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Electrocardiographic markers of cardiac resynchronization therapy response:delayed time to intrinsicoid deflection onset in lateral leads

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Journal of Geriatric Cardiology 2022年第1期19卷 21-30页

作者： Rubén KA Tapia-Orihuela S Michael Gharacholou Samuel J Asirvatham freddy del-carpio munoz Department of Medicine Universidad Nacional Mayor de San MarcosFacultad de Medicina de San FernandoLimaPeru Department of Cardiovascular Diseases Mayo ClinicJacksonvilleFLUSA Department of Cardiovascular Diseases Mayo ClinicRochesterMNUSA

Cardiac resynchronization therapy(CRT)has emerged as an important intervention for patients with heart failure(HF)with reduced ejection fraction and delayed ventricular *** these patients,CRT has demonstrated to improve quality of life,promote reverse left ventricular(LV)remodeling,reduce HF hospitalizations,and extend ***,despite advancements in our understanding of CRT,a significant number of patients do not respond to this *** invasive and non-invasive parameters have been assessed to predict response to CRT,but the electrocardiogram(ECG)has remained as the prevailing screening method albeit with ***,an accurate,simple,and reproducible ECG marker or set of markers would dramatically overcome the current *** describe the clinical utility of an old ECG parameter that can estimate ventricular activation delay:the onset to intrinsicoid deflection(ID).Based on the concept of direct measurement of ventricular activation time(intrinsic deflection onset),time to ID onset measures on the surface ECG the time that the electrical activation time takes to reach the area subtended by the corresponding surface ECG *** on this principle,the time to ID on the lateral leads can estimate the delay activation to the lateral LV wall and can be used as a predictor for CRT response,particularly in patients with non-specific intraventricular conduction delay or in patients with left bundle branch block and QRS<150 *** aim of this review is to present the current evidence and potential use of this ECG parameter to estimate LV activation and predict CRT response.

关键词： deflection intrinsic synchronization

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CLT Fabricated with Gmelina arborea and Tectona grandis Wood from Fast-Growth Forest Plantations: Physical and Mechanical Properties

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Journal of Renewable Materials 2022年第1期10卷 1-17页

作者： freddy munoz Carolina Tenorio Roger Moya Angel Navarro-Mora Escuela de Ingenieria Forestal Instituto Tecnologico de Costa RicaCartago159-7050Costa Rica Escuela de Ingenieria en Construccion Instituto Tecnologico de Costa RicaCartago159-7050Costa Rica

Fabrication and use of Cross Laminated Timber(CLT)using tropical woods is still limited at *** objective of the present study aims to determine the possibility of using CLT panels of 3 and 5 layers,fabricated withTectona grandis and Gmelina arborea wood using adhesive of isocyanate polymer emulsion system catalyzed with polymeric ***,water absorption,density,flexure test,compression and glue-line shear were evaluated using ANSI/APA PRG320-2012 ASTM D198 and ASTM D4761 *** results showed that CLT panels of *** presented higher values of density,less water absorption and lower delamination,with no evident differences between the CLT of 3 and 5 *** high density of *** resulted in higher values of the mechanical *** flatwise and edgewise flexure tests in 5-layer CLT panels of both species pre-sented higher values of bending stiffness compared to those of 3-layer CLT *** the bending stress values in 3-layer CLT panels were higher than for 5-layer CLT *** for shear stress in bending flatwise,in both species,3-layer CLT surpassed 5-layer CLT panels,but in the edgewise test no differences were *** MOE and Fc in the compression test were superior in relation to the edgewise *** and Fc in compres-sion flatwise in 3-layer CLT was greater than in 5-layer CLT in both species,but edgewise these values were higher in 5-layer CLT *** most common failures were stress and delamination in the flexure test,whereas in the compression test these were:shearing,splitting and *** the glue-line shear test no differences were observed between CLT panels of 3 and 5 layers for both species.

