检索结果-南通市图书馆

PillCam COLON 2~ in Crohn's disease:A new concept of pan-enteric mucosal healing assessment

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2015年第23期21卷 7233-7241页

作者： Pedro Boal Carvalho Bruno Rosa francisca dias de castro Maria Joo Moreira José Cotter Life and Health Sciences Research Institute School of Health Sciences University of Minho ICVS/3B’s PT Government Associate Laboratory Gastroenterology department Centro Hospitalar do Alto Ave

AIM: To evaluate mucosal healing in patients with small bowel plus colonic Crohn's disease(CD) with a single non-invasive examination, by using PillCam COLON 2.(PCC2).METHODS: Patients with non-stricturing nonpenetrating small bowel plus colonic CD in sustained corticosteroid-free remission were included. At diagnosis,patients had undergone ileocolonoscopy to identify active CD lesions, such as ulcers and erosions, and small bowel capsule endoscopy to assess the Lewis Score(LS). After ≥ 1 year of follow-up, patients underwent entire gastrointestinal tract evaluation with PCC2. The primary endpoint was assessment of CD mucosal healing, defined as no active colonic CD lesions and LS ded(7 male;mean age: 32 years), and mean follow-up was 38 *** majority of patients(83.3%) received immunosuppressive therapy. Three patients(25%) achieved mucosal healing in both the small bowel and the colon,while disease activity was limited to either the small bowel or the colon in 5 patients(42%). It was possible to observe the entire gastrointestinal tract in 10 of the12 patients(83%) who underwent ***: Only three patients in sustainedcorticosteroid-free clinical remission achieved mucosal healing in both the small bowel and the colon, highlighting the limitations of clinical assessment when stratifying disease activity, and the need for pan-enteric endoscopy to guide therapeutic modification.

关键词： Crohn's disease Mucosal healing Capsuleendoscopy Small bowel diseases Inflammatory boweldisease

Essential role of small bowel capsule endoscopy in reclassification of colonic inflammatory bowel disease type unclassified

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Endoscopy 2017年第1期9卷 34-40页

作者： Sara Monteiro francisca dias de castro Pedro Boal Carvalho Bruno Rosa Maria Joao Moreira Rolando Pinho Miguel Mascarenhas Saraiva José Cotter department of Gastroenterology Hospital da Senhora da Oliveira-Guimaraes ManopH-Endo-scopy and Digestive Motility Laboratory Portugal and CUF Institute School of Medicine University of Minho ICVS/3B’s PT Government Associate Laboratory

AIM To evaluate the role of small bowel capsule endoscopy(SBCE) on the reclassification of colonic inflammatory bowel disease type unclassified(IBDU).METHODS We performed a multicenter, retrospective study including patients with IBDU undergoing SBCE, between 2002 and 2014. SBCE studies were reviewed and the inflammatory activity was evaluated by determining the Lewis score(LS). Inflammatory activity was considered significant and consistent with Crohn's disease(CD) when the LS ≥ 135. The definitive diagnosis during follow-up(minimum 12 mo following SBCE) was based on the combination of clinical, analytical, imaging, endoscopic and histological *** Thirty-six patients were included, 21 females(58%) with mean age at diagnosis of 33 ± 13(15-64) years. The mean follow-up time after the SBCE was 52 ± 41(12-156) mo. The SBCE revealed findings consistent with significant inflammatory activity in the small bowel(LS ≥ 135) in 9 patients(25%); in all of them the diagnosis of CD was confirmed during follow-up. In 27 patients(75%), the SBCE revealed no significant inflammatory activity(LS < 135); among these patients, the diagnosis of Ulcerative Colitis(UC) was established in 16 cases(59.3%), CD in 1 case(3.7%) and 10 patients(37%) maintained a diagnosis of IBDU during follow-up. A LS ≥ 135 at SBCE had a sensitivity = 90%, specificity = 100%, positive predictive value = 100% and negative predictive value = 94% for the diagnosis of *** SBCE proved to be fundamental in the reclassification of patients with IBDU. Absence of significant inflammatory activity in the small intestine allowed exclusion of CD in 94% of cases.

