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中国皮革 2006年第19期35卷 45-48页

作者：杨伟福温祖谋上海富国皮革有限公司上海200436 上海市皮革技术协会上海200023

本课题旨在研讨制革企业所普遍存在的潜在危害和从业人员的职业健康,并针对现实状况与发展趋势,探讨制革企业若干必要的安全防护措施以及如何建立、完善安全健康体系,进而提出制革行业所必须面对的社会责任。

关键词：制革潜在危害职业健康安全防护

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GIS属性数据库的关系模式分解研究

陕西师大学报（自然科学版） 2000年第2期28卷 93-98页

作者：付炜新疆大学电子信息科学系新疆乌鲁木齐830046

讨论了GIS属性数据库设计中关系模式的构造原理和方法 .在GIS的数据库模式设计中 ,地理实体的关系模式分解是属性数据库应用设计的关键 .在对GIS属性数据库的特征分析基础上 ,讨论了地理实体的关系模式的分解表示及其应遵循的约束条件 ... 详细信息

讨论了GIS属性数据库设计中关系模式的构造原理和方法 .在GIS的数据库模式设计中 ,地理实体的关系模式分解是属性数据库应用设计的关键 .在对GIS属性数据库的特征分析基础上 ,讨论了地理实体的关系模式的分解表示及其应遵循的约束条件 ,即信息无损失连接特性和保持函数依赖特性 .在关系模式的分解表示中 ,将地理实体错综复杂的关系模式分解成一组简单的属性关系集合 .同时 ,为使分解过程中不出现信息丢失并维护地学数据的完整性约束 ,还讨论了关系模式分解应满足的信息无损失连接性的约束条件 ,以及关系模式分解所应保持的函数依赖的约束因素 .

关键词：属性数据库关系模式模式分解 GIS

Intermittent appearance of right coronary fistula and collateral circulation:A case report

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World Journal of Clinical Cases 2021年第28期9卷 8504-8508页

作者： wen-Jie Long Xi Huang Yuan-Hong Lu Hao-Ming Huang Guo-wei Li Xia Wang Zhi-Ling He Department of Geriatrics The First Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou 510006Guangdong ProvinceChina The First Clinical Medical College Guangzhou University of Chinese MedicineGuangzhou 510006Guangdong ProvinceChina Department of Radiology The First Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou 510006Guangdong ProvinceChina Department of Emergency Guangdong Provincial Hospital of Chinese MedicineGuangzhou 510000Guangdong ProvinceChina Department of Cardiovascular Guangdong Provincial Hospital of Chinese MedicineGuangzhou 510000Guangdong ProvinceChina Department of Cardiovascular Guangdong Provincial Hospital of Chinese MedicineGuangzhou 510006Guangdong ProvinceChina

BACKGROUND Congenital coronary artery fistula can lead to symptoms of chest tightness,chest pain,or exertional dyspnea,which is a congenital vascular malformation that should not be *** who have such malformations are frequently observed with different concurrent abnormal anatomic *** circulation may have a positive effect on improving the patients'*** SUMMARY A 53-year-old female experienced episodic chest discomfort for the past month with symptoms manifesting when she was agitated or *** a positive treadmill test,the patient underwent coronary angiography.“Ghostlike”intermittent appearance of coronary ventricular fistula and collateral branching were *** patient was diagnosed with a right coronary ventricular fistula and collateral *** This case shows the likelihood of collateral circulation in patients with coronary artery *** may provide medical staff with novel solutions to treat insufficiency of myocardial blood supply induced by cardiovascular malformations.

