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Through-polymer,via technology-enabled,flexible,lightweight,and integrated devices for implantable neural probes

Microsystems & Nanoengineering 2024年第2期10卷 279-291页

作者： Cunkai Zhou Ye Tian Gen Li Yifei Ye Lusha Gao Jiazhi Li Ziwei Liu Haoyang Su Yunxiao Lu Meng Li Zhitao Zhou Xiaoling wei Lunming Qin Tiger H.Tao Liuyang Sun College of Electronics and Information Engineering Shanghai University of Electric PowerShanghaiChina 2020 X-Lab Shanghai Institute of Microsystem and Information TechnologyChinese Academy of SciencesShanghaiChina School of Graduate Study University of Chinese Academy of SciencesBeijingChina State Key Laboratory of Transducer Technology Shanghai Institute of Microsystem and Information TechnologyChinese Academy of SciencesShanghaiChina Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijingChina School of Physical Science and Technology ShanghaiTech UniversityShanghaiChina Center for Excellence in Brain Science and Intelligence Technology Chinese Academy of SciencesShanghaiChina Neuroxess Co. Ltd.(Jiangxi)NanchangJiangxiChina Guangdong Institute of Intelligence Science and Technology HengqinZhuhaiGuangdongChina Tianqiao and Chrissy Chen Institute for Translational Research ShanghaiChina

In implantable electrophysiological recording systems,the headstage typically comprises neural probes that interface with brain tissue and integrated circuit chips for signal *** advancements in MEMS and CMOS technology have significantly improved these components,their interconnection still relies on conventional printed circuit boards and sophisticated *** conventional approach adds considerable weight and volume to the package,especially for high channel count *** address this issue,we developed a through-polymer via(TPV)method inspired by the through-silicon via(TSV)technique in advanced three-dimensional *** innovation enables the vertical integration of flexible probes,amplifier chips,and PCBs,realizing a flexible,lightweight,and integrated device(FLID).The total weight of the FLIDis only 25%that of its conventional counterparts relying on adapters,which significantly increased the activity levels of animals wearing the FLIDs to nearly match the levels of control animals without ***,by incorporating a platinum-iridium alloy as the top layer material for electrical contact,the FLID realizes exceptional electrical performance,enabling in vivo measurements of both local field potentials and individual neuron action *** findings showcase the potential of FLIDs in scaling up implantable neural recording systems and mark a significant advancement in the field of neurotechnology.

关键词： alloy neural recording

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pH-controlled reversible sol-gel inversion by cerous phosphate nanofibers for hemostasis

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Rare Metals 2024年第10期43卷 5141-5151页

作者： Tuo Su Jun-Chen Xu wei Yu Dan Su Di-Er Shi Yi-Chao Pang Yao Ying Wang-chang Li Juan Li Jing-Wu Zheng Liang Qiao Sheng-Lei Che Jing Yu Research Center of Magnetic and Electronic Materials College of Materials Science and EngineeringZhejiang University of Technology State Key Laboratory for Diagnosis and Treatment of Infectious Diseases Collaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesThe First Affiliated HospitalCollege of MedicineZhejiang University Key Laboratory of Drug Safety Evaluation and Research of Zhejiang Province Department of Clinical MedicineHangzhou Medical College Department of Chemistry Zhejiang University Clinical Medical College Yangzhou University

Developing biomimetic soft materials that display stimuli responsiveness using solely inorganic materials has been regarded as a challenge owing to that such materials?properties typically vary from those of living ***,biomimetic soft materials have been developed using organic materials or inorganic materials modified with organic small *** this study,we prepared cerium phosphate nanofibers （CePO4NFs） by using inorganic agents only without further *** CePO4NFs demonstrate sol-ge switching properties in response to pH value,allowing them to form a gel under high hydroxide ion （OH-） concentrations and turn back into sol under low *** formation of gel could be ascribed to the physical cross-linking of the nanofibers induced by the attractive electrostatic force of OH-and surface Ce3+.As a result,CePO4NFs are able to form a gel when in contac with blood of high pH value for *** specific clotting mechanism makes them better candidates for hemostasis of heavy bleeding.

