a new hyaluronic acid(HA)-based hydrogel platform using a click and bioorthogonal strain-promoted azide-alkyne cycloaddition(sPAAC)*** approach facilitates the synthesis of hydrogels that are easy to synthesize and sterilize,have minimal swelling,are stable long term,and are *** provides bioorthogonal HA gels over an uncommonly large range of stiffness(0.5-45 kPa),all forming within 1-15 *** importantly,our approach offers a versatile one-pot procedure to independently tune the hydrogel composition(e.g.,polymer and adhesive peptides).Using this platform,we investigate the independent effects of polymer type,stiffness,and adhesion on the secretory properties of human adipose-derived stromal cells(hAsCs)and demonstrate that HA can enhance the secretion of immunomodulatory factors by hAsCs.

关键词： Hydrogels Click and bioorthogonal chemistry Hyaluronic acid mesenchymal stromal cells Cell-material interactions secretome

Impact loads generated by tandem cavitation bubble on solid wall

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Journal of Hydrodynamics 2022年第3期34卷 467-482页

作者： Nyo me Thet Naing Jaehyun Park seung-Ho Hyun rho-Taek Jung school of Naval Architecture and Ocean Engineering University of UlsanUlsanKorea school of Electrical Engineering University of UlsanUlsanKorea Foundation for Industry Cooperation University of UlsanUlsanKorea

Experiments on two cavitation bubbles,which are generated at the same instant,with three different sizes near solid wall are conducted and their impulses on the boundary are registered by polyvinylidene fluoride(PVDF)*** to being near the boundary,bubble interactions and deformed features are in contrast with those in infinite fluid *** this paper,five morphologies of bubble deformation during growth and collapse phases are observed by high-speed *** profiles are strongly influenced by inter-bubble distance(η),stand-off distance from boundary(γ),and bubble size *** of photographs coupled with sensor measurements enabled qualitative investigation of two bubble interactions on the *** sensor data acquisition,it is confirmed that lower bigger bubble with upper smaller bubble configuration produces highest impulses on the boundary compared with other vertical arrangements of the tandem cavitation bubble employed in this study.

关键词： Two bubbles spark-generated bubble impulse polyvinylidene fluoride(PVDF)

Events sourcing and Command Query responsibility segregation Based Fast Data Architecture

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Open Journal of Applied sciences 2023年第2期13卷 198-206页

作者： gérard Behou N’guessan Odilon Yapo Achiepo Jérôme Diako research and Digital Expertise Unit (UrEN) Virtual University of C&#244te d’Ivoire (UVCI) Abidjan Ivory Coast Lastic ESATIC Abidjan Ivory Coast

With the advent of Big Data, the fields of statistics and Computer science coexist in current information systems. In addition to this, technological advances in embedded systems, in particular Internet of Things technologies, make it possible to develop real-time applications. These technological developments are disrupting software Engineering because the use of large amounts of real-time data requires advanced thinking in terms of software architecture. The purpose of this article is to propose an architecture unifying not only software Engineering and Big Data activities, but also batch and streaming architectures for the exploitation of massive data. This architecture has the advantage of making possible the development of applications and digital services exploiting very large volumes of data in real time;both for management needs and for analytical purposes. This architecture was tested on COVID-19 data as part of the development of an application for real-time monitoring of the evolution of the pandemic in Côte d’Ivoire using PostgresQL, ELasticsearch, Kafka, Kafka Connect, NiFi, spark, Node-red and MoleculerJs to operationalize the architecture.

关键词： Architecture software Engineering Big Data Data Engineering real Time

Zinc oxide nano-enabled microfluidic reactor for water purification and its applicability to volatile organic compounds

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Microsystems & Nanoengineering 2018年第1期4卷 450-456页

作者： Imadeddine Azzouz Yamina ghozlane Habba Martine Capochichi-gnambodoe Frédéric Marty Jérôme Vial Yamin Leprince-Wang Tarik Bourouina UniversitéParis-Est ESIEE-ParisESYCOM EA 25522 Boulevard Blaise Pascal93162 Noisy-le-GrandFrance UniversitéParis-Est UPEMESYCOM EA 25525 Boulevard Descartes77420 Champs sur MarneFrance LsABM CNRS UMR 8231ESPCI ParisTech-PSL Research University10 Rue Vauquelin75005 ParisFrance

