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An integrated spatial planning of the mountainous landscapes for ski sports in a case area at the eastern Türkiye

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Journal of Mountain Science 2024年第3期21卷 754-767页

作者： SATIR Onur TOSUN busra COSKUN OZYOL funda OZDEMIR Omer Faruk bERbEROGLU Suha Dept.of Landscape Architecture Van Yuzuncu Yil UniversityVan 65090Türkiye School of Physical Education&Sports Van Yuzuncu Yil UniversityVan 65090Türkiye Van Yuzuncu Yil University Dept.of Architecture&Urban Planning Van 65090Türkiye Dept.of Remote Sensing&GIS Cukurova UniversityAdana 01330Türkiye

Mountainous regions have disadvantages in economic development because of harsh physical and climatic ***,winter tourism activities are one of the key components for supporting economic development in the *** a ski resort area supports direct and indirect employment in a region,and it stops immigration from mountainous regions to other *** research aimed to assess the potential ski areas using a multi criteria evaluation technique in the Van region which is located in the eastern part of Tü*** this context,snow cover duration,sun effect,slope,slope length,elevation,population density,distance from main roads and lake visibility were used as input factors in the decision making *** factor was standardized using a fuzzy technique based on existing well-known ski centers in Tü*** weight of inputs was defined by applying a survey to the professional *** most important factors were detected as transportation opportunities and snow covers whereas,the least important factors were elevation and population ***,lake visibility was very important to make a difference from other existing facilities in the ***,it was included as constraints and lake visible areas were extracted at the final stage of the *** ski areas were mapped in three levels as professional,intermediate and beginner *** of the suitable areas was selected as a sample projection and for the 3D simulation of the ski investment *** costs and benefits were *** was found that a ski tourism area investment can be amortized in 3 years in the region.

关键词： Winter sports and tourism Decision making 3D simulation and modelling Landscape planning GIS

Investigation of Fracture Strength of Current Post Materials (Peek, Fiber, Cast Metal) in Different Ferrule Conditions

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Open Journal of Stomatology 2024年第3期14卷 153-172页

作者： başak Topdaği funda bayindir Department of Prosthetic Dentistry Atatürk University Erzurum Türkiye

Aim: The fracture resistance of the post materials used nowadays significantly impacts the fracture type of the post material. The current study aimed to examine the impact of the fracture resistance of PEEK posts, whose use as a post material has not yet become widespread, on the fracture pattern that will occur. Materials and Methods: Sixty-six extracted upper central incisor human teeth were used in the study. Six groups of posts were produced from metal, fiber, and PEEK materials (n = 11). Afterward, the fracture resistance test was applied to the samples. Samples were classified according to fracture type as repairable or irreparable. The ANOVA and test were used in statistical analysis. Post-hoc tests were carried out using Tukey’s and Tamhane’s T2 tests. On the other hand, Pearson’s chi-square test and the Fisher-Freeman-Halton test were conducted for comparisons between categorical variables. The statistical significance level was accepted as p Results: According to the fracture resistance test results, the groups where metal personal posts were used displayed higher fracture resistance in comparison with all other groups. According to the results of the optical microscope examination, the incidence of repairable fractures was significantly higher in the PEEK post group with ferrule preparation (p 0.05). Conclusion: In the absence of the ferrule effect, fractures are catastrophic, regardless of the material used. The use of PEEK as a post material contributes to keeping fractures at a repairable level.

关键词： Component Formatting Style Styling Insert

Management of cytomegalovirus infection after liver transplantation

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World Journal of Transplantation 2024年第3期14卷 30-39页

作者： Zeynep burcin Yilmaz funda Memisoglu Sami Akbulut Infectious Diseases and Clinical Microbiology Inonu University Faculty of MedicineMalatya 44280Türkiye Surgery and Liver Transplant Institute Inonu University Faculty of MedicineMalatya 44280Türkiye

Cytomegalovirus(CMV)infection is one of the primary causes of morbidity and mortality following liver transplantation(LT).based on current worldwide guidelines,the most effective strategies for avoiding post-transplant CMV infection are antiviral prophylaxis and pre-emptive ***-IgG serology is the established technique for pretransplant screening of both donors and *** clinical presentation of CMV infection and disease exhibits variability,prompting clinicians to consistently consider this possibility,partic-ularly within the first year post-transplantation or subsequent to heightened *** annual symposia to discuss CMV prevention and how treatment outcomes can be improved,evidence on the incorporation of immune functional tests into clinical practice is presented,and the results of studies with new antiviral treatments are *** there are ongoing studies on the use of letermovir and maribavir in solid organ transplantation,a consensus reflected in the guidelines has not been *** the most appro-priate strategy at the individual level appears to be the key to enhancing *** prevention strategies reduce the risk of CMV disease,the disease can still occur in up to 50%of high-risk patients.A balance between the risk of infection and disease development and the use of immunosuppressants must be considered when talking about the proper management of CMV in solid organ transplant *** objective of this study was to establish a compre-hensive framework for the management of CMV in patients who have had LT.

