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Association between lifestyle factors and thyroid function in young euthyroid adults

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Food Science and Human Wellness 2022年

作者： Elisa Merchan-Ramirez Guillermo Sanchez-Delgado Lucas Jurado-Fasoli francisco M Acosta Manuel mu?oz-Torres Jose M.Llamas-Elvira Jonatan R Ruiz Nuclear Medicine Service， "Virgen de las Nieves" University Hospital Sport and Health University Research Institute (imuDS)， Faculty of Sports Science， University of Granada Pennington Biomedical Research Center School of Medicine， University of Granada Turku PET Centre， University of Turku Turku PET Centre， Turku University Hospital Instituto de Investigación Biosanitaria Granada (Ibs.Granada) Department of Medicine， University of Granada Endocrinology and Nutrition Service， University Hospital San Cecilio

Purpose: The present work examines the associations of dietary habits， sedentarism， physical activity (PA) levels and sleep habits， with thyroid function in young euthyroid adults. Methods: A total of 105 young euthyroid adults participated in this cross-sectional study. Thyroid function was determined in fasting conditions (> 6 h). Dietary habits were measured by a food frequency questionnaire and three non-consecutive 24 h recalls， and different dietary intake and patterns were then estimated. The time spent in sedentary， PA levels and sleep habits were objectively measured using a wrist-worn accelerometer. Results: Energy and carbohydrate intake were positively associated with thyroid stimulating hormone (TSH) (β = 0.222; R2= 0.102; P = 0.022 and β = 0.425; R2= 0.129; P = 0.007， respectively) whereas fat intake was negatively associated with TSH (β = -0.428; R2= 0.137; P = 0.004). Energy intake was also positively associated with free triiodothyronine (β = 0.277; R2= 0.137; P = 0.004). Further， adherence to the Mediterranean diet was negatively related to TSH and free thyroxine (FT4) (β = -0.221; R2= 0.113; P = 0.020 and β = -0.268; R2= 0.071; P = 0.007， respectively). Vigorous-intensity and overall PA were negatively associated with FT4 (β = -0.227; R2= 0.052; P = 0.022 and β = -0.204; R2= 0.042; P = 0.041， respectively). In contrast， no associations were found between sleep parameters and thyroid function. Conclusions: Lifestyle factors such as dietary intake and PA levels seems to be related to thyroid function in young euthyroid adults.

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Potential benefits of amino acid supplementation for cervid performance and nutritional ecology,with special focus on lysine and methionine:A review

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Animal Nutrition 2022年第4期11卷 391-401页

作者： Veit Ny Tersia Needham francisco Ceacero Department of Animal Science and Food Processing Faculty of Tropical AgriSciencesCzech University of Life Sciences PragueCzech Republic Department of Cattle Breeding Institute of Animal SciencePragueCzech Republic Food Research Institute Prague Czech Republic

Deer farming is a thriving industry for venison,velvet antlers,trophy hunting,and other *** and nutrition are important factors for improving production performance,especially dietary protein and amino acids(AAs),as they are the main components of all *** a few studies on AA supplementation(Lys,Met,Arg)have been performed on cervids,which show positive effects on weight gain,ADG,feed-:gain ratio,plasma AAs,carcass weight,dressing percentage,yield of high-quality muscles,storage of internal fat during winter,DM and CP digestibility,plasma protein-and fat-related metabolite concentrations,antler burr perimeter,weight,length and mineralisation,velvet antler yield,rumen volatile fatty acids,and microbiome *** these effects are relevant for supporting the production of cervids products,from venison to velvet or trophy antlers,as well as their general performance and well-being of captive-bred *** current available information suggests that AA supplementation can be especially interesting for animals fed low protein rations,and growing animals,but should be avoided in high rations and during winter,since it may promote the accumulation of internal *** effects on milk production and the concentrations of different hormones involved in the regulation of the antler cycle should be further explored.

关键词： Antler Deer Feed additive Protein Ruminant Venison

Assessment of myocardial viability using a minimally invasive laser Doppler flowmetry on pig model

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Journal of Innovative Optical Health Sciences 2021年第2期4卷 51-57页

作者： Karina Litvinova Berthold Stegemann francisco Leyva Aston Medical School Aston University Aston TriangleB47ETBirminghamUK Cardiology Department Queen Elizabeth Hospital Mindelsohn WayB152THBirminghamUK

Background:The intra-operative real-time assessment of tissue viability can potentially improve therapy delivery and clinical outcome in cardiovascular *** ablation therapy for the treatment of supraventricular or ventricular arrhythmia continues to be done without being able to assess if the intended lesion and lesion size have been ***,we report a method for continuous measurements of cardiac muscle microcirculation to provide an instrument for real-time ablation ***:We performed two acute open chest animal studies to assess the ability to perform real-time monitoring of creation and size of ablation lesion using a standard RF irrigated *** ablation and laser Doppler were applied to different endocardial areas of alive open-chest ***:We performed two experiments at three different RF ablation energy setting and different ablation ***-fusion signals before and after ablation were found extensively and distinctively *** in-creasing the ablation energy and time,the perfusion signal was ***:In vivo assessing the local microcirculation during RF ablation by laser Doppler can potentially be useful to differentiate between viable and nonviable ablated beating heart in real time.

