检索结果-南通市图书馆

Effects of SARS-CoV-2 infection on incidence and treatment strategies of hepatocellular carcinoma in people with chronic liver disease

在线全文

学校读者我要写书评

暂无评论

World Journal of Hepatology 2024年第2期16卷 211-228页

作者： Lung-Yi Mak Matthew Shing Hin Chung Xue Li francisco Tsz Tsun Lai Eric Yuk Fai Wan Celine Sze Ling Chui Franco Wing Tak Cheng Esther Wai Yin Chan Ching Lung Cheung Ivan Chi Ho Au Xi Xiong Wai-Kay Seto Man-Fung Yuen Carlos King Ho Wong Ian Chi Kei Wong Department of Medicine The University of Hong KongHong KongChina State Key Laboratory of Liver Research The University of Hong KongHong KongChina Department of Pharmacology and Pharmacy The University of Hong KongHong KongChina Laboratory of Data Discovery for Health(D24H) Hong Kong Science and Technology ParkHong KongChina Department of Family Medicine and Primary Care The University of Hong KongHong KongChina School of Nursing The University of Hong KongHong KongChina School of Public Health The University of Hong KongHong KongChina Research Department of Practice and Policy University College LondonLondon WC1E 6BTUnited Kingdom Aston School of Pharmacy Aston UniversityBirmingham B47ETUnited Kingdom

BACKGROUND Chronic liver disease(CLD)was associated with adverse clinical outcomes among people with severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)*** To determine the effects of SARS-CoV-2 infection on the incidence and treatment strategy of hepatocellular carcinoma(HCC)among patients with *** A retrospective,territory-wide cohort of CLD patients was identified from an electronic health database in Hong *** with confirmed SARS-CoV-2 infection[coronavirus disease 2019(COVID-19)+CLD]between January 1,2020 and October 25,2022 were identified and matched 1:1 by propensity-score with those without(COVID-19-CLD).Each patient was followed up until death,outcome event,or November 15,*** outcome was incidence of *** outcomes included all-cause mortality,adverse hepatic outcomes,and different treatment strategies to HCC(curative,non-curative treatment,and palliative care).Analyses were further stratified by acute(within 20 d)and post-acute(21 d or beyond)phases of SARS-CoV-2 *** rate ratios(IRRs)were estimated by Poisson regression *** Of 193589 CLD patients(>95%non-cirrhotic)in the cohort,55163 patients with COVID-19+CLD and 55163 patients with COVID-19-CLD were included after 1:1 propensity-score *** 249-d median follow-up,COVID-19+CLD was not associated with increased risk of incident HCC(IRR:1.19,95%CI:0.99-1.42,P=0.06),but higher risks of receiving palliative care for HCC(IRR:1.60,95%CI:1.46-1.75,P<0.001),compared to *** both acute and post-acute phases of infection,COVID-19+CLD were associated with increased risks of allcause mortality(acute:IRR:7.06,95%CI:5.78-8.63,P<0.001;post-acute:IRR:1.24,95%CI:1.14-1.36,P<0.001)and adverse hepatic outcomes(acute:IRR:1.98,95%CI:1.79-2.18,P<0.001;post-acute:IRR:1.24,95%CI:1.13-1.35,P<0.001),compared to *** Although CLD patients with SARS-CoV-2 infection were not associated with increased risk of HCC,they

关键词： SARS-CoV-2 infection Chronic liver disease Long COVID Post-COVID-19 syndrome Cirrhosis Hepatocellular carcinoma

Polygeneration Study of Low-to-Medium Enthalpy Geothermal Reservoirs in Mexico

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Thermal Science 2021年第3期30卷 1077-1087页

作者： CHÁVEZ Oscar GODÍNEZ francisco Tecnológico Nacional de México/I.T.Chihuahua.Av.Tecnológico 2909 C.P.31310ChihuahuaChihuahuaMéxico Instituto de Ingeniería Universidad Nacional Autónoma de MéxicoUNAMC.U.Ciudad de MéxicoC.P.04510México Polo Universitario de Tecnología Avanzada Universidad Nacional Autónoma de MéxicoVía de la Innovación No.410Autopista Monterrey-Aeropuertokm.10 PIITC.P.66629Apodaca Nuevo LeónMéxico

