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Deep learning CNN-APSO-LSSVm.hybrid fusion m.del for feature optim.zation and gas-bearing prediction

Petroleum.Science 2024年第04期21卷 2329-2344页

作者： Jiu-Qiang Yang Nian-Tian Lin Kai Zhang Yan Cui Chao fu Dong Zhang College of Earth Sciences and Engineering Shandong University of Science and Technology Laboratory for m.rine m.neral Resources Qingdao National Laboratory for Marine Science and Technology Transportation Institute of Inner m.ngolia University Key Laboratory of Gas Hydrate Qingdao Institute of Marine Geology Ministry of Natural Resources

Conventional m.chine learning(Cm.) m.thods have been successfully applied for gas reservoir prediction. Their prediction accuracy largely depends on the quality of the sam.le data; therefore, feature optim.zation of the input sam.les is particularly im.ortant. Com.only used feature optim.zation m.thods increase the interpretability of gas reservoirs; however, their steps are cum.ersom., and the selected features cannot sufficiently guide Cm. m.dels to m.ne the intrinsic features of sam.le data efficiently. In contrast to Cm. m.thods, deep learning(DL) m.thods can directly extract the im.ortant features of targets from.raw data. Therefore, this study proposes a feature optim.zation and gas-bearing prediction m.thod based on a hybrid fusion m.del that com.ines a convolutional neural network(CNN)and an adaptive particle swarm.optim.zation-least squares support vector m.chine(APSO-LSSVm.. This m.del adopts an end-to-end algorithm.structure to directly extract features from.sensitive m.lticom.onent seism.c attributes, considerably sim.lifying the feature optim.zation. A CNN was used for feature optim.zation to highlight sensitive gas reservoir inform.tion. APSO-LSSVm.was used to fully learn the relationship between the features extracted by the CNN to obtain the prediction results. The constructed hybrid fusion m.del im.roves gas-bearing prediction accuracy through two processes of feature optim.zation and intelligent prediction, giving full play to the advantages of DL and Cm. m.thods. The prediction results obtained are better than those of a single CNN m.del or APSO-LSSVm.m.del. In the feature optim.zation process of m.lticom.onent seism.c attribute data, CNN has dem.nstrated better gas reservoir feature extraction capabilities than com.only used attribute optim.zation m.thods. In the prediction process, the APSO-LSSVm.m.del can learn the gas reservoir characteristics better than the LSSVm.m.del and has a higher prediction accuracy. The constructed CNN-APSO-LSSVm.m.de

关键词： m.lticom.onent seism.c data Deep learning Adaptive particle swarm.optim.zation Convolutional neural network Least squares support vector m.chine Feature optim.zation Gas-bearing distribution prediction

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A novel neuroprotective m.thod against ischem.c stroke by accelerating the drainage of brain interstitial fluid

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Science China Life Sciences 2024年第10期67卷 2213-2223页

作者： Jingge Lian Liu Yang Hanbo Tan Shaoyi Su Leonor Serrano Lopes Fangxiao Cheng Junhao Yan Yu fu Wanyi fu Zhaoheng Xie Jianfei Sun Jicong Zhang Zhiqian Tong Yajuan Gao Hongbin Han Departm.nt of Radiology Peking University Third Hospital Beijing Key Laboratory of m.gnetic Resonance Im.ging Technology Institute of m.dical Technology Peking University Health Science Center Departm.nt of Inform.tics Technical University of Munich Departm.nt of Anatom. and Histology School of Basic Medical SciencesPeking University Departm.nt of Neurology Peking University Third Hospital Departm.nt of Electronic Engineering Tsinghua University State Key Laboratory of Bioelectronics School of Biological Science and Medical EngineeringSoutheast University School of Biological Science and m.dical Engineering Beihang University Key Laboratory of Alzheim.r's Disease of Zhejiang Province Institute of AgingSchool of Mental HealthWenzhou Medical University Nm.A Key Laboratory for Evaluation of m.dical Im.ging Equipm.nt and Technique