关键词： Beating heart RF ablation perfusion real-time monitoring myocardial microcirculation

Solving Delay Differential Equations through RBF Collocation

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Advances in Applied Mathematics and Mechanics 2009年第2期1卷 257-272页

作者： francisco Bernal Gail Gutierrez Institute for Scientific Computing Technical University of Dresden 01062 DresdenGermany Cir 1 No.73-34 Instituto de Energia y TermodinamicaUniversidad Pontificia BolivarianaMedellinColombia

A general and easy-to-code numerical method based on radial basis functions(RBFs)collocation is proposed for the solution of delay differential equations(DDEs).It relies on the interpolation properties of infinitely smooth RBFs,which allow for a large accuracy over a scattered and relatively small discretization ***’s multiquadric is chosen as RBF and combined with the Residual Subsampling Algorithm of Driscoll and Heryudono for support *** performance of the method is very satisfactory,as demonstrated over a cross-section of benchmark DDEs,and by comparison with existing general-purpose and specialized numerical schemes for DDEs.

关键词： Meshless method delay differential equations radial basis function multiquadric adaptive collocation

Nanoscale interactions between the nicotinic acetylcholine receptor and cholesterol

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BIOCELL 2021年第6期45卷 1479-1484页

作者： francisco J.BARRANTES Laboratory of Molecular Neurobiology Institute of Biomedical Research(BIOMED)UCA-CONICETFaculty of Medical SciencesBuenos AiresArgentina

Cholesterol is a major lipid in biological *** not only plays a structural role but also modulates a wide range of functional properties of neurotransmitter and hormone receptors and ion *** membraneembedded segments of the paradigm neurotransmitter receptor for acetylcholine(nAChR)contain linear sequences of amino acids with the capacity to recognize *** cholesterol consensus domains have been designated as“CARC”and its mirror sequence“CRAC”.CARC preferentially occurs in the exoplasmic-facing membrane leaflet,and CRAC,in the cytoplasmic-facing *** motifs are highly conserved among ion-channel and neurotransmitter receptor proteins in vertebrate nervous systems,where they recognize cholesterol,and in prokaryotic homologues in bacteria,where they recognize *** phylogenetically conserved trait is an indication that the hopanoids in some bacteria and cholesterol in eukaryotes subserve analogous functions,probably contributing to the stability of membrane-embedded protein *** studies from our laboratory using superresolution optical microscopy(“nanoscopy”)have disclosed other interrelated functional and structural properties exerted by cholesterol on the *** neutral lipid content at the cell surface influences both the macromolecular organization of the receptor and its translational mobility(diffusion)in the plane of the membrane.

关键词： Cholesterol Pentameric ligand-gated ion channel Nicotinic acetylcholine receptor Membrane proteins Evolution Nanoscopy Cholesterol-recognition domains

A Method of Characterizing Radio Signal Space for Wireless Device Localization

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Tsinghua Science and Technology 2015年第4期20卷 385-408页

作者： John-Austen francisco Richard P.Martin Department of Computer Science Rutgers University

In this work we present a novel approach for describing radio signal spaces for localization algorithms. We first introduce a new metric, the Discretely Distributed Log-H61der Metric （DDLHM）. The DDLHM is designed to characterize the type and degree of signal distortion relative to Iognormal signal-to-distance path models. We first show how the DDLHM can describe and discriminate distortions in an exhaustive set of synthetic signal spaces. We then determine a reduced set of maximally diagnostic distortion parameters. Using only 4% of the maximal set of DDLHMs, we found the reduced set matches with an acceptable degree of error 95% of the time. Using the synthetic reduced set, we characterized a variety of wireless localization algorithms＇ behaviors to attenuation, bias, and multipath. We found algorithms made much different tradeoffs between best case and average case error. We then use the DDLHM to identify distortion types in three different physical environments using measured 802.11 signal strengths, and predict the positioning performance of several localization algorithms. Our approach predicts average localization error to within 2 meters of the observed average error.

