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Journal of Modern Physics 2015年第11期6卷 1679-1694页

作者： néstor David Espinosa-Torres José álvaro David Hernández de la Luz José francisco javier Flores-Gracia José Alberto Luna-López javier martínez-Juárez Gregorio Flores-Carrasco IC-CIDS Benemérita Universidad Autónoma de Puebla Puebla México Ex Graduate Research Trainee at Plasma Processing Laboratory Chemical Engineering Department McGill University Montreal Canada Department of Materials Science and Engineering and Chemical Engineering University Carlos III of Madrid and IAAB Madrid Spain

The Global Reaction Model describes a set of chemical reactions that can potentially occur during the process of obtaining silicon rich oxide (SRO) films, regardless of the technique used to grow such films which are an outside stoichiometry material. Particularly, chemical reactions that occur during the process of growing of SRO films by LPCVD technique are highlighted in this model. We suggest and evaluate either some types of molecules or resulting nanostructures and we predict theoretically, by applying the density functional theory, the contribution that they may have to the phenomenon of luminescence which is measured in SRO films. Also, we have calculated the opto-electronic properties of SRO films. The suggested model provides enough information required to identify the molecular structures resulting from the presence of defects in SRO films and also those corresponding to charged structures. It is also possible to detect the molecular structures which are modified due to the effect of heat treatment, and identify the presence of different oxidation states inclusive the formation of siloxanes.

关键词： Global Reactions Model Silicon Rich-Oxide Defects LPCVD Luminescence

Role of capsule endoscopy in suspected celiac disease: A European multi-centre study

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World Journal of Gastroenterology 2017年第4期23卷 703-711页

作者： Marisol Luján-Sanchis Enrique Pérez-Cuadrado-Robles javier Garcia-Lledo José-francisco Juanmartinena Fernandez Luca Elli Victoria-Alejandra Jiménez-García Juan Egea-Valenzuela Julio Valle-Munoz Cristina Carretero-Ribón Ignacio Fernández-Urién-Sainz Antonio López-Higueras noelia Alonso-Lazaro Mileidis Sanjuan-Acosta francisco Sanchez-Ceballos Bruno Rosa Santiago González-Vázquez Federica Branchi Lucía Ruano-Díaz César Prieto-de-Frías Vicente Pons-Beltrán Pilar Borque-Barrera Begona González-Suárez Sofía Xavier Federico Argüelles-Arias Juan-Manuel Herrerías-Gutiérrez Enrique Pérez-Cuadrado-martínez javier Sempere-García-Argüelles Digestive Diseases Unit General University Hospital of Valencia Small Bowel Unit Hospital Morales Meseguer Digestive Diseases Unit General University Gregorio Maranón Unit of Gastroenterology and Endoscopy Complejo Hospitalario de Navarra Center for prevention and Diagnosis of Celiac Disease Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico Unit of Gastroenterology and Endoscopy University Hospital Virgen Macarena Gastroenterology department Hospital Virgen de la Arrixaca Department of Gastroenterology Complejo Hospitalario de Toledo Department of Gastroenterology University of Navarra Clinic1 Endoscopy Digestive Unit Digestive Diseases AreaUniversitari i Politècnic La Fe Hospital1 Digestive Diseases Unit University Hospital Nuestra Senora de Candelaria1 Digestive Diseases Unit Clinical Hospital San Carlos1 Digestive Diseases Unit Hospital da Senhora da Oliveira-Guimaraes1 Endoscopy Digestive Unit Hospital Clinic de Barcelona

