检索结果-南通市图书馆

Carbetocin for the prevention of postpartum hemorrhage:a systematic review and meta-analysis of randomized controlled trials

在线全文

学校读者我要写书评

暂无评论

Carbetocin for the prevention of postpartum hemorrhage:a sys...

A Cytokinin Oxidase Coordinates the Source and Sink Relationship by Regulating Leaf Senescence and Grain Number of Rice

2015年泛长三角围产医学学术年会暨浙江省围产医学学术年会

作者： Bohong Jin Yongming Du fubin Zhang Kemei Zhang Lulu wang Lining Cui Department of Obstetrics & Gynecology Ningbo First Hospital

Objective To compare the efficacy and safety profile of carbetocin with other uterotonic agents in preventing postpartum *** PubMed,Web of Science,Scopus and EBSCOhost were searched for relevant randomized controlled trials published until September *** Carbetocin was associated with a significantly reduced need for additional uterotonic agents(RR=0.68,95%CI:0.55-0.84,I2=4%)compared with oxytocin in women following caesarean ***,with re-

关键词： Carbetocin meta-analysis postpartum hemorrhage systematic review uterotonic agent

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

A Cytokinin Oxidase Coordinates the Source and Sink Relation...

Experimental study of double tearing mode on EAST tokamak

第三届全国植物开花·衰老与采后生物学大会

作者： Wei Zhang Kaixuan Peng fubin Cui Jiangzhe Zhao Yuyang wang Kewei Zhang Institute of Plant Genetics and Developmental Biology College of Chemistry and Life Sciences Zhejiang Normal University

Photosynthesis and grain number contribute to the source and sink which determine the crop yield. Premature leaf senescence significantly reduces the photosynthesis and severely decreases the crop yield. Cytokinins play important roles in leaf senescence and determine grain number. In this study, we characterized the important roles of a cytokinin oxidase CKXa in the chlorophyll accumulation, leaf senescence and grain number, which coordinately regulate the source and sink. OsCKXa was predominantly expressed in the leaves and panicles under normal condition, strongly induced by abscisic acid（ABA） and leaf senescence. Further investigation revealed the recombinant protein OsCKXa catalyzes the degradation of various cytokinins and shows substrate specificity towards cZ and tZ in vitro. Consistently, the cytokinin levels in the flag leaves of osckxa mutants were significantly increased compared to that of wild type at same stage. On the contrary, ABA level was reduced and the expression level of ABA biosynthesis genes were reduced and degradation genes were upregulated in osckxa mutants compared with wild type, which suggests that OsCKXa serves as an antagonist’s point between cytokinins and ABA in leaf senescence. Additionally, osckxa mutants exhibited a significant improvement of grain number by the increase of the branch number and tiller number which formed a larger sink. The coordinately regulation of the source of photosynthesis and the sink of grain number contribute to the 10.62～15.94% increase in grain yield of three independent lines. Our findings reveal that OsCKXa is an important gene involved in modulating the cytokinin level to coordinate source and sink relationship which determine grain yield.

关键词： Cytokinin oxidase Source Sink Leaf senescence Grain number Rice

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Plasma Science and Technology 2020年第2期22卷 47-53页

作者： Mingfu WU Zixi LIU Tao ZHANG fubin ZHONG Gongshun LI Haoming XIANG Kangning GENG Kaixuan YE Jia HUANG Fei WEN Yumin wang Xiang HAN Shoubiao ZHANG Haiqing LIU Guoqiang LI Ge ZHUANG Xiang GAO University of Science and Technology of China Hefei 230026People's Republic of China Institute of Plasma Physics Chinese Academy of SciencesHefei 230031People's Republic of China Advanced Energy Research Center Shenzhen UniversityShenzhen 518060People’s Republic of China Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Optoelectronic EngineeringShenzhen UniversityShenzhen 518060People's Republic of China

The double tearing mode(DTM)in a high βN(βN>1.5)discharge with internal transport barrier on EAST was investigated.A 15 kHz tearing mode(TM)(m≥3,n=3)appears at outer q=2 surface at first,which is stable in the highβN *** a 2 kHz TM(m=2,n=1)occurs at inner q=2 *** after,high βN collapsed with the crash of ELM,and DTM formed during the collapse of β*** positions of the two islands of the DTM are consistent with the q=2 *** temperature fluctuations are the strongest between the two magnetic islands.A statistical analysis of high βN discharges operating with the reversed magnetic shear configuration in the EAST 2015-2018 campaign revealed the existence of the DTM in many *** the DTM phase,all βN are reduced by 10%-30% within 0.1 ***,there are two different βN behaviors thereafter-with and without βN *** the physical mechanism of βN recovery during the DTM phase will benefit steady-state operation with reversed shear configurations in the future.

