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Efficacy of stenting for unprotected left main coronary artery disease in 297 patients

Chinese Medical Journal 2006年第7期119卷 544-550页

作者： HAN Ya-ling WANG Shou-li jin quan-min liu Hai-wei MA Ying-yan WANG Zhu-lu WANG dong-mei luAN Bo WANG geng Department of Cardiology Shenyang General Hospital of PLAShenyang 110016 China

Background Angioplasty in the unprotected left main coronary artery （LMCA） has been controversial. This study aims to evaluate the safety and clinical effectiveness of stenting, including bare metal stent and drug eluting stent （DES）, for treatment of unprotected LMCA disease. Methods Between September 1997 and December 2005, a total of 297 consecutive patients underwent percutanous coronary intervention （PCI） on LMCA lesions in our hospital. Their in-hospital data and clinical follow-up outcomes were analyzed and those in pre-DES ＂＇era＂（group I, from September 1997 to December 2002） were compared with those in DES ＂era＂（group Ⅱ, from January 2003 to December 2004. Patients in 2005 for the time of follow-up less than one year were not included in this group）. Results Altogether 368 coronary stents were successfully deployed in 295 patients. Stents failed to be implanted after balloon predilation in two patients, who received coronary artery bypass graft （CABG） successfully. Bifurcation techniques for distal LMCA executed in 206 patients （69.4%, 2061297）, included crossover stenting in 156 （75.7%）, T stenting in 4 （1.9%）, provisional T stenting in 28 （13.6%）, kissing stenting in 5 （2.4%） and stent crushing in 13 （6.3%） patients. During their hospital stay, 5 （1.7%） patients died after PCI procedure, of which 4 died from cardiac origin and one of renal failure. The total in-hospital major adverse cardiac events （MACE） were 2.0% （6/297）. In the follow-up period, 19 patients （6.5%） died [15 （5.1%） of cardiac death and 4 of non-fatal myocardial infarction （MI）]. Besides, 2 （0.7%） developed subacute thrombosis （SAT） and 16 （5.4%） performed target lesion revascularization （TLR）. The total follow-up MACE was 14.5% （431297）. further analysis also showed that, compared with patients in group I, those in group II apparently had more multi-vessel involvement （14.7% vs 81.9%, P〈0.001）, and more bifurcation lesions （32.4% vs 72.2%, P〈0.001）. After PCI, in-hospital MACE of g

关键词： coronary heart disease left main coronary artery percutanous coronary intervention stenting

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计入关节摩擦的空间桁架结构动力学建模及共振分析

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振动工程学报 2021年第4期34卷 663-670页

作者：刘福寿徐文婷金栋平刘向东路平立南京林业大学土木工程学院江苏南京210037 南京航空航天大学机械结构力学及控制国家重点实验室江苏南京210016 北京理工大学自动化学院北京100081

关节非线性对大型可展开空间桁架结构整体动力学特性有着重要影响。将关节模拟为具有六个方向刚度且其中任意方向可含有非线性特性的弹簧系统,研究了空间桁架结构非线性动力学建模与共振分析方法。采用双线性滞回模型模拟关节的摩擦特性... 详细信息

关节非线性对大型可展开空间桁架结构整体动力学特性有着重要影响。将关节模拟为具有六个方向刚度且其中任意方向可含有非线性特性的弹簧系统,研究了空间桁架结构非线性动力学建模与共振分析方法。采用双线性滞回模型模拟关节的摩擦特性,基于描述函数法得到了关节等效刚度和等效阻尼的解析表达式。在对两端含非线性关节的桁架构件进行动力学缩聚的基础上,建立了桁架结构在频域下的整体缩聚动力学模型,并采用Newton⁃Raphson迭代方法进行频域响应求解。通过数值算例将本文方法的计算结果与有限元分析结果进行比较,验证了本文方法的准确性和高效性。

关键词：结构振动空间桁架结构非线性关节摩擦滑移双线性滞回模型

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Caudate lobectomy by the third porta hepatis anatomical method: a study of 16 cases

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Hepatobiliary & Pancreatic Diseases International 2006年第3期5卷 387-390页

