检索结果-南通市图书馆

作者： (比)弗雷德里克·莱卢(frederic.Laloux)

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重塑组织

作者： (比)弗雷德里克·莱卢(frederic.Laloux)

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玛祖卡舞曲集

2001年

作者：（波）肖邦（frederic.c.opin）曲伊格纳齐·弗里德曼编订

本书收录了著名钢琴家及作曲家肖邦的玛祖卡舞曲，其中包括升f小调、降B大调、a小调、c.调等等。本书内容全面，可供广大音乐工作者及爱好者练习使用。肖邦波兰最伟大的作曲家，是一位为自由、人权呐喊的有着女性般温柔与优雅的诗人... 详细信息

ISBN: (纸本)7540425083

本书收录了著名钢琴家及作曲家肖邦的玛祖卡舞曲，其中包括升f小调、降B大调、a小调、c.调等等。本书内容全面，可供广大音乐工作者及爱好者练习使用。肖邦波兰最伟大的作曲家，是一位为自由、人权呐喊的有着女性般温柔与优雅的诗人，也是迄今为止对欲望与情感最高贵、优雅的诠释者。关于本书的内容，众所周知，各版本之间最大的不同在于选曲

关键词：钢琴谱学科:玛祖卡舞曲地点:波兰年代:近代玛祖卡舞曲

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肖邦波兰舞曲集

Assoc.ation between Exposure to Metals during Pregnanc.,c.ildhood Gut Mic.obiome,and Risk of Intestinal Inflammation in Late c.ildhood

2001年

作者：（波）肖邦（frederic.c.opin）曲）（波）伊格纳齐·弗里德曼编订（徐小芳译）

本书收入波兰作曲家肖邦的升c.调圆舞曲、降e小调圆舞曲、A大调圆舞曲、c.调圆舞曲等11首。

ISBN: (纸本)7540424753

本书收入波兰作曲家肖邦的升c.调圆舞曲、降e小调圆舞曲、A大调圆舞曲、c.调圆舞曲等11首。

关键词：钢琴谱学科:舞曲地点:波兰年代:近代舞曲

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Environment & Health 2024年第10期2卷 739-749页

作者： Vishal Midya Manasi Agrawal Jamil M.Lane c.ris Gennings Leonid Tarassishin Libni A.Torres-Olasc.aga Joseph Eggers Jill K.Gregory Mellissa Pic.er Inga Peter Jeremiah J.Faith Manish Arora Martha M.Tellez-Rojo Robert O.Wright Jean-frederic.c.lombel Shoshannah Eggers Department of Environmental Medic.ne and c.imate Sc.enc. Icahn School of Medicine at Mount SinaiNew York 10029-6574New YorkUnited States Division of Gastroenterology Icahn School of Medicine at Mount SinaiNew York 10029-6574New YorkUnited States c.nter for Molec.lar Predic.ion of Inflammatory Bowel Disease(PREDIc.) Department of Clinical MedicineAalborg UniversityCopenhagen 9220Denmark Department of Genetic. and Genomic.Sc.enc.s Icahn School of MedicineNew York 10029-6574New YorkUnited States c.nter for Researc. on Nutrition and Health National Institute of Public HealthCuernavaca 62508Mexico Department of Immunology and Immunotherapy Icahn School of Medicine at Mount SinaiNew York 10029-6574New YorkUnited States Department of Epidemiology University of Iowa College of Public HealthIowa City 52242 IowaUnited States Instruc.ional Tec.nology Group Icahn School of Medicine at Mount SinaiNew York 10029-6574New YorkUnited States

Alterations to the gut mic.obiome and exposure to metals during pregnanc. have been suggested to impac. inflammatory bowel ***,how prenatal exposure to metals eventually results in long-term effec.s on the gut mic.obiome,leading to subc.inic.l intestinal inflammation,partic.larly during late c.ildhood,has not been *** is also unknown whether suc. an interac.ive effec. drives a spec.fic.subgroup of c.ildren toward elevated susc.ptibility to intestinal *** used an amalgamation of mac.ine-learning tec.niques with a regression-based framework to explore if c.ildren with distinc. sets of gut mic.obes and c.rtain patterns of exposure to metals during pregnanc.(metal−mic.obial c.ique signature)had a higher likelihood of intestinal inflammation,measured based on fec.l c.lprotec.in(Fc.in late *** obtained samples from a well-c.arac.erized longitudinal birth c.hort from Mexic. c.ty(n=108),*** the sec.nd and third trimesters of pregnanc.,11 metals were measured in whole *** mic.obial abundanc.s and Fc.were measured in stool samples from c.ildren 9−11 years of *** Fc.was defined as having Fc.above 100μg/g of *** identified subgroups of c.ildren in whom mic.obial and metal−mic.obial c.ique signatures were assoc.ated with elevated Fc.false disc.very rate(FDR)c.lar,we found two metal−mic.obial c.ique signatures signific.ntly assoc.ated with elevated Fc.(1)low c.sium(c.)and c.pper(c.)in the third trimester and low relative abundanc. of Eubac.erium ventriosum(OR[95%c.]:10.27[3.57,29.52],FDRc. in the third trimester and high relative abundanc.s of Roseburia inulinivorans and Ruminoc.c.us torques(OR[95%c.]:7.21[1.81,28.77],FDRc.ildren with spec.fic.gut mic.obes and spec.fic.exposure patterns to metals during pregnanc. may have higher fec.l c.lprotec.in levels in late c.ildhood,denoting an elevated risk of intestinal inflammation.

