检索结果-南通市图书馆

Mode coupling with Fabry-Perot modes in photonic crystal slabs

在线全文

学校读者我要写书评

暂无评论

Chinese Physics B 2024年第8期33卷 90-94页

作者：秦恳胡鹏刘杰向红韩德专 Department of Physics and Chongqing Key Laboratory for Strongly Coupled Physics Chongqing UniversityChongqing 401331China School of Science Chongqing Key Laboratory of New Energy Storage Materials and DevicesChongqing University of TechnologyChongqing 400054China

Fabry–Perot(FP)modes are a class of fundamental resonances in photonic crystal(PhC)*** to their low quality factors,FP modes are frequently considered as background fields with their resonance nature being ***,FP modes can play important roles in some phenomena,as exemplified by their coupling with guided resonance(GR)modes to achieve bound states in the continuum(BIC).Here,we further demonstrate the genuine resonance mode capability of FP modes PhC ***,we utilize temporal coupled-mode theory to obtain the transmittance of a PhC slab based on the FP ***,we construct exceptional points(EPs)in both momentum and parameter spaces through the coupling of FP and GR ***,we identify a Fermi arc connecting two EPs and discuss the far-field polarization *** work elucidates that the widespread FPs in PhC slabs can serve as genuine resonant modes,facilitating the realization of desired functionalities through mode coupling.

关键词： Fabry–Perot mode photonic crystal slab mode coupling exceptional point

Endoplasmic reticulum-targeted delivery of celastrol and PD-L1 siRNA for reinforcing immunogenic cell death and potentiating cancer immunotherapy

在线全文

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica B 2024年第8期14卷 3643-3660页

作者： Jie Wang Zilong Zhang Yan Zhuo zhuan Zhang Rongrong Chen Li Liang Xiaohe Jiang Di Nie Chang Liu Zhiwen Zou Xiang Li Jiaxin Li Bingqi Wang Rui Wang Yong Gan Miaorong Yu School of Pharmacy Shanghai University of Traditional Chinese MedicineShanghai 201203China State Key Laboratory of Drug Research Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Jiangxi Medical College Nanchang UniversityNanchang 330006China School of Pharmacy Nanjing University of Chinese MedicineNanjing 210023China University of Chinese Academy of Sciences Beijing 100049China NMPA Key Laboratory for Quality Research and Evaluation of Pharmaceutical Excipients National Institutes for Food and Drug ControlBeijing 100050China

The prospect of employing chemoimmunotherapy targeted towards the endoplasmic reticulum(ER)presents an opportunity to amplify the synergistic effects of chemotherapy and *** this study,we initially validated celastrol(CEL)as an inducer of immunogenic cell death(ICD)by promoting ER stress and autophagy in colorectal cancer(CRC)***,an ER-targeted strategy was posited,involving the codelivery of CEL with PD-L1 small interfering RNAs(siRNA)using KDEL peptide-modified exosomes derived from milk(KME),to enhance chemoimmunotherapy *** findings demonstrate the efficient transportation of KME to the ER via the Golgi-to-ER *** to their non-targeting counterparts,KME exhibited a significant augmentation of the CEL-induced ICD ***,it facilitated the release of danger signaling molecules(DAMPs),thereby stimulating the antigen-presenting function of dendritic cells and promoting the infiltration of T cells into the ***,the ER-targeted delivery of PD-L1 siRNA resulted in the downregulation of both intracellular and membrane PD-L1 protein expression,consequently fostering the proliferation and activity of CD8^(+)T ***,the ER-targeted formulation exhibited enhanced anti-tumor efficacy and provoked anti-tumor immune responses against orthotopic colorectal tumors in ***,a robust ER-targeted delivery strategy provides an encouraging approach for achieving potent cancer chemoimmunotherapy.