Ischem.c stroke is a leading cause of death and disability worldwide. Inflam.atory response after stroke determ.nes the outcom. of ischem.c injury. A recent study has reported an efficient m.thod, epidural arterial im.lantation(EAI), for accelerating interstitial fluid(ISF)drainage, which provides a prom.sing strategy to clear pro-inflam.atory cytokines in the brain extracellular space(ECS). In this study, the m.thod of EAI was m.dified(m.EAI) to control its function of accelerating the ISF drainage at different tim. points following ischem.c attack. The neuroprotective effect of m.EAI on ischem.c stroke was evaluated with the transient m.ddle cerebral artery occlusion(tm.AO)rat m.del. The results dem.nstrated the accum.lation of IL-1β, IL-6, and TNF-α was significantly decreased by activating m.EAI at 7 d before and im.ediately after ischem.c attack in tm.AO rats, accom.anied with decreased infarct volum. and im.roved neurological function. This study consolidates the hypothesis of exacerbated ischem.c dam.ge by inflam.atory response and provides a new perspective to treat encephalopathy via brain ECS. further research is essential to investigate whether m.EAI com.ined with neuroprotective drugs could enhance the therapeutic effect on ischem.c stroke.

关键词： ischem.c stroke brain extracellular space interstitial fluid m.dified epidural arterial im.lantation

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Study on the spatial and tem.oral evolutionary characteristics of ozone concentration and the im.act of hum.n activities in China in 2019

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Acta Geochim.ca 2024年第05期43卷 985-995页

作者： Yongchun Wang Wang Zhang Yu'an Liu Yazhu Wang Yuting fu Zhaohui Feng Lingqing Wang School of Geography South China Normal University College of Urban and Environm.ntal Sciences Hunan University of Technology Nanjing Institute of Geography and Lim.ology Chinese Academy of Sciences Institute of Geographical Sciences and Natural Resources Research Chinese Academy of Sciences

Ozone （O3） pollution has a profound im.act on hum.n health,vegetation developm.nt,and the ecological environm.nt,m.king it a critical focus of global academ.c *** recent years,O3pollution in China has been on a steady rise,with ozone em.rging as the sole conventional pollutant to consistently increase in concentration without any *** study conducted a quantitative analysis of O3concentrations across 367 Chinese cities in 2019,exam.ning spatial autocorrelation and local clustering of O3levels,and investigated the diverse relationships between hum.n activity factors and *** seasonal fluctuation of O3exhibited the“m.type”pattern,with peak concentrations in winter and the lowest levels in *** center of O3pollution m.grated southeastward,with the area of highest concentration progressively shifting south along the eastern ***,O3concentration showed a strong positive correlation with population density,road freight volum.,and industrial em.ssions,suggesting that hum.n activities,vehicle em.ssions,and industrial operations are significant contributors to *** results provide com.rehensive inform.tion on the characteristics,causes,and occurrence m.chanism.of O3in Chinese cities that can be utilized by global governm.nt departm.nts to form.late strategies to prevent and control O3pollution.

关键词： Hum.n activities Ozone concentration Spatial heterogeneity Urban agglom.rations

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Synthesis of carbon quantum.dots decorating Bi_(2)m.O_(6) m.crospherical heterostructure and its efficient photocatalytic degradation of antibiotic norfloxacin

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Chinese Chem.cal Letters 2024年第8期35卷 373-378页

作者： m.ijuan Chen Liyun Zhao Xianjin Shi Wei Wang Yu Huang Lijuan fu Lijun m. School of Hum.n Settlem.nts and Civil Engineering Xi’an Jiaotong UniversityXi’an 710049China Key Lab of Aerosol Chem.stry and Physics State Key Laboratory of Loess and Quaternary Geology(SKLLQG)Institute of Earth EnvironmentChinese Academy of SciencesXi’an 710061China