关键词： Liver transplantation Cytomegalovirus Antiviral prophylaxis Preemptive treatment Valganciclovir Ganciclovir

A hesitant fuzzy linguistic terms set-based AHP-TOPSIS approach to evaluate ERP software packages

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International Journal of Intelligent Computing and Cybernetics 2021年第1期14卷 54-77页

作者： Zeki Ayag funda Samanlioglu Kadir Has University IstanbulTurkey

Purpose–In this paper,two popular multiple-criteria decision-making(MCDM)methods with hesitant fuzzy logic approach;hesitant fuzzy analytic hierarchy process(hesitant F-AHP)and hesitant fuzzy the technique for order preference by similarity to ideal solution(HF-TOPSIS)are integrated as HF-AHP-TOPSIS to evaluating a set of enterprise resource planning(ERP)alternatives and rank them by weight to reach to the ultimate one that satisfies the needs and expectations of a ***/methodology/approach–Selecting the best ERP software package among the rising number of the options in market has been a critical problem for most companies for a long time because of the reason that an improper ERP software package might lead to many issues(*** loss,increased costs and a loss of market share).On the other hand,finding the best ERP alternative is a comprehensive MCDM problem in the presence of a set of alternatives and several potentially competing quantitative and qualitative ***–In this integrated approach,the hesitant F-AHP is used to determine the criteria weights,as the hesitant F-TOPSIS is utilized to rank ERP package *** proposed approach was also validated in a numerical example that has five ERP package alternatives and 12 criteria by three decision-makers in order to show its applicability to potential readers and *** limitations/implications–If the number of the alternatives and criteria are dramatically increased beyond reasonable numbers,the reaching to final solution will be so difficult because of the great deal of fuzzy based ***,the number of criteria and alternatives should be at reasonable *** implications–The proposed approach was also validated in a illustrated example with the five ERP package options and 12 criteria by the three decision-makers in order to show its applicability to potential readers and ***/value–Furthermore,in literature,to the b

关键词： Enterprise resource planning(ERP)package selection Hesitant fuzzy logic Multiple-criteria decision-making Analytic hierarchy process(AHP) Technique for order preference by similarity to ideal solution(TOPSIS)

Determination of epidemic parameters from early phase fatality data： A case study of the 2009 A（H1N1） pandemic in Europe

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International Journal of biomathematics 2018年第2期11卷 135-146页

作者： Ayse Humeyra bilge funda Samanlioglu Faculty of Engineering and Natural Sciences Kadir Has University Istanbul Turkey

This paper demonstrates that the susceptible-infected-removed （SIR） model applied to the early phase of an epidemic can be used to determine epidemic parameters reliably. As a case study, the SIR model is applied to the fatality data of the 2009 fall wave cycle of the A（H1N1） pandemic in 12 European countries. It is observed that the best estimates of the basic reproduction number R0 and the mean duration of the infection period l/r/ lie on a curve in the scatterplots, indicating the existence of a nearly-invariant quantity which corresponds to the duration of the epidemic. Spline interpolation applied to the early phase of the epidemic, an approximately 10-week period, together with a future control point in the stabilization region, is sufficient to estimate model parameters. The SIR model is run over a wide range of parameters and estimates of R0 in the range 1.2- 2.0 match the values in the literature. The duration of the infection period, 1/η is estimated to be in the range 2.0-7.0 days. Longer infection periods are tied to spatial characteristics of the spread of the epidemic.

关键词： Differential equations epidemic model influenza epidemiology A(H1N1) basic reproduction number,

Temperature and Thickness Effects on Electrical Properties of InP Films Deposited by Spray Pyrolysis

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Chinese Physics Letters 2009年第1期26卷 260-263页

作者： Refik Kayah Mehmet An Mustafa Oztas Metin bedir funda Aksoy Department of Physics Arts and Sciences Faculty Nigde University Nigde Turkey Department of Physics Arts and Sciences Faculty Erciyes University Kayseri Turkey Department if Physics and Engineering Engineering Faculty Gaziantep University Gaziantep Turkey

InP film samples are prepared by spray pyrolysis technique using aqueous solutions of InCl3 and Na2HPO4, which are atomized with compressed air as carrier gas onto glass substrates at 500° C with different thicknesses of the films. The structural properties of the samples are determined by x-ray diffraction （XRD）. It is found that the crystal structure of the InP films is polycrystalline hexagonal. The orientations of all the obtained films are along the c-axis perpendicular to the substrate. The electrical measurements of the samples are obtained by dc four-probe technique on rectangular-shape samples. The effects of temperature on the electrical properties of the InP films are studied in detail.

