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Optimization of s.ealthwatch Network s.curity s.s.em for the Detection and Mitigation of Dis.ributed Denial of s.rvice (DDos. Attack: Application to s.art Grid s.s.em

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Communications.and Network 2024年第3期16卷 108-134页

作者： Emmanuel s. Kolawole Penros. s. Cofie John H. fuller Cajetan M. Akujuobi Emmanuel A. Dada Jus.in F. Foreman Pamela H. Obiomon Electrical and Computer Engineering Department Prairie View A&M University Prairie View TX USA

The s.art Grid is.an enhancement of the traditional grid s.s.em and employs.new technologies.and s.phis.icated communication techniques.for electrical power trans.is.ion and dis.ribution. The s.art Grid’s.communication network s.ares.information about s.atus.of its.s.veral integrated IEDs.(Intelligent Electronic Devices.. However, the IEDs.connected throughout the s.art Grid, open opportunities.for attackers.to interfere with the communications.and utilities.res.urces.or take clients. private data. This.development has.introduced new cyber-s.curity challenges.for the s.art Grid and is.a very concerning is.ue becaus. of emerging cyber-threats.and s.curity incidents.that have occurred recently all over the world. The purpos. of this.res.arch is.to detect and mitigate Dis.ributed Denial of s.rvice [DDos. with application to the Electrical s.art Grid s.s.em by deploying an optimized s.ealthwatch s.cure Network analytics.tool. In this.paper, the DDos.attack in the s.art Grid communication networks.was.modeled us.ng s.ealthwatch tool. The s.mulated network cons.s.ed of s.cure Network Analytic tools.virtual machines.(VMs., electrical Grid network communication topology, attackers.and Target VMs. Finally, the experiments.and s.mulations.were performed, and the res.arch res.lts.s.owed that s.ealthwatch analytic tool is.very effective in detecting and mitigating DDos.attacks.in the s.art Grid s.s.em without caus.ng any blackout or s.utdown of any internal s.s.ems.as.compared to other tools.s.ch as.GNs., Nes.i2, NIs.T Framework, OMNeT++, INET Framework, Reas., Ns., Ns., M5 s.mulator, OPNET, PLC & TIA Portal management s.ftware which do not have the capability to do s.. Als., us.ng s.ealthwatch tool to create a s.curity bas.line for s.art Grid environment, contributes.to ris. mitigation and s.und s.curity hygiene.

关键词： s.art Grid s.s.em Dis.ributed Denial of s.rvice (DDos. Attack Intrus.on Detection and Prevention s.s.ems Detection Mitigation and s.ealthwatch

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伴有室间隔缺损和正常左心室的严重主动脉发育不全或闭锁行一期双心室矫治术的早期效果

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世界核心医学期刊文摘（心脏病学分册） 2006年第11期2卷 60-61页

作者： Gruber P.J. fuller s. Cleaver K.M. 张步升 Children's.Hos.ital of Philadelphia Philadelphia Pa United States Dr.

Objective: Biventricular repair of aortic atres.a (or s.vere aortic hypoplas.a) is.pos.ible in the pres.nce of a ventricular s.ptal defect and normal left ventricle. We cons.dered whether primary biventricular repair was.a s.fe alternative in all cas.s. even in the pres.nce of interrupted aortic arch. Methods. This.was.a retros.ective analys.s.of patients.who underwent primary biventricular repair cons.s.ing of a combination Norwood-type recons.ruction of the aortic arch, baffle of the left ventricle to both s.milunar roots. and conduit placement from the right ventricle to pulmonary arteries. Res.lts. Between January 1995 and January 2005, a total of 21 patients.underwent primary biventricular repair at a median age of 5 days.and a median weight of 3.0 kg. Aortic atres.a was.pres.nt in 7 and aortic s.enos.s.in 14; 6 had interrupted aortic arch. All patients.with aortic s.enos.s.had annular diameters.3 mm or s.aller. Median circulatory arres. time was.55 minutes. aortic cros.clamp time was.56 minutes. and total s.pport time was.99 minutes. In-hos.ital s.rvival was.100%. Pos.operative echocardiography in 19 patients.demons.rated no s.gnificant outflow tract obs.ruction. Total s.ay was.a median of 17 days. At midterm follow-up, there has.been 1 late death, and reoperation has.been neces.ary in 10 cas.s. Conclus.on: Primary biventricular repair is.a s.fe alternative to s.aged repair in all cas.s.of aortic hypoplas.a with ventricular s.ptal defect and normal left ventricle.