关键词： exposome metals mac.ine learning mic.obiome environmental epidemiology intestinal inflammation

c.diaeum Variegatum Hydro Alc.holic.Leaf Extrac.s and Their Frac.ions Inhibit Pro-Inflammatory Mediators in Vitro

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Journal of Biosc.enc.s and Medic.nes 2023年第5期11卷 40-54页

作者： Sylvain Pec.angou Nsangou c.arifa Ngbetkom Mandou c.rine Matsigang Fondjou Vigny Sayal Ngohoba Edie Bric. Enang II Ibrahim Njingou Emmanuel Mfotie Njoya frederic.Nic. Njayou Paul Moundipa Fewou Laboratory of Pharmac.logy and Toxic.logy Department of Bioc.emistry Faculty of Sciences University of Yaounde1 Yaounde Cameroon c.ntre for Quality of Health and Living Faculty of Health and Environmental Sciences Central University of Technology Bloemfontein South Africa

c.diaeum variegatum has been widely investigated for its biologic.l proprieties ranging from the antiamoebic.potential to the phytoc.emic.l analysis. The aim of the present study was to evaluate the anti-inflammatory potential of c. variegatum leaf extrac.s and frac.ions. A primary mac.ophage c.lture ac.ivated by Sac.haromyc.s c.reviseae (Sc. was used to evaluate c.ll c.totoxic.ty and anti-inflammatory potential of the plant extrac.s and frac.ions. Mac.ophages were treated with different c.nc.ntrations (0.1;1;10 and 100 μg/mL) of the extrac.s/frac.ions for the inhibition of 5-lipoxygenase ac.ivity, nitric.oxide (NO) and Tumor Nec.osis Fac.or Alpha (TNF-α) produc.ion. No signific.nt differenc. was observed on c.ll viability in the presenc. of extrac.s and frac.ions at tested c.nc.ntration during the inc.bation period. Extrac.s and frac.ions of c. variegatum inhibited the 5-lipoxygenase ac.ivity, NO and TNF-α produc.ion by viable primary mouse mac.ophages in a c.nc.ntration-dependent manner. The frac.ionation proc.ss inc.eased anti-inflammatory ac.ivity. Among frac.ions, HEF2, HEF3, HEF5, EEF1, EEF3 and EEF5 exhibited the best anti-inflammatory potential. c. variegatum extrac.s and frac.ions exhibited a greater anti-inflammatory potential throughout the inhibition of pro-inflammatory mediators suc. as NO, 5-Lox and TNF-α.

关键词： c. variegatum Anti-Inflammatory 5-Lipoxygenase NO TNF-α

乌鳖口服液对免疫性卵巢早衰小鼠抗透明带抗体c.4+/c.8+,Fas/FasL表达的影响

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乌鳖口服液对免疫性卵巢早衰小鼠抗透明带抗体CD4+/CD8+,Fas/FasL...

在巴黎盆地利用多分量反射资料和VSP描述裂缝性储集层

中华中医药学会中药实验药理分会2014年学术年会

作者：朱萱萱王海丹严士海符蕊 frederic.Lu 南京中医药大学附属医院布朗大学

目的:探讨乌鳖口服液对自身免疫性卵巢早衰小鼠的影响。方法:通过皮下多点注射小鼠透明带3建立自身免疫性卵巢早衰小鼠模型。然后连续4周给予乌鳖口服液进行治疗,每天剂量为(16.5 g/kg)。通过酶联免疫法检测小鼠抗透明带抗体,用免疫组... 详细信息

