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Shot lining of magnesium alloy with hard powders

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Transactions of Nonferrous Metals Society of China 2010年第B07期20卷 708-712页

作者： Y.HARAdA I.fukuda Graduate School of Engineering University of Hyogo Yatsushiro National College of Technology

To improve the surface properties,lining of magnesium alloys with hard powders by shot peening was carried out in order. The hard powders were tried to bond to the workpiece surface due to the collision of many *** order to fix the hard powders to the surface of the workpiece,the powders were set on an uneven *** easily facilitate fixing of powders,lining of the workpiece with the powder sandwiched between two aluminum foil sheets was also *** this experiment,a centrifugal shot peening machine with an electrical heater was *** workpieces were magnesium alloys AZ31B and AZ91d,and the hard powders were commercial cemented carbide,alumina,and *** joinability of hard powders near the lined surface was observed by a optical *** wear resistance was also evaluated by a wear *** hard powders were successfully bonded to the surface of workpieces by the shot lining *** results show that the present method is effective in wear resistance of the magnesium alloys.

关键词： shot peening surface treatment lining joining joinability magnesium alloy hardness wear resistance cemented carbide ceramic

Methods of induced pluripotent stem cells for clinical application

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World Journal of Stem Cells 2015年第1期7卷 116-125页

作者： Tomohisa Seki Keiichi fukuda department of Cardiology Keio University School of Medicine Tokyo 160-8582 Japan department of Emergency and Critical Care Medicine Keio University School of Medicine Tokyo 160-8582 Japan

Reprograming somatic cells using exogenetic gene expression represents a groundbreaking step in regenerative medicine. Induced pluripotent stem cells(i PSCs) are expected to yield novel therapies with the potential to solve many issues involving incurable diseases. In particular, applying i PSCs clinically holds the promise of addressing the problems of immune rejection and ethics that have hampered the clinical applications of embryonic stem cells. However, as i PSC research has progressed, new problems have emerged that need to be solved before the routine clinical application of i PSCs can become established. In this review, we discuss the current technologies and future problems of human i PSC generation methods for clinical use.

关键词： Induced pluripotent stem cells Cell reprogramming

A synchronous distributed cloud-based virtual reality meeting system for architectural and urban design

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Frontiers of Architectural Research 2014年第4期3卷 348-357页

作者： Lei Sun Tomohiro fukuda Bernd Resch School ol Engineering Osaka University Suito Osaka S 4521 Japan Institute of Geography University of Heidelberg Heidelberg D 69120 Germany Harvard University Cambridge MA USA

In the spatial design fields such as architectural design and urban design, a consensus-building process among a variety of stakeholders like project executors, architects, residents, users, and general citizens is required. New technological developments such as cloud computing and Virtual design Studios （VdS） enable the creation of virtual meeting systems. This paper proposes an approach towards a synchronous distributed design meeting system. In this paper, in addition to sharing a 3d virtual space for a synchronous distributed type design meeting, we developed a prototype system that enables participants to sketch or make annotations and have discussions as well as add viewpoints to them. We applied these functions to evaluate an architectural design and urban landscape examination. In conclusion, the proposed method was evaluated as being effective and feasible. Yet, it shows a few shortcomings including the fact that simultaneous operation is limited to one client, and more arbitrary shapes should be supported in future versions of the application.

关键词： Spatial design meeting distributed synchronization Cloud computing Annotation discussion board

Improvement of registration accuracy of a handheld augmented reality system for urban landscape simulation

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Frontiers of Architectural Research 2014年第4期3卷 386-397页

作者： Tomohiro fukuda Tian Zhang Nobuyoshi Yabuki Graduate School of Engineering Osaka University Suita Osaka 565-0871 Japan Nikken Space design Ltd. Bunkyo-ku Tokyo Japan