关键词： highβN βN collapse EAST double tearing mode

孕期维生素D缺乏或不足与自发性流产相关性的Meta分析

在线全文

学校读者我要写书评

暂无评论

中华临床营养杂志 2022年第1期30卷 27-36页

作者：王煚楠邱服斌山西医科大学公共卫生学院营养与食品卫生学教研室太原030001

目的系统评价孕期维生素D缺乏或不足与自发性流产结局的相关性。方法计算机检索PubMed、Web of Science、Ebsco、Cochrane、Embase、中国知网(CNKI)、万方数据库、中国生物医学文献服务系统等数据库,收集研究孕期维生素D缺乏或不足和自... 详细信息

目的系统评价孕期维生素D缺乏或不足与自发性流产结局的相关性。方法计算机检索PubMed、Web of Science、Ebsco、Cochrane、Embase、中国知网(CNKI)、万方数据库、中国生物医学文献服务系统等数据库,收集研究孕期维生素D缺乏或不足和自发性流产结局相关性的队列研究和病例对照研究,检索时限均为建库至2021年12月。由2名研究者独立筛选文献,提取资料并评价纳入研究的偏倚风险后,采用RevMan5.4.1软件和Stata15.1软件进行Meta分析。结果最终纳入12篇队列研究和5篇病例对照研究。共纳入孕妇19308例,其中流产者1405例;8篇中文文献和9篇英文文献;其中10篇来自中国,来自伊朗、埃及、瑞典、美国、丹麦、土耳其、澳大利亚各1篇。各文献中维生素D缺乏标准和流产的诊断标准基本一致。Meta分析结果显示,孕期维生素D缺乏或不足会增加流产的风险。对妊娠早期流产女性进行亚组分析,结果与总体结果一致,Meta分析未见明显发表偏倚。结论维生素D缺乏或不足与自发性流产的发生有关,并能增加早期自然流产的发生风险。

关键词：维生素D 妊娠期流产 Meta分析

激光雷达/MEMS IMU/里程计紧组合导航算法

在线全文

学校读者我要写书评

暂无评论

仪器仪表学报 2022年第7期43卷 139-148页

作者：张福斌王凯廖伟飞孙成浩西北工业大学航海学院西安710000 中国飞行试验研究院西安710000

为提高机器人在未知复杂环境中导航系统的鲁棒性与稳定性,提出了一种激光雷达/MEMS IMU/里程计紧组合导航算法。首先通过MEMS IMU/里程计的预积分,对激光雷达运动产生的畸变点云进行矫正,提高两帧点云之间的特征匹配效率;然后根据时间... 详细信息

为提高机器人在未知复杂环境中导航系统的鲁棒性与稳定性,提出了一种激光雷达/MEMS IMU/里程计紧组合导航算法。首先通过MEMS IMU/里程计的预积分,对激光雷达运动产生的畸变点云进行矫正,提高两帧点云之间的特征匹配效率;然后根据时间戳对预积分的机器人位姿进行线性插值,得到两帧点云之间粗略的位姿变化量,以此粗略的位姿变化量作为优化算法迭代初值,减少优化算法的迭代次数;其次在后端优化中加入MEMS IMU/里程计的运动约束,利用多传感器联合优化来提高机器人的定位精度;最后利用数据集进行仿真实验、利用四轮小车开展了室内与室外开闭环实验,实验表明,本算法室外开环定位误差均值比传统算法ALOAM、LEGO-LOAM分别减小51.01%和24.75%,并且其在拐弯等运动剧烈时能够保持较高精度。

关键词：激光SLAM 紧组合多传感器点云畸变矫正

在线全文

学校读者我要写书评

暂无评论

人工关节置换治疗高龄股骨转子间粉碎性骨折

重庆医学 2013年第20期42卷 2356-2358页

作者：王霁隆晓涛杨阜滨重庆市中山医院骨科 400013

目的探讨人工关节置换治疗高龄股骨转子间粉碎性骨折的疗效。方法回顾性分析2007～2011年该院关节外科收治的187例经人工关节置换治疗的高龄股骨转子间粉碎性骨折患者资料,术后根据Harris评分评价患髋关节功能。结果围术期患者死亡1例,... 详细信息