关键词： Coronary fistula Collateral circulation Congenital coronary artery Case report

A NEW METHOD OF DETERMING SOURCE TERMS OF POISSON EQUATIONS FOR GRID GENERATION

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Journal of Hydrodynamics 2000年第1期12卷 16-21页

作者： wei wen li, Wang De yi, Zhang Zong xiao, Liu Yu ling Xi′an University of Technology, Xi′an 710048, P.R.China Xi'an Univ of Technology Xi'an China

This paper is concerned with a new method to determine the source terms P and Q of Poisson equations for grid generation, with which a satisfactory grid can be obtained. The interior grid distribution is controlled by the prior selection of grid point distribution along the boundary of the region, and the orthogonality condition in the neighborhood of the boundary is satisfied. This grid generation technique can be widely used in the numerical solution of 2 D flow in rivers, lakes, and shallow water regions.

关键词： Poisson equations grid generation weighting functions

Origin of High Efficiency and Long-Term Stability in Ionic Liquid Perovskite Photovoltaic

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Research 2020年第1期2020卷 391-403页

作者： Lingfeng Chao Tingting Niu Hao Gu Yingguo Yang Qi wei Yingdong Xia wei Hui Shouwei Zuo Zhaohua Zhu Chengjie Pei Xiaodong Li Jing Zhang Junfeng Fang Guichuan Xing Hai Li Xiao Huang Xingyu Gao Chenxin Ran Lin Song Li fu Yonghua Chen wei Huang Frontiers Science Center for Flexible Electronics Xi’an Institute of Flexible Electronics(IFE)and Xi’an Institute of Biomedical Materials&EngineeringNorthwestern Polytechnical University127 West Youyi RoadXi’an 710072China Key Laboratory of Flexible Electronics(KLOFE)&Institution of Advanced Materials(IAM) Nanjing Tech University(Nanjing Tech)Nanjing211816 JiangsuChina Shanghai Synchrotron Radiation Facility Shanghai Institute of Applied PhysicsChinese Academy of SciencesShanghai 201204China Beijing Synchrotron Radiation Facility Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China School of Physics and Electronic Science Ministry of EducationNanophotonics&Advanced Instrument Engineering Research CenterEast China Normal UniversityShanghai 200062China Institute of Applied Physics and Materials Engineering University of MacaoMacaoMacao SAR 999078China Key Laboratory for Organic Electronics&Information Displays(KLOEID)and Institute of Advanced Materials(IAM) Nanjing University of Posts and TelecommunicationsNanjing210023 JiangsuChina

Environment-friendly protic amine carboxylic acid ionic liquids(ILs)as solvents is a significant breakthrough with respect to traditional highly coordinating and toxic solvents in achieving efficient and stable perovskite solar cells(PSCs)with a simple one-step air processing and without an antisolvent treatment ***,it remains mysterious for the improved efficiency and stability of PSCs without any passivation ***,we unambiguously demonstrate that the three functions of solvents,additive,and passivation are present for protic amine carboxylic acid *** found that the ILs have the capability to dissolve a series of perovskite precursors,induce oriented crystallization,and chemically passivate the grain *** is attributed to the unique molecular structure of ILs with carbonyl and amine groups,allowing for strong interaction with perovskite precursors by forming C=O…Pb chelate bonds and N-H…I hydrogen bonds in both solution and *** finding is generic in nature with extension to a wide range of IL-based perovskite optoelectronics.

关键词： perovskite bonds breakthrough

Novel organometallic aromatic polyester based on ferrocene

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Chinese Chemical Letters 2010年第6期21卷 748-752页

作者： wei Key Laboratory of Applied Technology of Polymer Materials The Education Department of Liaoning ProvinceShenyang Institute of Chemical TechnologyShenyang 110142China School of Environmental Science Liaoning UniversityShenyang 110036China Department of Polymer Science & Materials Dalian University of TechnologyDalian 116012China

A novel polyester containing ferrocenyl was prepared by low-temperature interface polycondensation of 1,1'-ferrocenedicarboxylic acid chloride with 4-(4-hydroxyphenyl)-2,3-phthalazin-1-one(DHPZ),which is a twisted non-coplanar heterocyclic bisphenol-like *** newly generated polymer was evaluated based on characterization of its solubility,viscosity measurements,elemental analysis,FTIR spectroscopy,differential scanning calorimetric and thermogravimetric studies.