关键词： Chemoimmunotherapy Targeted drug delivery Endoplasmic reticulum Endoplasmic reticulum stress Immunogenic cell death siRNA Chemoimmunotherapy Targeted drug delivery Endoplasmic reticulum Endoplasmic reticulum stress Immunogenic cell death siRNA

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

基于系统动力学的交通领域氢能需求预测

电力自动化设备 2024年第4期44卷 33-39,47页

作者：周专苗帅袁铁江国网新疆电力有限公司新疆乌鲁木齐830011 大连理工大学电气工程学院辽宁大连116024

为预测“双碳”目标下氢能的需求,充分挖掘与氢能需求相关的影响因素,构建了基于系统动力学的交通领域氢能需求预测系统。绘制了交通领域氢能需求预测系统的因果关系图和系统流图,重点考虑公共汽车、重型卡车和家用汽车的氢能替代,通过... 详细信息

为预测“双碳”目标下氢能的需求,充分挖掘与氢能需求相关的影响因素,构建了基于系统动力学的交通领域氢能需求预测系统。绘制了交通领域氢能需求预测系统的因果关系图和系统流图,重点考虑公共汽车、重型卡车和家用汽车的氢能替代,通过历史数据检验模型的有效性,以新疆地区为例,设置低速、中速、高速3个发展水平来分析政策支持和经济投入对交通领域氢能需求的影响。模拟结果表明,交通领域的转型在2030年前发展得较为缓慢,政策和经济投资的影响在之后会逐渐明显,发展水平越高各类交通工具的增长幅度会越来越大,至2050年高速发展水平下的平均氢能替代率会达到低速发展水平下的2.2倍,高速发展水平下的售氢回报会达到低速发展水平下的2.5倍。

关键词：交通领域系统动力学需求预测发展水平分析氢能替代

在线全文

学校读者我要写书评

暂无评论

行政事业单位经济责任审计风险初探

山西财经大学学报 2024年第S1期46卷 193-195页

作者：雷转芳兰州市劳动保障监察支队甘肃兰州730030

经济责任审计是最具有中国特色的审计形式之一,也是我国审计工作重要的方法和手段。随着我国行政体系的不断发展,经济责任审计在行政事业单位中的重要性也被不断强调和重视。本文论述了行政事业单位经济责任审计风险的内涵、特点及意义... 详细信息

经济责任审计是最具有中国特色的审计形式之一,也是我国审计工作重要的方法和手段。随着我国行政体系的不断发展,经济责任审计在行政事业单位中的重要性也被不断强调和重视。本文论述了行政事业单位经济责任审计风险的内涵、特点及意义,分析了行政事业单位经济责任审计风险的内容及形成原因,最后提出了行政事业单位经济责任审计风险控制的对策。

关键词：行政事业单位经济责任审计对策

Preparation and properties of C/C-SiC brake composites fabricated by warm compacted-in situ reaction

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2010年第4期17卷 500-505页

作者： zhuan Li Peng Xiao Xiang xiong State Key Laboratory of Powder Metallurgy Central South University Changsha 410083 China

Carbon fibre reinforced carbon and silicon carbide dual matrix composites（C/C-SiC） were fabricated by the warm compacted-in situ *** microstructure,mechanical properties,tribological properties,and wear mechanism of C/C-SiC composites at different brake speeds were *** results indicate that the composites are composed of 58wt%C,37wt%SiC,and 5wt%*** density and open porosity are 2.0 ***^（-3） and 10%,*** C/C-SiC brake composites exhibit good mechanical *** flexural strength can reach up to 160 MPa,and the impact strength can reach 2.5 kJ.m^（-2）.The C/C-SiC brake composites show excellent tribological *** friction coefficient is between 0.57 and 0.67 at the brake speeds from 8 to 24 m·s^（-1）.The brake is stable,and the wear rate is less than 2.02×10^（-6） cm^3·J^（-1）.These results show that the C/C-SiC brake composites are the promising candidates for advanced brake and clutch systems.

