检索结果-南通市图书馆

Presence of hepcidin-25 in biological fluids: Bile,ascitic and pleural fluids

World Journal of Gastroenterology 2010年第17期16卷 2129-2133页

作者： Jayantha Arnold Arvind Sangwaiya Vijay Manglam frank geoghegan Mark Thursz Mark Busbridge Department of Gastroenterology Ealing Hospital NHS TrustUxbridge RoadLondon UB1 3HWUnited Kingdom Department of Biochemistry Ealing Hospital NHS TrustUxbridge RoadLondon UB1 3HWUnited Kingdom Department of Hepatology St Mary's Hospital NHS TrustImperial CollegePraed StreetLondon W2 1NYUnited Kingdom Department of Clinical Chemistry Charing Cross and Hammersmith Hospital NHS TrustImperial CollegeFulham Palace RoadLondon W6 8RFUnited Kingdom

AIM: To examine body fluids such as ascitic fluid (AF),saliva,bile and pleural effusions for the presence of hepcidin using a novel radioimmunoassay (RIA).METHODS: Serum samples were collected from 25 healthy volunteers (mean age: 36 ± 11.9 years,11 males,14 females).In addition bile was obtained from 12 patients undergoing endoscopic retrograde cholangiopancreatography (mean age: 66.9 ± 16.7 years,M:F = 5:7).Saliva was collected from 17 healthy volunteers (mean age: 35 ± 9.9 years,M:F = 8:9).Pleural and AF were collected from 11 and 16 patients [(mean age: 72 ± 20.5 years,M:F = 7:4) and (mean age: 67.32 ± 15.2 years,M:F = 12:4)],*** biological fluid samples (serum,exudative and transudative fluids) were tested for the presence of hepcidin-25 molecule using ***: Hepcidin-25 was detected in all biological fluids *** mean ± SD hepcidin-25 in serum was 15.68 ± 15.7 ng/mL,bile 7.37 ± 7.4 ng/mL,saliva 3.4 ± 2.8 ng/mL,exudative fluid 65.64 ± 96.82 ng/mL and transudative fluid 14.1 ± 17.8 ng/***: We provide clear evidence that hepcidin-25 is present in bile,saliva,pleural and ascitic *** is likely to play a role here in innate immunity.

关键词： Hepcidin Hepcidin assay Hepcidin in biological fluids Hepcidin in ascitic fluid Bile Exudates Antimicrobial peptides

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：