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Nuclear Science and Techniques 2020年第12期31卷 20-31页

作者： Chi-Che Hung fraser king Yun-Chen Yu Chi-Jen Chen Yuan-Chieh Wu Wei-Ting Lin 机构不详

This paper presents a corrosion assessment of copper spent nuclear fuel disposal canisters in crystalline rock,using hydrogeological modeling.A simplified approach is considered,to avoid complex and time-consuming computer *** simplified case is presented as a base case,with changes in the hydrogeological parameters presented as variant *** results show that in Taiwan’s base case,decreasing the hydraulic conductivity of the rock or decreasing the hydraulic conductivity of dikes results in a shorter transport path for sulfide and an increase in corrosion ***,the estimated canister failure time is still over one million years in the variant cases.

关键词： Spent nuclear fuel disposal Corrosion assessment Hydrogeological modeling

An algorithm for family screening for coeliac disease

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World Journal of Gastroenterology 2006年第48期12卷 7805-7809页

作者： Jocelyn S fraser Alistair L king H Julia Ellis Simon J Moodie Ingvar Bjarnason Jill Swift Paul J Ciclitira Division of Nutritional Sciences King's College London United Kingdom Division of Nutritional Sciences King’s College London United Kingdom

AIM: To assess the level of undiagnosed coeliac disease (CD) in relatives of patients affected by the condition. METHODS: We collected blood from 914 relatives of probands. We screened these individuals by ELISA for IgA and IgG tTG antibodies, confirming any positive IgA tTG results with an IgA EMA and looked for evidence of IgA deficiency in those who were IgG tTG positive alone, and performed IgG1 EMA in these individuals. We undertook HLA typing where positive screening was found, and this confirmed a strong prevalence of HLA- DQ2 in the coeliac population. Follow-up small intestinal biopsy was undertaken in cases with positive serological screening, wherever possible. RESULTS:Use of this serological screening algorithm revealed a prevalence of undiagnosed CD in 5%-6% of first degree relatives of probands. CONCLUSION:Our data suggests that first degree relatives of individuals with CD should be screened for this condition.

关键词： Coeliac disease Screening Endomysialantibody Familial study IgA deficiency Prevalence Tissue transglutaminase

Dental anomalies in first-degree relatives of transposed canine probands

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International Journal of Oral Science 2015年第3期7卷 169-173页

作者： Adriana Bartolo Neville Calleja fraser McDonald Simon Camilleri Broadstreet Dental Centre Department of Public Health Medical School University of Malta Dental Institute Department of Orthodontics Kings College London

The aim of this study was to investigate and compare the inheritance pattern and prevalence of inheritable dental anomalies in a sample of patients with maxillary canine—first premolar transposition and their first-degree relatives with a sample of palatally displaced canine families. Thirty-five consecutive maxillary canine—first premolar transposition probands and 111 first-degree relatives were matched to 35 consecutive palatally displaced canine probands and 115 first-degree relatives. These were assessed for palatally displaced canines and incisor-premolar hypodontia. Parental age at birth of the proband was also noted. The results revealed that（i） there is no difference in the overall prevalence of palatally displaced canine or incisor-premolar hypodontia between the groups of relatives;（ii） first-degree relatives of bilateral palatally displaced canine probands have a higher prevalence of palatally displaced canine and incisor-premolar hypodontia than those with unilateral palatally displaced canine; and（iii） maternal age at birth of the maxillary canine—first premolar transposition probands was significantly higher than that of the palatally displaced canine *** results suggest that maxillary canine—first premolar transposition and palatally displaced canine are unlikely to be different genetic entities and also indicate environmental or epigenetic influences on dental development.

关键词： ectopic epigenomics genetics hypodontia orthodontics tooth eruption

Mechanism of delayed conduction of fellow eyes in patients with optic neuritis

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International Journal of Ophthalmology(English edition) 2018年第2期11卷 329-332页

作者： Daniah Alshowaeir Con Yiannikas Clare fraser Alexander Klistorner Department of Ophthalmology University of Sydney Department of Ophthalmology King Saud University Department of Neurology Concord Hospital Department of Neurology Royal North Shore Hospital Australian School of Advanced Medicine Macquarie University

To test the hypothesis that latency delay in the fellow eyes of optic neuritis（ON） patients and to compensate for delayed transmission of visual information, latency change of multi-focal visual evoked potential（mf VEP） traces in fellow eyes of 15 ON patients were analyzed. Patients with low risk（LR） for developing multiple sclerosis（MS） were examined separately from MS patients to isolate effect of cortical plasticity from potential pathological changes in disseminated disease. The small increase in latency in fellow eyes of LR group was statistically not significant. In MS patients, the latency was significantly delayed（P〈0.02）. The magnitude of the latency change in the fellow eyes did not correlate with the severity of latency delay in the affected eyes（R^2〈0.02, P=0.3）. The differences between ON patients with and without MS, reported here, suggest that the presence of disseminated disease plays critical role in latency delay of the fellow eye.

关键词： multi-focal visual evoked potential optic neuritis fellow eyes latency delay

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妈妈油漆房子

棒棒英语（中、英文对照） 2011年第10期 2-5页

作者： Philip king fraser Williamson（图） Jenny（改编）

我们家房子外墙上的漆都已经很旧了。妈，漆刷，她为墙壁准备了一把大刷子，为门和窗妈说：“我要重新油漆一下我们的房子。”

关键词：房子油漆妈妈

Reticular exploration of uranium-based metal-organic frameworks with hexacarboxylate building units

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Nano Research 2021年第2期14卷 376-380页

作者： Zhijie Chen Penghao Li Xuan Zhang Mohammad Rasel Mian Xingjie Wang Peng Li Zhichang Liu Michael O’Keeffe J.fraser Stoddart Omar K.Farha Department of Chemistry and International Institute for Nanotechnology Northwestern University2145 Sheridan RoadEvanstonIllinois 60208USA School of Molecular Sciences Arizona State UniversityTempeArizona 85287USA Institute for Molecular Design and Synthesis Tianjin University92 Weijin RoadTianjin 300072China School of Chemistry University of New South WalesSydneyNSW 2052Australia Department of Chemical&Biological Engineering Northwestern UniversityEvanstonIllinois 60208USA

The rational reticular design of metal-organic frameworks(MOFs)from building units of known geometries is essential for enriching the diversity of MOF *** and intriguing structures,however,can also arise from subtle changes in the rigidity/length of organic linkers and/or synthetic ***,we report three uranium-based MOF structures—i.e.,NU-135X(X=0,1,2)—synthesized from trigonal planar uranyl nodes and triptycene-based hexacarboxylate ligands with variable arm lengths.A new chiral 3,6-connected nuc net was observed in NU-1350,while the extended versions of the ligand led to 3-fold catenated MOFs(NU-1351 and NU-1352)with rare 3,6-connected cml-c3 *** differences in the topology of NU-1350 and NU-1351/NU-1352 could be attributed to the slight distortions of the shorter linker in the former from the ideal trigonal prism geometry to an octahedral geometry when coordinated to the trigonal planar uranyl nodes.

关键词： reticular chemistry uranium-based m etal-organic frameworks(MOFs) hexacarboxylate 3 6-connected net catenation actinide