关键词： C/C-SiC ceramic matrix composites tribological properties microstructure

Exploration of the Integration of Curriculum Ideology and Politics into the Educational Pathway of Standardized Training for General Practice Residents

在线全文

学校读者我要写书评

暂无评论

Journal of Contemporary Educational Research 2024年第5期8卷 91-96页

作者： zhuan Huang Yaodong Li Lina Ma Rui Xu Fang Yang Yingpeng Shi Junlin Liu The First Affiliated Hospital of Xi’an Medical University Xi’an 710077Shaanxi ProvinceChina School of Foreign Languages Xi’an Medical UniversityXi’an 710077Shaanxi ProvinceChina

In recent years,the national higher education reform has proposed the concept of curriculum ideological and political education as a major *** integration into the standardized training of general practice residents(commonly referred to as general resident training)is an unavoidable trend in the teaching *** on the actual situation of our unit at The First Affiliated Hospital of Xi’an Medical University,this paper emphasizes the necessity of incorporating ideological and political education into the general resident training curriculum,despite the absence of pertinent practical experience in how to effectively incorporate such courses into comprehensive residential *** our hospital,we must assess the ideological and political education in the curriculum of general resident training,proposing a scientific,reasonable ideological and political education concept system for general practice courses,integrating ideological and political education with general practice resident training,and strengthening the team of ideological and political education physicians to teach them to carry out such education,this would foster enthusiasm and *** admission education and training for general practice resident training,as well as regularly hosting symposiums to share ideas and understand the mission of doctors can provide effective experience for ideological and political education in general resident training courses.

关键词： Curriculum ideological and political education General practice General practice residents Standardized training Education path Exploration

香溪河消落带土壤重金属的生态及健康风险评价及预测

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

武汉大学学报（理学版） 2024年第1期70卷 87-95页

作者：张家璇鄢文苗毛祥虎靳专胥焘熊彪三峡大学湖北省农田环境监测工程技术研究中心湖北宜昌443002 三峡大学三峡库区生态环境教育部工程研究中心湖北宜昌443002 三峡大学计算机与信息学院湖北宜昌443002 三峡大学生物与制药学院湖北宜昌443002

采集三峡库区香溪河消落带2020—2022年不同季节、不同高程的土壤样品,测定其中4种重金属元素(Cu、Pb、Cd、Cr)含量,进行生态及健康风险评价。地积累指数结果表明,Cd为研究区域主要污染元素,处于轻度污染等级,其他3种元素处于无污染等... 详细信息

采集三峡库区香溪河消落带2020—2022年不同季节、不同高程的土壤样品,测定其中4种重金属元素(Cu、Pb、Cd、Cr)含量,进行生态及健康风险评价。地积累指数结果表明,Cd为研究区域主要污染元素,处于轻度污染等级,其他3种元素处于无污染等级。潜在生态风险指数结果表明,研究区域整体为轻度生态风险,但在27%的土壤样品中,Cd元素的潜在生态风险指数属于中强度风险。重金属健康风险结果表明,研究区域重金属的非致癌风险与致癌风险均处于可接受水平,儿童的致癌风险高于成人。使用支持向量机(SVM)模型对土壤重金属含量进行基于时间序列和季节变化的定量预测。结果表明:基于时间序列的模拟实验中,SVM对上层土中重金属元素含量的预测较为准确;基于季节变化的模拟实验中,SVM对上、下层土的重金属元素含量均能很好地拟合。

关键词：三峡库区支持向量机消落带重金属预测

在线全文

学校读者我要写书评

暂无评论

提升风电消纳的绿氢钢铁冶炼系统动力学建模

中国电力 2024年第8期57卷 36-45页

作者：周专苗帅袁铁江国网新疆电力有限公司新疆乌鲁木齐830011 大连理工大学电气工程学院辽宁大连116024

富裕风电电解水制氢,耦合高污染的钢铁冶炼过程,既促进炼钢产业低碳转型,又可有效提升风电消纳能力。为了模拟绿氢钢铁冶炼对风电消纳能力的影响,综合考虑钢铁冶炼的可靠性、氢能发展的经济性以及风力发电的环境性,确定绿电-氢能-钢铁... 详细信息