关键词： Structural elements sustainable material building material tropical wood wood of plantation

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Role of bioengineering structures made of willow cuttings in marly sediment trapping: assessment of three real-size experiments in the Southern French Alps

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Journal of Mountain Science 2018年第2期15卷 225-236页

作者： freddy REY Univ.Grenoble Alpes Irstea Grenoble

Improving knowledge on the ability of bioengineering structures made of willow cuttings to enhance efficient and sustainable sediment trapping in marly gullies in the Southern French Alps under a mountainous Mediterranean climate, to decreasesediment trapped per experiment, the mean annual values reached 0.25, 0.14 and 0.08 m3 yr-1 in experiments C, A and B, respectively. Maximum values for one structure reached 1.94 m3 per year in experiment C. The significance of the volumes ofsediment yield at their outlets, is a key issue today for the international scientific community working in geosciences and ecology. This study therefore aims to assess three real-size experiments(A, B and C) carried out between 2003 and 2013 in this environment. A total of 157 bioengineering structures using purple and white willow(Salix purpurea and Salix incana)cuttings – which have been shown to resprout and survive more than 2 years after their installation,corresponding to brush layers with brush mats on wooden sills(BLM), 1.2 m wide and 2 m long,installed on the floors of 33 experimental marly gullies, were monitored. The results showed that sediment trapping occurred upstream of the vegetation barriers from the 1 st year *** the depth of sediment trapped per experiment, the mean annual values reached 11.2 cm yr-1 after 3 years in experiment A, 7.7 cm yr-1 after 2–4 years in experiment C and 5.1 cm yr-1 after 5 years in experiment B. Occasionally, BLMs showed that they could trap up to 16 and 15 cm yr-1 in experiments A and C, respectively. Considering the volumes oftrapped sediment and the sustainability of sediment trapping are discussed, and rules for bioengineering strategies are proposed.

关键词： Erosion Marly gully Vegetation barriers Ecological engineering Salix

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Extensions of Certain Modules Over the First Weyl Algebra

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Science China Mathematics 1994年第5期37卷 535-546页

作者：肖杰 freddy van Oystaeyen Department of Mathematics Beijing Normal UniversityBeijing 100875PRC Department of Mathematics University of Antwerp UIA Antwerpen B-2610 Belgium

Using a method stemming from the representation theory of finite-dimensional algebra’s,results about a category of Artinian modules over the first Weyl algebra consisting of objects having composition series with composition factors isomorphic to prescribed ones have been *** category corresponds to a tube of Z/2Z type and it is serial and *** Auslander-Reiten formula in this category describing the functor Ext,,(-,-) in terms of the AR-quiver has been *** dimensions of Ext4(M,N) for M and N in different tubes are calculated.

关键词： Weyl algebra Artinian module tube

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Quenching autofluorescence in the alimentary canal tissues of Bactericera cockerelli(Hemiptera:Triozidae)for immunofluorescence labeling

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Insect Science 2020年第3期27卷 475-486页

作者： Xiao-Tian Tang freddy Ibanez Cecilia Tamborindeguy Department of Entomology Texas A&M UniversityCollege StationTexasUSA

Immunofluorescence has been widely used to localize microbes or specific molecules in insect tissues or ***,significant autofluorescence is frequently observed in tissues which can interfere with the fluorescent identification of target antigens,leading to inaccurate or even false positive fluorescent *** alimentary canal of the potato psyllid,Bactericera cockerelliŠulc,exhibits intense autofluorescence,hindering the application of immunolocalization for the detection and localization of the economically important pathogen transmitted by this insect,“Candidatus Liberibacter solanacearum”(Lso).In the present study,we tested the use of irradiation,hydrogen peroxide(H2O2)and Sudan black B(SBB)treatments to reduce the autofluorescence in the *** alimentary canal ***,we assessed the compatibility of the above‐mentioned treatments with Lso immunolocalization and actin staining using *** results showed that the autofluorescence in the alimentary canal was reduced by irradiation,H2O2,or SBB *** compatibility assays indicated that irradiation and H2O2 treatment both greatly reduced the fluorescent signal associated with Lso and ***,the SBB incubation preserved those target signals,while efficiently eliminating autofluorescence in the psyllid alimentary ***,herein we propose a robust method for reducing the autofluorescence in the *** alimentary canal with SBB treatment,which may improve the use of immunofluorescence labeling in this *** method may also have a wide range of uses by reducing the autofluorescence in other arthropod species.

