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Spraying printing of liquid metal electronics on various clothes to compose wearable functional device

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Science China(Technological Sciences) 2017年第2期60卷 306-316页

作者： GUI han TAN SiCong WANG Qian YU Yang LIU fujun LIN Ju LIU Jing Department of Biomedical Engineering School of MedicineTsinghua UniversityBeijing 100084China Beijing Key Lab of Cryo Biomedical Engineering and Key Lab of Cryogenics Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190China

Liquid metal printing is emerging as an important tool for making wearable electronics. However, very limited academic efforts were made to fulfill such an increasing need. This paper is dedicated to present relatively complete theoretical and experimental characterizations for liquid metal spraying printing towards developing wearable electronic textile. The practical conditions of liquid metal droplets in the spraying printing process such as the jet velocity, the size distribution of droplets and their evenness degree, the morphology of droplets and their unrolling areas after impacting the substrate are quantified. The dominating factors, including the oxidation of liquid metal and the pressure force on cloth substrate during the impacting process, which ensure liquid metal firmly adhere to the cloth, are clarified. Further, various clothes are comparatively investigated to test their capabilities in printing liquid metal conductors, where the resistance difference can be over thousand-fold. In addition to interpreting the basic mechanisms and performances of the spraying printing, two programmable flexible circuits with specifically designed functions such as blinking LED lighting and wireless infrared temperature measurement via current manufacture technology were also demonstrated and evaluated for their washable ability. With the realization of wearable modules via liquid metal printing technology, it can be expected that flexible functional devices on cloth fabricated quickly and directly would witness more broad applications in the coming time.

关键词： liquid metal wearable electronics spraying printing electronic cloth health care

Highly polar CoP/Co_(2)P heterojunction composite as efficient cathode electrocatalyst for Li-air battery

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Chinese Chemical Letters 2024年第9期35卷 486-490页

作者： Miaomiao Li Mengwei Yuan Xingzi Zheng Kunyu han Genban Sun fujun Li Huifeng Li Beijing Key Laboratory of Energy Conversion and Storage Materials College of ChemistryBeijing Normal UniversityBeijing 100875China Key Laboratory of Advanced Energy Materials Chemistry(Ministry of Education) College of ChemistryNankai UniversityTianjin 300071China Center for Advanced Materials Research Beijing Normal UniversityZhuhai 519087China

In order to advance the commercialization of rechargeable Li-air batteries,it is of importance to explore cathode catalyst with efficient catalytic *** metal oxides have poor electrical conductivity,while cobalt phosphide has excellent electrical conductivity and large specific surface ***,its application in organic Li-air batteries has been much less studied,and the electrocatalytic activity desires to be further ***,CoP/Co_(2)P heterojunction composite with higher polarity was *** discharge product of high-polarity CoP/Co_(2)P had a new porous box-like morphology,which was easy to be decomposed and exposed more active *** highly polar CoP/Co_(2)P heterostructure composite had homogeneous pores,the synergistic effect existed between CoP and Co_(2)P,and the discharge product was porous box mixed with Li_(2)O_(2)and LiOH,which made CoP/Co_(2)P achieve high specific capacity of14632 m Ah/g and cycle stably 161 times when used as air electrode cathode *** work furnished a thought for the construction of cathode catalysts with efficient catalytic activity for Li-air batteries.

关键词： Li-air battery Cathode catalyst CoP/Co_(2)P Heterojunction structure High polarity

低频电磁场对C2C12成肌过程中相关基因表达的影响

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中华实验外科杂志 2017年第1期34卷 85-85页

作者：韩福军毕佳琦李卫曲志伟孟庆刚哈尔滨市第一医院骨外六科 150010 哈尔滨医科大学哈尔滨市第一医院 150010

肌萎缩普遍存在于临床患者中；尚无特效治疗方式；而脉冲电磁场的生物学效应已被证实；我们通过研究电磁场对成肌诱导因子（MyoD）与Pax7表达的影响来探索肌萎缩的诊疗。一、材料与方法1．自制脉冲电磁场等。2．细胞处理：常规C2C12细... 详细信息