关键词： radio propgation 802.11 WiFi

Palm oil biodiesel:An assessment of PAH emissions,oxidative potential and ecotoxicity of particulate matter

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Journal of Environmental Sciences 2021年第3期33卷 326-338页

作者： Silvana Arias francisco Molina John R.Agudelo Grupo de Investigación en Gestión y Modelación Ambiental-GAIA Escuela AmbientalFacultad de IngenieríaUniversidad de Antioquia UdeACalle 70 No.52-21MedellínColombia Departamento de Ingeniería Mecánica Universidad de Antioquia UdeA

This work assessed the impact of fuelling an automotive engine with palm biodiesel(pure,and two blends of 10%and 20%with diesel,B100,B10 and B20,respectively)operating under representative urban driving conditions on 17 priority polycyclic aromatic hydrocarbon(PAH)compounds,oxidative potential of ascorbic acid(OP^(AA)),and ecotoxicity through D aphnia pulex mortality *** diluted with filtered fresh air(WD)gathered in a minitunel,and particulate matter(PM)collected directly from the exhaust gas stream(W/oD)were used for *** showed that PM collecting method significantly impact PAH *** all PAH appeared in both,WD and W/oD,higher concentrations were obtained in the last *** biodiesel concentration in the fuel blend decreased all PAH compounds,and those with 3 and 5 aromatic rings were the most *** biodiesel affected both OP^(AA)and *** B10 and B20 exhibited the same rate of ascorbic acid(AA)depletion,B100 showed significant faster oxidation rate during the first four minutes and oxidized 10%more AA at the end of the test.B100 and B20 were significantly more ecotoxic than *** lethal concentration LC50 for B10 was 6.13 mg/*** was concluded that palm biodiesel decreased PAH compounds,but increased the oxidative potential and ecotoxicity.

关键词： Biodiesel Particulate matter P emissions Oxidative stress Ecotoxicity Daphnia pulex

Bi-objective mathematical model for choosing sugarcane varieties with harvest residual biomass in energy cogeneration

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International Journal of Agricultural and Biological Engineering 2012年第3期5卷 50-58页

作者： francisco Regis Abreu Gomes Coordination of Natural Resources Federal Institute of EducationScience and Technology of CearáRoad o f CedroQuixadáCEBrazil

Sugarcane crop occupies an area of about 23.78 million hectares in 103 countries,and an estimated production of 1.66 billion tons,adding to this volume more than 6%to 17%concerning residual biomass resulting from *** destination of this residual biomass is a major challenge to managers of *** are at least two alternatives which are reduction in residue production and increased output in electricity *** two conflicting objectives are mathematically modeled as a bi-objective *** study developed a bi-objective mathematical model for choosing sugarcane varieties that result in maximum revenue from electricity sales and minimum gathering cost of sugarcane harvesting residual *** approach used to solve the proposed model was based on theε-constraints *** were performed using real data from sugarcane varieties and costs and showed effectiveness of model and method *** experiments showed the possibility of increasing net revenue from electricity sale,i.e.,already discounted the cost increase with residual biomass gathering,in up to 98.44%.

关键词： sugarcane harvested residual biomass bi-objective mathematical programming ε-constraints method energy cogeneration

Diffusion dynamics and characterization of attogram masses in optically trapped single nanoparticles using laser-induced plasma imaging

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Nano Research 2023年第5期16卷 7470-7480页

作者： Pablo Purohit francisco J.Fortes Javier Laserna UMALASERLAB Departamento de Química AnalíticaUniversidad de MálagaC/Jiménez Fraud 4Malaga 29010Spain Niels Bohr Institute University of CopenhagenBlegdamsvej 172100 CopenhagenDenmark

In the present work,a wavelength-selected plasma imaging analysis system is presented and used to track photons emitted from single-trapped nanoparticles in air at atmospheric *** isolated nanoentities were atomized and excited into plasma state using single nanosecond laser *** use of appropriate wavelength filters alongside time-optimized acquisition settings enabled the detection of molecular and atomic emissions in the *** photon detection efficiency of the imaging line resulted in a signal>400 times larger than the simultaneously-acquired dispersive spectroscopy *** increase in sensitivity outlined the evolution of diverse physicochemical processes at the single particle scale which included heat and momentum transfer from the plasma into the particle as wells as chemical *** imaging detection of excited fragments evidenced different diffusion kinetics and time frames for atoms and molecules and their influence upon both the spectroscopic emission readout and fabrication processes using the plasma as a ***,the origin of molecular species,whether naturally-occurring or derived from a chemical reaction in the plasma,could also be studied on the basis of compositional gradients found on the *** of detection for the inspected species ranged from tens to hundreds attograms,thus leading to an exceptional sensing principle for single nanoentities that may impact several areas of science and technology.

关键词： single nanoparticle inspection wavelength-selected laser-induced plasma imaging laser fabrication attogram characterization atomic/molecular diffusion