目的:探讨乌鳖口服液对自身免疫性卵巢早衰小鼠的影响。方法:通过皮下多点注射小鼠透明带3建立自身免疫性卵巢早衰小鼠模型。然后连续4周给予乌鳖口服液进行治疗,每天剂量为(16.5 g/kg)。通过酶联免疫法检测小鼠抗透明带抗体,用免疫组化法测定脾脏T细胞c.4+、c.8+的含量。同时用免疫组化法测定卵巢Fas、FasL蛋白的表达。卵巢和脾脏做病理组织学的分析。结果:乌鳖口服液急性毒性实验显示乌鳖口服液经口给药给予小鼠未能测出LD50,小鼠经口最大给药量实验结果表明:20只小鼠给药后无明显毒性反应,2周内无死亡。因此,乌鳖口服液是安全的药物。模型组小鼠抗透明带抗体的浓度(8.74±0.99U/ml)和c.4+/c.8+比值(1.74±0.31)增加,同时,模型组小鼠卵巢组织的Fas蛋白表达(0.54±0.29)减少,Fas-L蛋白表达(2.25±0.0)增加。与模型组比较,乌鳖口服液组小鼠抗透明带抗体的浓度(7.34±1.21U/ml)明显低于模型组(pc.4+/c.8+比值(1.07±0.14)明显低于模型组(pc.4+/c.8+比值和Fas/FasL系统的作用。

关键词：自身免疫性疾病透明带抗体 c.4+/c.8+ Fas/FasL BALB/c.鼠

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在巴黎盆地利用多分量反射资料和VSP描述裂缝性储集层

应用单次剂量地塞米松可减轻全髋置换术后的运动疼痛

美国勘探地球物理学家学会第65届年会

作者： Xiang-Yang Li c.lin Mac.eth frederic.Lefeuvre Hoc.ne Tabti 孙忠勤 British Geologic.l Survey Scotland British Geologic.l Survey Scotland Total France Institut de Physique du Globe Paris

我们处理和解释9分量（9c.两个水平的和一个垂直的震源的三分量记录）地面地震数据和附近的两个VSP数据,对巴黎盆地中的Dogger组内裂缝性碳酸盐岩储集层特征进行描述。这一点是通过对矢量场各种属性的不同变化达到的。所说的属性是:速...

我们处理和解释9分量（9c.两个水平的和一个垂直的震源的三分量记录）地面地震数据和附近的两个VSP数据,对巴黎盆地中的Dogger组内裂缝性碳酸盐岩储集层特征进行描述。这一点是通过对矢量场各种属性的不同变化达到的。所说的属性是:速度比、偏振、振幅和旅行时差等。为了保持和恢复这些具有诊断与Dogger组有关异常的能力的属性,处理必须要仔细。在Dogger组内,横波各向异性平均为4％,但横向变化很大,有可能理解成孔隙度和渗透率的横向变化,Dogger 组顶面的差异横波振幅表明总的是变暗（点）的。横波偏振剖面揭示出Dogger组内详细的内部分层达六个层段。这在P波剖面上是看不出来的,根据这些波场属性推断出的信息可以广泛的与Duval （1990）的文章中的井间尺度内的储集层属性对比,但具有更详细的横向变化。

关键词：

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麻醉与镇痛 2009年第3期5卷 57-62页

作者： Kenneth J. Kardash frederic.Sarrazin Mic.ael J. Tessler Aria M. Velly 吴进(译) Department of Anesthesia Sir Mortimer B Davis-Jewish General Hospital McGill University Montreal Canada Department of c.nter of c.inic.l Epidemiology and c.mmunity Studies Sir Mortimer B Davis-Jewish General Hospital McGill University Montreal Canada Department of Diagnostic.and Biologic.l Sc.enc.s University of Minnesota Minneapolis Minnesota 不详

背景手术前应用糖皮质激素可以减少手术后恶心，同时也能提高镇痛效果并减少阿片类药物的用量。方法选择50例连续择期脊麻辅助丙泊酚镇静下行初次单侧全髋关节置换术（THA）的患者，手术开始前以随机、双盲、安慰剂对照的方式静脉输注4... 详细信息

背景手术前应用糖皮质激素可以减少手术后恶心，同时也能提高镇痛效果并减少阿片类药物的用量。方法选择50例连续择期脊麻辅助丙泊酚镇静下行初次单侧全髋关节置换术（THA）的患者，手术开始前以随机、双盲、安慰剂对照的方式静脉输注40mg地塞米松或生理盐水。手术后48小时持续使用吗啡静脉自控镇痛，并每6小时口服布洛芬400mg和对乙酰氨基酚650mg。每4小时记录1次静息疼痛评分（0～10数字评分，NRS）、不良反应和患者自控镇痛吗啡的累积使用量，共48小时。在手术后第24小时记录活动时的NRS评分。在手术后第48小时测量25例患者亚组的c.反应蛋白水平。结果地塞米松组手术中对丙泊酚镇静的需求量明显比对照组增加（234．6±160．1VS138．8±122．7mg，P=0．02）。与对照组相比，地塞米松组手术后的运动痛明显减轻（NRS评分：2．7，95％c.：2．2～3．1和6．8，95％c.：6．4～7．2；P〈0．0001）。地塞米松对任何时点的静息疼痛或者累积的吗啡使用量没有显著影响。地塞米松可以显著减少手术后48小时时c.反应蛋白的水平（52．4mg／L，95％c.：28．2。76．6vs 194．2mg／ml，95％c.：168．9—219．4；P〈0．0001）。对照组有7例患者因恶心需要处理，而地塞米松组仅有1例患者需要处理（P=0．05）。结论全髋关节置换术术前静脉给予单次剂量的地塞米松40mg能持续抑制炎性反应，减轻术后24小时的运动痛。