关键词： Cerium phosphate nanofibers Hemostasis pH-responsive Reversible Sol-gel switching

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An Application of BMO-type Space to Chemotaxis-fluid Equations

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Acta Mathematica Sinica,English Series 2023年第8期39卷 1650-1666页

作者： Ming Hua YANG Yu Mei ZI Zun wei fu Department of Mathematics Jiangxi University of Finance and EconomicsNanchang 330032P.R.China Department of Mathematics Linyi UniversityLinyi 276005P.R.China College of Information Technology The University of SuwonBongdameupHwaseong-siGyeonggi-do445-743Korea

We consider a Keller–Segel model coupled to the incompressible Navier–Stokes system in 3-dimensional *** prove that the system has a unique local solution when(u0,n0,c0)∈Φ_(01)^(1)×Φ_(01)^(2)×Φ_(01)^(3),where Φ_(01)^(1)×Φ_(01)^(2)×Φ_(01)^(3) is a subspace of bmo^(−1)(R^(3))×B˙_(p,∞)^(−2+3/p) (R^(3))×(B˙_(q,∞)^(3/q) (R^(3))∩L^(∞)(R^(3))).furthermore,we obtain that the system exists a unique global solution for any small initial data(u0,n0,c0)∈BMO^(−1)(R^(3))×B˙_(p,∞)^(−2+3/p)(R^(3))×(B_(q,∞)^(3/q)(R^(3))∩L^(∞)(R^(3))).For the difference between these spaces and known ones,our results may be regarded as a new existence theorem on the system.

关键词： BMO-type space Fourier transform Besov space Keller-Segel equation Navier-Stokes equation

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印模法古地貌恢复在岩溶丘滩相有利区评价中的应用:以川中古隆起北斜坡灯影组二段为例

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科学技术与工程 2024年第15期24卷 6190-6198页

作者：徐敏巫芙蓉彭才臧殿光杨晋蓉罗伟孙甫董同武崔青雯东方地球物理公司西南物探研究院成都610213 东方地球物理公司研究院涿州072750

四川盆地寒武系-震旦系裂陷槽东侧川中古隆起北斜坡灯影组二段岩溶丘滩相储层非均质性强,主控因素复杂,成为制约北斜坡地区下一步天然气勘探目标优选的关键因素。利用三维连片地震数据,基于最新探井钻井、测井等资料,创新思路,提出用灯... 详细信息

四川盆地寒武系-震旦系裂陷槽东侧川中古隆起北斜坡灯影组二段岩溶丘滩相储层非均质性强,主控因素复杂,成为制约北斜坡地区下一步天然气勘探目标优选的关键因素。利用三维连片地震数据,基于最新探井钻井、测井等资料,创新思路,提出用灯影组沉积后期的岩溶地貌来刻画滩相储层有利区,把上覆地层沧浪铺底作为基准层,采用印模法进行微幅古地貌分析,刻画了灯二岩溶期地貌特征。在此基础上,精细研究了储层的地震响应特征,建立了地震相分类模式,利用波形分类方法进行岩溶丘滩相储层发育有利区预测。成果揭示灯二段岩溶丘滩相储层发育规律呈与侵蚀槽展布方向相同的北西-南东向展布,与实际钻井和地质认识一致。相较之常规用的残厚法,该方法更加考虑了沉积特征和地质规律,减少了地震预测的多解性,且可达到半定量预测效果,为古隆起北斜坡单斜构造背景下研究岩溶滩相储层有利区提供了有利指导。

关键词：川中古隆起岩溶丘滩相储层古地貌恢复术印模法地震相分析技术

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Surface engineering on MnO_(2)nanorods by La single atoms to accelerate oxygen reduction kinetics