The need for visual landscape assessment in large-scale projects for the evaluation of the effects of a particular project on the surrounding landscape has grown in recent years. Augmented reality （AR） has been considered for use as a landscape simulation system in which a landscape assessment object created by 3d models is included in the present surroundings. With the use of this system, the time and the cost needed to perform a 3dCG modeling of present surroundings, which is a major issue in virtual reality, are drastically reduced. This research presents the development of a 3d maporiented handheld AR system that achieves geometric consistency using a 3d map to obtain position data instead of GPS, which has tow position information accuracy, particularly in urban areas. The new system also features a gyroscope sensor to obtain posture data and a video camera to capture live video of the present surroundings. All these components are mounted in a smartphone and can be used for urban landscape assessment. Registration accuracy is evaluated to simulate an urban landscape from a short- to a long-range scale. The latter involves a distance of approximately 2000 m. The developed AR system enables users to simulate a Landscape from multiple and longdistance viewpoints simultaneously and to walk around the viewpoint fields using only a smartphone. This result is the tolerance level of Landscape assessment. In conclusion, the proposed method is evaluated as feasible and effective.

关键词： Landscape simulation Augmented reality Handheld device Registration accuracy Assessment

High circulating tumor cell concentrations in a specific subtype of gastric cancer with diffuse bone metastasis at diagnosis

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World Journal of Gastroenterology 2016年第26期22卷 6083-6088页

作者： Kazuhiro Shimazu Koji fukuda Taichi Yoshida Masahiro Inoue Hiroyuki Shibata department of Clinical Oncology Graduate School of Medicine Akita University

AIM: To clarify the biological feature contributing to gastric cancer with diffuse bone metastases at ***: The participants visited the department of Clinical Oncology, Akita University Hospital, from January 2014 to August 2015. The selection criterion for gastric cancer with diffuse bone metastases at diagnosis includes over 29 hot spots of bone scintigraphy. Circulating tumor cell were collected from 20 m L of peripheral venous blood drawn using a Cell Search kit and a Cell Tracks Auto Prep system by SRL, a clinical laboratory. The endpoints of this study were correlations between circulating tumor cells(CTC) count and therapeutic outcomes. RESULTS: Among 39 patients with gastric cancer, 5 patients met the criterion. The incidence of this subtype was 12.8%. CTC counts ranged from 235 to 6440 cells/7.5 m L of peripheral blood(median of 1724). These values were much higher than common gastric cancers(2 cells). In chemo-sensitive cases, CTC counts decreased within 14 d(median) from 275, 235 and 1724 to 2, 7 and 66, respectively. On the other hand, CTC counts increased after treatment failure or insensitive case from 2, 7 and 6440 to 787, 513 and 7885, respectively. The correlation between CTC count and survival time showed a trend, but did not reach significance(Y = 234.6- 0.03 X, P = 0.085).CONCLUSION: High CTC count is a biological hallmark of this subtype, and can be used as a direct and definitive indicator of therapeutic outcome.

关键词： Bone metastasis Circulating tumor cell Gastric cancer Predictive biomarker Prognostic biomarker

Precise measurement of magnetic moment of short-lived β-emitting nuclei ^(12)B (I~π=1^+,T_(1/2)=20.18 ms)

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Science China(Physics,Mechanics & Astronomy) 2004年第5期47卷 531-539页

作者： M. Mihara M. fukuda K. Matsuta T. Minamisono Graduate School of Science Osaka University Toyonaka Osaka 560-0043 JapanGraduate School of Science Osaka University Toyonaka Osaka 560-0043 JapanGraduate School of Science Osaka University Toyonaka Osaka 560-0043 JapanGraduate School of Science Osaka University Toyonaka Osaka 560-0043 Japan

The spin polarized β-emitting nuclei12B (I π=1+,T 1/2=20.18 ms) were produced by the nuclear reaction11B(d, p)12B and by the selection technique of the incident deuteron energy and the12B recoil angle following the nuclear reaction. The nuclear magnetic moment of the short-lived nuclei12B was measured by β-NMR with the β-NMR and β-NQR setup established for the first time in China. The nuclear magnetic moment of12B was determined to be μ=0.99993±0.00048 nm org=0.99993±0.00048 after the precise correction of the Knight shift.