富裕风电电解水制氢,耦合高污染的钢铁冶炼过程,既促进炼钢产业低碳转型,又可有效提升风电消纳能力。为了模拟绿氢钢铁冶炼对风电消纳能力的影响,综合考虑钢铁冶炼的可靠性、氢能发展的经济性以及风力发电的环境性,确定绿电-氢能-钢铁冶炼耦合系统内部交互关系和反馈机制;结合钢铁行业发展趋势和绿氢替代潜力,建立了提升风电消纳的绿氢钢铁冶炼系统动力学模型;同时考虑到政府支持力度与制氢技术的发展,构建差异化情景,分析不同条件下的氢能需求规模和风电消纳水平。基于新疆案例表明,加大氢冶金支持力度和提高制氢电解效率,能够有效提升钢铁行业的绿氢替代率并加速绿氢成本降低,进而实现风电的全额消纳,有效解决“弃风”难题。

关键词：风电消纳绿氢需求钢铁行业清洁冶炼系统动力学

同方期刊数据库

三峡库区消落带植被NPP估算——基于机器学习优化CASA模型

在线全文

学校读者我要写书评

暂无评论

生态学报 2024年第6期44卷 2464-2478页

作者：靳专胥焘黄应平肖敏张家璇周爽爽席颖熊彪湖北省农田环境监测工程技术研究中心(三峡大学) 宜昌443002 三峡大学计算机与信息学院宜昌443002 三峡库区生态环境教育部工程研究中心(三峡大学) 宜昌443002 三峡大学水利与环境学院宜昌443002

三峡库区蓄水后,其生态效应受到广泛关注。消落带植被固碳量作为衡量库区生态系统健康状态的重要指标,对库区碳循环与生态净化具有重要意义。针对消落带不同高程植被接受光照的时间有所差异,且受河流水位变化影响,传统的CASA模型在计算... 详细信息

三峡库区蓄水后,其生态效应受到广泛关注。消落带植被固碳量作为衡量库区生态系统健康状态的重要指标,对库区碳循环与生态净化具有重要意义。针对消落带不同高程植被接受光照的时间有所差异,且受河流水位变化影响,传统的CASA模型在计算消落带植被固碳量时,存在对植物的光能利用率计算不够精确等问题。以三峡库区香溪河陡坡消落带为研究区域,提出了一种耦合RBFNN模型(Radial Basis function Neural Network)与CASA模型(Carnegie-Ames-Stanford approach)的新方法(RBF-CASA)。基于RBFNN建立环境影响因子模型,借助高程数据及植被指数等特征计算适合消落带区域的环境影响因子。结合CASA模型中温度和水分胁迫因子,提高植被在像元尺度上的净初级生产力(Net Primary Productivity,NPP)的估算精度,并对反演结果进行验证。模型验证结果显示:RBF-CASA模型估算值与观测值的决定系数(Coefficient of determination,R^(2))为0.730(P<0.01,n=32)。对比原始CASA模型,平均绝对误差(Mean absolute error,MAE)降低10.991,均方根误差(Root mean square error,RMSE)降低了23.861,相对均方根误差(Relative root mean square error,RRMSE)降低5.10%,平均绝对百分误差(Mean absolute percentage error,MAPE)降低1.12%。使用提出的RBF-CASA模型在库区水位落干期(7—8月份)进行固碳量估算,结果表明:NPP月均值在66.234—134.144g C/m^(2)之间,NPP随着高程的增加呈现起伏变化,其总量在150—155m之间达到峰值,均值在170m以上区域最高。在2021年9月植被NPP均值为35.883g C/m^(2),2022年9月植被NPP均值为25.964g C/m^(2),由于降雨量减少、长江水位下降,在2021—2022年间植被恢复情况较差。研究结果可为库区碳循环、生态净化及生态修复等决策提供科学依据。

关键词：基于过程的遥感模型(CASA) 机器学习植被净初级生产力(NPP) 无人机环境影响因子模型