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Rare Metals 2024年第9期43卷 4302-4311页

作者： Zhang-Long He Liu-Qi Wang Min Jiang Jia-Nan Xie Shan Liu Jin-Can Ren Rui Sun Wen-Bin Lv wei-Bin Guo Yu-Ling Liu Bing Li Qi Liu Hao He School of Materials Science and Engineering Changsha University of Science and TechnologyChangsha 410000China School of Materials Science and Engineering Nanjing University of Science and TechnologyNanjing 210094China School of Materials Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China Department of Physics City University of Hong KongHong Kong 999077China

Surface engineering,which modulates the electronic structure and adsorption/desorption properties of electrocatalysts,is one of the key strategies for improving the catalytic ***,we demonstrate a facile solid-phase reaction for surface engineering of MnO_(2)to boost the oxygen reduction *** reaction with surface hydroxy groups,La single atoms with loading amount up to 2.7 wt%are anchored onto a-MnO_(2)*** surface engineering,the oxygen reduction reaction(ORR)kinetics is significantly improved with the half-wave potential from 0.70 to 0.84 V,the number of transferred electrons from 2.5 to 3.9 and the limiting current density from 4.8 to 6.0 mA·cm^(-2).In addition,the catalyst delivers superior discharge performance in both alkaline and neutral metal–air *** functional theory(DFT)calculations reveal that atomic La modulates the surface electronic configuration of MnO_(2),reduces its d-band center and thus lowers the OOH*and O*reaction energy *** work provides a new route for rational design of highly active electrocatalyst and holds great potential for application in various catalytic reactions.

关键词： Surface engineering Single atoms Electron injection Oxygen reduction reaction Metal-air batteries

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PE管道的爆破振动响应规律及灰色关联度分析

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工程爆破 2024年第1期30卷 110-118页

作者：段宝福于昭文徐伟善孙宗军张正欣山东科技大学山东青岛266590 江汉大学爆破工程湖北省重点实验室武汉430056 青岛瑞翰科技集团山东青岛266061

为了降低隧道爆破施工对既有埋地PE管道造成的振动危害,有必要在施工前了解影响管道振动效应的各种因素。根据现场实测数据,采用MIDAS GTS NX软件建立岩土体-隧道-PE管道三维数值模型,并将现场监测结果和数值模拟结果进行对比分析,验证... 详细信息

为了降低隧道爆破施工对既有埋地PE管道造成的振动危害,有必要在施工前了解影响管道振动效应的各种因素。根据现场实测数据,采用MIDAS GTS NX软件建立岩土体-隧道-PE管道三维数值模型,并将现场监测结果和数值模拟结果进行对比分析,验证数值模型的可靠性。分析得出:爆破振动作用下土体弹性模量、泊松比和管径的增加会使管道的最大振速增大;因为地表自由面叠加作用的原因,管道埋深的增加使管道最大振速先减小后增大。运用灰色关联度理论,确定了4种不同因素对管道振动效应的影响程度,主次关系为:土体弹性模量>管道埋深>土体泊松比>管道直径。准确地了解各因素对管道振动的影响程度能够更好的对隧道爆破施工时PE管道的安全性进行评估,为工程实际施工提供参考。

关键词：隧道爆破灰色关联度 PE管道振动响应

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Nutrition strategies to control post-weaning diarrhea of piglets: From the perspective of feeds

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Animal Nutrition 2024年第2期17卷 297-311页

作者： Qingsong Tang Tianyi Lan Chengyu Zhou Jingchun Gao Liuting Wu Haiyang wei Wenxue Li Zhiru Tang Wenjie Tang Hui Diao Yetong Xu Xie Peng Jiaman Pang Xuan Zhao Zhihong Sun Laboratory for Bio-Feed and Molecular Nutrition College of Animal Science and Technology Southwest University Animal Breeding and Genetics Key Laboratory of Sichuan Province Sichuan Animal Science Academy Yibin Academy of Southwest University

