检索结果-南通市图书馆

SARS-CoV-2 Variants of Concern Delta:a great challenge to prevention and control of COVID-19

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2021年第10期6卷 2942-2944页

作者： Maochen Li fuxing lou Huahao Fan College of Life Science and Technology Beijing University of Chemical TechnologyBeijingChina

Recently,three groups evaluated the effects of monoclonal antibodies,convalescent serum,and vaccines on Delta variant,^(1-3)which leads to concerns about the effectiveness of current vaccines to the upcoming SARS-CoV-2 *** World Health Organization(WHO)has designated SARS-CoV-2 variants Alpha(B.1.1.7),Beta(B.1.351),Gamma(P.1),and Delta(B.1.617.2)as Variants of Concern(VOC),among which Delta variant with remarkable transmission and immune escape ability has attracted great attentions.

关键词： Delta prevention COV

SARS-CoV-2 variant Omicron:currently the most complete“escapee”from neutralization by antibodies and vaccines

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2022年第2期7卷 343-345页

作者： Maochen Li fuxing lou Huahao Fan College of Life Science and Technology Beijing University of Chemical Technology100029BeijingChina

On December 23,2021,five groups published their research results of clinical-approved monoclonal antibodies,convalescent serum,and vaccine serum against B.1.1.529(Omicron)on Nature.1–5 As a SARS-CoV-2 variant of concern(VOC),variant Omicron named by World Health Organization(WHO)with more mutations possesses the increased immune escape ability than all previous reported circulating variants,which has attracted extensive attention all over the world(Fig.1a).

关键词： antibodies vaccine vaccines

稳态磁场对激光熔注球形WC颗粒分布的影响机理研究

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

机械工程学报 2021年第1期57卷 240-248页

作者：胡勇王梁娄复兴夏洪超张群莉姚建华浙江工业大学激光先进制造研究院杭州310014 浙江工业大学高端激光制造装备省部共建协同创新中心杭州310014 浙江工业大学特种装备制造与先进加工技术教育部重点实验室杭州310014

利用稳态磁场对金属流体的粘滞效应,在316L不锈钢基体上制备颗粒梯度分布的WC/316L复合涂层。为研究稳态磁场对激光熔注球形WC颗粒分布的影响机理,建立了考虑固液相变、流动以及洛伦兹力的熔注熔池多物理场模型,分析稳态磁场对流场,洛... 详细信息

利用稳态磁场对金属流体的粘滞效应,在316L不锈钢基体上制备颗粒梯度分布的WC/316L复合涂层。为研究稳态磁场对激光熔注球形WC颗粒分布的影响机理,建立了考虑固液相变、流动以及洛伦兹力的熔注熔池多物理场模型,分析稳态磁场对流场,洛伦兹力分布以及等效黏度的影响。采用多颗粒动力学模型与熔池模型耦合计算,研究稳态磁场对熔池颗粒运动的影响。实验与仿真结果均证实,随着磁场强度从0 T增大至1.2 T,WC颗粒集中分布在复合涂层表层的趋势增大。分析结果表明:稳态磁场可有效增加熔池流体的等效黏度,使得颗粒在熔池中对流体的跟随性增强;同时,外加稳态磁场可以明显抑制熔池Marangoni对流,进一步降低了颗粒的运动能力,使得颗粒难以运动至熔池内部,大部分增强颗粒集中于熔池上表层。

关键词：激光熔注稳态磁场熔池复合涂层多物理场

在线全文

学校读者我要写书评

暂无评论

鱿鱼足静电裹粉装置设计与参数试验优化

农业机械学报 2018年第5期49卷 390-396页

作者：邹福星楼建忠朱盘安李建平季明东何相逸浙江大学生物系统工程与食品科学学院杭州310058 中原工学院纺织学院郑州451191 浙江机电职业技术学院机械工程学院杭州310053 温州科技职业学院农业与生物技术学院温州325006

针对鱿鱼足人工裹粉时粉料容易受潮、利用率低,且鱿鱼足表面粉层分布不均匀、容易漏裹的问题,提出利用气流输送粉料、施加高压静电使粉料带上电荷进行鱿鱼足裹粉的方法。为研究相对湿度和静电电压对鱿鱼足裹粉速度和裹粉量的影响,以及... 详细信息