关键词： Ferrocene Polyester Organometallic Thermal property

Design, synthesis and systematic evaluation of all possible cyclic dinucleotides (CDNs) that activate human stimulator of interferon genes (STING) variants

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Science China Chemistry 2020年第4期63卷 534-545页

作者： Zheng-Hua Wang Can-Can Zhao Qiang-Zhe Zhang Chuan-Lin Wang Hang Zhang De-Jun Ma Da-wei Wang Xin wen Lu-Yuan Li Zhen Xi State Key Laboratory of Elemento-organic Chemistry Department of Chemical BiologyCollege of ChemistryNankai UniversityTianjin 300071China State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy Tianjin Key Laboratory of Molecular Drug ResearchNankai UniversityTianjin 300071China Collaborative Innovation Center of Chemical Science and Engineering(Tianjin) Tianjin 300071China National Pesticide Engineering Research Center(Tianjin) Tianjin 300071China

Cyclic dinucleotides(CDNs) are known to activate stimulator of interferon genes(STING) and induce type I interferon responses, therefor possess great potentials to be of immunotherapeutic value for cancers and infectious diseases. However, the existence of different single nucleotide polymorphism(SNP) of human STING(hSTING) gene poses an obstacle to achieve broad-spectrum activation by CDNs. We reported here the design and synthesis of a total of 36 CDNs, representing all structural variations, that contain four bases(A, G, C, U) and two linkage directions(2′-5′-linked and 3′-5′-linked phosphodiester).Through systematic evaluation of IFN-β induction with a dual-luciferase reporter assay, we discovered that wild type hSTING and two isoforms(HAQ and AQ) showed strong response while hSTING-R232 H and R293 Q exhibited the relatively weak response to CDNs stimulation. For the first time, we found that the c[G(2′,5′)U(2′,5′)] showed excellent activity against all five hSTING variants even equivalent to the endogenous ligand c[G(2′,5′)A(3′,5′)]. furthermore, we have also demonstrated that 3′-3′CDNs with two 3′-5′ phosphodiesters showed higher serum and hydrolase stability than 2′-2′ CDNs with two 2′-5′ phosphodiesters and 2′-3′ CDNs with one 2′-5′ and one 3′-5′ phosphodiester. It is very interesting to note that 2′-2′ CDNs has been found for the first time to show strong activity. These findings will stimulate our exploration for the new functional role of CDNs, and provide guidelines to design CDNs based hSTING targeted drugs.

关键词： cyclic dinucleotides(CDNs) stimulator of interferon genes(STING) pyrimidine CDNs interferonβ ecto-nucleotide pyrophosphatase/phosphodiesterase 1(ENPP1)

Spatiotemporal expression of leukemia inhibitory factor receptor protein during neural tube development in embryos with neural tube defects

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Neural Regeneration Research 2020年第4期15卷 705-711页

作者： Dong An Xiao-wei wei He-Nan Zhang Dan Liu wei Ma Zheng-wei Yuan Key Laboratory of Health Ministry for Congenital Malformation Shengjing HospitalChina Medical UniversityShenyangLiaoning ProvinceChina Department of Pediatrics The First Hospital of China Medical UniversityShenyangLiaoning ProvinceChina