关键词： Inflammatory bowel disease Inflammatory bowel disease type unclassified Capsule endoscopy Crohn’s disease Lewis score Reclassification

Seasonal variation and host sex affect bat–bat fly interaction networks in the Amazonian savannahs

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Integrative Zoology 2024年第3期19卷 400-416页

作者： Paulo MEJIA Gustavo Lima URBIETA Bruna da Silva XAVIER IsaíJorge de castro JoséJúlio de TOLEDO Gustavo GRACIOLLI Lucio AndréVIANA dias William Douglas CARVALHO Programa de Pós-Graduação em Biodiversidade Tropical Universidade Federal do Amapá(UNIFAP)MacapáAPBrazil Programa de Pós-Graduação em Ecologia Instituto de BiologiaCentro de Ciências da SaúdeUniversidade Federal do Rio de Janeiro(UFRJ)Rio de JaneiroRJBrazil Laboratório de Mamíferos Instituto de Pesquisas Científicas e Tecnológicas do Estado do Amapá(IEPA)MacapáAPBrazil Programa de Pós-Graduação em Biologia Animal Laboratório de SistemáticaEcologia e Evolução(LSEE)Instituto de BiociênciasUniversidade Federal de Mato Grosso do Sul(UFMS)Campo GrandeMTBrazil Terrestrial Ecology Group(TEG-UAM) Departamento de EcologíaFacultad de CienciasUniversidad Autónoma de MadridMadridSpain Centro de Investigación en Biodiversidad y Cambio Global(CIBC-UAM) Universidad Autónoma de MadridMadridSpain

Bats are the second-most diverse group of mammals in the world,and bat flies are their main ***,significant knowledge gaps remain regarding these antagonistic interactions,especially since diverse factors such as seasonality and host sex can affect their network ***,we explore the influence of such factors by comparing species richness and composition of bat flies on host bats,as well as specialization and modularity of bat–bat fly interaction networks between seasons and adult host *** captured bats and collected their ectoparasitic flies at 10 sampling sites in the savannahs of AmapáState,northeastern region of the Brazilian *** female bats being more parasitized and recording greater bat fly species richness in the wet season,neither relationship was statistically *** pooled network could be divided into 15 compartments with 54 links,and all subnetworks comprised>12 *** total number of links ranged from 27 to 48(for the dry and wet seasons,respectively),and female and male subnetworks had 44 and 41 links,*** values were very low for the pooled network and for all *** results revealed higher bat fly species richness and abundance in the wet season,whereas specialization and modularity were higher in the dry ***,the subnetwork for female bats displayed higher specialization and modularity than the male ***,both seasonality and host sex contribute in different ways to bat–bat fly network *** studies should consider these factors when evaluating bat–bat fly interaction networks.

关键词： Amapá Amazon biome bat flies bats interaction networks

Synthesis of coral-like structures of Pr-Yb co-doped YIG: Structural,optical, magnetic and antimicrobial properties

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Rare Earths 2024年第3期42卷 543-554,I0004页

作者： A.Fernandez francisca P.Araujo Y.Guerra S.castro-Lopes J.Matilla-Arias Idglan S.de Lima Edson C.Silva-Filho Josy A.Osajima F.Guerrero R.Pena-Garcia Federal University of Piau Graduate Program in Materials Science and EngineeringTeresinaPIBrazil Federal Rural University of Pernambuco Academic Unit of Cabo de Santo AgostinhoCabo de Santo AgostinhoPEBrazil Federal University of Piaui Department of PhysicTeresinaPBrazil Federal University of Pernambuco Graduate Program in Materials ScienceRecifePEBrazil University of Granma Departmentof Basic Sciences and Applied InformaticsFaculty of Technical SciencesBayamoCuba Federal University of Amazonas Department of PhysicManausAMBrazil Federal University of Pernambuco Department of PhysicRecifePEBrazil