关键词：地塞米松疼痛评分单次剂量全髋置换术运动减轻吗啡静脉自控镇痛全髋关节置换术

Rec.nt advanc.s in seasonal and multi-annual tropic.l c.c.one forec.sting

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Tropic.l c.c.one Researc. and Review 2023年第3期12卷 182-199页

作者： Yuhei Takaya Louis-Philippe c.ron Eric.Blake Franc.is Bonnardot Nic.las Bruneau Joanne c.mp Johnny c.an Paul Gregory Jhordanne J.Jones Namyoung Kang Philip J.Klotzbac. Yuriy Kuleshov Marie-Dominique Leroux Julia F.Loc.wood Hiroyuki Murakami Akio Nishimura Dushmanta R.Pattanaik Tom J.Philp Yohan Rupric.-Robert Ralf Toumi frederic.Vitart Seonghee Won Ruifen Zhan Meteorologic.l Researc. Institute Japan Meteorological AgencyIbarakiJapan Ouranos MontrealCanada National Hurric.ne c.nter National Oceanic and Atmospheric AdministrationMiamiUSA Meteo-Franc. Direction Interregionale pour l'Ocean IndienSaint-Denisde La ReunionFrance Reask LondonUK Bureau of Meteorology VictoriaAustralia c.ty University of Hong Kong Hong KongChina Asia-Pac.fic.Typhoon c.llaborative Researc. c.nter ShanghaiChina Shanghai Typhoon Institute China Meteorological AdministrationShanghaiChina Department of Earth Atmosphericand Planetary SciencesPurdue UniversityWest LafayetteUSA University c.rporation for Atmospheric.Researc. BoulderUSA Department of Geography Kyungpook National UniversityDaeguRepublic of Korea Department of Atmospheric.Sc.enc. Colorado State UniversityFort CollinsUSA Royal Melbourne Institute of Tec.nology(RMIT)University MelbourneAustralia Met Offic. Hadley c.ntre ExeterUK National Oc.anographic.and Atmospheric.Administration/Geophysic.l Fluid Dynamic. Laboratory PrincetonUSA Japan Meteorologic.l Agenc. TokyoJapan India Meteorologic.l Department New DelhiIndia Maximum Information LondonUK Barc.lona Superc.mputing c.nter BarcelonaSpain Department of Physic. Imperial College LondonLondonUK European c.ntre for Medium-Range Weather Forec.sts(Ec.WF) ReadingUK Korea Meteorologic.l Administration JejuRepublic of Korea Department of Atmospheric.and Oc.anic.Sc.enc.s&Institute of Atmospheric.Sc.enc.s Fudan UniversityShanghaiChina

Seasonal tropic.l c.c.one(Tc.forec.sting has evolved substantially sinc. its c.mmenc.ment in the early ***,present operational seasonal Tc.forec.sting servic.s still do not meet the requirements of soc.ety and stakeholders:c.rrent operational produc.s are mainly basin-sc.le information,while more detailed sub-basin sc.le information suc. as potential risks of Tc.landfall is antic.pated for dec.sion *** fill this gap and make the Tc.sc.enc. and servic.s move forward,this paper reviews rec.nt researc. and development in seasonal tropic.l c.c.one(Tc.*** partic.lar,this paper features new researc. topic. on seasonal Tc.predic.ability in neutral c.nditions of El Ni˜no–Southern Osc.llation(ENSO),emerging forec.sting tec.niques of seasonal Tc.ac.ivity inc.uding Mac.ine Learning/Artific.al Intelligenc.,and multi-annual Tc.*** also review the skill of forec.st systems at predic.ing landfalling statistic. for c.rtain regions of the North Atlantic.Western North Pac.fic.and South Indian oc.ans and disc.ss the gap that remains between c.rrent produc.s and potential user's *** knowledge and advanc.d forec.sting tec.niques are expec.ed to further enhanc. the c.pability of seasonal Tc.forec.sting and lead to more ac.ionable and fit-for-purpose produc.s.

关键词： Tropic.l c.c.ones Seasonal forec.sting c.imate servic.s