针对鱿鱼足人工裹粉时粉料容易受潮、利用率低,且鱿鱼足表面粉层分布不均匀、容易漏裹的问题,提出利用气流输送粉料、施加高压静电使粉料带上电荷进行鱿鱼足裹粉的方法。为研究相对湿度和静电电压对鱿鱼足裹粉速度和裹粉量的影响,以及鱿鱼足表面粉料的附着效果,设计了试验装置,设置了40%、60%、80%3种相对湿度和0、30、60、90 k V 4种静电电压,进行了不同相对湿度和静电电压下的鱿鱼足静电裹粉试验和离心式附着效果测试试验。结果表明:施加高压静电可提高裹粉速度和裹粉量;相对湿度为40%、静电电压为30 k V时,裹粉速度最快、裹粉量最大;相对湿度为60%时,提高静电压可显著提高裹粉速度和裹粉量;相对湿度为80%时,不同静电压下裹粉速度和裹粉量差异不明显;0~1 s内裹粉量增加最快,相对湿度为40%时,在0~0.5 s时间段内裹粉量的增加最显著;在相对湿度为60%、静电电压60 k V时进行鱿鱼足裹粉,粉料的附着效果较好。

关键词：鱿鱼足裹粉附着效果高压静电离心试验

激光增材制造过程中激光与粉末的相互作用研究现状

在线全文

学校读者我要写书评

暂无评论

中国表面工程 2021年第2期34卷 1-12页

作者：叶福兴王永辉娄智天津大学材料科学与工程学院天津市现代连接技术重点实验室天津300072

激光增材制造是通过激光加热熔化粉末或丝材并逐层叠加而形成所需工件的一种增量制造技术。该技术涉及非常复杂的非平衡物理和化学冶金过程,在加工过程中易产生非平衡组织和晶粒取向。激光与粉末的相互作用过程是整个加工过程中最为重... 详细信息

激光增材制造是通过激光加热熔化粉末或丝材并逐层叠加而形成所需工件的一种增量制造技术。该技术涉及非常复杂的非平衡物理和化学冶金过程,在加工过程中易产生非平衡组织和晶粒取向。激光与粉末的相互作用过程是整个加工过程中最为重要的部分,系统总结激光与粉末的相互作用对于增进对激光增材制造技术的理解,进而提升工件性能具有重要的意义。按照送粉式与铺粉式激光增材制造两种加工方式,分析了激光能量的衰减、粉末颗粒温度的上升以及激光-粉末-熔池的相互作用,综述了激光与粉末相互作用的研究现状。

关键词：激光增材制造激光粉末相互作用激光-粉末-熔池

Progress in magnetic resonance imaging of the glymphatic system

在线全文

学校读者我要写书评

暂无评论

Magnetic Resonance Letters 2024年第4期4卷 1-11页

作者： Jinhao Lyu Xinyu Wang Qi Duan Wanbing Wang Runze Li Xiaoyu Wang Xin lou Department of Radiology Chinese PLA General Hospital/Chinese PLA Medical School28 Fuxing RoadBeijing100853China

The glymphatic system(GS)is a newly discovered brain *** discovery improves our understanding of brain fluid flow and waste removal paths and provides an anatomical basis for the flow of cerebral interstitial fluid(ISF)and cerebrospinal fluid(CSF).GS occurs through a normal exchange within perivascular space(PVS),facilitating the elimination of metabolic wastes generated by nerve cells from the ***,the GS is mainly responsible for the removal of metabolic *** GS activity has been observed to be associated with central nervous system disorders such as cerebral small vessel disease(CSVD)and neurodegenerative *** activity is expected to be an indicator for diagnosing diseases and predicting their *** review introduces the magnetic resonance imaging(MRI)technology related to the GS suitable for clinical use and the difference in the system's activity in normal and abnormal *** a summary of previous research,imaging methods suitable for monitoring the activity of the GS in the clinic were proposed,and their diagnostic effect on different brain disorders was *** review aims to clarify ideas for the clinical translation of basic research focusing on GS and provide future clinical research directions and perspectives.

关键词： Glymphatic system Neurofluid MR imaging Physiological status Central nervous system disorders

同方期刊数据库

Interpretations and comments for expert consensus on the diagnosis and treatment of heat stroke in China

在线全文

学校读者我要写书评

暂无评论

Military Medical Research 2020年第3期7卷 371-372页

作者： Shu-Yuan Liu Qian Wang Yun-Peng lou Yan Gao Bo Ning Qing Song Hai-Ling Li Medical School of Chinese PLA No.28 of Fuxing RoadBeijing 100853China Emergency Department Sixth Medical CenterChinese PLA General HospitalNo.6 of Fucheng RoadBeijing 100048China Emergency Department Third Medical CenterChinese PLA General HospitalNo.69 of Yongding RoadBeijing 100039China Department of Intensive Care Unit No.971 Hospital of the People’s Liberation Army NavyNo.22 Minjiang RoadQingdao 266071China Emergency Department General Hospital of Northern Theater Command of Chinese PLANo.83 of Wenhua RoadShenyang 110016China Department of Intensive Care Unit Air Force Medical Center of ChinaNo.30 of Fucheng RoadBeijing 100142China

Heat stroke is the most severe type of heat illness,it is often accompanied by severe multiorgan damage and has a high fatality *** January 2020,based on new research evidence and the experiences of Chinese experts in heat stroke,the Expert Group of Heat Stroke Prevention and Treatment of the Chinese People’s Liberation Army(PLA)and the Professional Committee of Critical Care Medicine of the Chinese PLA jointly issued a new Expert Consensus on the Diagnosis and Treatment of Heat Stroke in *** article aims to interpret and supplement the major updates to the new consensus.