作者： Huai-quan Zuo, lu-Nan Yan, yong Zeng, Jia-Ying Yang, Hong-Zhi luo, Jiang-Wen liu, li-Xin Zhou and Qiang jin Department of general Surgery, West China Hospital, Sichuan University, Chengdu 610041, China Department of general Surgery West China Hospital Sichuan University Chengdu 610041 China. Zuohuaiquan@***

BACKGROUND: The treatment for primary tumor in the caudate lobe of the liver is difficult because of its unique anatomical location. This study was undertaken to improve operative techniques and results by a new anatomical method of caudate lobectomy. METHODS: Clinical data of 16 patients who had had caudate lobectomy for the liver from January 1996 to November 2004 were retrospectively analyzed. The third porta hepatis anatomical method was performed in all 16 patients. Operative time, intraoperative blood loss, postoperative complications were recorded. The 1-, 3-, and 5-year survival rates of 13 patients with caudate lobe carcinoma were followed up. Anatomical status, operative routes, operative procedures, liver blood supply were evaluated. RESULTS: The operation was successful in the 16 patients. The operative time was 255±70 minutes and blood loss 740±402 ml. None of the patients died from massive bleeding during the operation, nor did complications such as biliary fistula and liver failure occurred. In 13 patients with malignant tumor, 7 died from recurrence and metastasis of the tumor and the other 6 are still alive at the end of follow-up. One patient has survived for 6 years. The 1-, 3-, and 5-year survival rates in the 13 patients were 83.9%, 58.7% and 39.2%, respectively. CONCluSION: Caudate lobectomy by the third porta hepatis anatomical method can improve operative effect and increase the resection probability for solitary tumor in the caudate lobe.

关键词： caudate lobectomy the third porta hepatis anatomy titanium clip

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Nucleolar stress regulates stromal-epithelial transition via NPM1 during decidualization

Nucleolar stress regulates stromal-epithelial transition via...

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第十六届中国实验动物科学年会

作者： Yu-xiang liang Wei Hu Zhi-yong jin Hong-lu Diao li liu Yan Yang Tao fu Zeng-Ming Yang Shanxi Key Laboratory of Birth Defect and Cell Regeneration Shanxi Medical University College of Veterinary Medicine South China Agricultural University College of life Science and Resources and Environment Yichun University Reproductive Medicine Center Renmin HospitalHubei University of Medicine

Embryo implantation and decidualization are crucial steps during early *** recently showed that nucleolar stress is involved in embryo *** study was to explore whether nucleolar stress participates in mouse and human *** data demonstrated that a low-dose of actinomycin D(ActD) could induce nucleolar stress in stroma *** stress promotes the stromal-epithelial transition during mouse in vitro decidualization through nucleophosminl(NPM1).Under nucleolar stress,Wnt family member 4(Wnt4),a decidualization marker,is significantly increased,but decidua/trophoblast prolactin-related protein(Dtprp/Prl8a2) expression remains *** translational significance,we also examined effects of nucleolar stress on human *** stress stimulated by a low-dose of ActD enhances human stromal-epithelial transition during human decidualization,but has no effects on the expression of insulin-like growth factor binding protein 1(IGFBP1).Our study indicates that nucleolar stress may promote only the mesenchymal-epithelial transition(MET),but not for all of the molecular changes during decidualization.

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砂-黏土混合物高压压实性能试验研究

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岩土力学 2019年第9期40卷 3502-3514页

作者：李玲刘金泉刘造保刘桃根王伟邵建富南昌工程学院水利与生态工程学院江西南昌330099 法国里尔大学里尔力学实验室法国里尔中国科学院海西研究院泉州装备制造研究所福建泉州362201 河海大学岩土力学与堤坝工程教育部重点实验室江苏南京210098

利用自行设计高压固结仪对5种不同含砂率的饱和砂-黏土混合物开展一系列高压压缩试验,研究砂-黏土混合物压缩性和渗透性演化规律及其对矿物组分的依赖性。试验结果表明,饱和砂-黏土混合物的孔隙比-压力(e-lgP)曲线随着含砂率增高呈现出... 详细信息