This study combines the thermodynamic analysis of a polygeneration system along with the numerical modelling of the thermal behavior of geothermal reservoirs in Mexico to exploit their *** reservoir was modeled as a porous medium assuming a five-spot well configuration and local thermal *** heat conduction-convection along with the Laplace equations were solved to compute temperature distributions,the useful life and the optimum distance between injection-extraction *** predicted temperature and pressure of the geothermal fluid at the outlet of the reservoir were exploited in the polygeneration system consisting of:(1)a Rankine cycle,(2)an absorption refrigeration cycle,and(3)a heat *** developed approach allows calculating both the optimal distance between injection-extraction wells and the global(utilization)efficiency of six arrangements(each composed by a reservoir connected to a polygeneration system)by assuming that reservoirs have a lifespan of 30 *** also show that:(a)due to the low efficiency of the Rankine cycle,very little thermal energy is converted into electrical one;(b)not only the temperature and the size are important when evaluating the power production performance of reservoirs,but also the permeability plays a fundamental role;(c)the first law efficiency of the polygeneration system ranges from 41.9%to 43.7%;(d)the utilization efficiency of the six arrangements lies in the range between 25.8%and 31%.

关键词： polygeneration system geothermal reservoir local thermal equilibrium low-to-medium enthalpy

Sex and habitat differences in size and coloration of an amphibian’s poison glands match differential predator pressures

在线全文

学校读者我要写书评

暂无评论

Integrative Zoology 2022年第5期17卷 764-776页

作者： francisco Javier ZAMORA-CAMACHO Department of Phisical Chemical and Natural SystemsPablo de Olavide UniversitySevilleSpain Department of Biodiversity Ecology and EvolutionComplutense University of MadridMadridSpain

Chemical defenses are frequently accompanied by salient color patterns actively avoided by predators,a phe-nomenon referred to as ***,the production of both chemical defenses and pigments is costly,and is thus expected to be reduced under mild predator *** this work,I compared the size and coloration of parotoid glands(2 dorsal,external swollen structures that secrete toxins in toads)of male and female Epidalea calamita toads from agrosystems and from pine groves.I also quantiﬁed the predator attacks received by plas-ticine toad models,whose“parotoid glands”differed in size and color conspicuousness,exposed in each *** avoided models with large and conspicuous parotoid glands,but models in agrosystems were more of-ten *** actual toads,agrosystem and male individuals had larger parotoid glands,presumably implying greater production of chemical defenses than in pine grove and female conspeciﬁ***ﬁndings are aligned with previous research suggesting that both agrosystem toads and males in this system are subjected to a more intense predator *** between parotoid gland and dorsum coloration was greater in agrosys-tem toads.A marked internal pattern could function as an aposematic signal,which could counteract increased predator pressure.

关键词： anuran agrosystem aposematism Epidalea calamita plasticine model

Impact of emulated inertia from wind power on under-frequency protection schemes of future power systems

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Modern Power Systems and Clean Energy 2016年第2期4卷 211-218页

作者： francisco Manuel GONZALEZ-LONGATT Loughborough University Loughborough LE652JGUK

Future power systems face several *** of them is the use of high power converters that decouple new energy sources from the AC power *** situation decreases the total system inertia affecting its ability to overcome system frequency *** wind power industry has created several controllers to enable inertial response on wind turbines generators:artificial,emulated,simulated,or synthetic *** paper deals with the issues related to the emulated inertia of wind turbines based on full-converters and their effect on the under-frequency protection schemes during the recovery period after system frequency disturbances *** main contribution of this paper is to demonstrate the recovery period of under-frequency transients in future power systems which integrate wind turbines with emulated inertia capability does not completely avoid the worse scenarios in terms of under-frequency load *** extra power delivered from a wind turbine during frequency disturbances can substantially reduce the rate of frequency *** it provides time for the active governors to respond.