AIMTo analyze the diagnostic yield (DY), therapeutic impact (TI) and safety of capsule endoscopy (CE).METHODSThis is a multi-centre, observational, analytical, retrospective study. A total of 163 patients with suspicion of celiac disease (CD) (mean age = 46.4 ± 17.3 years, 68.1% women) who underwent CE from 2003 to 2015 were included. Patients were divided into four groups: seronegative CD with atrophy (Group-I, n = 19), seropositive CD without atrophy (Group-II, n = 39), contraindication to gastroscopy (Group-III, n = 6), seronegative CD without atrophy, but with a compatible context (Group-IV, n = 99). DY, TI and the safety of CE were *** overall DY was 54% and the final diagnosis was villous atrophy (n = 65, 39.9%), complicated CD (n = 12, 7.4%) and other enteropathies (n = 11, 6.8%; 8 Crohn’s). DY for groups I to IV was 73.7%, 69.2%, 50% and 44.4%, respectively. Atrophy was located in duodenum in 24 cases (36.9%), diffuse in 19 (29.2%), jejunal in 11 (16.9%), and patchy in 10 cases (15.4%). Factors associated with a greater DY were positive serology (68.3% vs 49.2%, P = 0.034) and older age (P = 0.008). On the other hand, neither sex nor clinical presentation, family background, positive histology or HLA status were associated with DY. CE results changed the therapeutic approach in 71.8% of the cases. Atrophy was associated with a greater TI (92.3% vs 45.3%, P nd 81.9% of the patients responded to diet. There was one case of capsule retention (0.6%). Agreement between CE findings and subsequent histology was 100% for diagnosing normal/other conditions, 70% for suspected CD and 50% for complicated *** has a high DY in cases of suspicion of CD and it leads to changes in the clinical course of the disease. CE is safe procedure with a high degree of concordance with histology and it helps in the differential diagnosis of CD.

关键词： Capsule endoscopy Celiac disease Anti-transglutaminase antibodies Gluten-free diet non-celiac gluten sensitivity

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Kfz.385油罐车

模型世界 2018年第2期 79-81页

作者： francisco javier martínez Rodríguez

这款模型的板件是一款意大利(ITALERI)的老产品了(货号6467.1/35比例),但是适当的进行改造并添加细节后的效果依然非常不错。1我选用了Hauler出品的蚀刻片改件(货号HLU35038)来搭配这套板件。在组装前我先在蚀刻片表面上涂抹了一层AK15... 详细信息

这款模型的板件是一款意大利(ITALERI)的老产品了(货号6467.1/35比例),但是适当的进行改造并添加细节后的效果依然非常不错。1我选用了Hauler出品的蚀刻片改件(货号HLU35038)来搭配这套板件。在组装前我先在蚀刻片表面上涂抹了一层AK159金属锈蚀液,从而可以让蚀刻片表面变暗,并且让质感更像是真实的暗色钢制表面。我非常建议在使用任何蚀刻片时候都配合这款溶媒液,因为他同时还可以让漆在蚀刻片表面上有更好的附着力,同时粘贴起来也更方便。

关键词：油罐车油画颜料 Kfz.385 库尔斯克 AK

Determining the specific status of the Iberian sturgeons by means genetic analyses of old specimens

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Advances in Bioscience and Biotechnology 2010年第3期1卷 171-179页

作者： Francisca Robles Belén Cano-Roldán Carmelo Ruiz Rejón Luís javier martínez-González María Jesús álvarez-Cubero José Antonio Lorente José Antonio Riquelme Cantal Pedro Aguayo de Hoyos javier Carrasco Rus Miguel Cortés Sánchez María Dolores Simón vallejo Manuel Ruiz Rejón Roberto de la Herrán 不详