利用自行设计高压固结仪对5种不同含砂率的饱和砂-黏土混合物开展一系列高压压缩试验,研究砂-黏土混合物压缩性和渗透性演化规律及其对矿物组分的依赖性。试验结果表明,饱和砂-黏土混合物的孔隙比-压力(e-lgP)曲线随着含砂率增高呈现出指数函数模式向双曲线函数模式转化,而e-P曲线在压力高于8.1 MPa则呈线性变化,其斜率依赖于含砂率。最优含砂率随固结压力的增大而逐渐从75%移向30%。不同含砂率的砂-黏土混合物的孔隙率、固结压力和含砂率存在统一的幂函数关系。渗透系数与含砂率有关,渗透系数与孔隙率符合指数函数关系。从砂-黏土混合物骨架结构和孔隙类型的角度出发,从本质上分析含砂率、固结压力对混合物压缩性和渗透性的作用规律。结合SEM微细观结构观测结果,验证砂-黏土混合物骨架结构与含砂率之间的相关性。

关键词：砂-黏土混合材料压缩性含砂率孔隙结构渗透性

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A transcriptional cascade involving BBX22 and HY5 finely regulates both plant height and fruit pigmentation in citrus

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Journal of Integrative Plant Biology 2024年第8期66卷 1752-1768页

作者： Jialing fu li liao Jiajing jin Zhihao lu Juan Sun lizhi Song Yue Huang Shengjun liu Ding Huang Yuantao Xu Jiaxian He Bin Hu Yiqun Zhu Fangfang Wu Xia Wang Xiuxin Deng Qiang Xu National Key Laboratory for Germplasm Innovation and Utilization of Horticultural Crops College of Horticulture and Forestry SciencesHuazhong Agricultural UniversityWuhan 430070P.R.China Hubei Hongshan Laboratory Wuhan 430070P.R.China Science and Technology Innovation Research Center of Majia Pomelo Shangrao 334000China

Dwarfing is a pivotal agronomic trait affecting both yield and *** species exhibit substantial variation in plant height,among which internode length is a core ***,the molecular mechanism governing internode elongation remains ***,we unveiled that the transcriptional cascade consisting of B-BOX DOMAIN PROTEIN 22(BBX22)and ELONGATED HYPOCOTYL 5(HY5)finely tunes plant height and internode elongation in ***-of-function mutations of BBX22 in an early-flowering citrus(Citrus hindsii“SJG”)promoted internode elongation and reduced pigment accumulation,whereas ectopic expression of BBX22 in SJG,sweet orange(***),pomelo(***)or heterologous expression of BBX22 in tomato(Solanum lycopersicum)significantly decreased internode ***,exogenous application of gibberellin A3(GA3)rescued the shortened internode and dwarf phenotype caused by *** experiments revealed that BBX22 played a dual role in regulation internode elongation and pigmentation in *** the one hand,it directly bound to and activated the expression of HY5,GA metabolism gene(GA2 OXIDASE 8,GA2ox8),carotenoid biosynthesis gene(PHYTOENE SYNTHASE 1,PSY1)and anthocyanin regulatory gene(Ruby1,a MYB DOMAIN PROTEIN).On the other hand,it acted as a cofactor of HY5,enhancing the ability of HY5 to regulate target genes ***,our results reveal the critical role of the transcriptional cascade consisting of BBX22 and HY5 in controlling internode elongation and pigment accumulation in *** the crosstalk regulatory mechanism between internode elongation and fruit pigmentation provides key genes for breeding of novel types with both dwarf and health-beneficial fortification in citrus.