肌萎缩普遍存在于临床患者中；尚无特效治疗方式；而脉冲电磁场的生物学效应已被证实；我们通过研究电磁场对成肌诱导因子（MyoD）与Pax7表达的影响来探索肌萎缩的诊疗。一、材料与方法1．自制脉冲电磁场等。2．细胞处理：常规C2C12细胞培养、传代、分组即对照组A（0 mT），实验组B（0．5mT），实验c组（1．0mT），实验D组（1．5mT），定期取样送检。

关键词： C2C12 低频电磁场肌萎缩相关基因表达脉冲电磁场细胞培养生物学效应实验组

不同强度磁场对成肌过程中Pax7与Myf5表达的影响

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中华实验外科杂志 2017年第7期34卷 1201-1201页

作者：韩福军毕佳琦李卫曲志伟孟庆刚哈尔滨市第一医院骨科 150010

肌萎缩患者普遍存在于临床中，尚无有效治疗方式；而电磁场的生物学效应已被证实。我们通过研究脉冲电磁场对成肌诱导因子Myf5与Pax7表达研究肌萎缩治疗。

关键词：脉冲电磁场肌萎缩强度治疗方式生物学效应诱导因子

Hf0.5Zr0.5O2 1T–1C FeRAM arrays with excellent endurance performance for embedded memory

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Science China(Information Sciences) 2023年第4期66卷 303-304页

作者： Wenwu XIAO Yue PENG Yan LIU Huifu DUAN fujun BAI Bing YU Qiwei REN Xiao YU Genquan han School of Microelectronics Xidian University Xi'an UniIC Semiconductors Research Center for Intelligent Chips Zhejiang Lab hangzhou Institute of Technology Xidian University

Since the initial report of HfO2-based ferroelectric films in 2011, great attention has been paid to ferroelectric field-effect transistors and ferroelectric random-access memories(FeRAMs)[1–3]. Up to now, many efforts have been devoted to realizing the industrialization of HfO2-based FE films. However, the limited fatigue performance has always been the main problem to be resolved.

关键词：

基于社区2型糖尿病患者的心脑血管事件5年风险预测模型

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山东大学学报（医学版） 2017年第6期55卷 108-113页

作者：张振堂杨洋韩福俊陈向华季晓康王永超王淑康孙苑潆李敏陈亚飞王丽薛付忠刘言训青岛市黄岛区疾病预防控制中心山东青岛266400 山东大学公共卫生学院生物统计系山东济南250012 山东大学齐鲁生物医学大数据研究中心山东济南250012 山东大学公共卫生学院信息处理实验室山东济南250012 康评健康医疗大数据科技有限公司山东济南250101 山东电力中心医院心内科山东济南250001

目的构建新诊断的2型糖尿病患者5年内首次发生心脑血管事件的预测模型。方法研究对象选自青岛市黄岛区疾病预防控制中心慢性病管理系统,选择未发生过心脑血管事件的2型糖尿病患者2 899例作为训练样本,建立Cox模型和评分模型,并对模型进... 详细信息

目的构建新诊断的2型糖尿病患者5年内首次发生心脑血管事件的预测模型。方法研究对象选自青岛市黄岛区疾病预防控制中心慢性病管理系统,选择未发生过心脑血管事件的2型糖尿病患者2 899例作为训练样本,建立Cox模型和评分模型,并对模型进行内部验证;用"山东多中心健康管理纵向观察队列"中的1 016例2型糖尿病患者作为验证样本,对模型进行外部验证。结果随访期间训练样本共发生228例心脑血管事件,发病密度为16.86‰。模型变量包括年龄、性别、收缩压、低密度脂蛋白、高密度脂蛋白和心脑血管病家族史。训练样本Cox模型ROC曲线下面积(AUC)为0.678(95%CI:0.660~0.695),评分模型AUC为0.663(95%CI:0.648~0.680);外部验证Cox模型AUC为0.640(95%CI:0.608~0.676),评分模型AUC为0.631(95%CI:0.600~0.661)。结论研究建立的2型糖尿病患者心脑血管事件5年预测模型可以为社区糖尿病患者管理初期提供参考。