关键词： short-lived 12B (Iπ = 1+, T1/2 = 20.18 ms) nuclei, nuclear magnetic moment, Knight shift, β-NMR.

differences in spatial understanding between physical and virtual models

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Frontiers of Architectural Research 2014年第1期3卷 28-35页

作者： Lei Sun Tomohiro fukuda Toshiki Tokuhara Nobuyoshi Yabuki Graduate School of Engineering Osaka University Osaka 565-0871 Japan

In the digital age, physical models are still used as major tools in architectural and urban design processes. The reason why designers still use physical models remains unclear. In addition, physical and 3d virtual models have yet to be differentiated. The answers to these questions are too complex to account for in all aspects. Thus, this study only focuses on the differences in spatial understanding between physical and virtual models. In particular, it emphasizes on the perception of scale. For our experiment, respondents were shown a physical model and a virtual model consecutively. A questionnaire was then used to ask the respondents to evaluate these models objectively and to establish which model was more accurate in conveying object size. Compared with the virtual model, the physical model tended to enable cluicker and more accurate comdarisons of building heights.

关键词： Spatialunderstanding Scale perception Physical model Virtual model Virtual reality

EFFECTS OF SURFACE CONdITIONS ON TRANSIENT POOL BOILING CHF IN VARIOUS LIQUIdS WITH dIFFERENT MECHANISMS dEPENdING ON PRESSURE ANd SUBCOOLING

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EFFECTS OF SURFACE CONDITIONS ON TRANSIENT POOL BOILING CHF ...

Accurate modulation of photoprinting under stiffness imaging feedback for engineering ECMs with high-fidelity mechanical properties

第十三届国际核工程大会

作者： J.d.Park Katsuya fukuda Graduate School of Science and Technology Kobe University Graduate School of Science and Technology Kobe University

＜正＞ 1 INTROdUCTIONThe general understanding of the transient CHFs in a pool of water at various pressures due to exponentially increasing heat inputs is necessary as the database for the correct prediction of the design-based nuclear reactor accident due to a power burst. Recently the steady-state pool boiling CHF for a horizontal cylinder in water and wetting liquids such as liquid nitrogen, liquid helium etc. were measured for comparatively wide

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Microsystems & Nanoengineering 2022年第3期8卷 291-301页

作者： Xin Li Huaping Wang Xinyi dong Qing Shi Tao Sun Shingo Shimoda Qiang Huang Toshio fukuda Intelligent Robotics Institute School of Mechatronical EngineeringBeijing Institute of TechnologyBeijing 100081China The Key Laboratory of Biomimetic Robots and Systems(Beijing Institute of Technology) Ministry of EducationBeijing 100081China School of Medical Technology Beijing Institute of TechnologyBeijing 100081China Intelligent Behavior Control Collaboration Unit RIKEN Center of Brain Science463-0003 NagoyaJapan

Engineered extracellular matrices(ECMs)that replicate complex in-vivo features have shown great potential in tissue *** hydrogel microstructures have been widely used to replace these native ECMs for physiologically relevant ***,accurate reproduction of the 3d hierarchical and nonuniform mechanical stffness inside one integrated microstructure to mimic the complex mechanical properties of native ECMs presents a major ***,by using digital holographic microscopy(dHM)-based stffness imaging feedback,we propose a novel closed-loop control algorithm to achieve high-accuracy control of mechanical properties for hydrogel microstructures that recapitulate the physiological properties of native ECMs with high *** photoprinting,the photocuring area of the hydrogel is divided into microscale grid areas to locally control the photocuring *** the assistance of a motorized microfluidic channel,the curing thickness is controlled with layer-by-layer *** dHM-based stiffness imaging feedback allows accurate adjustment of the photocuring degree in every grid area to change the crosslinking network density of the hydrogel,thus enabling large-span and high-resolution modulation of mechanical ***,the gelatin methacrylate was used as a typical biomaterial to construct the highfidelity biomimetic *** Young's modulus could be flexibly modulated in the 10 kPa to 50 kPa ***,the modulus gradient was accurately controlled to within 2.9 *** engineering ECM with locally different mechanical properties,cell spreading along the stff areas was observed *** believe that this method can regenerate complex biomimetic ECMs that closely recapitulate in-vivo mechanical properties for further applications in tissue engineering and biomedical research.

关键词： microstructure ECM curing