关键词： endosymbionts gut immunofluorescence Liberibacter pathogen psyllid vector

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Planar matrices and arrays of Feynman diagrams

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Communications in Theoretical Physics 2024年第3期76卷 15-32页

作者： freddy Cachazo Alfredo Guevara Bruno Umbert Yong Zhang Perimeter Institute for Theoretical Physics WaterlooON N2L 2Y5Canada Department of Physics and Astronomy University of WaterlooWaterlooON N2L 3G1Canada CECs Valdivia y Departamento de Física Universidad de ConcepciónCasilla 160-CConcepciónChile Center for the Fundamental Laws of Nature Society of Fellows and Black Hole InitiativeHarvard UniversityCambridgeMA 02138United States of America Department of Applied Mathematics Western UniversityLondonON N6A 5B7Canada CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesNo.19A Yuquan RoadBeijing 100049China

Recently,planar collections of Feynman diagrams were proposed by Borges and one of the authors as the natural generalization of Feynman diagrams for the computation of k=3 biadjoint *** collections are one-dimensional arrays of metric trees satisfying an induced planarity and compatibility *** this work,we introduce planar matrices of Feynman diagrams as the objects that compute k=4 biadjoint *** are symmetric matrices of metric trees satisfying compatibility *** introduce two notions of combinatorial bootstrap techniques for finding collections from Feynman diagrams and matrices from *** applications of the first,we find all 693,13612 and 346710 collections for(k,n)=(3,7),(3,8)and(3,9),*** applications of the second kind,we find all90608 and 30659424 planar matrices that compute(k,n)=(4,8)and(4,9)biadjoint amplitudes,*** an example of the evaluation of matrices of Feynman diagrams,we present the complete form of the(4,8)and(4,9)biadjoint *** also start a study of higher-dimensional arrays of Feynman diagrams,including the combinatorial version of the duality between(k,n)and(n-k,n)objects.

关键词： Feynman diagrams biadjoint amplitudes tropical Grassmannian

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Identification of ISSR markers linked to flowering traits in a representative sample of Eucalyptus cladocalyx

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Journal of Forestry Research 2016年第2期27卷 239-245页

作者： Rodrigo Contreras-Soto Paulina Ballesta Eduardo Ruiz freddy Mora Department of Agronomy State University of Maring Department of Botany University of Concepción Institute of Biological Sciences University of Talca

Early flowering and flower abundance have long been considered desirable traits in eucalypt breeding programs. In particular, flowers of Eucalyptus cladocalyx provide a nectar source for the production of honey in arid ecosystems. To identify inter-simple sequence repeat （ISSR） markers that are associated with early flowering and flower abundance in the southern Atacama Desert, we used a sample of 47 trees, representing five Australian prove- nances of E. cladocalyx. A unified mixed linear model （which considered the effect of genetic structure and the kinship relationship among trees） revealed that three loci were significantly associated with early flowering, which accounted for 10-16 % of the phenotypic variation, while two loci accounted for 11-13 % in flowering intensity. Locus ISO1-500 bp was associated with both flowering traits. This result is consistent with our previous findings indicating that marker-assisted selection on early flowering should have significant and positive impact on flowering intensity. The application of marker-assisted selection to identify trees that flower early and intensively may increase honey production, a resource that generates additional income for the local farmers of the southern Atacama Desert.

关键词： Eucalyptus cladocalyx ISSR Floweringtraits Marker-assisted selection

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Influence of BPPV and Meniere's Disease on Cognitive Abilities: A Questionnaire-Based Study

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Journal of Otology 2024年第1期19卷 10-18页

作者： Rohit Bhattacharyya Animesh Barman freddy Antony All India Institute of Speech and Hearing MysoreMysuruIndia

The vestibular system connects the inner ear to the midbrain and subcortical structures and can affect cognition. Patients with vertigo often experience cognitive symptoms such as attention deficits, memory problems, and spatial perception difficulties. This study aimed to explore the cognitive impairments associated with Benign paroxysmal positional vertigo(BPPV) and Meniere's Disease(MD). A non-experimental group comparison design was used with 107 participants divided into three groups: Group I(clinically normal), Group II(BPPV), and Group III(MD). Participants completed a questionnaire with 10 cognition-related questions, and their responses were scored. The data were found to be non-normally distributed. The analysis revealed a significant difference in scores between Group I and both Group II and Group III. Chi-square tests showed that the responses to cognition-related questions varied among the groups, with Group II exhibiting more cognitive problems. Associated conditions like hypertension, diabetes, and hearing loss did not significantly influence the responses within each group. This study suggests a significant relationship between cognitive problems and patients with BPPV and MD. However, there was no association found between the cognitive problems experienced in BPPV and MD patients. These findings align with previous research indicating that vestibular disorders can lead to deficits in spatial memory, attention, and other cognitive functions. By understanding the link between cognition and vestibular disorders, we can improve diagnosis and rehabilitation services to enhance the quality of life for these patients.

