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Mathematical epidemiology:Past,present,and future

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Infectious Disease Modelling 2017年第2期2卷 113-127页

作者： fred Brauer University of British Columbia VancouverBCCanada

We give a brief outline of some of the important aspects of the development of mathematical epidemiology.

关键词： Mathematical epidemiology brief

Response of Solanum tuberosum to Myzus persicae infestation at different stages of foliage maturity

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Insect Science 2014年第6期21卷 727-740页

作者： Adriana e. Alvarez Anahi M. Alberti D'Amato W. fred Tjallingii Marcel Dicke Ben Vosman Laboratory of entomology Wageningen University 6700 EH Wageningen Plant Breeding Wageningen UR 6700 AA Wageningen ePG systems 6703CJ Wageningen the Netherlands

Young leaves of the potato Solanum tuberosum L. cultivar Kardal contain resistance factors to the green peach aphid Myzuspersicae （Sulzer）（Hemiptera： Aphididae） and normal probing behavior is impeded. However, M. persicae can survive and reproduce on mature and senescent leaves of the cv. Kardal plant without problems. We compared the settling ofM. persicae on young and old leaves and analyzed the impact of aphids settling on the plant in terms of gene expression. Settling, as measured by aphid numbers staying on young or old leaves, showed that after 21 h significantly fewer aphids were found on the young leaves. At earlier time points there were no difference between young and old leaves, suggesting that the young leaf resistance factors are not located at the surface level but deeper in the tissue. Gene expression was measured in plants at 96 h postinfestation, which is at a late stage in the interaction and in compatible interactions this is long enough for host plant acceptance to occur. In old leaves of cv. Kardal （compatible interaction）, M. persicae infestation elicited a higher number of differentially regulated genes than in young leaves. The plant response to aphid infestation included a larger number of genes induced than repressed, and the proportion of induced versus repressed genes was larger in young than in old leaves. Several genes changing expression seem to be involved in changing the metabolic state of the leaf from source to sink.

关键词： cDNA microarrays green peach aphid insect-plant interactions potato

DeSIGN FOR AVAILABILITY:A HOLISTIC APPROACH TO CReATe VALUe FOR MANUFACTUReRS AND CUSTOMeRS OF CAPITAL GOODS

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Journal of Systems Science and Systems engineering 2012年第4期21卷 403-421页

作者： Lydie P.M.SMeTS Geert-Jan van HOUTUM fred LANGeRAK School of Industrial & Systems engineering Eindhoven University of Technologythe Netherlands

This research introduces a holistic framework called Design for Availablhty that uses me principles of Lean Sigma and Design for X to cost-effectively optimize the availability of capital goods （i.e., technical systems used in the production of end-products or -services such as medical systems, airplanes, and manufacturing equipment） throughout their entire lifetime. Manufacturers require such a framework because users of capital goods increasingly insist on high system availability levels against reduced lifetime costs. The Design for Availability framework allows manufacturers to determine the current status of system availability and associated lifetime costs, and to identify opportunities to create additional value for themselves and their customers. A case study at a global manufacturer of capital goods in the food processing industry illustrates how the framework can be used in practice and to what extent the manufacturer and customers may profit from applying Design for Availability.

关键词： Design for X system availability MTTR MTTF MTTS lifecycle costs capital goods

Collapse of the endemic lizard Podarcis pityusensis on the island of Ibiza mediated by an invasive snake

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Current Zoology 2022年第3期68卷 295-303页

作者： elba MONTeS fred KRAUS Brahim CHeRGUI Juan M.PLeGUeZUeLOS Department of Zoology Faculty of Biological SciencesUniversity of Valenciac/Dr.Moliner50BurjassotE-46100 ValenciaSpain Department of ecology and evolutionary Biology University of MichiganAnn ArborMI 48109USA Laboratoire ecologie SystématiqueConservation de la BiodiversitéFacultédes Sciences de TétouanUniversitéAbdelmalek EssaâdiBP 2121 El M’HannechTétouanMorocco Department of Zoology Faculty of SciencesGranada UniversityGranada E-18071Spain