关键词：糖尿病并发症心脑血管病预测模型社区管理

LRRC25 plays a key role in all-trans retinoic acid-induced granulocytic differentiation as a novel potential leukocyte differentiation antigen

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Protein & Cell 2018年第9期9卷 785-798页

作者： Weili Liu Ting Li Pingzhang Wang Wanchang Liu fujun Liu Xiaoning Mo Zhengyang Liu Quansheng Song Ping Lv Guorui Ruan Wenling han Department of Immunology School of Basic Medical Sciences Key Laboratory of Medical Immunology (Ministry of Health) Peking University Health Science Center Beijing 100191 China Peking University Center for Human Disease Genomics Beijing 100191 China Institute of Hematology Peking University People's Hospital Beijing 100044 China

Leukocyte differentiation antigens （LDAs） play important roles in the immune system, by serving as surface markers and participating in multiple biological activities, such as recognizing pathogens, mediating membrane signals, interacting with other cells or systems, and regulating cell differentiation and activation. Data mining is a powerful tool used to identify novel LDAs from whole genome. LRRC25 （leucine rich repeat-containing 25） was predicted to have a role in the function of myeloid cells by a large-scale ＂omics＂ data analysis. Further experimental validation showed that LRRC25 is highly expressed in primary myeloid cells, such as granulocytes and monocytes, and lowly/intermediately expressed in B cells, but not in T cells and almost all NK cells. It was down-regulated in multiple acute myeloid leukemia （AML） cell lines and bone marrow cells of AML patients and up-regulated after all-trans retinoic acid （ATRA）-mediated granulocytic differentiation in AML cell lines and acute promyelocytic leukemia （APL; AML-M3, FAB classification） cells. Localization analysis showed that LRRC25 is a type I transmembrane molecule. Although ectopic LRRC25 did not promote spontaneous differentiation of NB4 cells, knockdown of LRRC25 by siRNA or shRNA and knockout of LRRC25 by the CRISPR-Cas9 system attenuated ATRA-induced termi- nal granulocytic differentiation, and restoration of LRRC25 in knockout cells could rescue ATRA-induced granulocytic differentiation. Therefore, LRRC25, a potential leukocyte differentiation antigen, is a key regulator of ATRA-induced granulocytic differentiation.

关键词： LRRC25 differentiation antigen granulocytic differentiation ATRA AML

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甘肃陇南不同种类花椒籽的营养成分对比研究

中国饲料 2024年第14期 14-19页

作者：张莉古雪艳韩富军徐国伟张康王磊郭志廷李建喜 hanyurwumutima Egide 刘佳惠张洺溪陈海瑜张景艳王学智甘肃省动物疫病预防控制中心甘肃兰州730046 中国农业科学院兰州畜牧与兽药研究所甘肃兰州730050 甘肃省农业科学院林果花卉研究所甘肃兰州730070 中国农业科学院兰州兽医研究所甘肃兰州730030

文章旨在以甘肃省陇南市文县九月青花椒籽、红花椒籽、无刺嫁接红花椒籽、为研究对象,采用凯氏定氮法、色谱法等测定花椒籽中蛋白、挥发油等主要营养成分的含量,评价3个不同种类花椒籽的饲用价值。结果表明,经过品种改良后,无刺嫁接花... 详细信息