Post-weaning diarrhea(PWD) is a globally significant threat to the swine industry. Historically, antibiotics as well as high doses of zinc oxide and copper sulfate have been commonly used to control ***, the development of bacterial resistance and environmental pollution have created an interest in alternative strategies. In recent years, the research surrounding these alternative strategies and the mechanisms of piglet diarrhea has been continually updated. Mechanically, diarrhea in piglets is a result of an imbalance in intestinal fluid and electrolyte absorption and secretion. In general, enterotoxigenic Escherichia coli(ETEC) and diarrheal viruses are known to cause an imbalance in the absorption and secretion of intestinal fluids and electrolytes in piglets, resulting in diarrhea when Cl secretion-driven fluid secretion surpasses absorptive capacity. From a perspective of feedstuffs, factors that contribute to imbalances in fluid absorption and secretion in the intestines of weaned piglets include high levels of crude protein(CP), stimulation by certain antigenic proteins, high acid-binding capacity(ABC), and contamination with deoxynivalenol(DON) in the diet. In response, efforts to reduce CP levels in diets,select feedstuffs with lower ABC values, and process feedstuffs using physical, chemical, and biological approaches are important strategies for alleviating PWD in piglets. Additionally, the diet supplementation with additives such as vitamins and natural products can also play a role in reducing the diarrhea incidence in weaned piglets. Here, we examine the mechanisms of absorption and secretion of intestinal fluids and electrolytes in piglets, summarize nutritional strategies to control PWD in piglets from the perspective of feeds, and provide new insights towards future research directions.

关键词： Post-weaning diarrhea Fluid secretion Feed Nutritional regulation strategies Piglet

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不排水条件下颗粒破碎粗粒土的动力特性分析

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自然灾害学报 2024年第2期33卷 132-141页

作者：吕中英向波刘恩龙魏巍中铁二十局集团有限公司陕西西安710016 四川省公路规划勘察设计研究院有限公司四川成都610041 四川大学水力学与山区河流开发保护国家重点实验室水利水电学院四川成都610065

地震荷载作用下堆石等土料会发生颗粒破碎,从而导致其动力特性与不发生颗粒破碎的土料有很大的区别。为了探讨破碎粒状材料在循环荷载作用下的力学特性,对人工制备的粒状破碎土料进行了频率为1.0 Hz的循环加载固结不排水(consolidation ... 详细信息

地震荷载作用下堆石等土料会发生颗粒破碎,从而导致其动力特性与不发生颗粒破碎的土料有很大的区别。为了探讨破碎粒状材料在循环荷载作用下的力学特性,对人工制备的粒状破碎土料进行了频率为1.0 Hz的循环加载固结不排水(consolidation undrained,CU)三轴试验,试验围压为100、200、300、400 kPa。研究结果表明:试样均为压缩破坏,呈应变硬化型;且不同激振力下的轴向应变曲线分为三段,即初始骤升段、中间平衡段和最终破坏段,并且每一阶段的长短和试样的变化均有所不同;动孔压随循环振次增大而增大,且在相同围压下激振力越大动孔压上升得越快。对动强度曲线分析发现,应力比越小动强度曲线越低;阻尼比整体上随着动剪应变的增大而逐渐增大,并且相同围压下激振力越小则阻尼比越小。颗粒破碎的影响因素有激振力、围压和振次等共同作用,不同围压(激振力)下各因素的影响大小不一、此消彼长,且随着围压增大颗粒破碎程度均逐渐增大。

关键词：循环加载颗粒破碎动强度动应力应变

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Natural variation of GmFNSII-2 contributes to drought resistance by modulating enzyme activity in soybean

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The Crop Journal 2024年第2期12卷 529-539页