The invasive snake Hemorrhois hippocrepis colonized the island of Ibiza(Balearic Islands)in 2003 as stowaways inside trunks of olive trees imported for *** has quickly spread since 2010,posing a threat to the island’s only remaining endemic vertebrate,the Ibiza wall lizard Podarcis *** map the yearly expansion rate of the snake and estimate via transect surveys how severely it affects the distribution and abundance of the endemic *** well,we surveyed 9 of 30 small lizard populations on islets surrounding Ibiza that have been isolated since the Last Glacial *** had invaded 49%of Ibiza’s land area by 2018,and censuses show a critical contrast in lizard abundance between areas with and without snakes;almost all censuses in areas without snakes show lizard presence whereas nearly all censuses in areas with *** lack lizard ***,at least one subspecies previously thriving on one of the offshore islets has become extinct,and there have been several snakes recorded swimming between Ibiza and the surrounding ***,lizard populations have been dramatically reduced or have vanished within the range of the snake,and our results quantitatively support upgrading this species’threat level for *** study can inform to programs to manage invasive snake populations and to conservation actions to recover the endemic lizard.

关键词： Balearic Islands conservation extinction Hemorrhois hippocrepis lizard census

An unusual cause of hematemesis:Goiter

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World Journal of Gastroenterology 2006年第33期12卷 5412-5415页

作者： Astrid AM van der Veldt Mohammed Hadithi Marinus A Paul fred G van den Berg Chris JJ Mul-der Mikael e Craanen Department of Gastroenterology VU University Medical Center Amsterdam The Netherlands Department of Surgery VU University Medical Center Amsterdam The Netherlands Department of Radiology VU University Medical Center Amsterdam The Netherlands

Downhill varices are located in the upper part of the esophagus and are usually related to superior vena cava obstruction. Bleeding from these varices is extremely rare. We describe a 77-year-old patient with hematemesis due to downhill varices as a result of recurrent goiter. A right lobe thyroidectomy was carried out with disappearance of the varices.

关键词： Downhill esophageal Varices Goiter Hematemesis

Supporting flexible regulation of crisis management by means of situated artificial institution

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Frontiers of Information Technology & electronic engineering 2016年第4期17卷 309-324页

作者： Maiquel De BRITO Lauren THeVIN Catherine GARBAY Olivier BOISSIeR Jomi fred HUBNeR Federal University of Santa Catarina UFSC/CTC/DAS/PPGEAS-PO Box 476FlorianopolisSC 88040-900Brazil LIG/Universite de Grenoble Grenoble 38041France Laboratoire Hubert Curien UMR CNRS 5516 Institut Henri FayolMINES Saint-EtienneSaint-Etienne 42023France

This paper highlights the use of situated artificial institution(SAI) within a hybrid, interactive,normative multi-agent system to regulate human collaboration in crisis management. Norms regulate the actions of human actors based on the dynamics of the environment in which they are situated. This dynamics results from both environment evolution and actors' actions. Our objective is to situate norms in the environment in order to provide a context-aware crisis regulation. However, this coupling must be a loose one to keep both levels independent and easyto-change in order to face the complex and changing crisis situations. To that aim, we introduce a constitutive level between environmental and normative states providing a loose coupling of normative regulation with environment evolution. Norms are thus no more referring to environmental facts but to status functions, i.e., the institutional interpretation of environmental facts through constitutive rules. We present how this declarative and distinct SAI modelling succeeds in managing the crisis with a context-aware crisis regulation.

关键词： Situated artificial institutions(SAIs) Normative system Tangible interaction Crisis management

Robust H_∞ control for aseismic structures with uncertainties in model parameters

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earthquake engineering and engineering Vibration 2007年第4期6卷 409-416页

作者：宋刚林家浩赵岩 W. Paul Howson fred W Williams State Key Laboratory of Structural Analysis for Industrial equipment Faculty of Vehicle Engineering and Mechanics Dalian University of Technology Cardiff School of engineering Cardiff University Cardiff CF24 3AA Wales U.K.