To clarify the species status of sturgeon from rivers of the Iberian Peninsula, eight molecular markers (4 nuclear and 4 mitochondrial) have been analysed in different specimens from historical museum samples and prehistoric samples from archaeological sites. These analyses indicate that one of these specimens (UGP captured in the Guadalquivir River in the 19th century) is A. sturio, based on all the eight molecular markers, four of them used from the first time in this study. In previous analyses based on 5 genetic markers, our group assigned two specimens captured in this river in the 1970-80s (EBD8173 and EBD8401) to the species A. naccarii, suggesting the presence of this species in the Iberian Peninsula. In this work, this conclusion is drawn after successfully obtaining a mitochondrial marker in a very old scute from a prehistoric site (Acinipo, about 1500 BC, from the Guadalquivir River basin). On the other hand, in the specimen EBD8174 captured in the Guadalquivir in 1975, we have obtained two new mitochondrial markers confirming that it can be considered A. sturio for all the mitochondrial markers, but nuclear ones identify it as A. naccarii. Finally, two very old samples (nerja E-VI and nerja n/62-63) were not successfully characterized by any molecular markers. Some aspects and consequences of our results are discussed, such as the origin of the “mosaic” specimen EBD8174 and, above all, the native status of A. naccarii in historic and prehistoric times in the southern Iberian Peninsula.

关键词： Iberian Sturgeons A. naccarii A. sturio Ancient DnA Genetic Identification Molecular Markers.

Coronary angiography findings in cardiac arrest patients with non-diagnostic post-resuscitation electrocardiogram:A comparison of shockable and non-shockable initial rhythms

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World Journal of Cardiology 2017年第8期9卷 702-709页

作者： Pedro martínez-Losas Pablo Salinas Carlos Ferrera María Teresa nogales-Romo francisco noriega María Del Trigo Iván javier núnez-Gil Luis nombela-Franco nieves Gonzalo Pilar Jiménez-Quevedo javier Escaned Antonio Fernández-Ortiz Carlos Macaya Ana Viana-Tejedor Interventional Cardiology and Coronary Care Unit Cardiovascular InstituteHospital Universitario Clínico San Carlos28040 MadridSpain

AIM To investigate the impact of coronary artery disease in a cohort of patients resuscitated from cardiac arrest with non-diagnostic *** From March 2004 to February 2016, 203 consecutive patients resuscitated from in or out-of-hospital sudden cardiac arrest and non-diagnostic post-resuscitation electrocardiogram(defined as ST segment elevation or pre-sumably new left bundle branch block) whounderwent invasive coronary angiogram during hospitalization were included. For purpose of analysis and comparison, patients were classified in two groups: Initial shockable rhythm(ventricular tachycardia or ventricular fibrillation; n = 148, 72.9%) and initial non-shockable rhythm(n = 55, 27.1%). Baseline characteristics, coronary angiogram findings including Syntax Score and long-term survival rates were compared. RESULTS Sudden cardiac arrest was witnessed in 95.2% of cases, 66.7% were out-of-hospital patients and 72.4% were male. There were no significant differences in baseline characteristics between groups except for higher mean age(68.1 years vs 61 years, P = 0.001) in the nonshockable rhythm group. Overall 5-year mortality of the resuscitated patients was 37.4%. Patients with non-shockable rhythms had higher mortality(60% vs 29.1%, P nd a worst neurological status at hospital discharge based on cerebral performance category score(CPC 1-2: 32.7% vs 53.4%, P = 0.02). Although there were no significant differences in global burden of coronary artery disease defined by Syntax Score(mean Syntax Score: 10.2 vs 10.3, P = 0.96) there was a trend towards a higher incidence of acute coronary lesions in patients with shockable rhythm(29.7% vs 16.4%, P = 0.054). There was also a higher need for ad-hoc percutaneous coronary intervention in this group(21.9% vs 9.1%, P = 0.03). COnCLUSIOn Initial shockable group of patients had a trend towards higher incidence of acute coronary lesions and higher need of ad-hoc percutaneous intervention vs nonshockable

关键词： Sudden cardiac arrest Electrocardiogram Invasive coronary angiography Percutaneous coronary intervention Syntax score Coronary artery disease

Conservative management of a recurrent puerperal uterine inversion with bakri<sup>®</sup>balloon tamponade

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Open Journal of Obstetrics and Gynecology 2011年第4期1卷 197-201页

