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Building Simulation 2022年第5期15卷 845-858页

作者： fredrik domhagen Paula Wahlgren Carl-Eric Hagentoft Department for Architecture and Civil Engineering Division of Building TechnologyChalmers University of TechnologySE-41296GothenburgSweden

Some Swedish school buildings built in the 1960s and 1970s experience indoor air quality problems,where the contaminants are suspected to come from the crawl space underneath the *** poor indoor air quality causes discomfort among pupils and *** an exhaust fan to maintain a negative pressure difference in the crawl space relative to indoors or increasing the ventilation in the classroom are two examples of common measures taken to improve the indoor air ***,these measures are not always effective,and sometimes the school building has to be *** relation between pressure distribution,contaminant concentration in the classroom,outdoor temperature,wind,mechanical ventilation,and air leakage distribution is complex.A better understanding of these relations is crucial for making decisions on the most efficient measure to improve the indoor air *** this paper,a model for contaminant infiltration from the crawl space is used together with the Monte Carlo method to study these *** are performed for several cases where different building shapes,building orientations,shielding conditions,and geographical locations are *** show,for example,that for a building with an imbalanced ventilation system,air is leaking from the crawl space to the classroom for the majority of cases and that concentration levels in the classroom are usually the highest during mild and calm days.

关键词： airtightness air permeability Monte Carlo method infiltration model crawl space indoor air quality

Elasto-inertial focusing and particle migration in high aspect ratio microchannels for highthroughput separation

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Microsystems & Nanoengineering 2024年第3期10卷 381-394页

作者： Selim Tanriverdi Javier Cruz Shahriar Habibi Kasra Amini Martim Costa fredrik Lundell Gustaf Mårtensson Luca Brandt Outi Tammisola Aman Russom Division of Nanobiotechnology Department of Protein ScienceScience for Life LaboratoryKTH Royal Institute of TechnologySolna 17165Sweden Division of Microsystems Technology Department of Materials Science and EngineeringUppsala UniversityUppsala 75237Sweden FLOW and SeRC(Swedish e-Science Research Centre) Department of Engineering MechanicsRoyal Institute of TechnologyStockholm SE 10044Sweden FLOW and Fluid Physics Laboratory Department of Engineering MechanicsRoyal Institute of TechnologyStockholmSweden Wallenberg Wood Science Center Royal Institute of TechnologyStockholm SE 10044Sweden Department of Energy and Process Engineering Norwegian University of Science and Technology(NTNU)TrondheimNorway AIMES Center for the Advancement of Integrated Medical and Engineering Sciences at Karolinska Institutet and KTH Royal Institute of Technology StockholmSweden

The combination of flow elasticity and inertia has emerged as a viable tool for focusing and manipulating particles using *** there is considerable interest in the field of elasto-inertial microfluidics owing to its potential applications,research on particle focusing has been mostly limited to low Reynolds numbers(Re<1),and particle migration toward equilibrium positions has not been extensively *** this work,we thoroughly studied particle focusing on the dynamic range of flow rates and particle migration using straight microchannels with a single inlet high aspect *** initially explored several parameters that had an impact on particle focusing,such as the particle size,channel dimensions,concentration of viscoelastic fluid,and flow *** experimental work covered a wide range of dimensionless numbers(0.05

关键词： particle separation straight

From prolonging life to prolonging working life: Tackling unemployment among liver-transplant recipients

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World Journal of Gastroenterology 2016年第14期22卷 3701-3711页

作者： fredrik Aberg Transplantation and Liver Surgery Clinic HUCH Meilahti Hospital Helsinki University 00029 HUS Finland

Return to active and productive life is a key goal of modern liver transplantation(LT). Despite marked improvements in quality of life and functional status, a substantial proportion of LT recipients are unable to resume gainful employment. Unemployment forms a threat to physical and psychosocial health, and impairs LT cost-utility through lost productivity. In studies published after year 2000, the average postLT employment rate is 37%, ranging from 22% to 55% by study. Significant heterogeneity exists among studies. Nonetheless, these employment rates are lower than in the general population and kidneytransplant population. Most consistent employment predictors include pre-LT employment status, male gender, functional/health status, and subjective work ability. Work ability is impaired by physical fatigue and depression, but affected also by working conditions and society. Promotion of post-LT employment is hampered by a lack of interventional studies. Prevention of pre-LT disability by effective treatment of(minimal) hepatic encephalopathy, maintaining mobility, and planning work adjustments early in the course of chronic liver disease, as well as timely post-LT physical rehabilitation, continuous encouragement, self-efficacy improvements, and depression management are key elements of successful employment-promoting strategies. Prolonging LT recipients' working life would further strengthen the success of transplantation, and this is likely best achieved through multidisciplinary efforts ideally starting even before LT candidacy.