关键词： anthocyanins BBX22 carotenoids citrus HY5 internode elongation plant height

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Frontiers in high entropy alloys and high entropy functional materials

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Rare Metals 2024年第10期43卷 4639-4776页

作者： Wen-Tao Zhang xue-Qian Wang Feng-Qi Zhang Xiao-Ya Cui Bing-Bing Fan Jia-Ming Guo Zhi-Min Guo Rui Huang Wen Huang Xu-Bo li Meng-Ru li Yan Ma Zhi-Hua Shen yong-Gang Sun De-Zhuang Wang Fei-Yang Wang li-Qiang Wang Nan Wang Tian-li Wang Wei Wang Xiao-Yang Wang Yi-Han Wang fu-Jie Yu Yu-Zhen Yin ling-Kun Zhang Yi Zhang Jian-Yang Zhang Qi Zhao Yu-Ping Zhao Xin-dong Zhu Yasir Sohail Ya-Nan Chen Tao Feng Qi-Long Gao Hai-Yan He yong-Jiang Huang Zeng-Bao Jiao Hua Ji Yao Jiang Qiang li Xiao-Ming li Wei-Bing liao Huai-Jun lin Hui liu Qi liu Qing-Feng liu Wei-Di liu Xiong-Jun liu Yang lu Yi-Ping lu Wen Ma xue-Fei Miao Jie Pan Qing Wang Hong-Hui Wu Yuan Wu Tao Yang Wei-Ming Yang Qian Yu jin-Yu Zhang Zhi-Gang Chen liang Mao Yang Ren Bao-Long Shen Xun-li Wang Zhe Jia He Zhu Zhen-Duo Wu Si Lan School of Materials Science and Engineering Nanjing University of Science and TechnologyNanjing 210094China Jiangsu Key Laboratory for Advanced Metallic Materials School of Materials Science and EngineeringSoutheast UniversityNanjing 211189China Department of Physics City University of Hong KongHongKong 999077China School of Materials Science and Engineering Tianjin UniversityTianjin 300072China School of Physics and Microelectronics Zhengzhou UniversityZhengzhou 450001China Department of Mechanical Engineering Research Institute for Advanced ManufacturingThe Hong Kong Polytechnic UniversityHong Kong 100872China Center of Electron Microscopy and State Key Laboratory of Silicon Materials School of Materials Science and EngineeringZhejiang UniversityHangzhou 310027China Key Laboratory of Solidification Control and Digital Preparation Technology(liaoning Province) School of Materials Science and EngineeringDalian University of TechnologyDalian 116024China Institute of Advanced Wear&Corrosion Resistance and functional Materials Jinan UniversityGuangzhou 510632China School of Mechanics and Civil Engineering China University of Mining and TechnologyXuzhou 221116China School of Physical Sciences Great Bay UniversityDongguan 523000China School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001China State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical EngineeringNanjing Tech UniversityNanjing 211816China Beijing Advanced Innovation Center for Materials genome Engineering Research Institute for Carbon NeutralityUniversity of Science and Technology BeijingBeijing 100083China Department of Mechanical Engineering The University of Hong KongHong Kong 999077China School of Computing Macquarie UniversitySydney 2113Australia Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Physics and Optoelectronic EngineeringShenzhen UniversityShenzhen 518060China State Key Laborato

Owing to their exceptional properties,high-entropy alloys(HEAs)and high-entropy materials have emerged as promising research areas and shown diverse ***,the recent advances in the field are comprehensively reviewed,organized into five *** first section introduces the background of HEAs,covering their definition,significance,application prospects,basic properties,design principles,and *** subsequent section focuses on cutting-edge high-entropy structural materials,highlighting developments such as nanostructured alloys,grain boundary engineering,eutectic systems,cryogenic alloys,thin films,micro-nano-lattice structures,additive manufacturing,high entropy metallic glasses,nano-precipitate strengthened alloys,composition modulation,alloy fibers,and refractory *** the following section,the emphasis shifts to functional materials,exploring HEAs as catalysts,magneto-caloric materials,corrosion-resistant alloys,radiation-resistant alloys,hydrogen storage systems,and materials for ***,the review encompasses functional high-entropy materials outside the realm of alloys,including thermoelectric,quantum dots,nanooxide catalysts,energy storage materials,negative thermal expansion ceramics,and high-entropy wave absorption *** paper concludes with an outlook,discussing future directions and potential growth areas in the *** this comprehensive review,researchers,engineers,and scientists may gain valuable insights into the recent progress and opportunities for further exploration in the exciting domains of high-entropy alloys and functional materials.