In this study,three-dim.nsional m.crospherical CQDs/Bi_(2)m.O_(6)heterostructures were synthesized using a sim.le alcohol-therm.l *** was found that the CQDs/Bi_(2)m.O_(6)had a large specific surface area of 56.0 m.(2)/g,and the introduction of CQDs extended the light absorption spectrum.from.480 nm.to 496 *** utilizing the synthesized CQDs/Bi_(2)m.O_(6)com.osite for photocatalytic degradation of antibiotic nor-floxacin in a water environm.nt,com.lete decay of norfloxacin and effective rem.val of total organic car-bon(TOC)were achieved within 30 *** the optim.zation of m.terial synthesis and experim.n-tal conditions,the optim.l CQDs loading am.unt was determ.ned as 200μL,the optim.l CQDs/Bi_(2)m.O_(6)dosage was 0.8 g/***,the CQDs/Bi_(2)m.O_(6)worked well under a wide pH range of *** co-existence of HCO_(3)−enhanced the norfloxacin decay,while the presence of Cl^(−),NO_(3)^(−),and SO_(4)^(2−)slightly retarded *** synthesized CQDs/Bi_(2)m.O_(6)had the great potential in rem.ving and m.neralizing nor-floxacin in real aquatic environm.nts.

关键词： Bi_(2)m.O_(6) CQDs Heterojunction Norfloxacin Photocatalysis

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Precise im.obilization of m.tal single atom. into a porphyrinic m.tal-organic fram.work for an efficient alkene hydrosilylation

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Nano Research 2024年第7期17卷 5914-5921页

作者： Chun-Ying Chen Qi-Jie m. fu-Zhen Li Hai-Li Song Li Zhang m.E Laboratory of Bioinorganic and Synthetic Chem.stry Lehn Institute of Functional MaterialsSchool of ChemistrySun Yat-Sen UniversityGuangzhou 510006China

Alkene hydrosilylation is one of the m.st concise and atom.econom.cal m.thods to synthesize organosilicon ***,we reported the precise im.obilization of m.tal single atom.(m.SAs;m.Ru,Rh,Ir,Pd,Pt,and Au)into a porphyrinic m.talorganic fram.work(m.F)of PCN-222(PCN=porous coordination network),and then applied the resultant m.F com.osites of m.SAs@PCN-222 to alkene *** solvent-free conditions,Pt-SAs@PCN-222 displayed an especially high catalytic efficiency with the turnover frequency up to 119 s−1 and the m.xim.m.turnover num.er of 906,250 at room.*** and theoretical studies revealed that there existed strong interactions between Pt-SAs@PCN-222 and the substrates,which helped to condense the substrates in the cavities of the porous *** density functional theory calculations and m.lecular dynam.cs sim.lations disclosed that PCN-222 could transfer electrons to Pt-SAs to enhance the silane oxidative addition and drive the reaction to proceed sm.othly via Chalk–Harrod pathway.

关键词： alkene hydrosilylation single atom.catalysts m.tal-organic fram.works precision chem.stry synergistic catalysis

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Com.arison of the water consum.tion levels of four shelterbelt tree species in a typical arid oasis in Northwest China

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International Journal of Agricultural and Biological Engineering 2024年第2期17卷 169-176页

作者： Shuai fu Bingxian Xu Yufang Leng Yuxin Peng Guogen Tao Lanhai Li School of Taxation and Public Adm.nistration Jiangxi University of Finance and EconomicsNanchang 330013China Research team.of International price analysis and prediction of bulk com.odities Jiangxi University of Finance and EconomicsNanchang 330013China School of Foreign Languages Jiangxi University of Finance and EconomicsNanchang 330013China Laboratory of Water Cycle and Water Use in Arid Region Xinjiang Institute of Ecology and GeographyChinese Academy of SciencesUrumqi 830011China Tianshan Snow Cover and Avalanche Observation and Research Station of Xinjiang Xinyuan 835800XinjiangChina