关键词： Heat stroke Definition Diagnosis Treatment Targeted temperature management

Effects of a closed-loop system against SARS-CoV-2 at the Beijing 2022 Olympic Winter Games:a descriptive and modeling study

在线全文

学校读者我要写书评

暂无评论

World Journal of Emergency Medicine 2023年第6期14卷 471-476页

作者： Rong Xiong Jieping Zhou Wenning Li Jie Liu Jing lou Sijia Tian Huixin Lian Shengmei Niu Luxi Zhang Wenhang Li Jinjun Zhang Emergence Medical Service Group for Beijing 2022 Winter Olympic Games Beijing Emergency Medical CenterBeijing 100031China Department of Neurology Beijing Fuxing HospitalCapital Medical UniversityBeijing 100038China Aerospace Information Research Institute Chinese Academy of SciencesBeijing 100094China Department of General Surgery Beijing Tongren HospitalCapital Medical UniversityBeijing 100730China Games Services Department Beijing Organizing Committeefor the 2022 Olympic and Paralympic Winter Games

BACKGROUND:To assess the efficacy of the epidemic prevention measures of the“closed-loop”system adopted by the Beijing 2022 Olympic Winter Games(BOWG).METHODS:We retrospectively collected and analyzed information,including age,sex,nationality,vaccination status,date of diagnosis,and date of entry,from 280 SARS-CoV-2-positive individuals identified during the BOWG.A susceptibility-exposed-infectious-remove model was employed to evaluate the effectiveness of epidemic prevention strategies on controlling the spread of SARS-CoV-2 under different scenarios during the ***:Regarding SARS-CoV-2-positive cases,97.9%were imported,and 96.4%were *** median age was 37 years(range:29–47 years),and 73.9%were male,with the majority of cases being broadcasters and European *** vaccination status,93.5%were fully vaccinated,and six cases were considered to have been infected in the closed-loop system during the *** that the BOWG adopted a semi-closed-loop management system,the cumulative number of confirmed cases would be 1,137 for quick quarantine measures(3 d later)implemented and 5,530 for delayed quarantine measures(9 d later)*** modeling revealed that stringent pandemic prevention measures and closed-loop management effectively controlled the spread of SARS-CoV-2 during the ***:Imported cases are considered the main risk factor for SARS-CoV-2 transmission during mass gatherings,but a comprehensive closed-loop system could minimize transmission among attendees and general personnel.

关键词： Olympic Winter Games Emergency medical service SARS-CoV-2 COVID-19 Infectious disease Transmission

肺超声彗星尾征对急性呼吸窘迫综合征血管外肺水判定与评估

在线全文

学校读者我要写书评

暂无评论

中国实用内科杂志 2017年第8期37卷 722-725页

作者：赵振姜利朱波王美平娄然首都医科大学附属复兴医院北京100038

目的探索肺超声评分(LUS)判定血管外肺水指数(EVLW)的敏感度和特异度。方法入选2012年6月至2014年12月首都医科大学附属复兴医院重症医学科连续收治的急性呼吸窘迫综合征(ARDS)患者21例,于入ICU第1个24 h内记录患者一般临床特征,完善胸... 详细信息

目的探索肺超声评分(LUS)判定血管外肺水指数(EVLW)的敏感度和特异度。方法入选2012年6月至2014年12月首都医科大学附属复兴医院重症医学科连续收治的急性呼吸窘迫综合征(ARDS)患者21例,于入ICU第1个24 h内记录患者一般临床特征,完善胸部CT检查,并于入ICU第1、2、3天分别行床旁X线胸片、肺超声及判定与脉搏指示持续心排量监测(PiCCO)3者检查时间相隔<2 h;同时设立非ARDS患者为对照组,于24h内完成肺超声、胸部CT及胸片检查。结果 LUS与PiCCO测定的EVLWI呈显著线性相关(r=0.927,P<0.01);LUS与X线胸片评分之间呈显著正相关(r=0.720,P<0.01)。肺超声判定ELVW的ROC曲线下面积为0.924(P<0.01),cut-off值为12.5,其敏感度和特异度分别为0.857和0.600;床旁X线胸片判定ELVW的ROC曲线下面积为0.732(P=0.019),cut-off值为14.0,其敏感度和特异度分别为0.619和0.667。结论 LUS具有较高的敏感度和特异度及可重复性用以定性及定量判定ARDS患者EVLW。

关键词：急性呼吸窘迫综合征肺超声彗星尾血管外肺水床旁胸片定量