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Fe_3O_4 Nanoparticles Decorated Multi-walled Carbon Nanotubes and Their Sorption Properties

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Chemical Research in Chinese Universities 2009年第6期25卷 936-940页

作者： DONG Cun-ku LI xin ZHANG Yan QI Jing-yao yuan Yun-fang Department of Chemistry Harbin Institute of Technology Harbin 150090 P. R. China Department of Chemistry and Chemical Engineering Binzhou University Binzhou 256600 P. R. China School of Municipal and Environmental Engineering Harbin Institute of Technology Harbin 150090 P. R. China

This paper reports a simple and efficient chemical method to decorate multi-walled carbon nano- tubes（MWCNTs） with iron oxide nanoparticles. The TEM, FTIR, Raman and UV analysis demonstrate that iron oxide nanoparticles were well deposited on the outer walls of MWCNTs. The size of the nanoparticles ranges from 30 to 50 nm. The sorption property of MWCNTs/Fe3O4 composites for the removal of 2,4-dichlorophenol（2,4-DCP） and Cu2＋ ions from aqueous solution was explored. The results present that MWCNTs decorated with Fe3O4 possessed higher sorption capability for removing 2,4-DCP and Cu2＋ ions, which favour the highly potential applications for pollutants removal from water.

关键词： Multi-walled nanotube Decoration Iron oxide 2, 4-Dichlorophenol Copper（Ⅱ）

Selective Ferroptosis Inhibitor Liproxstatin-1 Attenuates Neurological Deficits and Neuroinflammation After Subarachnoid Hemorrhage

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Neuroscience Bulletin 2021年第4期37卷 535-549页

作者： Yang Cao Yin Li Chao He Feng Yan Jian-Ru Li Hang-Zhe Xu Jian-Feng Zhuang Hang Zhou Yu-Cong Peng Xiong-Jie Fu Xiao-Yang Lu yuan Yao Yu-Yu Wei Yun Tong Yi-Fu Zhou Lin Wang Department of Neurosurgery The Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou310009China

Ferroptosis is a form of iron-dependent regulated cell death.Evidence of its existence and the effects of its inhibitors on subarachnoid hemorrhage(SAH)is still lacking.In the present study,we found that liproxstatin-1 protected HT22 cells against hemin-induced injury by protecting mitochondrial Functions and ameliorating lipid peroxidation.In in vivo experiments,we demonstrated the presence of characteristic shrunken mitochondria in ipsilateral cortical neurons after SAH.Moreover,liproxstatin-1 attenuated the neurological deficits and brain edema,reduced neuronal cell death,and restored the redox equilibrium after SAH.The inhibition of ferroptosis by liproxstatin-1 was associated with the preservation of glutathione peroxidase 4 and the downregulation of acylCoA synthetase long-chain family member 4 as well as cyclooxygenase 2.In addition,liproxstatin-1 decreased the activation of microglia and the release of IL-6,IL-1 b,and TNF-a.These data enhance our understanding of cell death after SAH and shed light on Future preclinical studies.

关键词： Subarachnoid hemorrhage Ferroptosis Inflammation Liproxstatin-1

Study regarding typical liquefaction damage during the 2021 Maduo M_(s)7.4 earthquake in China

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Earthquake Engineering and Engineering Vibration 2023年第4期22卷 895-908页

作者： yuan Jinyuan Wang Yunlong Ma Jiajun Zhan Beilei yuan Xiaoming Wang Lanmin Wu Xiaoyang School of Civil Engineering Heilongjiang University of Science and TechnologyHarbin 150027China Key Laboratory of Earthquake Engineering and Engineering Vibration Institute of Engineering MechanicsChina Earthquake AdministrationKey Laboratory of Earthquake Disaster MitigationMinistry of Emergency ManagementHarbin 150080China Qinghai Earthquake Agency China Earthquake AdministrationXining 810001China Lanzhou Institute of Seismology China Earthquake AdministrationLanzhou 730000China

The most important method of understanding liquefaction-induced engineering failures comes from the investigation and analysis of earthquake damage.In May 2021,the Maduo M_(s)7.4 earthquake occurred on the Tibetan Plateau of China.The most representative engineering disaster caused by this earthquake was bridge damage on liquefied sites.In this study,the mutual relationships between the anti-liquefaction pre-design situation,the ground motion intensity,the site liquefaction severity,and the bridge damage state for this earthquake were systematically analyzed for typical bridge damage on the liquefied sites.Using field survey data and the current Chinese industry code,simulations of the liquefaction scenarios at typical bridge sites were performed for the pre-design seismic ground motion before the earthquake and the seismic ground motion during the earthquake.By combining these results with post-earthquake investigation results,the reason for the serious bridge damage resulting from this earthquake is revealed,and the necessary conditions for avoiding serious seismic damage to bridges built in liquefiable sites is presented.

