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“双楔螺棱螺杆改进了单螺棱螺杆挤塑机的性能”

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塑料 1980年第3期 14-19页

作者： j.dekker 朱鸿兴荷兰、阿姆斯特丹市、柯尼里克——希尔实验室

由于对挤塑理论的研究,孕育并问世了一种新型的螺槽横断面为梯形的所谓"双楔螺棱螺杆,即 TW 型螺杆,它作为替代常用的直角螺棱螺杆的一种型式,试验比较结果表明,在大多数情况下,TW 型螺杆具有较大的挤出量和良好的操作稳定性。

关键词：螺杆挤出量聚丙烯聚合物聚烯烃大分子化合物螺棱挤塑机

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农用抗菌素

世界农药 1979年第4期 41-45页

作者： j.dekker 杨慧心

抗菌素是由微生物产生的物质,在很低浓度时,即可抑制或杀死其它微生物,用于农业的抗菌素称农用抗菌素。 1928年Fleming发现青霉素以后,随着青霉素在医疗上用途越来越大,抗菌素成为防治人体和动物细菌性疾病的必要手段。1946年发现了对... 详细信息

抗菌素是由微生物产生的物质,在很低浓度时,即可抑制或杀死其它微生物,用于农业的抗菌素称农用抗菌素。 1928年Fleming发现青霉素以后,随着青霉素在医疗上用途越来越大,抗菌素成为防治人体和动物细菌性疾病的必要手段。1946年发现了对真菌高度活性的抗菌素环己酰亚胺(放线酮)后,使人们认为防治植物病害的抗真菌抗菌素可能变得和防治人类细菌病害的抗菌素一样重要。由于放线酮对植物有一定的药害,所以它的应用受到一定的限制。在美国,用它来防治松树水泡锈病(whiie pine blister rust),樱桃叶斑病(cherry leaf spot)和各

关键词：抗菌素微生物渗透性作用点病原菌真菌病传染病

Dietary supplementation of zinc oxide modulates intestinal functionality during the post-weaning period in clinically healthy piglets

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畜牧与生物技术杂志(英文版) 2024年第1期

作者： Dirkjan Schokker Soumya K.Kar Els Willems Alex Bossers Ruud A.dekker Alfons j.M.jansman

来源：博看期刊评论

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行为医学的定义与范畴：讨论、总结和更新

中华行为医学与脑科学杂志 2017年第6期26卷 485-491页

作者： joost dekker Adrienne Stauder frank j.Penedo 济宁医学院济宁272067 荷兰自由大学医学中心精神系和康复医学系 MB阿姆斯特丹1007 芬兰于韦斯屈莱大学体育与健康科学学院于韦斯屈莱40014 匈牙利塞麦尔维斯大学行为科学研究所布达佩斯1085 美国西北大学社会医学系心理学系精神病学和行为科学系芝加哥60611

背景与目的目前行为医学的定义与范畴仍是25年以前的版本，因此，有必要对国际行为医学会章程中行为医学的定义和范畴进行修改、更新。本文旨在：（1）对建议修改行为医学定义与范畴的国际性讨论加以总结；（2）诚邀中国同道参与讨论。... 详细信息

背景与目的目前行为医学的定义与范畴仍是25年以前的版本，因此，有必要对国际行为医学会章程中行为医学的定义和范畴进行修改、更新。本文旨在：（1）对建议修改行为医学定义与范畴的国际性讨论加以总结；（2）诚邀中国同道参与讨论。方法首先确定需要澄清或修改的问题，然后提出对行为医学定义与范畴进行更新和修改的建议。结果需要澄清或修改的问题包括：行为医学的范畴，行为医学的应用，以及行为医学、精神卫生学、健康心理学和心身医学之间的关系与区别。结论建议将行为医学的定义与范畴修改为：行为医学（behavioralmedicine）是以多学科协作为特点的、涉及与健康和疾病相关的生物医学知识和行为科学知识的发展与整合及其在预防、健康促进、诊断、治疗、康复和护理中应用的领域。行为医学的范畴从生物一行为机制（即与健康和疾病相关的生物医学、心理、社会和文化环境等进程之间的相互作用），延伸至临床诊断与干预以及公共卫生领域。诚邀中国同仁对行为医学的定义与范畴的后续讨论发表观点。

关键词：行为医学定义范畴学科

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Confirmation of a Sub-Saturn-size Transiting Exoplanet Orbiting a G Dwarf:TOI-1194 b and a Very Low Mass Companion Star: TOI-1251 B from TESS

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Research in Astronomy and Astrophysics 2024年第3期24卷 129-143页