作者： Jesús Joaquín Hijona Elósegui francisco javier Frutos Arenas Antonio Carballo García Juan Antonio López López Gabriel Castilla Peinado Peinado Juan Manuel Torres martí 不详

Puerperal Uterine Inversion (PUI) is a rare but potentially life-threatening delivery complication in which the uterine fundus collapses within the endometrial cavity. This “glove-finger” introflexion of uterine walls generally occurs as an immediate postpartum complication and is responsible of different degrees of vaginal bleeding, shock and hypogastric pain that can cause serious maternal complications, including death. There are few reports of recurrent postpartum uterine inversion like the one we present here, and its causes remain unclear. Early diagnosis of this complication is crucial as it is the only one measure that can allow a successful and conservative treatment: an inverse relationship between the time that uterus keeps inverted and the probability of repositioning has been firmly established. This case report describes the exceptional and innovative use of the SOS Bakri? balloon (Cook Medical Incorporated) in the management of a recurrent puerperal uterine inversion. To our knowledge it is one of the first reports in the world of this procedure, perhaps the second one after Soleymani’s et al description;and the first one in a third degree recurrent puerperal uterine inversion.

关键词： Balloon Tamponade Intrauterine Management Postpartum Haemorrhage Uterine Inversion Review Treatment

GOECP/SEOR radiotherapy guidelines for thymic epithelial tumours

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World Journal of Clinical Oncology 2021年第4期12卷 195-216页

作者： Mikel Rico Sonia Flamarique Cristina Casares Tamara García Miriam López Maribel martínez javier Serrano Manuel Blanco Raúl Hernanz Lourdes de Ingunza-Barón francisco JoséMarcos Felipe Couñago Department of Radiation Oncology Complejo Hospitalario de NavarraPamplona 31008NavarraSpain Health Research Institute of navarre(IdiSnA) Navarra BiomedPamplona 31008NavarraSpain Department of Radiation Oncology University Hospital Miguel ServetZaragoza 50009AragónSpain Department of Radiation Oncology University Hospital of CaceresCáceres 10004ExtremaduraSpain Department of Radiation Oncology Hospital Universitario de FuenlabradaFuenlabrada 28942MadridSpain Department of Radiation Oncology Hospital Clínico Universitario Lozano BlesaZaragoza 50009AragónSpain Department of Radiation Oncology Clínica Universidad de NavarraMadrid 28027Spain Department of Radiation Oncology Hospital Universitario TorrecárdenasAlmería 04009AndalucíaSpain Department of Radiation Oncology Hospital Universitario Ramón y CajalMadrid 28034Spain Department of Radiation Oncology Hospital Universitario Puerta del MarCádiz 11009AndalucíaSpain Department of Radiation Oncology Hospital Universitario Quirónsalud MadridHospital La LuzUniversidad Europea de MadridMadrid 28223Spain

Thymic epithelial tumours(TET)are rare,heterogeneous neoplasms that range from resectable indolent tumours to aggressive thymic carcinomas with a strong tendency to *** pathological diagnosis is complex,in part due to the management of TETs is scant and mainly based on non-randomised studies and retrospective ***,the clinical management of TETs tends to be highly heterogenous,which makes it difficult to improve the evidence *** role of technological advances in the field of radiotherapy and new systemic therapies in the treatment of TETs has received little attention to *** the present clinical guidelines,developed by the GOECP/SEOR,we review recent developments in the diagnosis and classification of *** also present a consensus-based therapeutic strategy for each disease stage that takes into consideration the best available *** guidelines focus primarily on the role of radiotherapy,including recent advances,in the management of *** main aim of this document is to promote the standardisation of clinical practice and lay the foundations for future studies to clarify the main unresolved questions related to the optimal management of TET.