This paper reports fast and efficient chemical decontamination of water within a tree-branched centimeter-scale microfluidic *** microreactor integrates Zinc oxide nanowires(ZnO NWs)in situ grown acting as an efficient photocatalytic nanomaterial *** growth of ZnO NWs within the microfluidic chamber brings this photocatalytic medium at the very close vicinity of the water flow path,hence minimizing the required interaction time to produce efficient purification *** demonstrate a degradation efficiency of 95%in o5 s of residence time in one-pass *** to our estimates,it becomes attainable using microfluidic reactors to produce decontamination of merely 1 l of water per day,typical of the human daily drinking water *** conduct our experiments,we have chosen a laboratory-scale case study as a seed for addressing the health concern of water contamination by volatile organic compounds(VOCs),which remain difficult to remove using alternative decontamination techniques,especially those involving water *** contaminated water sample contains mixture of five pollutants:Benzene;Toluene;Ethylbenzene;m–p Xylenes;and o-Xylene(BTEX)diluted in water at 10 *** of *** was analytically monitored in a selective manner until it falls below 1 *** each of the five pollutants,corresponding to the maximum contaminant level(MCL)established by the Us Environmental Protection Agency(EPA).We also report on a preliminary study,investigating the nature of the chemical by-products after the photocatalytic VOCs degradation process.

关键词： microfluidic reactor water purification zinc oxide nanowires volatile organic compounds(VOCs) Benzene,Toluene,Ethylbenzene,m-p Xylenes,o-Xylene(BTEX)

The microbiome and autoimmunity: a paradigm from the gut–liver axis

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Cellular & Molecular Immunology 2018年第6期15卷 595-609页

作者： Bo Li Carlo selmi ruqi Tang me gershwin Xiong Ma Division of gastroenterology and Hepatology Key Laboratory of Gastroenterology and HepatologyMinistry of HealthState Key Laboratory for Oncogenes and Related GenesRenji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai Institute of Digestive DiseaseShanghai 200001China Division of rheumatology and Clinical Immunology Humanitas Research HospitalRozzanoItaly BIOmeTrA Department University of Milan MilanItaly Division of rheumatology Department of MedicineAllergy and Clinical ImmunologyUniversity of California at DavisDavisCAUSA

Microbial cells significantly outnumber human cells in the body,and the microbial flora at mucosal sites are shaped by environmental factors and,less intuitively,act on host immune responses,as demonstrated by experimental data in germ-free and gnotobiotic *** understanding of this link stems from the established connection between infectious bacteria and immune tolerance breakdown,as observed in rheumatic fever triggered by streptococci via molecular mimicry,epitope spread and bystander *** availability of high-throughput techniques has significantly advanced our capacity to sequence the microbiome and demonstrated variable degrees of dysbiosis in numerous autoimmune diseases,including rheumatoid arthritis,type 1 diabetes,multiple sclerosis and autoimmune liver *** remains unknown whether the observed differences are related to the disease pathogenesis or follow the therapeutic and inflammatory changes and are thus mere *** fact,there are only limited data on the molecular mechanisms linking the microbiota to autoimmunity,and microbial therapeutics is being investigated to prevent or halt autoimmune *** a putative mechanism,it is of particular interest that the apoptosis of intestinal epithelial cells in response to microbial stimuli enables the presentation of self-antigens,giving rise to the differentiation of autoreactive Th17 cells and other T helper *** comprehensive review will illustrate the data demonstrating the crosstalk between intestinal microbiome and host innate and adaptive immunity,with an emphasis on how dysbiosis may influence systemic *** particular,a gut–liver axis involving the intestinal microbiome and hepatic autoimmunity is elucidated as a paradigm,considering its anatomic and physiological connections.

关键词： autoimmunity autoimmune liver disease dysbiosis microbiome

New Insights on the mechanism of Thermal Cleavage of Unsaturated Bicyclic Diaziridines： A DFT study

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Chinese Journal of Chemistry 2011年第7期29卷 1347-1352页

作者： Arshadi, s. Bekhradnia, A. r. Ahmadi, s. Karami, A. r. Pourbeyram, s. Department of Chemistry Payame Noor University Tehran Iran Pharmaceutical sciences research Center Department of Medicinal Chemistry Mazandaran University of Medical Sciences Sari Iran shahid rajaee Teacher Training University Tehran Iran