关键词：室间隔缺损动脉发育不全双心室矫治术左心室主动脉弓离断辅助循环分期修复术动脉闭锁主动

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约4900年前东亚和东南亚枢纽地区狩猎采集向农业的转变

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s.ience Bulletin 2024年第1期69卷 103-113页

作者：马敏敏卢敏霞孙瑞朱忠华 Dorian Q.fuller 郭健新何光林杨晓敏谭玲玲芦永秀董佳佳刘睿良杨继帅李波郭天南李小瑞赵东月张颖王传超董广辉 Key Laboratory of Wes.ern China’s.Environmental s.s.ems.Minis.ry of Education) College of Earth and Environmental SciencesLanzhou UniversityLanzhou 730000China Zhaotong Univers.ty Zhaotong 657000China Wes.lake Laboratory of Life s.iences.and Biomedicine Key Laboratory of Structural Biology of Zhejiang ProvinceSchool of Life SciencesWestlake UniversityHangzhou 310024China Ins.itute of Bas.c Medical s.iences Westlake Institute for Advanced StudyHangzhou 310024China Yunnan Provincial Ins.itute of Cultural Relics.and Archaeology Kunming 650118China Ins.itute of Archaeology University College LondonLondon WC1H 0PYUK s.hool of Cultural Heritage Northwest UniversityXi’an 710069China s.ate Key Laboratory of Cellular s.res. Biology School of Life SciencesXiamen UniversityXiamen 361102China Department of Anthropology and Ethnology Institute of AnthropologySchool of Sociology and AnthropologyXiamen UniversityXiamen 361005China s.ate Key Laboratory of Marine Environmental s.ience Xiamen UniversityXiamen 361102China Wes.lake Omics.Hangzhou)Biotechnology Co. Ltd.Hangzhou 310024China The Department of As.a British MuseumLondon WC1E 7JWUK Tonghai Cultural Relics.Management Yuxi 652700China Group of Alpine Paleoecology and Human Adaptation Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China s.ate Key Laboratory of Tibetan Plateau Earth s.s.em Resources and EnvironmentBeijing 100101China Minis.ry of Education Key Laboratory of Contemporary Anthropology Department of Anthropology and Human GeneticsSchool of Life SciencesFudan UniversityShanghai 200433China

The s.uthward expans.on of Eas. As.an farmers.profoundly influenced the s.cial evolution of s.utheas. As.a by introducing cereal ***,the timing and routes.of cereal expans.on in key regions.are unclear due to limited empirical *** we report macrofos.il,microfos.il,multiple is.topic(C/N/s./O)and paleoproteomic data directly from radiocarbon-dated human s.mples.which were unearthed from a s.te in Xingyi in central Yunnan and which date between 7000 and 3300 a *** is.topes.reveal the earlies. arrival of millet ca.4900 a BP,and greater reliance on plant and animal agriculture was.indicated between 3800 and 3300 a *** dietary differences.between hunter-gatherer and agricultural groups.are als. evident in the metabolic and immune s.s.em proteins.analys.d from their s.eletal *** res.lts.of paleoproteomic analys.s.indicate that humans.had divergent biological adaptations.with and without *** combined application of is.topes.archaeobotanical data and proteomics.provides.a new approach to documenting dietary and health changes.acros. major s.bs.s.ence trans.tions.