关键词： High entropy alloys Cutting-edge structural materials Cutting-edgefunctional materials

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同源四倍体水稻亚种间杂种胚囊的结构及受精特点

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作物学报 2005年第9期31卷 1150-1156,i0002-i0004页

作者：肖波刘向东卢永根李金泉赵杏娟华南农业大学广东省植物分子育种重点实验室广东广州510642

利用激光扫描共聚焦显微术对11份同源四倍体水稻亚种间杂种的胚囊结构和双受精特点进行研究，结果表明，所有四倍体杂种均存在一定频率的败育胚囊，败育频率因组合而异，最高的败育率为23．8％，最低为5．5％，平均14．3％。败育胚囊主... 详细信息

利用激光扫描共聚焦显微术对11份同源四倍体水稻亚种间杂种的胚囊结构和双受精特点进行研究，结果表明，所有四倍体杂种均存在一定频率的败育胚囊，败育频率因组合而异，最高的败育率为23．8％，最低为5．5％，平均14．3％。败育胚囊主要有胚囊退化、异常小胚囊、无卵器、无雌性生殖单位和极核位置异常等5种类型。杂种在双受精过程中也存在一定频率的异常，包括胚囊结构正常但未能受精和受精停滞等，其中未能受精的频率为3．5％～11．9％。平均7．9％，受精停滞的频率为1．1％～6．2％，平均3．7％。另外，还存在低频率（平均4．7％）的胚乳发育受阻。认为部分胚囊败育和受精异常（包括未能受精和受精停滞）是导致同源四倍体水稻亚种间杂种结实率降低的主要原因。

关键词：同源四倍体水稻亚种间杂种胚囊受精激光扫描共聚焦显微术

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The future of remote ECG monitoring systems

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Journal of Geriatric Cardiology 2016年第6期13卷 528-530页

作者： Shu-li GUO li-Na HAN Hong-Wei liu quan-jin SI De-Feng KONG fu-Su GUO School of Automation Beijing Institute of Technology Beijing China Department of Cardiology lnternal Medicine Nanlou Branch of Chinese PLA General Hospital Beijing China

Remote ECG monitoring systems are becoming commonplace medical devices for remote heart monitoring. In recent years, remote ECG monitoring systems have been applied in the monitoring of various kinds of heart diseases, and the quality of the transmission and re- ception of the ECG signals during remote process kept advancing. However, there remains accompanying challenges. This report focuses on the three components of the remote ECG monitoring system： patient （the end user）, the doctor workstation, and the remote server, reviewing and evaluating the imminent challenges on the wearable systems, packet loss in remote transmission, portable ECG monitoring system, pa- tient ECG data collection system, and ECG signals transmission including real-time processing ST segment, R wave, RR interval and QRS wave, etc. This paper tries to clarify the future developmental strategies of the ECG remote monitoring, which can be helpful in guiding the research and development of remote ECG monitoring.

关键词： Cardiovascular system ECG Remote monitoring

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luPO_4晶体中F心和F^+心的光谱性质模拟计算

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光子学报 2018年第7期47卷 207-213页

作者：李金刘廷禹付明雪鲁晓晓上海理工大学理学院上海200093 上海市现代光学重点实验室上海200093

基于密度泛函理论下的广义梯度近似结合平面波赝势方法计算得到luPO_4晶体的缺陷形成能,对带电缺陷与其镜像之间周期性库伦作用进行修正,得到比较精确的不同带电态的氧空位缺陷形成能,并利用杂化泛函方法修正带隙和带边.考虑电子声子耦... 详细信息

基于密度泛函理论下的广义梯度近似结合平面波赝势方法计算得到luPO_4晶体的缺陷形成能,对带电缺陷与其镜像之间周期性库伦作用进行修正,得到比较精确的不同带电态的氧空位缺陷形成能,并利用杂化泛函方法修正带隙和带边.考虑电子声子耦合作用结合缺陷形成能构建光谱.对比luPO_4∶Nd的实验结果与计算结果,发现F心的吸收峰与Nd^(3+)的5d—4f发射峰重叠(位于189nm),表明luPO_4∶Nd中光产额较低的原因与F心的存在有密切关系.

关键词：第一性原理 luPO4晶体 F心电子声子耦合 FNV修正

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