关键词： Employment Workforce Transplantation Quality of life Work ability

Effect of rock joints on lined rock caverns subjected to high internal gaspressure

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Journal of Rock Mechanics and Geotechnical Engineering 2023年第7期15卷 1625-1635页

作者： Davi Rodrigues Damasceno Johan Spross fredrik Johansson Division of Soil and Rock Mechanics KTH Royal Institute of TechnologySE-10044StockholmSweden

The storage of hydrogen gas in lined rock caverns(LRCs)may enable the implementation of the firstlarge-scale fossil-free steelmaking process in Sweden,but filling such storage causes joints in the rockmass to open,concentrating strains in the *** structural interaction between the LRC componentsmust be able to reduce the strain concentration in the sealing steel lining;however,this interaction iscomplex and difficult to predict with analytical *** this paper,the strain concentration in LRCsfrom the opening of rock joints is studied using finite element(FE)analyses,where the large-and small-scale deformation behaviors of the LRC are *** model also includes concrete crack initiation anddevelopment with increasing gas pressure and rock joint *** interaction between the jointed rockmass and the reinforced concrete,the sliding layer,and the steel lining is *** results showthat the rock mass quality and the spacing of the rock joints have the greatest influence on the straindistributions in the steel *** largest effect of rock joints on the maximum strains in the steellining was observed for geological conditions of“good”quality rock masses.

关键词： Lined rock cavern(LRC) Rock joints Strain concentrations Lining interaction Finite element(FE)analysis High gas pressure

Efficient construction of linear models in materials modeling and applications to force constant expansions

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npj Computational Materials 2020年第1期6卷 527-537页

作者： Erik Fransson fredrik Eriksson Paul Erhart Department of Physics Chalmers University of TechnologyGothenburgSweden

Linear models,such as force constant(FC)and cluster expansions,play a key role in physics and materials *** they can in principle be parametrized using regression and feature selection approaches,the convergence behavior of these techniques,in particular with respect to thermodynamic properties is not well ***,we therefore analyze the efficacy and efficiency of several state-of-the-art regression and feature selection methods,in particular in the context of FC extraction and the prediction of different thermodynamic properties.

关键词： properties thermodynamic constant

Employing nanoparticle tracking analysis of salivary neuronal exosomes for early detection of neurodegenerative diseases

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Translational Neurodegeneration 2023年第1期12卷 791-800页

作者： Vaibhav Sharma fredrik Nikolajeff Saroj Kumar Department of Health Education and TechnologyLulea University of TechnologyLuleaSweden Department of Biophysics All India Institute of Medical SciencesNew DelhiIndia

Neurodegenerative diseases are a set of progressive and currently incurable diseases that are primarily caused by neuron *** diseases often lead to cognitive impairment and *** is now well recognized that molecular events precede the onset of clinical symptoms by *** the past decade,intensive research attempts have been aimed at the early diagnosis of these ***,exosomes have been shown to play a pivotal role in the occurrence and progression of many diseases including cancer and neurodegenerative ***,because exosomes can cross the blood-brain barrier,they may serve as a diagnostic tool for neural *** this review,we detail the mechanisms and current challenges of these diseases,briefly review the role of exosomes in the progression of neurodegenerative diseases,and propose a novel strategy based on salivary neuronal exosomes and nanoparticle tracking analysis that could be employed for screening the early onset of neurodegenerative diseases.

关键词： Exosomes Parkinson’s disease Alzheimer’s disease Neurodegenerative disease Diagnosis Prognosis Extracellular vesicles Nanoparticle tracking analysis

Rock mass response for lined rock caverns subjected to high internal gas pressure

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Journal of Rock Mechanics and Geotechnical Engineering 2023年第1期15卷 119-129页

作者： Davi Rodrigues Damasceno Johan Spross fredrik Johansson Division of Soil and Rock Mechanics KTH Royal Institute of TechnologySE-10044StockholmSweden

The storage of hydrogen gas in underground lined rock caverns(LRCs)enables the implementation of the first fossil-free steelmaking process to meet the large demand for crude *** the response of rock mass is important to ensure that gas leakage due to rupture of the steel lining does not *** and numerical models can be used to estimate the rock mass response to high internal pressure;however,the fitness of these models under different in situ stress conditions and cavern shapes has not been *** this paper,the suitability of analytical and numerical models to estimate the maximum cavern wall tangential strain under high internal pressure is *** analytical model is derived in detail and finite element(FE)models considering both two-dimensional(2D)and three-dimensional(3D)geometries are *** models are verified with field measurements from the LRC in Skallen,southwestern *** analytical model is inexpensive to implement and gives good results for isotropic in situ stress conditions and large cavern *** the case of anisotropic horizontal in situ stresses,as the conditions in Skallen,the 3D FE model is the best approach.