A DFT calculations are carried out at UB3LYP/6-311＋＋g （3df, 2p） levels of theory to study electrocyclic thermal cleavage of four （r） derivatives of unsaturated bicyclic diaziridines, Ix-r, to produce corresponding （Z） and （E） azomethine imides （2X-Z, 2X-E, 3X-Z and 3X-E）, where X=H, me, t-Bu and Ph. Cleavage of 1X-r series to form the most stable 3X-Z product, （path 2） is found the favored procedure because of delocalized negative charge on five atoms and lower steric effect in related transition state. According to IrC calculations in paths 1 and 2, C6--N1 bond is cleaved before the rate determinating step （transition state）. The stability of unsaturated bicyclic diaziridines and their corresponding （Z） and （E） azomethine imides is in the following order in gas phase and chloroform, tetrahydrofuran, and acetone solvents： 3X-Z〈3X-F〈2X-Z 〈2X-E 〈 1X-r 〈 1X-s.

关键词： unsaturated bicyclic diaziridines azomethine imides electrocyclic thermal cleavage conrotatory motion molecular modeling conformational analysis

Optical Nanoimpacts of Dielectric and metallic Nanoparticles on gold surface by reflectance Microscopy: Adsorption or Bouncing?

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Journal of Analysis and Testing 2019年第2期3卷 175-188页

作者： Jean-François Lemineur Talia Jane stockmann Jérôme Médard Claire smadja Catherine Combellas Frédéric Kanoufi Universitésorbonne Paris Cité UniversitéParis DiderotITODYSCNRS UMR 708615 rue J.A.de Baïf75013 ParisFrance Present Address:memorial University of Newfoundland Chemistry Department283 Prince Philip Dr.St.John’sNL A1B 3X7Canada Faculty of Pharmacy University Paris-SudCNRS UMR 86125 rue J.B.Clément92296 Châtenay-MalabryFrance

Optical modeling coupled to experiments show that a microscope operating in reflection mode allows imaging,through solutions or even a microfluidic cover,various kinds of nanoparticles,NPs,over a(reflecting)sensing surface,here a gold(Au)*** modeling suggests that this configuration enables the interferometric imaging of single NPs which can be characterized individually from local change in the surface *** interferometric detection improves the optical limit of detection compared to classical configurations exploiting only the light scattered by the *** method is then tested experimentally,to monitor in situ and in real time,the collision of single Brownian NPs,or optical nanoimpacts,with an Au-sensing ***,mimicking a microfluidic biosensor platform,the capture of 300 nm FeOx maghemite NPs from a convective flow by a surface-functionalized Au surface is dynamically ***,the adsorption or bouncing of individual dielectric(100 nm polystyrene)or metallic(40 and 60 nm silver)NPs is observed directly through the *** influence of the electrolyte on the ability of NPs to repetitively bounce or irreversibly adsorb onto the Au surface is *** such visualization mode of single-NP optical nanoimpacts is insightful for comprehending single-NP electrochemical studies relying on NP collision on an electrode(electrochemical nanoimpacts).

关键词： reflection microscopy single nanoparticle sensor Adsorption silver Polystyrene

Current status and prospects of clinical proteomics studies on detection of colorectal cancer:Hopes and fears

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World Journal of gastroenterology 2006年第41期12卷 6594-6601页

作者： me de Noo rAEM Tollenaar AM Deelder LH Bouwman Department of surgery Leiden University Medical CenterLeidenThe Netherlands Biomolecular Mass spectrometry Unit Department of ParasitologyLeiden University Medical CenterLeidenThe Netherlands

Colorectal adenocarcinoma （CrC） is the third most common type of cancer and the fourth most frequent cause of death due to cancer worldwide. given the natural history of CrC, early diagnosis appears to be the most appropriate tool to reduce disease-related mortality. A field of recent interest is clinical proteomics, which was reported to lead to high sensitivity and specificities for early detection of several solid tumors. This emerging field uses mass spectrometry-based protein profiles/patterns of easy accessible body fluids to distinguish cancer from non-cancer patients. These discrepancies may be a result of：（i） proteins being abnormally produced or shed and added to the serum proteome, （2） proteins clipped or modified as a consequence of the disease process, or （3） proteins subtracted from the proteome owing to disease-related proteolytic degradation pathways. Therefore, protein pattern diagnostics would provide easy and reliable tools for detection of cancer. This paper focuses on the current status of clinical proteomics research in oncology and in colorectal cancer especially, and will reflect on pitfalls and fears in this relatively new area of clinical medicine, which are reproducibility issues and pre-analytical factors, statistical issues, and identification and nature of discriminating proteins/peptides.

关键词： Proteomics Colorectal cancer Protein profiling Diagnosis Biomarkers statistical issues