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A new horizon for neuroscience:terahertz biotechnology in brain research

Neural Regeneration Research 2025年第2期20卷 309-325页

作者： Zhengping Pu Yu Wu Zhongjie Zhu Hongwei zhao Donghong Cui Shanghai Key Laboratory of Psychotic Disorders Shanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghaiChina Department of Psychiatry Kangci Hospital of JiaxingTongxiangZhejiang ProvinceChina Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghaiChina Key Laboratory of Interfacial Physics and Technology Shanghai Institute of Applied PhysicsChinese Academy of ScienceShanghaiChina National Facility for Protein Science in Shanghai Shanghai Advanced Research InstituteChinese Academy of SciencesShanghaiChina

Terahertz biotechnology has been increasingly applied in various biomedical fields and has especially shown great potential for application in brain *** this article,we review the development of terahertz biotechnology and its applications in the field of *** evidence indicates promising prospects for the use of terahertz spectroscopy and terahertz imaging techniques in the diagnosis of amyloid disease,cerebrovascular disease,glioma,psychiatric disease,traumatic brain injury,and myelin *** vitro and animal experiments have also demonstrated the potential therapeutic value of terahertz technology in some neuropsychiatric *** the precise underlying mechanism of the interactions between terahertz electromagnetic waves and the biosystem is not yet fully understood,the research progress in this field shows great potential for biomedical noninvasive diagnostic and therapeutic ***,the biosafety of terahertz radiation requires further exploration regarding its two-sided efficacy in practical *** review demonstrates that terahertz biotechnology has the potential to be a promising method in the field of neuropsychiatry based on its unique advantages.

关键词： biological effect brain neuron neuropsychiatry neuroscience non-thermal effect terahertz imaging terahertz radiation terahertz spectroscopy terahertz technology

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Lipomatous ependymoma with ZFTA:RELA fusion-positive:A case report

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World Journal of Clinical Cases 2025年第1期13卷 48-55页

作者： Xiao-Yu zhao Juan-Han Yu Yi-Hua Wang Yi-Xin Liu Lu Xu Lin fu Ning Yi China Medical University The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Department of Pathology The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Anshan Cancer Hospital Anshan 114000Liaoning ProvinceChina

BACKGROUND Ependymoma with lipomatous differentiation is a rare type of *** ZFTA fusion-positive supratentorial ependymoma is a novel tumor type in the 2021 World Health Organization classification of central nervous system *** fusion-positive lipomatous ependymoma has not been reported to *** SUMMARY We reported a case of a 15-year-old Chinese male who had a sudden convulsion lasting approximately six *** resonance imaging showed a round cystic shadow of approximately 1.9 cm×1.5 cm×1.9 cm under the right parieto-occipital *** examination showed characteristic perivascular pseudorosettes and adipose differentiation in the ***-chemical staining showed that the tumor cells were negative for cytokeratin,NeuN,Syn and p53,but positive for GFAP,vimentin and S-100 ***-ficant punctate intracytoplasmic EMA immunoreactivity was *** level of Ki-67 was about 5%.Genetic analysis revealed ZFTA:RELA fusion.A cranio-tomy with total excision of the tumor was *** follow-up time was 36 months,no evidence of disease recurrence was found in magnetic resonance *** Based on these findings,the patient was diagnosed as a ependymoma with ZFTA fusion and lipomatous *** case report provides information on the microscopic morphological features of ependymoma with ZFTA fusion and lipomatous differentiation,which can help pathologists to make a definitive diagnosis of this tumor.

关键词： Ependymoma Lipomatous Molecular classification Supratentorial ZFTA:RELA fusion Case report

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Preparation of FeCoNi medium entropy alloy from Fe^(3+)-Co^(2+)-Ni^(2+)solution system

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 92-101页

作者： Zongyou Cheng Qing zhao Mengjie Tao Jijun Du Xingxi Huang Chengjun Liu Key Laboratory for Ecological Metallurgy of Multimetallic Mineral(Ministry of Education) Northeastern UniversityShenyang 110819China School of Metallurgy Northeastern UniversityShenyang 110819China Engineering Research Center of Frontier Technologies for Low-carbon Steelmaking(Ministry of Education) Shenyang 110819China

In recent years,medium entropy alloys have become a research hotspot due to their excellent physical and chemical *** controlling reasonable elemental composition and processing parameters,the medium entropy alloys can exhibit similar properties to high entropy alloys and have lower *** this paper,a FeCoNi medium entropy alloy precursor was prepared via sol-gel and coprecipitation methods,respectively,and FeCoNi medium entropy alloys were prepared by carbothermal and hydrogen *** phases and magnetic properties of FeCoNi medium entropy alloy were *** showed that FeCoNi medium entropy alloy was produced by carbothermal and hydrogen reduction at 1500℃.Some carbon was detected in the FeCoNi medium entropy alloy prepared by carbothermal *** alloy prepared by hydrogen reduction was uniform and showed a relatively high ***,the hydrogen reduction product exhibited better saturation magnetization and lower coercivity.

