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Kinetic Slip Boundary Condition for Isothermal Rarefied Gas Flows through Static Non-Planar Geometries Based on the Regularized Lattice-Boltzmann Method

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Communications in Computational Physics 2022年第3期31卷 816-868页

作者： Jean-Michel Tucny David Vidal Sebastien Leclaire francois bertrand Mechanical Engineering Department Polytechnique MontralP.O.Box 6079Stn.CVMontrealQCCANADAH3C 3A7 Chemical Engineering Department Polytechnique MontralP.O.Box 6079Stn.CVMontrealQCCANADAH3C 3A7

The simulation of rarefied gasflows through complex porous media is chal-lenging due to the tortuousflow pathways inherent to such *** Lattice Boltzmann method(LBM)has been identified as a promising avenue to solveflows through complex geometries due to the simplicity of its scheme and its high parallel computational *** has been proposed to model the stress-strain relationship with the extended Navier-Stokes equations rather than attempting to directly solve the Boltzmann ***,a regularization technique is required tofilter out non-resolved higher-order components with a low-order velocity *** slip boundary conditions(BCs)have been proposed for the non-regularized multiple relaxation time LBM(MRT-LBM)for planar geometries,previous slip BCs have never been verified extensively with the regularization *** this work,following an extensive literature review on the imposition of slip BCs for rarefiedflows with the LBM,it is proven that earlier values for kinetic parameters developed to impose slip BCs are inaccurate for the regularized MRT-LBM and differ between the D2Q9 and D3Q15 *** error was eliminated for planarflows and good agreement be-tween analytical solutions for arrays of cylinders and spheres was found with a wide range of Knudsen numbers.

关键词： Lattice Boltzmann method(LBM) boundary condition(BC) rarefiedflow nonplanar geometry

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新型佐剂增强禽类疫苗保护

新型佐剂增强禽类疫苗保护

MontanideTM ISA 71 VG:具有细胞免疫反应的禽类疫苗用的新佐剂

中国畜牧兽医学会2014年学术年会

作者： francois bertrand Juliette Ben Arous Jerome Gaucheron Laurent Dupuis 赛彼科(上海)特殊化学品有限公司 SEPPIC 22 Terrasse BelliniParis La Defense92806 PuteauxCedexFrance

目前,用于制备油包水剂型的矿物油佐剂,已广泛应用于禽类疫苗中,它可诱导强烈长期的体液免疫反应。同时,需要一种能够增强禽类疫苗短期和长期的保护的新型佐剂,以配制更稳定有效的多价疫苗,并能扩展疫苗针对不同病毒株或血清的交叉保护...

目前,用于制备油包水剂型的矿物油佐剂,已广泛应用于禽类疫苗中,它可诱导强烈长期的体液免疫反应。同时,需要一种能够增强禽类疫苗短期和长期的保护的新型佐剂,以配制更稳定有效的多价疫苗,并能扩展疫苗针对不同病毒株或血清的交叉保护。针对这些问题,我们研发了2款应用于油包水的

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MontanideTM ISA 71 VG:具有细胞免疫反应的禽类疫苗用的新佐剂

Inverse Scattering for a Schr■dinger Operator with a Repulsive Potential

中国畜牧兽医学会禽病学分会第十六次学术研讨会

作者： francois bertrand Sbastien Deville Juliette Ben Arous Laurent Dupuis SEPPIC中国办事处 SEPPIC 22 Terrasse BelliniParis La Defense92806 Puteaux Cedex法国

介绍矿物油包水的佐剂诱导很强的长期体液免疫反应,被广泛用于禽类疫苗。新佐剂可以同时增强细胞免疫反应,从而增强禽用疫苗的有效性。例如,这种佐剂能够帮助扩展疫苗对不同病毒株或血清型的交叉保护。Montanide ISA 71 VG(ISA 71)是矿... 详细信息