关键词： BPPV Meniere's disease Cognition Questionnaire

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The influence of bacteria on multitrophic interactions among plants, psyllids, and pathogen

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Insect Science 2017年第6期24卷 961-974页

作者： Cecilia Tamborindeguy Ordom Brian Huot freddy Ibanez Julien Levy Department of Entomology Texas A&M University College Station Texas USA Department of Horticultural Sciences Texas A&M University College Station Texas USA

The recent emergence ofseveralplant diseases caused by psyllid-borne bacterial pathogens worldwide （Candidatus Liberibaeter spp.） has created renewed interest on the interaction between psyllids and bacteria. In spite of these efforts to understand psyllid association with bacteria, many aspects of their interactions remain poorly understood. As more organisms are studied, subtleties on the molecular interactions as well as on the effects of the bacteria on the psyllid host are being uncovered. Additionally, psyllid-borne bacterial phytopathogens can also affect the host plant, which in turn can impact psyllid physiology and behavior. Here, we review the current literature on different aspects of the influence of bacteria on multitrophic interactions among plants, psyllids, and pathogens. We then highlight gaps that need to be addressed to advance this field, which can have significant implications for controlling these newly emergent and other plant diseases.

关键词： bacteria interaction Liberibacter microbiome phytoplasma psyllid

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The Governance of Natural Resources in the Democratic Republic of Congo

The Governance of Natural Resources in the Democratic Republ...

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作者： MBUYI BATANTE freddy 山东大学

学位级别：硕士

本研究以刚果民主共和国调整自然资源的法律治理为基础,用于改善人类生活不同领域的条件,如保护人民及其财产、收入和运营的透明度、环境管理和社会影响。另—方面,本文在尊重《采掘业透明度倡议》的同时,提供有关收入以及公共和私营企... 详细信息

本研究以刚果民主共和国调整自然资源的法律治理为基础,用于改善人类生活不同领域的条件,如保护人民及其财产、收入和运营的透明度、环境管理和社会影响。另—方面,本文在尊重《采掘业透明度倡议》的同时,提供有关收入以及公共和私营企业的其他数据分析。在遵守国家和国际层面的原则和法律的基础上建立法治,同时,国际采矿公司应遵守刚果《采矿法》,如尊重工人、平民和土著居民的权利,他们的平时居所往往因开发者的利益被勘探开发,却并不享有所蕴藏资源的利益。本研究表明,由于滥用这些自然资源,刚果的国家机构存在弱点,导致人口贫困,缺乏问责制、管理透明度以及对基础机构进行善治所必需的技能的重新分配。本研究发现了刚果国家机构的弱点,其特点是无法执行有关开采自然资源的法律,而腐败导致许多公司违反法规开发这些资源,而不尊重官员。显然,刚果政府促进管理透明度的能力薄弱,武装冲突正在伤害人民。此外,本研究指出,虐待和侵权行为发生在不受国家机构监督的部门,受害者是民众和手工经营者。显然,正如上述谴责的那样,《采矿法》及其执行措施在全国范围内被违反,并且制定也不全面,这也助长了非法开采、向邻国运输毛重状态的矿物、采矿公司不承担社会责任、环境污染、将当地居民从传统生活环境中迁移、掠夺公共公司、强行取代手工经营者占领采矿场,以及反叛运动对非法贸易的控制等现象。在这方面,本研究建议应该建立法治,从而尊重该地区的法律和原则,有效控制刚果与其所有邻国的边界,在大湖国家之间建立共同市场,如为防止采矿欺诈,建议在大湖共同体国家之间缔结贸易、军事、经济协定,在自然资源管理、问责制和收入渠道方面的国际专业知识可以创造—股全新的刚果风气。

关键词：法律治理法治透明度问责制有罪不罚腐败尊重人权国际贸易国际条约

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