目的探讨人工关节置换治疗高龄股骨转子间粉碎性骨折的疗效。方法回顾性分析2007～2011年该院关节外科收治的187例经人工关节置换治疗的高龄股骨转子间粉碎性骨折患者资料,术后根据Harris评分评价患髋关节功能。结果围术期患者死亡1例,术后186例获随访。Harris评分为45～96分,平均81.5分。其中优51例,良98例,优良率80.1%。165例患者在术后3个月的行走能力和生活自理能力均基本恢复至伤前水平。结论关节置换作为股骨转子间粉碎性骨折治疗方法的一种有效补充,能有效地提高高龄患者的生命质量、降低并发症发生率和病死率。

关键词：股骨转子间骨折关节置换高龄

Sin1/mTORC2 regulate B cell growth and metabolism by activating mTORC1 and Myc

在线全文

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2019年第9期16卷 757-769页

作者： Man Li Adam S.Lazorchak Xinxing Ouyang Huihui Zhang Hongzhi Liu Omotooke A.Arojo Lichong Yan Jingsi Jin Yuheng Han Guojun Qu Yuhong Fu Xiaocao Xu Xiaobo Liu Wenqian Zhang Zhengfeng Yang Chuan Ruan Qijun wang Dou Liu Chuanxin Huang Lu Lu Shibo Jiang fubin Li Bing Su Shanghai Institute of Immunology Department of Immunology and MicrobiologyKey Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of EducationShanghai Jiao Tong University School of MedicineShanghai 200025China Department of Immunobiology and the Vascular Biology and Therapeutics Program Yale University School of Medicine333 Cedar StreetNew HavenConnecticut 06520USA Present address:EMD Serono Research&Development Institute Inc.45 Middlesex TpkeBillericaMA 01821–3936USA Hongqiao International Institute of Medicine Shanghai Tongren Hospital and Faculty of Basic MedicineShanghai Jiao Tong University School of MedicineShanghai 200025China Shanghai Public Health Clinical Center and School of Basic Medical Sciences Key Laboratory of Medical Molecular Virology of MOE/MOHFudan UniversityShanghaiChina

Proper control of B cell growth and metabolism is crucial for B-cell-mediated immunity,but the underlying molecular mechanisms remain incompletely *** this study,Sin1,a key component of mTOR complex 2(mTORC2),specifically regulates B cell growth and *** ablation of Sin1 in B cells reduces the cell size at either the transitional stage or upon antigen stimulation and severely impairs ***1 deficiency also severely impairs B-cell proliferation,antibody responses,and anti-viral *** the molecular level,Sin1 controls the expression and stability of the c-Myc protein and maintains the activity of mTORC1 through the Akt-dependent inactivation of GSK3 and TSC1/2,***,our study reveals a novel and specific role for Sin1 in coordinating the activation of mTORC2 and mTORC1 to control B cell growth and metabolism.

关键词： metabolism immunity stimulation

Experimental investigation on divertor tungsten sputtering with neon seeding in ELMy H-mode plasma in EAST tokamak

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics B 2022年第6期31卷 512-517页

作者： Dawei Ye Fang Ding Kedong Li Zhenhua Hu Ling Zhang Xiahua Chen Qing Zhang Pingan Zhao Tao He Lingyi Meng Kaixuan Ye fubin Zhong Yanmin Duan Rui Ding Liang wang Guosheng Xu Guangnan Luo EAST team Institute of Plasma Physics HFIPSChinese Academy of Sciences(CAS)Hefei 230031China University of Science and Technology of China Hefei 230026China

Neon(Ne)seeding is used to cool the edge plasma by radiation to protect the divertor tungsten(W)target in the Experimental Advanced Superconducting Tokamak(EAST).The W sputtering in the outer divertor target with Ne seeding is assessed by the divertor visible spectroscopy *** is observed that the W sputtering flux initially increases with Ne concentration in the divertor despite the decreasing plasma *** reaching a maximum around 25 eV,the W sputtering rate starts to decrease,presenting a suppression *** effect on the divertor W sputtering flux and yield due to the competition between the increase of the Ne concentration and the decrease of the plasma temperature is *** results show that enough Ne seeding is essential to effectively reduce the electron temperature and thus to suppress W ***,ELM suppression is observed when Ne and W impurities enter the core plasma,which could be correlated to the enhanced turbulence transport in the pedestal.

关键词： neon seeding tungsten sputtering ELM suppression EAST tokamak

A T-box Binding Site Mediates the Dorsal Activation of myf-5 in Xenopus Gastrula Embryos

在线全文

学校读者我要写书评

暂无评论

A T-box Binding Site Mediates the Dorsal Activation of myf-5...