Leukemia inhibitory factor receptor(LIFR),as a neuroregulatory cytokine receptor,generally shows a neuroprotective effect in central nervous system *** this study,to understand the effect of LIFR on pathogenesis of neural tube defects,we explored spatiotemporal expression of LIFR at different stages of fetal development in normal and neural tube defect *** bifida aperta was induced with all-trans retinoic acid on embryonic day 10 in rats,and the spatiotemporal expression of LIFR was investigated in spina bifida aperta rats and healthy rats from embryonic day 11 to *** time-polymerase chain reaction and western blot assay were used to examine mRNA and protein expression of LIFR in healthy control and neural tube defect *** of the animal experiment demonstrated that expression of LIFR protein and mRNA in the spinal cords of normal rat embryos increased with embryonic *** was significantly downregulated in the spinal cords of spina bifida aperta rats compared with healthy rats from embryonic days 11 to *** staining showed that the expression of LIFR in placenta and spinal cord in spina bifida aperta rat embryos was decreased compared with that in control embryos at embryonic day *** from human embryo specimens showed that LIFR mRNA expression was significantly down-regulated in spinal cords of human fetuses with neural tube defects compared with normal controls at a gestational age of 24 to 33 *** results were consistent with the down-regulation of LIFR in the animal *** study revealed spatiotemporal changes in expression of LIFR during embryonic ***,LIFR might play a specific role in neural tube *** animal and human experimental procedures were approved by the Medical Ethics Committee of Shengjing Hospital of China Medical University,China(approval No.2016PS106K)on February 25,2016.

关键词： amniotic fluid development embryogenesis leukemia inhibitory factor receptor nerve regeneration neural tube defect placenta spatiotemporal expression spina bifida aperta spinal cord serum

Low-thermal-conductivity thermal barrier coatings with a multi-scale pore design and sintering resistance following thermal exposure

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Rare Metals 2020年第4期39卷 352-367页

作者： wei-wei Zhang Zhi-Yuan wei Li-Yuan Zhang Ya-Zhe Xing Qiang Zhang School of Materials Science and Engineering Chang'an UniversityXi'an 710064China State Key Laboratory for Mechanical Behavior of Materials School of Materials Science and EngineeringXi’an Jiaotong UniversityXi'an 710049China College of Chemistry and Chemical Engineering Neijiang Normal UniversityNeijiang 641112China AECC Beijing Institute of Aeronautical Material Beijing 100095China

High-insulation,long-life thermal barrier coatings(TBCs)decrease the service temperature of superalloys and improve the service life of gas *** in the thermal insulation properties of the coating mainly depends on the optimization of the TBC *** important challenge for TBCs is maintaining a high performance during thermal exposure without degradation,as the pore-rich structure of the topcoat would inevitably be transformed by sintering.A low-thermalconductivity anti-sintering coating can overcome the tradeoff between thermal insulation and sinter *** this review,the design,preparation,and serviceability evaluation of a low-thermal-conductivity anti-sintering coating will be ***,directions for potential development are *** paper provides a comprehensive understanding of the structured tailoring of TBCs for better thermal insulation and anti-sintering performance.

关键词： Thermal barrier coatings Multi-scale pore Sintering resistance Low thermal conductivity

Local resonance phononic band gaps in modifiedtwo-dimensional lattice materials

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Acta Mechanica Sinica 2012年第3期28卷 659-669页

作者： wei Liu Ji-wei Chen Xian-Yue Su LTCS and Department of Mechanics and Aerospace Engineering College of EngineeringPeking University100871 BeijingChina

In this paper, modified two-dimensional peri- odic lattice materials with local resonance phononic band gaps are designed and investigated. The design concept is to introduce some auxiliary structures into conventional pe- riodic lattice materials. Elastic wave propagation in this kind of modified two-dimensional lattice materials is studied us- ing a combination of Bloch＇s theorem with finite element method. The calculated frequency band structures of illus- trative modified square lattice materials reveal the existence of frequency band gaps in the low frequency region due to the introduction of the auxiliary structures. The mechanism underlying the occurrence of these frequency band gaps is thoroughly discussed and natural resonances of the auxiliary structures are validated to be the origin. The effect of geo- metric parameters of the auxiliary structures on the width of the local resonance phononic band gaps is explored. Finally, a conceptual broadband vibration-insulating structure based on the modified lattice materials is designed and its capabil- ity is demonstrated. The present work is anticipated to be useful in designing structures which can insulate mechanical vibrations within desired frequency ranges.

关键词： Modified lattice materials Bloch's theoremLocal resonance phononic band gaps Vibration insulation