关键词： Targeted therapies Thymic epithelial tumors Radiotherapy Reirradiation Guidelines Chemotherapy

F-Actin Distribution Changes Provoked by Acetaminophen in the Proximal Tubule in Kidney of Adult Male Rat

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Microscopy Research 2016年第3期4卷 39-45页

作者： Fernando Jaramillo-Juárez Jose Roberto Macías-Pérez Ma. Consolación martínez-Saldaña francisco javier Avelar-González Víctor Manuel Loera-Muro Edgar Eduardo Hernández-Cuéllar francisco Jaramillo Higinio Manuel González Reynaga Alma Lilian Guerrero-Barrera Departamento de Fisiologia y Farmacologia Centro de Ciencias Basicas Universidad Autonoma de Aguascalientes Aguascalientes Mexico Departamento de Morfologia Centro de Ciencias Basicas Universidad Autonoma de Aguascalientes Aguascalientes Mexico

Acetaminophen is a drug used to treat many conditions as headache, muscle aches, arthritis, backache, toothache, and fever between others, but collateral effects of this drug are not well known yet. Here is tested its effect on proximal tubule epithelium. Acetaminophen (APAP) at doses of 200, 500, 1000 and 1500 mg/Kg i.p. caused cell damage and changes in F-actin distribution in the proximal tubule of male Wistar rats. After 48 hours of treatment, the proximal tubule epithelium showed tumefaction and necrosis. Dose of 200 mg/kg decreased the F-actin and was observed a structure in patches in the basal cytoplasm of epithelial cells of the proximal tubule. This effect was increased depending on the administered dose. Dose of 1000 mg/kg produced the highest histological damage and changes in the actin cytoskeleton. Results of this study suggested that nephrotoxic damage produced by high doses of APAP included breakdown of cytoskeleton in proximal tubule epithelium.

关键词： Acetaminophen Cytoskeleton Proximal Tubule Kidney Damage

Characterization of a Collection of Brassica carinata Genotypes for in vitro Culture Response and Mode of Shoot Regeneration

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Opposing roles of plant laticifer cells in the resistance to insect herbivores and fungal pathogens

American Journal of Plant Sciences（美国植物学期刊） 2011年第1期

作者： javier Gil-Humanes Antonio martín francisco Barro

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Plant Communications 2021年第3期2卷 93-104页

作者： Lourdes Castelblanque javier García-Andrade Clara martínez-Arias Juan J.Rodríguez francisco J.Escaray Ernestina Aguilar-Fenollosa Josep A.Jaques Pablo Vera Instituto de Biología Moleculary Celular de Plantas Universitat Politécnica de Valéncia-C.S.I.CCiudad Politécnica de la InnovaciònEdificio 8EIngeniero Fausto Elios/n46022 ValenciaSpain Universitat Jaume I Departament de Ciéncies Agráries i del Medi NaturalCampus del Riu Sec12003 Castellòde la PlanaSpain

More than 12,000 plant species(ca.10%of flowering plants)exude latex when their tissues are *** is produced and stored in specialized cells named“laticifers”.Laticifers form a tubing system composed of rows of elongated cells that branch and create an internal network encompassing the entire *** constitute a recent evolutionary achievement in ecophysiological adaptation to specific natural environments;however,their fitness benefit to the plant still remains to be *** identification of Euphorbia lathyris mutants(pil mutants)deficient in laticifer cells or latex metabolism,and therefore compromised in latex production,allowed us to test the importance of laticifers in pest *** provided genetic evidence indicating that laticifers represent a cellular adaptation for an essential defense strategy to fend off arthropod herbivores with different feeding habits,such as Spodoptera exigua and Tetranychus *** marked contrast,we also discovered that a lack of laticifer cells causes complete resistance to the fungal pathogen Botrytis ***,a latex-derived factor required for conidia germination on the leaf surface was *** factor promoted disease susceptibility enhancement even in the non-latex-bearing plant *** speculate on the role of laticifers in the coevolutionary arms race between plants and their enemies.

关键词： latex Euphorbia lathyris disease resistance disease susceptibility plant defense