关键词： seismic liquefaction Maduo M_(s)7.4 earthquake bridge damage seismic code

氧化石墨烯负载铁锰复合材料对镉砷污染土壤的钝化修复

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环境科学 2024年第2期45卷 1107-1117页

作者：袁婧吴骥子连斌袁峰孙淇田欣赵科理浙江农林大学环境与资源学院杭州311300 浙江农林大学浙江省土壤污染生物修复重点实验室杭州311300

为修复受到镉砷复合污染的农田土壤,将铁锰氧化物负载于氧化石墨烯表面,制备得到了新型氧化石墨烯负载铁锰复合材料.在此基础上开展了为期60 d土壤培养试验,通过对pH、DOC含量、土壤有效态Cd和As含量动态变化,以及土壤Cd和As形态的测定... 详细信息

为修复受到镉砷复合污染的农田土壤,将铁锰氧化物负载于氧化石墨烯表面,制备得到了新型氧化石墨烯负载铁锰复合材料.在此基础上开展了为期60 d土壤培养试验,通过对pH、DOC含量、土壤有效态Cd和As含量动态变化,以及土壤Cd和As形态的测定,探究了氧化石墨烯(GO)和氧化石墨烯负载铁锰复合材料(GO-FM)在不同添加比例下(0.1%、0.2%和0.3%),对上虞和佛山两种理化性质和污染程度不同的土壤中Cd和As的钝化效果,并阐明其相应修复机制.结果表明,与空白对照相比,GO-FM提高了酸性上虞土的pH,但使佛山土pH降低.培养结束后,GO和GO-FM处理均增加了土壤DOC含量.GO-FM使佛山土可溶态Cd含量降低了5.08%~19.19%,有效态Cd含量降低了36.57%~42.8%,其主要钝化机制是静电吸附、络合和羟基化金属离子的形成.而酸性上虞土受静电斥力的影响使得GO-FM对Cd的钝化效果低于佛山土,但随着材料添加量的增加,GO-FM使氧化石墨烯增加土壤Cd有效性的趋势得到了抑制,添加0.2%和0.3%的GO-FM使上虞土有效态Cd含量降低了6.45%~13.56%.同时,复合材料通过锰氧化物对As的氧化作用以及As与铁氧化物表面羟基形成内表面螯合物的钝化机制,促使上虞土和佛山土的有效态As含量分别降低了4.34%~9.15%和0.87%~5.71%.总之,在佛山土中GO-FM对Cd的钝化效果优于上虞土,在上虞土中GO-FM对As的钝化效果优于佛山土.研究结果可为不同类型土壤镉砷复合污染防治提供理论依据和参考.

关键词：镉砷复合污染氧化石墨烯(GO) 铁锰钝化土壤修复

Germinated brown rice relieves hyperlipidemia by alleviating gut microbiota dysbiosis

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Journal of Integrative Agriculture 2023年第3期22卷 945-957页

作者： REN Chuan-ying ZHANG Shan HONG Bin GUAN Li-jun HUANG Wen-gong FENG Jun-ran SHA Di-xin yuan Di LI Bo JI Ni-na LIU Wei LU Shu-wen Food Processing Research Institute Heilongjiang Academy of Agricultural SciencesHarbin 150086P.R.China Heilongjiang Province Key Laboratory of Food Processing Harbin 150086P.R.China Safety and Quality Institute of Agricultural Products Heilongjiang Academy of Agricultural SciencesHarbin 150086P.R.China Soybean Research Institute Heilongjiang Academy of Agricultural SciencesHarbin 150086P.R.China The Second Affiliated Hospital Harbin Medical UniversityHarbin 150086P.R.China

Hyperlipidemia is a frequent metabolic disorder that is closely associated with diet. It is believed that brown rice, containing the outer bran layer and germ, is beneficial for the remission of hyperlipidemia. This study established a rat model of hyperlipidemia by feeding a high-fat diet. The hypolipidemic potential of germinated brown rice(Gbrown) and germinated black rice(a germinated black-pigmented brown rice, Gblack) were explored in the model rats, mainly in the aspects of blood lipids, lipases, apolipoproteins, and inflammation. The gut microbiota in hyperlipidemic rats receiving diverse dietary interventions was determined by 16S rDNA sequencing. The results showed that the intervention of Gbrown/Gblack alleviated the hyperlipidemia in rats, evidenced by decreased TC, TG, LDL-C, and apolipoprotein B, and increased HDL-C, HL, LPL, LCAT, and apolipoprotein A1. Gbrown/Gblack also weakened the inflammation in hyperlipidemia rats, evidenced by decreased TNF-α, IL-6, and ET-1. In addition, 16S rDNA sequencing revealed that the diet of Gbrown/Gblack elevated the abundance and diversity of gut microbiota in hyperlipidemia rats. At the phylum level, Gbrown/Gblack decreased Firmicutes, increased Bacteroidetes, and decreased the F/B ratio in hyperlipidemia rats. At the genus level, Gbrown/Gblack decreased Streptococcus and increased Ruminococcus and Allobaculum in hyperlipidemia rats. Some differential microbial genera relating to lipid metabolism were also determined, such as the Lachnospira and Ruminococcus in the Gblack group, and the Phascolarctobacterium, Dorea, Turicibacter, and Escherichia-Shigella in the Gbrown group. Notably, the beneficial effect of Gblack was stronger than Gbrown. To sum up, the dietary interventions of Gbrown/Gblack contributed to the remission of hyperlipidemia by alleviating the dysbiosis of gut microbiota.