关键词： medium entropy alloy sol-gel co-precipitation carbothermal hydrogen reduction

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湖北省古银杏资源调查与生长特性分析

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林业科技开发 2013年第1期27卷 50-54页

作者：付兆军邢世岩刘晓静刘莉娟任娟霞山东农业大学林学院山东泰安271018

以湖北省银杏古树为对象,通过资料收集和实地调查,结果显示:湖北省有银杏古树11 431株,分布在15个市(区),57个县(市、区)和123个乡(镇)。346株有生长指标,雌株占91.52%。树高最大为50.0 m,最小为6.0m;树龄最长为3 000 a;胸径最大为5.25... 详细信息

以湖北省银杏古树为对象,通过资料收集和实地调查,结果显示:湖北省有银杏古树11 431株,分布在15个市(区),57个县(市、区)和123个乡(镇)。346株有生长指标,雌株占91.52%。树高最大为50.0 m,最小为6.0m;树龄最长为3 000 a;胸径最大为5.25 m(基径),最小仅为0.35 m;平均冠幅最大为37.0 m,最小为4.5 m。垂乳银杏有19株,单株垂乳个数最多为84个,垂乳最长达80 cm;复干银杏有31株,单株复干数最多为40株,复干胸径最大为1.78 m。

关键词：湖北省古银杏资源生长特性

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飞行人员良性阵发性位置性眩晕的特点及航空医学鉴定

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解放军医学院学报 2013年第9期34卷 907-909,927页

作者：熊巍徐先荣郑军付兆君刘红巾空军总医院全军临床航空医学中心北京100142

摘要：目的分析飞行人员良性阵发性位置性眩晕（benignparoxysmalpositionalvertigo，BPPV）的临床特点，总结其航空医学鉴定原则。方法收集我院2000—2012年因BPPV住院的7例飞行人员临床资料，分析其临床特点、诊疗经过及航空医学鉴定... 详细信息

摘要：目的分析飞行人员良性阵发性位置性眩晕（benignparoxysmalpositionalvertigo，BPPV）的临床特点，总结其航空医学鉴定原则。方法收集我院2000—2012年因BPPV住院的7例飞行人员临床资料，分析其临床特点、诊疗经过及航空医学鉴定情况。结果7例均为原发性BPPV，其中后半规管BPPV5例，外半规管BPPV2例，病程最短者1周，最长者反复发作1年以上。均为在地面发作，没有飞行中发病情况。7例变位试验均为阳性，听力检查均正常。前庭双温试验6例正常，1例提示右侧半规管功能下降。3例在发病后2周内自愈，4例经过耳石复位治疗。短期（1周）疗效评价为：痊愈5例，有效1例，无效1例。长期（3个月）疗效评价为：痊愈6例，有效1例。所有患者均在治疗后给予3。6个月的地面观察，5例飞行合格，1例因心理原因停飞，1例因长期前庭功能异常停飞。结论因空中失能的风险及复发风险均较小，BPPV是周围性眩晕中可以完全康复并有望恢复飞行的疾病，但恢复飞行之前必须进行全面的前庭评价，根据病情特点、前庭功能恢复情况并结合飞行机种、飞行职务等进行医学鉴定。恢复飞行后需密切复查，了解疾病动态发展情况。

关键词：航空医学眩晕良性阵发性位置性眩晕飞行人员合格鉴定

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Relative Left Derived functors of Tensor Product functors

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Acta Mathematica Sinica,English Series 2016年第7期32卷 753-764页

作者： jun fu WANG zhao Yong HUANG School of Mathematical Sciences and Chemical Engineering Changzhou Institute of Technology Department of Mathematics Nanjing University

We introduce and study the relative lett derive functor Torn（￡,￡1） category, which unifies several related left derived functors. Then we give some criteria for computing the -resolution dimensions of modules in terms of the properties of Torn（￡,￡1） . We also construct a complete and hereditary cotorsion pair relative to balanced pairs. Some known results are obtained as corollaries.

关键词： Tensor product functors relative left derived functors balanced pairs cotorsion pairs,(co)resolution dimension

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Wave effect of gravitational waves intersected with a microlens field Ⅱ:An adaptive hierarchical tree algorithm and population study

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 241-254页

作者： Xikai Shan Guoliang Li Xuechun Chen Wen zhao Bin Hu Shude Mao Department of Astronomy Tsinghua University Purple Mountain Observatory Chinese Academy of Sciences Institute for Frontier in Astronomy and Astrophysics Beijing Normal University School of Physics and Astronomy Beijing Normal University School of Astronomy and Space Science University of Science and Technology of China CAS Key Laboratory for Researches in Galaxies and Cosmology Department of Astronomy University of Science and Technology of ChinaChinese Academy of Sciences