作者： jia-Qi Wang Xiao-jun jiang jie Zheng Hanna Kellermann Arno Riffeser Liang Wang Karen A.Collins Allyson Bieryla Lars A.Buchhave Steve B.Howell Elise Furlan Eric Girardin joao Gregorio Eric jensen Felipe Murgas Mesut Yilmaz Sam Quinn Xing Gao Ruo-Yu Zhou frank Grupp Hui-juan Wang CAS Key Laboratory of Optical Astronomy National Astronomical ObservatoriesChinese Academy Of SciencesBeijing 10010China University of Chinese Academy of Sciences Beijing 100049China University Observatory Munich Scheinertrsse 1.D-81679 MunichGemany Max Planck Institute for Extraterrestrial Physics Giessenbachstr.1D-85748 GarchingGermany National Astronomical Observatories/Nanjing Institute of Astronomical Optics&Technology Chinese Academy of SciencesNanjing210042China CAS Key Laboratory of Astronomical Optics&Technology Nanjing Institute of Astronomical Optics&TechnologyNanjing 210042China Center for Astrophysics Harvard&Smithsonian60 Garden Street.CambridgeMA 02138USA National Space Institute Technical University of DenmarkElektrovejDK-2800 KgsLyngbyDenmark NASA Ames Research Center Moffett FieldCA 94035USA NASA Exoplanet Science Institute Caltech/IPACMail Code 100-221200 E.California Blvd.PasadenaCA91125USA Grand Pra Observatory Switzerland Department of Physics Washington UniversitySt.LouisMO 63130.USA Department of Physics and Astronomy Swarthmore CollegeSwarthmorePA 19081USA Instituto de Astrofísica de Canarias(IAC) E-38205 La Laguna.TenerifeSpain Departamento de Astrofísica Universidad de La LagunaSpain Dept.of Astronomy and Space Sciences Ankara UniversityTandogan 06100AnkaraTurkey Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China Urumqi No.1 Senior High School Urumqi 830002China Lijiang Gemini Observatory Lijiang 674199China

We report the confirmation of a sub-Saturn-size exoplanet,TOI-1194 b,with a mass of about 0.456+0.055-0.051M_(j),and a very low mass companion star with a mass of about 96.5±1.5 Mj,TOI-1251 *** candidates provided by the Transiting Exoplanet Survey Satellite(TESS)are suitable for further follow-up observations by ground-based telescopes with small and medium *** analysis is performed based on data from several telescopes worldwide,including telescopes in the Sino-German multiband photometric campaign,which aimed at confirming TESS Objects of Interest(TOIs)using ground-based small-aperture and medium-aperture telescopes,especially for long-period ***-1194 b is confirmed based on the consistent periodic transit depths from the multiband photometric *** measure an orbital period of 2.310644±0.000001 days,the radius is 0.767+0.045-0.041Rj and the amplitude of the RV curve is 69.4_(-7.3)^(+7.9)m s^(-1).TOI-1251 B is confirmed based on the multiband photometric and high-resolution spectroscopic data,whose orbital period is 5.963054+0.000002-0.000001days,radius is 0.947+0.035-0.033 R_(j) and amplitude of the RV curve is 9849_(-40)^(+42)ms^(-1).

关键词： planets and satellites fundamental parameters-planets and satellites gaseous planets-stars fundamental parameters-stars low-mass-methods data analysis-techniques photometric-techniques spectroscopic

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HIV protease:late action to prevent immune detection

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Signal Transduction and Targeted Therapy 2021年第5期6卷 1408-1409页

作者： Konstantin M.j.Sparrer frank Kirchhoff Institute of Molecular Virology Ulm University Medical CenterUlmGermany

A recent study published in Science by Wang and colleagues shows that premature activation of the HIV-1 protease leads to caspase activation and recruitment domain 8(CARD8)inflammasome-mediated pyroptosis of infected macrophages and CD4+T cells(Fig.1).These findings might help to improve approaches aiming to eliminate the latent viral reservoirs upon HIV-1 *** invading viral pathogens trigger the innate immune system and are usually rapidly controlled and eventually *** sense viral intruders via so-called pattern recognition receptors(PRRs)capable of detecting pathogen-associated molecular patterns(PAMPs)allowing discrimination between self and *** many cases,these patterns are viral nucleic acids that show pathogen-specific structures or emerge at the wrong localization in the ***,activation of PRRs by their respective ligands leads to the induction of various anti-viral signaling cascades,among them the inflammasome.