关键词： Frequency controller Frequency stability Power system Protection scheme Wind turbine generator

Integrating time progression in ecoimmunology studies: beyond immune response intensity

在线全文

学校读者我要写书评

暂无评论

Current Zoology 2019年第2期65卷 205-212页

作者： francisco Javier ZAMORA-CAMACHO Department of Biological Sciences Dartmouth College Hanover New Hampshire USA Department of Biogeography and Global Change Museo Nacional de Ciencias Naturales (MNCN) Spanish National Research Council (CSIC) Madrid Spain

Habitat alterations in agroecosystems may damage amphibian immune capacity. As agroecosystem extension is increasing worldwide, broader-context knowledge on the effects of agroecosystem stressful conditions on amphibian immune capacity is crucial for understanding and management of amphibian global declines. However, most studies on ecoimmunology assume synchronal amonggroup immune-response peaks, and focus on immune response after standardized time lapses, neglecting its progress!on. Herein, I compared inflamatory response short-term progression of agro ecosystem and n atural-habitat female and male n atterjack toads Epi da lea calamita, by measuri ng swelling response, once per hour, 6 h following an artificial immune challenge with innocuous antigen phytohemagglutinin. I also compared maximum magnitude of swelling response, irrespective of the moment when it was reached. Habitat differences arose only 3 h after challenge, when naturalhabitat toads showed greater swelling response. Maximum magnitude of swelling response was similar in toads from both habitats. However, agroecosystem toads showed a delayed swelling response as compared with natural-habitat conspecifics, probably as a consequenee of agroecosystem stressful conditions. Such a delay suggests a weaker immune capacity, and consequently impaired anti-pathogen performance. Regarding sex, swelling response magnitude did not differ between males and females. Female swelling response peaked earlier, but that of males was more sustai ned in time, which con tradicts general across-taxa fin dings that males show impaired immune response. Interestingly, results suggest that measuring swelling response only after some standardized period following stimulation may be a simplistic approach and produce unrealistic results. Consequently, studies on ecoimmunology should implement swelling response progression in order to produce unbiased science.

关键词： agroecosystem amphibian immunocompetence natural habitat immune response progressi on

Changes in the sorption, desorption, distribution, and availability of copper, induced by application of sewage sludge on Chilean soils contaminated by mine tailings

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2012年第5期24卷 912-918页

作者： Tatiana Garrido Jorge Mendoza francisco Arriagada Faculty of Chemical Sciences and Pharmacy Department of Inorganic and Analytical Chemistry University of Chile

The effect of mine tailings and sewage sludge was evaluated on sorption, desorption, availability and distribution of copper in two soils, one high （sandy soil） and one low in copper （clay soil）. In both soils contaminated by mine tailings the copper sorption capacity and the affinity of the substrate for the metal decreased substantially compared to the uncontaminated soils, however, the sorption remained always high in the clay soil substrates. In the substrates with sandy soil, the high Cu content and lower clay content were determining factors in the lower magnitude of the sorption. Similarly, metal desorption was closely related to these two parameters, and it was higher in clay soil with lower pH. In general, the application of sewage sludge favored the sorption of Cu in soils contaminated and uncontaminated with mine tailings, and in all cases desorption decreased, an effect that remained for at least 30 days. Simple extraction of Cu with CaCl2 and diethylenetriaminepentaacetic acid gave contradictory results, so a careful choice of the procedure is required, depending on the level of metal in the soil and on the acting principle of the extracting agent. In that relation, more complete information on the changes in the metal forms was obtained by application of the sequential extraction procedure proposed by the European Community Bureau of Reference.

关键词： sewage sludge copper sorption mine tailings copper desorption European Community Bureau of Reference sequential extraction

Ecophysiology of egg rejection in hosts of avian brood parasites:new insights and perspectives

在线全文

学校读者我要写书评

暂无评论

Current Zoology 2021年第6期67卷 631-638页

作者： francisco RUIZ-RAYA Centro de Investigación Marina Universidade de VigoGEAVigo 36310Spain

Egg rejection is the most effective and widespread defense used by host species to counteract the extreme fitness costs frequently imposed by obligate avian brood ***,the proximate mechanisms underlying between-and within-individual variation in host responses remain poorly *** evidence suggests that egg rejection is dependent on individual physiological states,and draws attention to the role of hormones as mediators of flexible antiparasitic *** this perspective article,I outline recent advances in our understanding of the proximate factors that mediate egg rejection.I also point out some areas where knowledge remains still lacking,especially those related to the development and maintenance of effective cognitive functions,the potential role of oxidative stress,immunological state,and developmental stressors.I propose new hypotheses that stimulate future research on behavioral host responses toward brood parasitism.