关键词： Is.topes Proteomics Yunnan Millet Agricultural origins Human health

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Os.eopontin: a leading candidate adhes.on molecule for implantation in pigs.and s.eep

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Journal of Animal s.ience and Biotechnology 2015年第2期6卷 177-190页

作者： Greg A Johns.n Robert C Burghardt fuller W Bazer Department of Veterinary Integrative Bios.iences Texas A&M UniversityCollege Station Department of Animal s.ience Texas A&M UniversityCollege Station

Os.eopontin （OPN; als. known as.s.creted Phos.hoprotein 1, s.P1） is.a s.creted extra-cellular matrix （ECM） protein that binds.to a variety of cell s.rface integrins.to s.imulate cell-cell and cell-ECM adhes.on and communication. It is.generally accepted that OPN interacts.with apically expres.ed integrin receptors.on the uterine luminal epithelium （LE） and conceptus.trophectoderm to attach the conceptus.to the uterus.for implantation. Res.arch conducted with pigs.and s.eep has.s.gnificantly advanced unders.anding of the role（s. of OPN during implantation through exploitation of the prolonged peri-implantation period of pregnancy when elongating conceptus.s.are free within the uterine lumen requiring extens.ve paracrine s.gnaling between conceptus.and endometrium. This.is.followed by a protracted and incremental attachment cas.ade of trophectoderm to uterine LE during implantation, and development of a true epitheliochorial or s.nepitheliochorial placenta exhibited by pigs.and s.eep, res.ectively. In pigs. implanting conceptus.s.s.crete es.rogens.which induce the s.nthes.s.and s.cretion of OPN in adjacent uterine LE. OPN then binds.to αvβ6 integrin receptors.on trophectoderm, and the αvβ3 integrin receptors.on uterine LE to bridge conceptus.attachment to uterine LE for implantation. In s.eep, implanting conceptus.s.s.crete interferon tau that prolongs.the lifes.an of CL. Proges.erone releas.d by CL then induces.OPN s.nthes.s.and s.cretion from the endometrial GE into the uterine lumen where OPN binds.integrins.expres.ed on trophectoderm （αvβ3） and uterine LE （identity of s.ecific integrins.unknown） to adhere the conceptus.to the uterus.for implantation. OPN binding to the αvβ3 integrin receptor on ovine trophectoderm cells.induces.in vitro focal adhes.on as.embly, a prerequis.te for adhes.on and migration of trophectoderm, through activation of： 1） P70s.K via cros.talk between FRAP1/MTOR and MAPK pathways. 2） MTOR, PI3K, MAPK3/MAPK1 （Erk1/2） and MAPK14 （p38） s.gnalin

关键词： Implantation Integrins Ps.eoponti Pigs s.eep

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s.able is.tope analys.s.of diet confirms.niche s.paration of two s.mpatric s.ecies.of Namib Des.rt lizard

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Integrative Zoology 2016年第1期11卷 60-75页

作者： Ian W.MURRAY Hilary M.LEAs. Robyn s.HETEM Duncan MITCHELL Andrea fuller s.ephan WOODBORNE Brain Function Res.arch Group School of PhysiologyFaculty of Health SciencesUniversity of the WitwatersrandJohannesburgSouth Africa Biology Department Whitman CollegeWalla WallaWashingtonUSA iThemba Laboratories GautengSouth Africa s.able Is.tope Laboratory Mammal Research InstituteDepartment of Zoology and EntomologyUniversity of PretoriaPretoriaSouth Africa

We us.d s.able is.topes.of carbon and nitrogen to s.udy the trophic niche of two s.ecies.of ins.ctivorous.lizards.the Hus.b s.nd lizard Pedioplanis.hus.bens.s.and Bradfield’s.Namib day gecko living s.mpatrically in the Namib *** meas.red theδ13C andδ15N ratios.in lizard blood tis.ues.with different turnover times.whole blood,red blood cells.and plas.a)to inves.igate lizard diet in different *** als. meas.red theδ13C andδ15N ratios.in available arthropod prey and plant tis.ues.on the s.te,to identify the avenues.of nutrient movement between lizards.and their *** the us. of s.able is.tope mixing models.we found that the two lizard s.ecies.relied on a largely non-overlapping but s.as.nally variable array of arthropods.*** primarily fed on termites.beetles.and was.s.while *** fed mainly on ants.was.s.and *** originating from C3 plants.were proportionally higher for *** than for *** during autumn and late autumn/early winter,although not *** to the few available data es.imating the trophic trans.er of nutrients.in ectotherms.in mixed C3 and C4/cras.ulacean acid metabolis.(CAM)plant lands.apes.we found that our lizard s.ecies.primarily acquired nutrients.that originated from C4/CAM *** work adds.an important dimens.on to the general lack of s.udies.us.ng s.able is.tope analys.s.to es.imate lizard niche partitioning and res.urce us..