关键词： eventually action eliminate

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杀菌剂抗性鉴别和测量通则

世界农药 1986年第6期 48-50页

作者： S.G.Georgopoulos j.dekker 周明国

植物病原菌对杀菌剂抗性的发展结果使得药剂防治病害失效,进而引起作物损失,对当地和世界粮食生产造成不利影响。因此尽快鉴别和测量杀菌剂抗性、采取适当措施是极为重要的。虽然鉴别和测量抗性的方法各不相同,但是化合物与生物结合这... 详细信息

植物病原菌对杀菌剂抗性的发展结果使得药剂防治病害失效,进而引起作物损失,对当地和世界粮食生产造成不利影响。因此尽快鉴别和测量杀菌剂抗性、采取适当措施是极为重要的。虽然鉴别和测量抗性的方法各不相同,但是化合物与生物结合这一通常的原则是一致的。只有与敏感菌株祖比较才能鉴别抗性菌株。因此确定存在问题的某种病原菌对杀菌剂的敏感性基线是十分必要的,可以用被一般认为对杀菌剂是敏感的野生型菌株进行适当的

关键词：病原菌抗性测定敏感性差异

Spectro-Microscopy of Living Plant Cells

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Molecular Plant 2012年第1期5卷 14-26页

作者： Klaus Hatter Alfred j. Meixner frank Schleifenbaum Center for Plant Molecular Biology （ZMBP） Plant Physiology and Biophysical Chemistry University of Tubingen Auf der Morgenstelle 1 72076 Tuebingen Germany Institute for Physical and Theoretical Chemistry （IPTC） Nano-Optics University of Tubingen Auf der Morgenstelle 8 72076 Tubingen Germany

Spectro-microscopy, a combination of fluorescence microscopy with spatially resolved spectroscopic techni- ques, provides new and exciting tools for functional cell biology in living organisms. This review focuses on recent devel- opments in spectro-microscopic applications for the investigation of living plant cells in their native tissue context. The application of spectro-microscopic methods led to the recent discovery of a fast signal response pathway for the brassi- nosteroide receptor BRI1 in the plasma membrane of living plant cells. Moreover, the competence of different plant cell types to respond to environmental or endogenous stimuli was determined in vivo by correlation analysis of different optical and spectroscopic readouts such as fluorescence lifetime （FLT）. Furthermore, a new spectro-microscopic technique, fluorescence intensity decay shape analysis microscopy （FIDSAM）, has been developed. FIDSAM is capable of imaging low- expressed fluorophore-tagged proteins at high spatial resolution and precludes the misinterpretation of autofluorescence artifacts. In addition, FIDSAM provides a very effective and sensitive tool on the basis of F6rster resonance energy transfer （FRET） for the qualitative and quantitative determination of protein-protein interaction. Finally, we report on the quan- titative analysis of the photosystem I and II （PSI/PSII） ratio in the chloroplasts of living Arabidopsis plants at room tem- perature, using high-resolution, spatially resolved fluorescence spectroscopy. With this technique, it was not only possible to measure PSI/PSII ratios, but also to demonstrate the differential competence of wild-type and carbohydrate-deficient plants to adapt the PSI/PSII ratio to different light conditions. In summary, the information content of standard microscopic images is extended by several dimensions by the use of spectro-microscopic approaches. Therefore, novel cell physiolog- ical and molecular topics can be addressed and valuable insigh

关键词： Fluorescence microscopy FLIM FRET photosystems protein-protein interaction FIDSAM.

How to identify which patients with asymptomatic carotid stenosis could benefit from endarterectomy or stenting

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Stroke & Vascular Neurology 2018年第2期3卷 92-100页

作者： Kosmas I Paraskevas frank j Veith j David Spence Department of Vascular and Endovascular Surgery Royal Free HospitalLondonUK Department of Vascular Surgery New York University Langone Medical CenterNew YorkUSA Department of Vascular Surgery Cleveland ClinicClevelandOhioUSA Stroke Prevention&Atherosclerosis Research Centre Robarts Research InstituteWestern UniversityLondonCanada

Offering routine carotid endarterectomy(CEA)or carotid artery stenting(CAS)to patients with asymptomatic carotid artery stenosis(ACS)is no longer considered as the optimal management of these *** suboptimal,however,is the policy of offering only best medical treatment(BMT)to all patients with ACS and not considering any of them for prophylactic *** the last few years,there have been many studies aiming to identify reliable predictors of future cerebrovascular events that would allow the identification of patients with high-risk ACS and offer a prophylactic carotid intervention only to these patients to prevent them from becoming *** patients with ACS should receive *** present article will summarise the evidence suggesting ways to identify these high-risk asymptomatic individuals,namely:(1)microemboli detection on transcranial Doppler,(2)plaque echolucency on Duplex ultrasound,(3)progression in the severity of ACS,(4)silent embolic infarcts on brain CT/MRI,(5)reduced cerebrovascular reserve,(6)increased size of juxtaluminal hypoechoic area,(7)identification of intraplaque haemorrhage using MRI and(8)carotid *** evidence suggests that approximately 10%-15%of patents with asymptomatic stenosis might benefit from intervention;this will become more clear after publication of ongoing studies comparing stenting or endarterectomy with best medical *** the meantime,no patient should be offered intervention unless there is evidence of high risk of ipsilateral stroke,from modalities such as those discussed here.

关键词： patients carotid stenosis