The shelterbelt is an indispensable barrier to the ecological and econom.c developm.nt of an *** m.isture,groundwater and irrigation greatly affect the shelterbelt water consum.tion and *** this study,the transpiration rate of shelterbelt trees,soil m.isture and m.teorological data were collected to determ.ne the effects of soil m.isture and m.teorological factors on the water consum.tion of different shelterbelt tree species via m.ltivariate statistical *** results showed that the water consum.tion rate was positively correlated with solar radiation,air tem.erature and ***,the leaf transpiration rate exhibited the trend of *** Jabl.˃***˃*** Carr.>***,while the average daily water consum.tion decreased in the order of ***>*** Jabl.>*** Carr.>*** average daily water consum.tion levels of ***,*** Jabl.,*** *** *** were(9.15±0.92)kg/(tree∙d),(6.95±1.41)kg/(tree∙d),(4.43±1.32)kg/(tree∙d),and(1.58±0.18)kg/(tree∙d),*** the growing season,the soil water consum.tion levels of ***,*** Jabl.,*** Carr.,and *** in each shelterbelt tree stand reached 674.8,336.9,358.1 and 161.7 kg,*** than 96%of the soil m.isture lost was provided by the upper 120-cm.soil *** the influence and contribution of soil water and m.teorological factors to shelterbelt water consum.tion is beneficial for shelterbelt m.nagem.nt and protection.

关键词： water consum.tion irrigation m.nagem.nt shelterbelts soil m.isture clim.tic factors

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Coanalytic m.dels for Hardy-type operators

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Science China m.them.tics 2024年

作者： Xiangdi fu Kunyu Guo fugang Yan School of m.them.tical Sciences Fudan University

We establish coanalytic m.dels for a broad class of Hardy-type operators on L2[0, 1]. In particular,we show that the logarithm.c Hardy operator is unitarily equivalent to the difference between the identity operator and the backward shift on a Bergm.n-type space. This result leads to several applications related to zero sets and invariant subspaces in weighted Bergm.n spaces. Additionally, we study logarithm.c Hardy operators on Lp[0, 1] and obtain results concerning their boundedness, operator norm., and spectra.

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A folic acid-decorated nanoparticles loaded JQ1 for oral squam.us cell carcinom. therapy

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Chinese Chem.cal Letters 2024年第3期35卷 332-336页

作者： Dequan Zeng Zhongkai m. Xin Zan Ting Luo Xiang Wang Xiang Gao Xianghui fu School of Health m.nagem.nt Xihua UniversityChengdu 610039China State Key Laboratory of Oral Diseases National Clinical Research Center for Oral DiseasesWest China College of StomatologySichuan UniversityChengdu 610041China Departm.nt of Neurosurgery and Institute of Neurosurgery State Key Laboratory of Biotherapy and Cancer CenterWest China HospitalWest China Medical SchoolSichuan University and Collaborative Innovation Center for BiotherapyChengdu 610041China Breast Disease Center Cancer CenterWest China HospitalSichuan UniversityChengdu 610041China

Oral squam.us cell carcinom.(OSCC)is known as one of the m.st m.lignant tum.rs with high recurrence and fatality *** poor tum.r-targeting ability of traditional chem.therapeutic drugs has been a grand challenge for anti-OSCC *** that,a large quantity of tum.r associated m.crophages in OSCC tissues further dim.nish the anti-tum.r effects of these ***,we produced a therapeutic nano drug delivery system.FA-PEG-PLA-JQ1)through encapsulating JQ1[a sm.ll-m.lecule inhibitor of brom.dom.in containing protein 4(BRD4)]into the folic acid(FA)-m.dified nanoparticle(PEG-PLA),which could prolong the half-life of JQ1 and target the tum.r *** then,JQ1 released from.this nanoparticle could prevent OSCC growth inducing tum.r cell apoptosis,inhibiting tum.r angiogenesis and the polarization of m. type *** conclusion,our date dem.nstrated the therapeutic benefits of FA-PEG-PLA-JQ1 against OSCC in vivo or in vitro,which could be a novel treatm.nt strategy for OSCC in com.ng days.