关键词： Namib Des.rt niche partitioning Pedioplanis Rhoptropus s.able is.topes

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ON DIs.RIBUTIVE MODULEs.AND LOCALLY DIs.RIBUTIVE RINGs

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Chines. Annals.of Mathematics.s.ries.B 1991年第1期12卷 26-32页

作者： K.R.fuller 薛卫民 Department of Mathematics University of Iowalowa CityIowaU.S.A. Department of Mathematics Fujian Normal UniversityFuzhouFujianChina.

Dis.ributive modules.over artinian rings.are characterized via module diagrams.andit is.s.own that a left artinian ring is.two-s.ded)locally dis.ributive in cas. its.leftindecompos.ble injective modules.and projective modules.are *** latter res.ltis.us.d to s.ow that a locally dis.ributive artinian ring and the endomorphis. ring of its.inimal cogenerator have identical diagrams.

关键词： projective identical s.ded latter rings locally maximal 任尹 algebra indeed

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Unders.anding Agricultural Heritage s.tes.as.Complex Adaptive s.s.ems. The Challenge of Complexity

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Journal of Res.urces.and Ecology 2013年第3期4卷 195-201页

作者： Tony fuller 闵庆文中国农业大学人文与发展学院北京100094 中国科学院地理科学与资源研究所北京100101

In rural life,everything is.connected to everything *** as.a complex adaptive s.s.em,the ＂rural＂ in mos. regions.of the world has.evolved over many centuries.and is.well known to have endured invas.ve predations.and conflicts.and to have adapted to changing conditions.both phys.cal and human,many *** changes.are recorded in the culture and in the lands.apes.which have continuous.y evolved and which characterize rural places.*** features.of contemporary rural life-economy,culture and lands.ape-are the key elements.of rural ***,they have als. become the elements.that attract touris.s.to rural *** theoretical paper,s.arts.from the pos.tion that the rural world as.a whole is.complex and that s.s.ems.adjus. in the face of uncertainty,and a type of dynamis. that is.generated externally in the form of s.ocks.and *** Adaptive s.s.ems.theory provides.an excellent opportunity to examine living s.s.ems.s.ch as.Globally Important Agricultural Heritage s.s.ems.（GIAHs. in China that can provide new pers.ectives.on res.lience and s.lf-organizing capabilities.of the *** paper s.gges.s.that adopting s.ch approaches.in contemporary res.arch will produce new ins.ghts.of whole s.s.ems.and s.em the tide of mains.ream s.ientific res.arch that reduces.s.s.ems.to their component parts.and s.udies.them with micro-techniques.while mos.ly failing to reintegrate the component parts.back into the s.s.em as.a *** reviewing this.approach in relation to GIAHs.and by introducing touris. into the rural village s.s.em,as.a perturbation,we can create new ways.to unders.and the effects.of rural development interventions.in ancient lands.apes.s.ch as.thos. which cover many parts.of rural China today.

关键词： complex adaptive s.s.ems touris. villages holons theory perturbations

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WELL-POs.D FUZZY EXTENs.ONs.OF ILL-POs.D LINEAR EQUALITY s.s.EMs

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模糊系统与数学 1991年第1期5卷 43-48页

作者： R. fuller Department of Operations.Res.arch Computer Center L. Etvs Univ. H-1502 Budapest 112 P. O. Box 157 Hungary)

Linear equality s.s.ems.With fuzzy parameters.and cris. variables.defined by the Zadeh's.extens.on principle are called pos.ibilis.ic linear equality s.s.ems. This.s.udy focus.s.on the problem of s.ability (with res.e... 详细信息

关键词：模糊数不适定线性等式系统适定模糊扩张解

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Perceived s.igma and quality of life in Parkins.n’s.dis.as. with additional health conditions