关键词： Lined rock caverns(LRCs) High pressure Rock mass response In situ stress condition Cavern shape Gas storage

Influence of location of large-scale asperity on shear strength of concrete-rock interface under eccentric load

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Journal of Rock Mechanics and Geotechnical Engineering 2020年第3期12卷 449-460页

作者： Dipen Bista Gabriel Sas fredrik Johansson Leif Lia SINTEF Narvik As Narvik8517Norway Norwegian University of Science and Technology(NTNU) Trondheim7491Norway Royal Institute of Technology(KTH) Stockholm10044Sweden

The location and geometry of large-scale asperity present at the foundation of concrete gravity dams and buttress dams affect the shear resistance of the concrete-rock ***,the parameters describing the frictional resistance of the interface usually do not account for these *** could result in an underestimate of the peak shear stre ngth,which leads to significantly conservative design for new dams or unnecessary stability enhancing measures for existing *** aim of this work was to investigate the effect of the location of first-order asperity on the peak shear strength of a concrete-rock interface under eccentric load and the model discrepancy associated with the commonly used rigid body methods for calculating the factor of safety(FS)against *** this,a series of direct and eccentric shear tests under constant normal load(CNL)was carried out on concrete-rock *** peak shear strengths measured in the tests were compared in terms of asperity location and with the predicted values from analytical rigid body *** results showed that the large-scale asperity under eccentric load significantly affected the peak shear ***,unlike the conventional assumption of sliding or shear failure of an asperity in direct shear,under the effect of eccentric shear load,a tensile failure in the rock or in the concrete could occur,resulting in a lower shear strength compared with that of direct shear *** results could have important implications for assessment of the FS against sliding failure in the concrete-rock interface.

关键词： Shear strength Concrete-rock interface Asperity location Eccentric load Model discrepancy Dam foundation

Frequency Extrapolation through Sparse Sums of Lorentzians

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Journal of Earth Science 2014年第1期25卷 117-125页

作者： fredrik Andersson Marcus Carlsson Maarten V de Hoop Centre for Mathematical Sciences Lund University Department of Mathematics Purdue University

Sparse sums of Lorentzians can give good approximations to functions consisting of linear combination of piecewise continuous functions. To each Lorentzian, two parameters are as- signed： translation and scale. These parameters can be found by using a method for complex fre- quency detection in the frequency domain. This method is based on an alternating projection scheme between Hankel matrices and finite rank operators, and have the advantage that it can be done in weighted spaces. The weighted spaces can be used to partially revoke the effect of finite band-width filters. Apart from frequency extrapolation the method provides a way of estimating discontinuity locations.

关键词： sparse sum Lorentzians Hankel matrices finite rank operator discontinuity location.

文化、族群与生态位——巴基斯坦北部斯瓦特地区族群的生态关系

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文物季刊 2024年第3期 173-179页

作者： [挪威]弗雷德里克·巴斯陈淳(译) 不详

这篇论文写作虽然时间较早,但是对考古学研究影响巨大。挪威民族学家巴斯根据巴基斯坦斯瓦特地区三个不同族群对不同环境的适应、共生和互动,率先将生物学的“生态位”概念引入人类学。这个概念对考古学的启发是,在不同资源呈斑块状分... 详细信息

这篇论文写作虽然时间较早,但是对考古学研究影响巨大。挪威民族学家巴斯根据巴基斯坦斯瓦特地区三个不同族群对不同环境的适应、共生和互动,率先将生物学的“生态位”概念引入人类学。这个概念对考古学的启发是,在不同资源呈斑块状分布的环境里,史前人群的分布很可能也是以各种生态位的适应而彼此共存,不同人群和文化之间的边界很可能是重叠和镶嵌的。本文的四点结论尤其值得深思,可以为我们对许多难以从器物分布得到满意解释的考古现象提供全新的思路。

关键词：考古学研究民族学家论文写作斯瓦特斑块状巴基斯坦族群生态