Coral-like structures of the Y_(3-x)Pr_(x)Fe_(5-y)Yb_(y)O_(12),(0.00 ≤ x ≤ 0.04, 0.00 ≤ y ≤ 0.02) compound were synthesized using the sol-gel method. Structural investigation certified the YIG cubic crystal structure formation, without any secondary phase. It is shown that, the relatively large ionic radius of the dopant cations results in an expansion of the lattice parameter, variations in the Iona-O-Iondangle, Iona-O,Iond-O and Ionc-O bond distances and decrease in the average crystallite size. Fourier transform infrared(FTIR) and Raman measurements are essential to testify the single-phase formation of YIG crystal structure and are observed changes in the stretching and vibrational modes, respectively. The morphological study, energy dispersive spectroscopy(EDS) spectra and textural properties show corallike structures, peaks associated with Pr^(3+) and Yb^(3+) atoms and the effect of dopants on surface area,diameter, and pore volume, respectively. The optical analysis from diffuse reflectance spectra witnessed an increase in the optical gap band, a decrease in Urbach energy and blue shift in the charge transfer,correlated with the expansion of the unit cell due to the dopant's insertion in the YIG structure. A typical ferrimagnetic behavior is exhibited by the Y_(3-x)Pr_(x)Fe_(5-y)Yb_(y)O_(12)compound. The saturation magnetization(M_(s)), cubic anisotropy constant(K_(1)) and coercive field(H_(c)) increase with the Pr^(3+)cations content, as consequence of their magnetic nature and distribution around of Fe^(3+)ions due to the coexistence with the Yb^(3+). Finally, for the first time, antibacterial tests by mean of the direct contact method were performed for YIG co-doped with Pr^(3+)and Yb^(3+)and it is shown that, relatively high dosages of Pr^(3+) cations favored the activity against S. aureus, therefore, a new biological property for YIG doped with rare earths is presented.

关键词： Yttrium iron garnet(YIG) Coral-like structures Rare earths Band gap energy Magnetic properties Antimicrobial properties

Finding the solution for incomplete small bowel capsule endoscopy

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Endoscopy 2013年第12期5卷 595-599页

作者： José Cotter francisca dias de castro Joana Magalhes Maria Joo Moreira Bruno Rosa Gastroenterology department Centro Hospitalar do Alto Ave Life and Health Sciences Research Institute (ICVS) School of Health Sciences University of Minho ICVS/3B’s PT Government Associate Laboratory

AIM:To evaluate whether the use of real time viewer(RTV)and administration of domperidone to patients with delayed gastric passage of the capsule could reduce the rate of incomplete examinations(IE)and improve the diagnostic yield of small bowel capsule endoscopy(SBCE).METHODS:Prospective single center interventional study,from June 2012 to February *** location was systematically checked one hour after ingestion using *** it remained in the stomach,the patient received 10 mg domperidone per os and the location of the capsule was rechecked after 30 *** the capsule remained in the stomach a second dose of10 mg of domperidone was administered *** another 30 min the position was rechecked and if the capsule remained in the stomach,it was passed into the duodenum by upper gastrointestinal(GI)*** rate of IE and diagnostic yield of SBCE were compared with those of examinations performed before the use of RTV or domperidone in our department(control group,January 2009-May 2012).RESULTS:Both groups were similar regarding age,sex,indication,inpatient status and surgical *** control group included 307 patients,with 48(15.6%)*** RTV group included 82 patients,with3(3.7%)IE,P=*** the control group,average gastric time was significantly longer in patients with IE than in patients with complete examination of the small bowel(77 min vs 26 min,P=0.003).In the RTV group,the capsule remained in the stomach one hour after ingestion in 14/82 patients(17.0%)vs 48/307(15.6%)in the control group,P=*** did not significantly affect small bowel transit time(260min vs 297 min,P=0.229).The capsule detected positive findings in 39%of patients in the control group and 49%in the RTV group(P=0.081).CONCLUSION:The use of RTV and selective administration of domperidone to patients with delayed gastric passage of the capsule significantly reduces incomplete examinations,with no effect on small bowel transit time or diagnostic yield.

关键词： Small bowel capsule endoscopy Prokinetic drugs Domperidone Incomplete examination

PillCam~ SB3 capsule: Does the increased frame rate eliminate the risk of missing lesions?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2016年第10期22卷 3066-3068页

作者： Sara Monteiro francisca dias de castro Pedro Boal Carvalho Maria Joao Moreira Bruno Rosa José Cotter department of Gastroenterology Hospital Senhora da Oliveira Rua dos Cutileiros Creixomil 4835-044 Guimaraes Portugal Life and Health Sciences Research Institute (ICVS) School of Health Sciences University of Minho 4710-057 Braga Portugal ICVS/3B's PT Government Associate Laboratory 4710-057 Braga/Guimaraes Portugal