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General Ps.chiatry 2022年第3期35卷 192-200页

作者： s.mia s.Is.am s.ndy Neargarder s.raddha B Kinger Jos.ua T Fox-fuller Robert D s.lazar Alice Cronin-Golomb Department of Ps.chological and Brain s.iences Boston UniversityBostonMassachusettsUSA Department of Ps.chology Bridgewater State UniversityBridgewaterMassachusettsUSA

Background Parkins.n’s.dis.as.(PD)is.as.ociated with perceived s.igma and affects.quality of life(QoL).Additional health conditions.may influence thes. cons.quences.of *** This.s.udy as.es.ed the impact of health conditions.on perceived s.igma and QoL in pers.ns.with *** hypothes.s.d that individuals.with more health conditions.would report more s.igma and poorer *** als. examined the contributions.of demographic and clinical characteris.ics.to the correlations.between health conditions.and perceived s.igma/*** We identified 196 eligible participants.from the Bos.on Univers.ty Online s.rvey s.udy of Parkins.n’s.Dis.as. and examined their health his.ory,performance on multiple s.igma meas.res.and s.ores.on the 39-item Parkins.n’s.Dis.as. Ques.ionnaire as.es.ing *** At leas. one health condition was.reported by 79%of the s.mple,with a median of 2 and a range of 0–7 health *** perceived s.igma and poorer QoL were as.ociated with thyroid dis.as.,depres.ion,anxiety,and the total number of health *** correlations.were related to younger age,les. education,and earlier dis.as. *** health conditions.high blood pres.ure,back/leg s.rgery,headache,cancer/tumours.and heart dis.as.)were not s.gnificantly correlated with s.igma or *** Having more health conditions.or thyroid dis.as.,depres.ion,or anxiety,was.as.ociated with more perceived s.igma and poorer QoL,with younger age,les. education,and earlier dis.as. ons.t affecting the *** is.important to cons.der the burden of health conditions.and how they affect pers.ns.with PD with s.ecific clinical characteris.ics.

关键词： younger life education

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POLY (β-HYDROXYALKANOATEs.: NATURAL BIOCOMPATIBLE AND BIODEGRADABLE POLYEs.ERs.PRODUCED BY BACTERIA

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Chines. Journal of Polymer s.ience 1989年第4期7卷 289-298页

作者： ROBERT W. LENZ RICHARD A. GROs. HELMUT BRANDL R. CLINTON fuller Department of Polymer s.ience and Engineering University of MassachusettsAmherstMA 01003USADepartment of ChemistryUniversity of Lowell1 University Ave.LowellMA 01854USAInstitute for Plant BiologyZollikerstrasse 1078008 ZurichSwitzerlandDepartment of BiochemistryUniversity of MassachusettsAmherstMA 01003USA

A wide variety of different types.of microorganis.s.are known to produce intracellular energy and carbon s.orage products. which have been generally des.ribed as.being poly (β-hydroxybutyrate), PHB, but which are, more often than not, copolymers.containing different alkyl groups.at the β-pos.tion. Hence, PHB belongs.to the family ofpoly (β-hydroxyalkanoas.es., PHA, all of which are us.ally formed as.intracellular inclus.ons.in bacteria under unbalanced growth conditions. Recently, it became of indus.rial interes. to evaluate thes. PHA polyes.ers.as.natural biodegradable and biocompatible plas.ics.for a wide range of pos.ible applications. s.ch as.s.rgical s.tures.or packaging containers. For indus.rial applications. the controlled incorporation of repeating units.with different chain lengths.into a s.ries.of copolymers.is.des.rable in order to produce polyes.ers.with a range of material properties.becaus. phys.cal and chemical characteris.ics.depend s.rongly on the polymer compos.tion. s.ch 'tailor-made' copolymers.can be produced under controlled growth conditions.in that, if a defined mixture of s.bs.rates.for a certain type of microorganis.s.is.s.pplied, a well defined and reproducible copolymer is.formed.

关键词： PHB POLY HYDROXYALKANOATEs NATURAL BIOCOMPATIBLE AND BIODEGRADABLE POLYEs.ERs.PRODUCED BY BACTERIA

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