介绍矿物油包水的佐剂诱导很强的长期体液免疫反应,被广泛用于禽类疫苗。新佐剂可以同时增强细胞免疫反应,从而增强禽用疫苗的有效性。例如,这种佐剂能够帮助扩展疫苗对不同病毒株或血清型的交叉保护。Montanide ISA 71 VG(ISA 71)是矿物油包水的佐剂,专为刺激细胞免疫而制备[1].ISA71是基于一种浓缩的轻质矿物油,可以激发体液和细胞免疫反应,ISA 71含有一种从来源于植物的甘露醇和纯油酸中提取并特别精炼的乳化剂。在此研究中,我们显示了Montanide ISA 71 VG是一种安

关键词：禽用疫苗细胞免疫反应新佐剂

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Acta Mathematica Sinica,English Series 2006年第5期22卷 1485-1492页

作者： francois NICOLEAU Laboratoire de Mathéatiques Jean Leray UMR CNRS-UN 6629 Département de Mathématiques2 rue de la Houssinière BP 92208 F-44322 Nantes cedex 03 France

We consider a pair of Hamiltonians （H, H0） on L2（R^n）, where H0=p^2 -x^2 is a SchrSdinger operator with a repulsive potential, and H = H0＋V（x）. We show that, under suitable assumptions on the decay of the elect... 详细信息

关键词： Inverse scattering Repulsive potential

Visualization of bHLH transcription factor interactions in living mammalian cell nuclei and developing chicken neural tube by FRET

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Cell Research 2006年第6期16卷 585-598页

作者： francois Guillemot UK London NW7 1AA Mill Hill Division of Molecular Neurobiology National Institute for Medical Research The Ridgeway

Members of the basic helix-loop-helix(bHLH)gene family play important roles in vertebrate *** thisstudy,confocal microscopy-based fluorescence resonance energy transfer(FRET)is used to monitor bHLH protein-proteininteractions under various physiological ***-specific bHLH activators,NeuroD1,Mashl,Neurogeninl(Ngn1),Neurogenin2(Ngn2),and ubiquitous expressed E47 protein are tagged with enhanced yellow fluorescenceprotein(EYFP)and enhanced cyan fluorescence protein(ECFP),*** subcellular localization and mobilityof bHLH fusion proteins are examined in HEK293 *** transient transfection and in ovo electroporation,four pairsof tissue-specific bHLH activators and E47 protein are over-expressed in HEK293 cells and developing chick embryoneural *** the acceptor photobleaching method,FRET could be detected between these bHLH protein pairs inthe nuclei of transfected cells and developing neural ***/E47 and Ngn2/E47 FRET pairs show higher FRETefficiencies in the medial and the lateral half of chick embryo neural tube,*** suggests that these bHLHprotein pairs formed functional DNA-protein complexes with regulatory elements of their downstream target genes inthe specific *** work will help one understand the behaviours of bHLH factors in vivo.

关键词： bHLH confocal microscopy chick embryo neural tube FRET in ovo electroporation photobleach

Conditions for Set Agreement with an Application to Synchronous Systems

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Journal of Computer Science & Technology 2009年第3期24卷 418-433页

作者： francois Bonnet Michel Raynal IRISA University of Rennes35042 Rennes CedexFrance

The k-set agreement problem is a generalization of the consensus problem： considering a system made up of n processes where each process proposes a value, each non-faulty process has to decide a value such that a decided value is a proposed value, and no more than k different values are decided. While this problem cannot be solved in an asynchronous system prone to t process crashes when t≥ k, it can always be solved in a synchronous system; [t/k]＋1 is then a lower bound on the number of rounds （consecutive communication steps） for the non-faulty processes to decide. The condition-based approach has been introduced in the consensus context. Its aim was to both circumvent the consensus impossibility in asynchronous systems, and allow for more efficient consensus algorithms in synchronous systems. This paper addresses the condition-based approach in the context of the k-set agreement problem. It has two main contributions. The first is the definition of a framework that allows defining conditions suited to the l-set agreement problem and the second is a generic synchronous k-set agreement algorithm based on conditions.