Since its emergence in 2000, small bowel capsule endoscopy(SBCE) has assumed a pivotal role as an investigation method for small bowel diseases. The PillCam SB2-ex offers 12 h of battery time, 4 more than the previous version(SB2). Rahman et al recently found that the PillCam SB2-ex has a significantly increased completion rate, although without higher diagnostic yield, compared with the SB2. We would like to discuss these somewhat surprising results and the new potentialities of the PillCam SB3 regarding the diagnostic yield of small bowel studies. PillCam SB3 offers improved image resolution and faster adaptable frame rate over previous versions of SBCE. We recently compared the major duodenal papilla detection rate obtained with PillCam SB3 and SB2 as a surrogate indicator of diagnostic yield in the proximal small bowel. The PillCam SB3 had a significantly higher major duodenal papilla detection rate than the PillCam SB2(42.7% vs 24%, P = 0.015). Thus, the most recent version of the PillCam capsule, SB3, may increase diagnostic yield, particularly in the proximal segments of the small bowel.

关键词： PillCam~ SB2 PillCam~ SB3 Capsule endoscopy Diagnostic yield Lesions Frames

Virtual chromoendoscopy in small bowel capsule endoscopy: New light or a cast of shadow?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Endoscopy 2014年第8期6卷 359-365页

作者： José Cotter Joana Magalh es francisca dias de castro Mara Barbosa Pedro Boal Carvalho Sílvia Leite Maria Jo o Moreira Bruno Rosa Gastroenterology department Centro Hospitalar do Alto Ave 4835-044 Guimar es Portugal Life and Health Sciences Research Institute (ICVS) School of Health Sciences University of Minho 4710-057 Bra-ga Portugal ICVS/3B’s PT Government Associate Laboratory 4710-057 Braga/Guimar es Portugal

AIM: To evaluate whether virtual chromoendoscopy can improve the delineation of small bowel lesions previously detected by conventional white light small bowel capsule endoscopy(SBCE). METHODS: Retrospective single center study. One hundred lesions selected from forty-nine consecutive conventional white light SBCE(SBCE-WL) examinations were included. Lesions were reviewed at three Flexible Spectral Imaging Color Enhancement(FICE) settings and Blue Filter(BF) by two gastroenterologists with ex-perience in SBCE, blinded to each other's findings, whoranked the quality of delineation as better, equivalent or worse than conventional SBCE-WL. Inter-observer percentage of agreement was determined and analyzed with Fleiss Kappa(k) coefficient. Lesions selected for the study included angioectasias(n = 39), ulcers/ero-sions(n = 49) and villous edema/atrophy(n = 12). RESULTS: Overall, the delineation of lesions was im-proved in 77% of cases with FICE 1, 74% with FICE 2, 41% with FICE 3 and 39% with the BF, with a percent-age of agreement between investigators of 89%(k = 0.833), 85%(k = 0.764), 66%(k = 0.486) and 79%(k = 0.593), respectively. FICE 1 improved the delineation of 97.4% of angioectasias, 63.3% of ulcers/erosions and 66.7% of villous edema/atrophy with a percentage of agreement of 97.4%(k = 0.910), 81.6%(k = 0.714) and 91.7%(k = 0.815), respectively. FICE 2 improved the delineation of 97.4% of angioectasias, 57.1% of ulcers/erosions and 66.7% of villous edema/atrophy, with a percentage of agreement of 89.7%(k = 0.802), 79,6%(k = 0.703) and 91.7%(k = 0.815), respectively. FICE 3 improved the delineation of 46.2% of angioecta-sias, 24.5% of ulcers/erosions and none of the cases of villous edema/atrophy, with a percentage of agreement of 53.8% [k = not available(NA)], 75.5%(k = NA) and 66.7%(k = 0.304), respectively. The BF improved the delineation of 15.4% of angioectasias, 61.2% of ulcers/erosions and 25% of villous edema/atrophy, with a per-centage of agreement of 7

关键词： Capsule endoscopy Virtual chromoendoscopy Small bowel enteroscopy Flexible Spectral Imaging Color Enhancement Endoscopy Imaging review

Latent tuberculosis:Risk factors,screening and treatment in liver transplantation recipients from an endemic area

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Transplantation 2021年第12期11卷 512-522页