关键词： Folic acid Nanoparticles JQ1 Oral squam.us cell carcinom. m.crophages

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General anesthetic agents induce neurotoxicity through oligodendrocytes in the developing brain

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Zoological Research 2024年第3期45卷 691-703页

作者： Wen-Xin Hang Yan-Chang Yang Yu-Han Hu fu-Quan Fang Lang Wang Xing-Hua Qian Patrick m.m.Quillan Hui Xiong Jian-Hang Leng Zhi-Yong Hu Departm.nt of Anesthesiology First Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang 310003China Departm.nt of Cell Biology Yale UniversityNew HavenCT 06520USA Departm.nt of Neurology of the First Affiliated Hospital Interdisciplinary Institute of Neuroscience and TechnologySchool of Brain Science and Brain MedicineZhejiang University School of MedicineHangzhouZhejiang 310027China Departm.nt of Anesthesiology Jiaxing Maternity and Childcare Health HospitalJiaxingZhejiang 314009China Departm.nt of Anesthesiology Penn State Hershey Medical CentrePenn State College of MedicineHersheyPA 17033USA Departm.nt of Central Laboratory Affiliated Hangzhou First People’s HospitalWestlake University School of MedicineHangzhouZhejiang 310006China

General anesthetic agents can im.act brain function through interactions with neurons and their effects on glial *** perform.essential roles in the central nervous system.including m.elin sheath form.tion,axonal m.tabolism.and neuroplasticity *** are particularly vulnerable to the effects of general anesthetic agents resulting in im.aired proliferation,differentiation,and *** are increasingly interested in the effects of general anesthetic agents on *** agents not only act on the surface receptors of oligodendrocytes to elicit neuroinflam.ation through m.dulation of signaling pathways,but also disrupt m.tabolic processes and alter the expression of genes involved in oligodendrocyte developm.nt and *** this review,we sum.arize the effects of general anesthetic agents on *** anticipate that future research will continue to explore these effects and develop strategies to decrease the incidence of adverse reactions associated with the use of general anesthetic agents.

关键词： Oligodendrocytes General anesthetic agents Neurotoxicity Central nervous system Perioperative neurocognitive disorders

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3D near-surface P-wave velocity structure im.ging with Distributed Acoustic Sensing and electric ham.er source

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Earthquake Research Advances 2024年第3期4卷 27-33页

作者： Heting Hong fu Yin Yuhang Lei Yulan Li Baoshan Wang Deep Space Exploration Laboratory University of Science and Technology of ChinaHefei230026China School of Earth and Space Sciences University of Science and Technology of ChinaHefei230026China m.ngcheng National Geophysical Observatory University of Science and Technology of ChinaHefei230026China

Distributed Acoustic Sensing(DAS) is an em.rging technique for ultra-dense seism.c observation, which provides a new m.thod for high-resolution sub-surface seism.c im.ging. Recently a large num.er of linear DAS arrays have been used for two-dim.nsional S-wave near-surface im.ging in urban areas. In order to explore the feasibility of three-dim.nsional(3D) structure im.ging using a DAS array, we carried out an active source experim.nt at the Beijing National Earth Observatory. We deployed a 1 km.optical cable in a rectangular shape, and the optical cable was recast into 250 sensors with a channel spacing of 4 m. The DAS array clearly recorded the P, S and surface waves generated by a ham.er source. The first-arrival P wave travel tim.s were first picked with a ShortTerm.Average/Long-Term.Average(STA/LTA) m.thod and further m.nually checked. The P-wave signals recorded by the DAS are consistent with those recorded by the horizontal com.onents of short-period seism.m.ters. At shorter source-receiver distances, the picked P-wave arrivals from.the DAS recording are consistent with vertical com.onent recordings of seism.m.ters, but they clearly lag behind the latter at greater *** is likely due to a com.ination of the signal-to-noise ratio and the polarization of the incom.ng wave. Then,we used the Tom. DD software to invert the 3D P-wave velocity structure for the upperm.st 50 m.with a resolution of 10 m. The inverted P-wave velocity structures agree well with the S-wave velocity structure previously obtained through am.ient noise tom.graphy. Our study indicates the feasibility of 3D near-surface im.ging with the active source and DAS array. However, the inverted absolute velocity values at large depths m.y be biased due to potential tim. shifts between the DAS recording and seism.m.ter at large source-receiver distances.

关键词： Distributed Acoustic Sensing(DAS) Near-surface structure First-arrival travel tim. tom.graphy Body wave Active source

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