关键词： agreement problem condition efficiency lower bound synchronous system

Discrete Duality Finite Volume Discretization of the Thermal-P_(N) Radiative Transfer Equations on General Meshes

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Communications in Computational Physics 2022年第2期31卷 398-448页

作者： francois Hermeline Universite Paris-Saclay Laboratoire en Informatique Haute Performance pour le Calcul et la simulationCEADAMDIF91297 ArpajonFrance

The discrete duality finite volume method has proven to be a practical tool for discretizing partial differential equations coming from a wide variety of areas of physics on nearly arbitrary *** main ingredients of the method are:(1)use of three meshes,(2)use of the Gauss-Green theorem for the approximation of derivatives,(3)discrete integration by *** this article we propose to extend this method to the coupled grey thermal-P_(N) radiative transfer equations in Cartesian and cylindrical coordinates in order to be able to deal with two-dimensional Lagrangian approximations of the interaction of matter with *** stability under a Courant-Friedrichs-Lewy condition and the preservation of the diffusion asymptotic limit are proved while the experimental second-order accuracy is observed with manufactured *** numerical experiments are reported which show the good behavior of the method.

关键词： Hybrid multiscale models radiative transfer equation grey P_(N)approximation discrete duality finite volume method

Maximizing the Delivery of MPR Broadcasting Under Realistic Physical Layer Assumptions

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Journal of Computer Science & Technology 2008年第3期23卷 451-460页

作者： francois Ingelrest David Simplot-Ryl LCAV EPFLCH-1015LausanneSwitzerland IRCICA/LIFL CNRS UMR 8022Univ.Lille 1INRIA Lille-Nord EuropeFrance

It is now commonly accepted that the unit disk graph used to model the physical layer in wireless networks does not reflect real radio transmissions, and that a more realistic model should be considered for experimental simulations. Previous work on realistic scenarios has been focused on unicast, however broadcast requirements are fundamentally different and cannot be derived from the unicast case. Therefore, the broadcast protocols must be adapted in order to still be efficient under realistic assumptions. In this paper, we study the well-known multipoint relay broadcast protocol （MPR）, in which each node has to choose a set of 1-hop neighbors to act as relays in order to cover the whole 2-hop neighborhood. We give experimental results showing that the original strategy used to select these multipoint relays does not suit a realistic model. On the basis of these results, we propose new selection strategies solely based on link quality. One of the key aspects of our solutions is that our strategies do not require any additional hardware and may be implemented at the application layer, which is particularly relevant to the context of ad hoc and sensor networks where energy savings are mandatory. We finally provide new experimental results that demonstrate the superiority of our strategies under realistic physical assumptions.

关键词： ad hoc network multipoint relay broadcasting realistic physical layer sensor network

The Micromechanics of Biological and Biomimetic Staggered Composites

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Journal of Bionic Engineering 2012年第4期9卷 446-456页

作者： Sacheen Bekah Reza Rabiei francois Barthelat Department of Mechanical Engineering McGill University 817 Sherbrooke Street West Montreal QC H3A 2K6 Canada

Natural materials such as bone, tooth and nacre achieve attractive properties through the ＂staggered structure＂, which consists of stiff, parallel inclusions of large aspect ratio bonded together by a more ductile and tougher matrix. This seemingly simple structure displays sophisticated micromechanics which lead to unique combinations of stiffness, strength and toughness. In this article we modeled the staggered structure using finite elements and small Representative Volume Elements （RVEs） in order to explore microstructure-property relationships. Larger aspect ratio of inclusions results in greater stiffiless and strength, and also significant amounts of energy dissipation provided the inclusions do not fracture in a brittle fashion. Interestingly the ends of the inclusions （the junctions） behave as crack-like features, generating theoretically infinite stresses in the adjacent inclusions. A fracture mechanics criterion was therefore used to predict the failure of the inclusions, which led to new insights into how the interfaces act as a ＂＇soft wrap＂ for the inclusions, completely shielding them from excessive stresses. The effect of statistics on the mechanics of the staggered structure was also assessed using larger scale RVEs. Variations in the microstructure did not change the modulus of the material, but slightly decreased the strength and significantly decreased the failure strain. This is explained by strain localization, which can in turn be delayed by incorporating waviness to the inclusions. In addition, we show that the columnar and random arrangements, displaying different deformation mechanisms, lead to similar overall prop- erties. The guidelines presented in this study can be used to optimize the design of staggered synthetic composites to achieve mechanical performances comparable to natural materials.

关键词： biological materials biomimetics representative volume element fracture mechanics finite element analysis