文章旨在以甘肃省陇南市文县九月青花椒籽、红花椒籽、无刺嫁接红花椒籽、为研究对象,采用凯氏定氮法、色谱法等测定花椒籽中蛋白、挥发油等主要营养成分的含量,评价3个不同种类花椒籽的饲用价值。结果表明,经过品种改良后,无刺嫁接花椒籽中的水分、总灰分和粗纤维含量下降,粗蛋白和粗脂肪含量增加;无刺嫁接红花椒籽中粗脂肪、粗蛋白和挥发油含量显著高于九月青花椒籽和红花椒籽(P<0.05)。无刺嫁接红花椒籽中α-亚油酸、棕榈酸、硬脂酸、顺油酸、顺亚油酸和十五烷酸中含量显著高于九月青花椒籽(P<0.05)。无刺嫁接红花椒籽中的天冬氨酸、谷氨酸、精氨酸、甘氨酸、亮氨酸、丙氨酸、丝氨酸、苯丙氨酸、苏氨酸、缬氨酸、异亮氨酸、脯氨酸、组氨酸含量和氨基酸总量均显著高于九月青花椒籽和红花椒籽中的氨基酸含量(P<0.05)。无刺嫁接红花椒籽所含必需氨基酸中异亮氨酸、赖氨酸、蛋氨酸、苏氨酸均低于FAO/WHO的推荐值,且只在无刺嫁接红花椒籽中检测出蛋氨酸,其中亮氨酸、苯丙氨酸+酪氨酸和缬氨酸均高于FAO/WHO的推荐值。综上所述,3个不同种类的花椒籽中各组成成分种类和含量有所不同,其中无刺嫁接花椒籽富含多种营养成分,具有良好的饲用开发价值。

关键词：花椒籽不同品种甘肃陇南营养价值

核桃大豆间作土壤微生物生物量碳氮、氮素营养与酶活性特征

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土壤 2024年第5期56卷 982-991页

作者：刘小勇任静张锐郭志刚彭海韩富军刘馨蔚徐小强甘肃省农业科学院林果花卉研究所兰州730070 塔里木大学园艺与林学学院新疆阿拉尔843300 天水师范学院生物工程与技术学院甘肃天水741000 甘肃省煤田地质局兰州730030 天水市果树研究所甘肃天水741002

为掌握旱作区核桃大豆间作下土壤质量变化,探明土壤矿质营养、微生物生物量碳氮和酶活性变化特征及其相关性,以元林核桃(Juglans regia cv. L.)为研究对象,测定分析了核桃硬核期、坚果成熟期和落叶期3个关键物候期核桃大豆间作、核桃单... 详细信息

为掌握旱作区核桃大豆间作下土壤质量变化,探明土壤矿质营养、微生物生物量碳氮和酶活性变化特征及其相关性,以元林核桃(Juglans regia cv. L.)为研究对象,测定分析了核桃硬核期、坚果成熟期和落叶期3个关键物候期核桃大豆间作、核桃单作两种栽培模式下土壤矿质营养、微生物生物量碳(MBC)、微生物生物量氮(MBN)以及酶活性特征。结果表明:(1)间作显著提高了核桃生育期土壤有机质(SOM)含量,降低了核桃生育前期(硬核期和坚果成熟期)0~60 cm土层土壤碱解氮(AN)、有效磷(AP)含量和表层(0~20 cm)土壤速效钾(AK)含量,降低了土壤AN和AP的深层积累,加速了作物对营养元素的吸收利用,提高了养分利用效率;(2)间作提高了核桃生育期深层(40~60 cm)土壤MBC含量和硬核期土壤MBN含量,增加了坚果成熟期和落叶期0~40 cm土层土壤MBN含量,维持了深层土壤MBC含量;(3)间作条件下,土壤β-葡糖苷酶(BG)、磷酸单酯酶(AKP)、α-纤维素酶(CBH)、N-乙酰葡糖胺糖苷酶(NAG)和亮氨酸氨基肽酶(LAP)活性均以坚果成熟期最高、硬核期最低,而硬核期5种酶活性均显著低于单作处理,坚果成熟期和落叶期均高于单作处理,表现出较大的波动性;(4)Pearson相关性分析表明,土壤MBC与全氮(TN)、AN和SOM极显著正相关(P<0.01),间作下土壤MBC、MBN与AKP均显著相关(P<0.05);土壤BG、AKP、CBH、NAG和LAP之间均极显著正相关(P<0.01)。综上可见,旱作区幼龄核桃园间作大豆,可以显著增加核桃生育期SOM、AN和AP含量,降低土壤AN和AP的深层积累,提高深层土壤MBC含量,增大坚果成熟期土壤酶活性,加速作物对营养元素的吸收利用。

关键词：核桃大豆间作土壤微生物生物量碳氮酶活性矿质营养旱作区