关键词： THIN-FILMS bEAM EPITAXY SOLAR-CELLS GROWTH-RATE DEPENDENCE

Neuroinflammation revisited through the microglial lens

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Neural Regeneration Research 2025年第7期20卷 1989-1990页

作者： Renato Socodato João b.Relvas Institute of Research and Innovation in Health(i3S)and Institute for Molecular and Cell biology(IbMC) University of PortoPortoPortugal Department of biomedicine Faculty of Medicine of the University of Porto(FMUP)PortoPortugal

Neuroimmunology is emerging as a pivotal field,shedding light on the intricate dialogues between the central nervous system(CNS)and the immune *** exploration is particularly significant in understanding microglia,the CNS’s innate immune cells,beyond the conventional conflation of“neuroinflammation”and“microglial activation.”This conflation has clouded the true complexity of these processes,potentially stalling scientific progress and the development of new *** challenge the long-standing perspectives that have oversimplified these interactions,advocating for a deeper exploration of the dynamic relationship between neuroinflammation and microglial *** dissecting specific molecular pathways,we aim to illuminate their elaborate roles in neuroinflammatory responses,especially in the context of Alzheimer’s disease(AD).Here,neuroinflammation is not merely a passive observer or a direct antagonist but a complex agent in the disease’s *** article calls for a significant paradigm shift towards an integrative,multi-omics approach to *** such a comprehensive framework is crucial for advancing our understanding of neuroinflammatory conditions and paving the way for targeted therapeutic strategies for brain diseases.

关键词： inflammation simplified activation

Clinical assessment of demineralization and remineralization surrounding orthodontic brackets with FluoreCam

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Asian Pacific Journal of Tropical biomedicine 2017年第4期7卷 373-377页

作者： bora Korkut Duygu Korkut funda Yanikoglu Dilek Tagtekin Department of Restorative Dentistry Faculty of DentistryMarmara UniversityHealth Science Campus Department of Orthodontics Faculty of DentistryMarmara UniversityHealth Science Campus

Objective: To determine quantitatively the amount of demineralization and the ability of commercially available products and an experimental cream to inhibit or reverse orthodontic related ***: A total of 20 patients who were 25–35 years old and having orthodontic treatment for 6–8 months were *** risk assessments were done for each patient and ones with "moderate risk" were *** with fixed orthodontic appliances were divided into 4 groups(5 patients each) including one control and 3 study *** patients used same toothpaste 2 times a day during the 3 weeks study *** to the toothpaste first study group used MI Paste Plus(GC, Tokyo, Japan), second study group used Remin Pro(Voco, Cuxhaven, Germany) and third group used an experimental remineralizing cream per day for 3 *** central and lateral incisors of each patient were examined by FluoreCam(Daraza Therametric Technologies, USA) *** examinations were performed at baseline and at the end of 1st, 2nd and 3rd ***: According to the FluoreCam measurements the control group showed significant amount of demineralization at the end of 3 weeks, moreover the amount of demineralization has gradually increased in *** the end of the study all 3 study groups showed significant amount of remineralization and the amount of remineralization for all the 3 study groups has gradually increased in *** the amount of remineralization for 3rd study group was lesser than the 1st and 2nd study *** remineralization amounts for the 1st and 2 nd study groups were determined to be ***: This study demonstrated that demineralization is measurable around orthodontic brackets and the demineralization can be completely inhibited and/or reversed by the use of commercially available remineralization products.

关键词： Demineralization Remineralization FluoreCam Orthodontic brackets MI Paste Plus Remin Pro

Treatment of type 2 diabetes mellitus in the elderly

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World Journal of Diabetes 2017年第6期8卷 278-285页

作者： funda Datli Yakaryilmaz Zeynel Abidin Oztürk Division of Geriatric Medicine Department of Internal MedicineFaculty of MedicineGaziantep University27100 SahinbeyGaziantepTurkey

The prevalence of type 2 diabetes is expected to increase gradually with the prolongation of population aging and life expectancy. In addition to macrovascular and microvascular complications of elderly patients of diabetes mellitus, geriatric syndromes such as cognitive impairment, depression, urinary incontinence,falling and polypharmacy are also accompanied by aging. Individual functional status in the elderly shows heterogeneity so that in these patients, there are many unanswered questions about the management of diabetes treatment. The goals of diabetes treatment in elderly patients include hyperglycemia and risk factors, as in younger patients. comorbid diseases and functional limitations of individuals should be taken into consideration when setting treatment targets. Thus, treatment should be individualized. In the treatment of diabetes in vulnerable elderly patients, hypoglycemia, hypotension, and drug interactions due to multiple drug use should be avoided. Since it also affects the ability to self-care in these patients, management of other concurrent medical conditions is also important.

关键词： Diabetes mellitus Oral antidiabetic drugs Insulin Elderly