作者： Isabela dias Lauar Luciana Costa Faria Roberta Maia de castro Romanelli Wanessa Trindade Clemente Medicine department Universidade Josédo Rosário VellanoBelo Horizonte 31710030Minas GeraisBrazil Internal Medicine department Faculdade de MedicinaUniversidade Federal de Minas Gerais(UFMG)Belo Horizonte 30130100Minas GeraisBrazil Pediatrics department Faculdade de MedicinaUniversidade Federal de Minas Gerais(UFMG)Belo Horizonte 30130100Minas GeraisBrazil department of Laboratory Medicine Faculdade de MedicinaUniversidade Federal de Minas Gerais(UFMG)Belo Horizonte 30130100Minas GeraisBrazil

BACKGROUND Patients undergoing solid organ transplantation,particularly those who live or have lived in tuberculosis(TB)endemic areas,are at a high risk of developing *** majority of post-transplantation TB cases are associated with reactivation of latent TB infection(LTBI).Brazil is in a single position with overlapping areas of high TB endemicity and high transplant *** liver transplant(LT),one should be aware of the potential hepatotoxicity associated with the treatment regimens for *** To evaluate the frequency of LTBI in LT patients and treatment-related *** This was a retrospective analysis of a cohort of cirrhotic patients aged≥18 years,who underwent LT at a high-complexity teaching hospital from January 2005 to december *** Overall,429 patients underwent LT during the study *** these,213(49.7%)underwent the tuberculin skin test(TST)during the pre-transplant period,and 35(16.4%)of them had a positive *** treatment for LTBI was initiated after LT in 12(34.3%)of the TST-positive patients;in 3(25.0%),treatment was maintained for at least 6 *** The prevalence of LTBI was lower than *** and completion of LTBI treatment was limited by difficulties in the management of these special patients.

关键词： Latent tuberculosis Liver transplantation Tuberculosis Infection Transplantation Risk factors

Protection status as determinant of carbon stock drivers in Cerrado sensu stricto

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Plant Ecology 2020年第3期13卷 361-368页

作者： Kelly Marianne Guimarães Pereira Natielle Gomes Cordeiro Marcela de castro Nunes Santos Terra Marcela Venelli Pyles Christian dias Cabacinha JoséMárcio de Mello Eduardo van den Berg department of Biology Federal University of LavrasCampus UniversitárioCEP 37200-000LavrasMinas Gerais stateBrazil department of Forest Sciences Federal University of LavrasCampus UniversitárioCEP 37200-000LavrasMinas Gerais stateBrazil department of Forest Sciences Institute of Agrarian SciencesFederal University of Minas GeraisCampus Regional de Montes ClarosCEP 39.404-547Montes ClarosMinas Gerais stateBrazil

Aims Natural vegetation plays an important role in global carbon cycling and ***,the Cerrado(Brazilian savannah)is considered a carbon sink because of its intrinsic *** aim was to evaluate how the aboveground biomass and biodiversity relationship change between three Cerrado remnants with different protection status:a‘control area’(Legal Reserve area),a protected area(PA)and a non-protected area(Non-PA).Methods All three studied fragments are situated in northern Minas Gerais state,*** estimated the aboveground carbon stocks based on the forest *** also measured three dimensions of biodiversity metrics for each plot:functional trait dominance,taxonomic diversity and functional *** following functional traits were evaluated for the species:wood density,maximum diameter and seed *** carried out generalized linear models seeking to evaluate how carbon stocks,community-weighted mean(CWM)trait values,species richness and diversity,and functional diversity indices differ among the *** Findings The Cerrado areas without protection status had lower carbon stocks,species richness,species diversity,functional richness and functional dispersion,whereas both PA and Non-PA had lower CWM maximum diameter and seed size compared with the Legal Reserve control *** linear models showed that carbon stocks,species and functional richness metrics were correlated within and across sites,and thus,species richness could serve as a good proxy for functional richness and carbon *** carbon stocks were positively driven by species richness and CWM maximum diameter,while they were negatively driven by functional *** richness,species diversity and CWM seed size appeared in the set of best models,but with no significant direct effect on carbon ***,we concluded that absence of protection in the Cerrado areas decreases both species richness and carbon stocks.

关键词： functional traits biodiversity biomass storage Brazilian Savanna human impacts