The gravitational lensing wave effect generated by a microlensing field embedded in a lens galaxy is an inevitable phenomenon in strong lensed gravitational waves （SLGWs）.This effect presents both challenges and opportunities for the detection and application of ***,investigating this wave effect requires computing a complete diffraction integral over each microlens in the *** is extremely time-consuming due to the large number of microlenses （10～3-10～6）.Therefore,simply adding all the microlenses is ***,the complexity of the time delay surface makes the lens plane resolution a crucial factor in controlling numerical *** this paper,we propose a trapezoid approximation-based adaptive hierarchical tree algorithm to meet the challenges of calculation speed and *** find that this algorithm accelerates the calculation by four orders of magnitude compared to the simple adding method and is one order of magnitude faster than the fixed hierarchical tree algorithm proposed for electromagnetic *** importantly,our algorithm ensures controllable numerical errors,increasing confidence in the *** with our previous work （***.66,239511,2023）,this paper addresses all numerical issues,including integral convergence,precision,and computational time1).Finally,we conducted a population study on the microlensing wave effect of SLGWs using this algorithm and found that the microlensing wave effect cannot be ignored,especially for Type II SLGWs （from saddle position of the time delay surface） due to their intrinsic geometric structures and their typical intersection with a denser microlensing ***,more than 33%（11%） of SLGWs have a mismatch larger than 1%（3%） compared to the unlensed ***,we found that the mismatch between signal pairs in a doubly imaged GW is generally larger than 10-3,and 61%（25%） of signal pairs have a mismatch larger than 1%（3%）.Therefo

关键词： gravitational lensing diffractional integral algorithm gravitational wave

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Multi-view ladar data registration in obscure environment

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Journal of Systems Engineering and Electronics 2013年第4期24卷 606-616页

作者： Mingbo zhao jun He Wei Qiu Qiang fu Science and Technology Automatic Target Recognition Laboratory National University of Defense Technology Unit 93246 of the PLA

Multi-view laser radar （ladar） data registration in obscure environments is an important research field of obscured target detection from air to ground. There are few overlap regions of the observational data in different views because of the occluder, so the multi-view data registration is rather difficult. Through indepth analyses of the typical methods and problems, it is obtained that the sequence registration is more appropriate, but needs to improve the registration accuracy. On this basis, a multi-view data registration algorithm based on aggregating the adjacent frames, which are already registered, is proposed. It increases the overlap region between the pending registration frames by aggregation and further improves the registration accuracy. The experiment results show that the proposed algorithm can effectively register the multi-view ladar data in the obscure environment, and it also has a greater robustness and a higher registration accuracy compared with the sequence registration under the condition of equivalent operating efficiency.

关键词： laser radar (ladar) multi-view data registration iterative closest point obscured target point cloud data.

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Range anomaly suppression based on neighborhood pixels detection in ladar range images

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Journal of Systems Engineering and Electronics 2013年第1期24卷 68-75页

作者： Mingbo zhao jun He Zaiqi Lu Qiang fu Automatic Target Recognition Key Laboratory School of Electronic Science and EngineeringNational University of Defense Technology No.93246 Troop of the PLA

Research on the range anomaly suppression algorithm in laser radar （ladar） range images is significant in the application and development of ladar. But most of existing algorithms cannot protect the edge and linear target well while suppressing the range anomaly. Aiming at this problem, the differences among the edge, linear target, and range anomaly are analyzed and a novel algo- rithm based on neighborhood pixels detection is proposed. Firstly, the range differences between current pixel and its neighborhood pixels are calculated. Then, the number of neighborhood pixels is detected by the range difference threshold. Finally, whether the current pixel is a range anomaly is distinguished by the neighbor- hood pixel number threshold. Experimental results show that the new algorithm not only has a better range anomaly suppression performance and higher efficiency, but also protects the edge and linear target preferably compared with other algorithms.

关键词： image processing range anomaly suppression neigh-borhood p xe s detection linear target laser radar (ladar).

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Rise of β-furanosyl ribonucleosides as the extant RNA component facilitated by simple divalent transition-metal minerals

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Science China Chemistry 2025年

作者： Qianqian Chen Haoxing Xu Bingyue zhao Yeersen Patehebieke Zerun zhao Xiao Wang School of Chemistry and Chemical Engineering Nanjing University Frontiers Science Center for Critical Earth Material Cycling Nanjing University

The selective nucleoside synthesis through direct condensation between nucleobase and unactivated sugar in aqueous media has long been a formidable obstacle for the early chemical transformations hypothesized to construct the RNAWorld, due to product complexity and the low selectivity of the desired isomer. The preference of β-furanoside, the extant RNA component, has never been documented. Here we report an aqueous ribosylation mediated by divalent transition-metal ions, which unprecedentedly enhances the selectivity of furanosyl ribonucleosides as opposed to the traditionally predominating pyranosyl ones, with the furanoside/pyranoside ratio reaching up to 9/1. furthermore, β-furanoside stands out for the first time as the most prevalent isomer in the presence of zinc and ammonium salts. The mechanism of this selectivity is elucidated with density functional theory calculations. The selectivity for β-furanoside can be further elevated via the adsorption on a zinc mineral. These findings exhibit as the first example that the selection of nucleosides with the desired, canonical configuration might be completed in the early stage of the RNA-forming process as opposed to later evolution, promoted by simple and widespread transition-metal minerals. The study may also find its value in synthetic chemistry as a guideline for developing a sustainable and selective glycosylation process.

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