关键词： hyperlipidemia germination brown rice black rice gut microbiota

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PAMM不影响人脂肪干细胞的成脂分化能力

生物化学与生物物理进展 2022年第7期49卷 1305-1317页

作者：张明萌王颖梁杰吴洪福史玉仓吴志远饶敏腊彭健愉蒋智文刘新光孙雪荣广东医科大学广东省医学分子诊断重点实验室衰老研究所东莞523808 青岛市市立医院集团输血医学科青岛266011 广东医科大学第二临床医学院东莞523808 广东医科大学附属医院整形外科湛江524001 广东医科大学干细胞与再生组织工程重点实验室东莞523808 广东医科大学生物化学与分子生物学研究所湛江524023

目的PAMM(peroxiredoxin-like 2 activated in M-CSF stimulated monocytes)是近年来发现的一种在脂肪组织中高表达的分泌因子,但其生物学功能尚不完全清楚。为了给PAMM功能研究提供新线索,本文探讨了PAMM在白色脂肪生成中的可能作用及P... 详细信息

目的PAMM(peroxiredoxin-like 2 activated in M-CSF stimulated monocytes)是近年来发现的一种在脂肪组织中高表达的分泌因子,但其生物学功能尚不完全清楚。为了给PAMM功能研究提供新线索,本文探讨了PAMM在白色脂肪生成中的可能作用及PAMM调节的下游基因。方法利用成脂分化液或“成脂分化液+IL-1α”建立人脂肪干细胞(adipose-derived stem cells,ADSCs)的成脂分化和成脂抑制模型。用si RNA干扰和过表达质粒转染的方法抑制或上调PAMM表达水平。采用基因芯片、m RNA测序及定量RT-PCR检测基因的m RNA表达水平,采用蛋白质印迹法评价蛋白质表达水平,用油红O染色检测脂滴沉积。结果随着ADSCs向白色脂肪分化,PAMM表达水平明显上升,而随着成脂抑制,PAMM表达明显下降。在ADSCs中沉默或过表达PAMM后,再进行成脂分化。结果发现,上调或下调PAMM对脂滴形成及成脂相关基因的表达均无明显影响。类似地,在高度分化的脂肪细胞中敲低PAMM表达,对细胞形态及脂滴含量亦无明显影响。本文进一步利用si RNA干扰、m RNA测序及q RT-PCR,筛选和验证了一批受PAMM调节的下游基因及功能性基因集,包括SULF1、A2M基因及调节P53稳定性的基因集等。结论PAMM可作为白色成脂分化的标志基因,但其自身对白色脂肪细胞生成无明显影响,本研究筛选出来的PAMM下游基因及基因集,可为进一步研究PAMM的功能提供新线索。

关键词： PAMM 脂肪细胞成脂分化干细胞脂肪因子

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高速线BOPP专用料的开发

当代化工 2005年第3期34卷 193-195,205页

作者：崔芙蓉郭奇许普刘新元抚顺乙烯化工有限公司辽宁抚顺113109

介绍了抚顺乙烯化工有限公司开发生产的新一代高速线BOPP专用料T38FE。采用差示扫描量热法、凝胶渗透色谱议、偏光显微镜等分析手段对T38FE进行了结构与性能研究,表明产品适合于线速350m/min以上的双向拉伸薄膜生产线。

关键词：聚丙烯 BOPP 结构

The 10th China-Japan-ROK Cultural Ministers＇ Meeting and the Culture City of East Asia Forum in Harbin

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China & The World Cultural Exchange 2018年第9期84卷 39-39页

作者： xin yuan

HPLC法测定没食子酸乙酯在大鼠体内组织分布

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化学工程师 2019年第1期33卷 27-29,26页

作者：夏文雯张强范梦格丁昕瑶李馥源王巍辽宁中医药大学药学院辽宁大连116600

建立高效液相色谱法测定大鼠组织样品中没食子酸乙酯的含量,研究其在大鼠体内的分布特征。在灌胃给药后10min、30min、2h,解剖取心、肝、脾、肺、肾、胃、小肠组织,采用高效液相色谱法测定各组织中没食子酸乙酯的浓度。结果表明,没食子... 详细信息

建立高效液相色谱法测定大鼠组织样品中没食子酸乙酯的含量,研究其在大鼠体内的分布特征。在灌胃给药后10min、30min、2h,解剖取心、肝、脾、肺、肾、胃、小肠组织,采用高效液相色谱法测定各组织中没食子酸乙酯的浓度。结果表明,没食子酸乙酯在大鼠体内分布广泛,以肝脏中分布最多,其次为肺、脾、心,在胃中分布最低,给药2h后肾脏中浓度显著增加。本研究方法简便、灵敏、准确,可用于大鼠组织中没食子酸乙酯含量的测定。

关键词：没食子酸乙酯组织分布 HPLC