作者： Huihui Gao Pengcheng wei Yongzhe Gu Pengbin Tang Yifan Shen Lei Yang Linxin Dong Haowei Zheng Kuo Shu Mayamiko Masangano Bin Dong Long Miao Jiajia Li Lijuan Qiu Xiaobo Wang School of Agronomy Anhui Agricultural UniversityHefei 230036AnhuiChina State Key Laboratory of Crop Gene Resources and Breeding The National Key Facility for Crop Gene Resources and Genetic Improvement(NFCRI)/Key Laboratory of Crop Gene Resource and Germplasm Enhancement(MOA)Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China

As an essential crop that provides vegetable oil and protein,soybean(Glycine max(L.)Merr.)is widely planted all over the ***,the scarcity of water resources worldwide has seriously impacted on the quality and yield of *** address this,exploring excellent genes for improving drought resistance in soybean is *** this study,we identified natural variations of GmFNSII-2(flavone synthase II)significantly affect the drought resistance of *** sequence analysis of GmFNSII-2 in 632 cultivated and 44 wild soybeans nine haplotypes were *** full-length allele GmFNSII-2^(C),but not the truncated allele GmFNSII-2^(A) possessing a nonsense nucleotide variation,increased enzyme *** research found that GmDREB3,known to increase soybean drought resistance,bound to the promoter region of GmFNSII-2^(C).GmDREB3 positively regulated the expression of GmFNSII-2^(C),increased flavone synthase abundance and improved the drought ***,a singlebase mutation in the GmFNSII-2^(C) promoter generated an additional drought response element(CCCCT),which had stronger interaction strength with GmDREB3 and increased its transcriptional activity under drought *** frequency of drought-resistant soybean varieties with Hap 1(Pro:GmFNSII-2^(C))has increased,suggesting that this haplotype may be selected during soybean *** summary,GmFNSII-2^(C) could be used for molecular breeding of drought-tolerant soybean.

关键词： Drought stress Flavone synthase GmFNSII-2 Natural variation Drought response element

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Steel ladle exchange models during steelmaking and continuous casting process

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Journal of Iron and Steel Research International 2017年第6期24卷 617-624页

作者： Bang-fu Huang Nai-yuanTian Zhe Shi Zhi-wei Ma Faculty of Metallurgical and Energy Engineering Kunming University of Science and Technology Kunming 650093 YunnanChina Clean Metallurgy Key Laboratory of Complex Iron Resources Kunming 650093 Yunnan China School of Metallurgical and Ecological Engineering University of Science and Technology Beijing Beijing 100083 China

The models and influencing factors of steel ladles exchange during the steelmaking and continuous casting process of H steel plant were investigated. Based on analysis of the operation process and turnover time of steel ladles, relationship models for the turnover number, turnover rate, continuous casting number, number of ladles with additional turnover, and number of ladles without additional turnover were built. The turnover rules of steel ladles for one basic oxygen furnace （BOF） matching one continuous caster （CC） and two BOFs matching two CCs modes were simulated by using a Gantt chart. The models of steel ladle exchange were proposed for casting of a single CC and overlapping casting of two CCs. By analyzing the influencing factors, the following conclusions were drawn. The exchange ladle should not have the task of transporting liquid ste^l in the CC that stops casting earli- er. The end time of the empty ladle in the CC that stops casting earlier should be earlier than the start time of the full ladle in the CC that stops casting later. After evaluating the factors influencing the start casting time, turnover cycle, casting time, continuous casting number, and overlapping time, a prioritization scheme of steel ladle exchange was proposed based on the steel grade. First, the turn- over cycle and single heat casting time were determined; based on these, a reasonable ladle turnover number was calculated. Second, the turnover number and continuous casting number were optimized for maximizing the number of ladles without additional turnover. Lastly, to reduce the casting number during the overlapping time to be lower than the turnover number, the overlapping time was shortened.

关键词： SteelmakingContinuous castingSteel ladleExchange modelTurnover optimizationProduction scheduling

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