This paper presents a robust H∞ output feedback control approach for structural systems with uncertainties in model parameters by using available acceleration measurements and proposes conditions for the existence of such a robust output feedback controller. The uncertainties of structural stiffness, damping and mass parameters are assumed to be norm-bounded. The proposed control approach is formulated within the framework of linear matrix inequalities, for which existing convex optimization techniques, such as the LM1 toolbox in MATLAB, can be used effectively and conveniently. To illustrate the effectiveness of the proposed robust H∞ strategy, a six-story building was subjected both to the 1940 e1 Centro earthquake record and to a suddenly applied Kanai-Tajimi filtered white noise random excitation. The results show that the proposed robust H∞ controller provides satisfactory results with or without variation of the structural stiffness, damping and mass parameters.

关键词： structural control robust H∞ control linear matrix inequality dynamic output feedback parameter uncertainty seismic excitation

Pristine point of zero charge (p.p.z.c.) and zeta potentials of boehmite’s nanolayer and nanofiber surfaces

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International Journal of Smart and Nano Materials 2016年第1期7卷 1-21页

作者： Leonid A.Kaledin fred Tepper Tatiana G.Kaledin Department of Chemistry Argonide Corporation291 Power CourtSanfordFL 32771USA

The pristine point of zero charge(p.p.z.c)and zeta potential as a function of pH of boehmite oxide/hydroxide(α-Al_(2)O_(3)·H_(2)O)have been determined for three filter *** active component in the first two filter media is boehmite nanofibers,only 2 nm in diameter and about 300 nm *** nanofibers create high zeta potential(ζtrue≥46 mV)in aqueous solutions in the pH range of 3–*** *** were determined to be 11.60±0.15 for nanofibers grafted onto microglass fibers and 11.40±0.15 for agglomerated *** the third filter media,a boehmite nanolayer in the form of monocrystalline oxide/hydroxide with a thickness of approximately 1.2 nm is electroadhesively deposited onto siliceous support material with large surface area of about 50 m^(2)/g,therefore forming a highly electropositive composite of boehmite nanolayer on the second highly electronegative ***’s oxide-hydroxide nanolayer surface creates high zeta potential(ζtrue≥50 mV)in aqueous solutions in the pH range of 3–*** *** was determined to be 11.38±*** reported values are within accuracy,but they are much higher than the values reported in the literature.X-ray powder diffraction data were supplemented by microscopy,infrared spectroscopy in order to characterize fully synthetic boehmite surfaces.

关键词： Boehmite’s nanolayer pristine point of zero charge(p.p.z.c) zeta potential isoelectric point(i.e.p.)

Dynamics and functions of e‑cadherin complexes in epithelial cell and tissue morphogenesis

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Marine Life Science & Technology 2023年第4期5卷 585-601页

作者： Na Zhang Matthias Häring fred Wolf Jörg Großhans Deqing Kong Department of Biology Philipps University35043 MarburgGermany Göttingen Campus Institute for Dynamics of Biological Networks(CIDBN) Georg August University Göttingen37073 GöttingenGermany

Cell–cell adhesion is at the center of structure and dynamics of epithelial tissue.e-cadherin–catenin complexes mediate Ca^(2+)-dependent trans-homodimerization and constitute the kernel of adherens *** the basic function of cell–cell adhesion,recent progress sheds light the dynamics and interwind interactions of individual e-cadherin–catenin complex with e-cadherin superclusters,contractile actomyosin and mechanics of the cortex and *** nanoscale architecture of e-cadherin complexes together with cis-interactions and interactions with cortical actomyosin adjust to junctional tension and mechano-transduction by reinforcement or weakening of specific features of the *** post-translational modifications such as phosphorylation and glycosylation have been implicated,their role for specific aspects of in e-cadherin function has remained ***,we provide an overview of the e-cadherin complex in epithelial cell and tissue morphogenesis focusing on nanoscale architectures by super-resolution approaches and post-translational modifications from recent,in particular in vivo,***,we review the computational modelling in e-cadherin complexes and highlight how computational modelling has contributed to a deeper understanding of the e-cadherin complexes.

关键词： Nanoscale architectures Phosphorylation Glycosylation Computational modelling