关键词： cognitive performance condition-dependence corticosterone flexible responses prolactin

Hydrolysis of Urea to Produce Ammonia Dircio francisco Xavier Fatima Ximenes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hydrolysis of Urea to Produce Ammonia Dircio Francisco Xavie...

作者： Dircio francisco Xavier Fatima Ximenes（弗朗西斯科）华东理工大学

学位级别：硕士

氮氧化物（NOx）引起了巨大的环境问题,是目前世界上最大的环境污染物之一,随着对NOx法规的逐步收紧,世界各国都在积极开展减少NOx污染的研究。目前已开发利用了多种技术,其中选择性催化还原（SCR）和选择性非催化还原（SNCR）具有较高... 详细信息

氮氧化物（NOx）引起了巨大的环境问题,是目前世界上最大的环境污染物之一,随着对NOx法规的逐步收紧,世界各国都在积极开展减少NOx污染的研究。目前已开发利用了多种技术,其中选择性催化还原（SCR）和选择性非催化还原（SNCR）具有较高的脱硝效率。在SCR和SNCR工艺中,还原剂被注入烟气中,将NOx还原为无害氮（N2）。目前最常用的还原剂是氨（NH3）。尿素催化水解制氨在氨基脱氮过程中起着重要作用。本论文的目标有三个。首先,对尿素水解的催化剂进行筛选,其中均相催化剂表现出了良好的性能,因此本文用选择该类催化剂来进行尿素催化水解反应,然后尿素水解的转化率采用滴定法来进行分析。第二是设计了四因素,三水平Box-Behnken实验,结合响应面法对工艺条件进行优化,研究反应温度,反应时间,反应压力和催化剂用量对尿素水解制氨的影响及其交互作用。建立了尿素水解率的相关模型。第三是采用物料平衡方程,热量平衡方程,化学平衡方程及相平衡方程组成的非线性方程组来构建开口体系内尿素水解过程的热力学模型和动力学模型,并引入修正的Lewis-Randall方程和修正的Herry方程来描述水解反应器内NH3-CO2-H2O-（NH2）2CO（ACWU）四元多自由度气液平衡关系,气液两相的非理想性则分解采用PR状态方程和扩展UNIQUAC模型进行修正。结果表明,采用催化活性较好的乙酸钠（7g）催化剂对工艺条件进行优化,响应面法最优化的合成条件为;反应温度160℃,反应时间4h,反应压力0.4MPa和催化剂用量0.034wt%,在此工艺条件下尿素水解的转化率为98.620%,同时建立了尿素水解制氨的二次数学模型,该模型对实验结果有良好的预测作用。

关键词：尿素水解制氨热力学动力学

Splenic rupture following colonoscopy

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2008年第41期14卷 6410-6412页

作者： Juan francisco Guerra Ignacio San francisco Fernando Pimentel Luis Ibanez Departamento de Cirugía Digestiva Pontificia Universidad Católica de Chile Marcoleta 367

Colonoscopy is a safe and routinely performed diagnostic and therapeutic procedure for different colorectal diseases. Although the most common complications are bleeding and perforation, extracolonic or visceral injuries have also been described. Splenic rupture is a rare complication following colonoscopy, with few cases reported. We report a 60-year-old female who presented to surgical consultation 8 h after a diagnostic colonoscopy. Clinical, laboratory and imaging findings were suggestive for a massive hemoperitoneum. At surgery, an almost complete splenic disruption was evident, and an urgent splenectomy was performed. After an uneventful postoperative period, she was discharged home. Splenic injury following colonoscopy is considered infrequent. Direct trauma and excessive traction of the splenocolic ligament can explain the occurrence of this complication. Many times the diagnosis is delayed because the symptoms are due to colonic insuffl ation, so the most frequent treatment is an urgent splenectomy. A high index of suspicion needs an early diagnosis and adequate therapy.

关键词： Colonoscopy Splenic injury Splenic rupture Splenectomy