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Food and Nutrition Sciences 2015年第10期6卷 869-874页

作者： Jaime Paiva Lopes Aguiar francisca das chagas do amaral souza Coordination Society Environment and Health—CSAS National Institute for Amazonian Research—INPA Manaus Brazil

Camu-camu (Myrciaria dubia (H.B.K.) Mc Vaugh) is a fruit native to the Amazon region and is considered the greatest natural source of vitamin C worldwide. It is also a promising source of many phenolic compounds, including flavonoids and anthocyanins. Given the growing rates of chronic non-communicable diseases such as dyslipidemia, obesity and diabetesworldwide, freeze-dried camu-camu can be used for its functional properties, which can reduce the incidence of these diseases. Hence, the objective of this study was to produce freeze-dried camu-camu pulp and present it as an alternative functional food because of its high production and use potential, adding value to this fruit in particular, not very demanded by the food industry. Freeze-dried camu-camu pulp is a pink, homogeneous powder with great antioxidant capacity, 52,000 μmol TE/g, six times greater than freeze-dried acai powder. It is also very rich in vitamin C (20.31 g/100g), potassium (796.99 mg/100g), carbohydrates (47.00 g/100g), dietary fiber (19.23 g/100 g), many amino acids, other vitamins, and anthocyanins (0.739 mg/g). The camu-camu freeze-drying process is an effective alternative way to preserve the fruit, preserving its macronutrient and vitamin C contents. Camu-camu is also an excellent source of other bioactive compounds, such as minerals and other phenolic compounds. In conclusion, camu-camu can be used to introduce bioactive compounds into food products and to delay or prevent many human diseases.

关键词： Functional Foods Ascorbic Acid Freeze Drying Antioxidant Capacity

Camu-Camu (<i>Myrciaria dubia</i>HBK): Yogurt Processing, Formulation, and Sensory Assessment

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American Journal of Analytical Chemistry 2015年第5期6卷 377-381页

作者： Jaime Paiva Lopes Aguiar francisca das chagas do amaral souza Coordination Society Environment and Health—CSAS National Institute for Amazonian Research—INPA Manaus Brazil

The objective of this study is to formulate and assess technologies for producing yogurt with camu-camu pulp, which has market potential and can be included in school meals, providing the general population with a nutritious and functional product. Three formulations of yogurt with camu-camu pulp were prepared, F1 10%, F2 13%, and F3 15%, with the following ingredients: whole UHT (Ultra High Temperature) milk, camu-camu pulp, dairy culture, and sugar. The micro-biological characteristics of the final products were within the standards recommended by ANVISA. Regarding sensory assessment, formulation 1 achieved the highest acceptability. The chemical, physical, and microbiological parameters were within the limits established by the legislation, and the acceptability of the formulation containing 10% camu-camu pulp was satisfactory. This is a more quality food option for the Amazonian and Brazilian population.

关键词： Amazonian Fruit Sensory Analysis Processing Formulation Yogurt

Soluble and Insoluble Fiber in Some Amazonian Fruits with Low Energy Density

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Food and Nutrition Sciences 2014年第14期5卷 1415-1419页

作者： Jaime Paiva Lopes Aguiar francisca das chagas do amaral souza Coordination Society Environment and Health—CSAS National Institute for Amazonian Research—INPA Manaus Brazil

Fruits are unarguably one of the main sources of dietary fiber, but are regional Amazonian fruits sources of dietary fiber? The objective of the present study was to assess the nutritional characteristics and fiber contents of fresh fruits with low energy density. The study fruits wereabiu, bacuri, carambola, ingá-cipó, mapati, and taperebá acquired from the National Institute for Amazonian Research (INPA) and collected along kilometers 08 and 60 of highway BR174, AM-Brasil. Ash, protein, lipid, carbohydrate, energy and fiber contents were determined three times. The six fruits have very small and significantly different protein contents (p < 0.05). Taperebá and mapati presented the highest (4.65 g) and lowest (0.84 g) fiber contents, respectively. Except for abiu (0.49 g), the low lipid contents of the study fruits confirmed their low energy density. The soluble fiber content of the fruits was generally low, being highest in taperebá (1.51 g). The insoluble fiber fraction prevailed in all six study fruits, with taperebá and mapati presenting the highest (3.14 g) and lowest (0.65 g) insoluble fiber contents, respectively. The dietary fiber contents show that the study fruits can contribute to the composition of diets with appropriate dietary fiber contents and low energy densities.

关键词： Dietary Fiber Regional Fruits Proximate Composition

Plant growth and metabolism of exotic and native Crotalaria species for mine land rehabilitation in the Amazon

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Journal of Forestry Research 2024年第1期35卷 143-154页

作者： Hemelyn Soares das chagas Rafael Silva Guedes Markus Gastauer Paula Godinho Ribeiro Allan Klynger da Silva Lobato Cecílio Frois Caldeira Fabrício William deÁvila AndréRodrigues dos Reis Silvio Junio Ramos Instituto Tecnológico Vale Rua Boaventura da Silva955BelémPA 66055-090Brazil Universidade Federal do Sul e Sudeste do Pará XinguaraPABrazil Núcleo de Pesquisa Vegetal Básica e Aplicada Universidade Federal Rural da AmazôniaParagominasPABrazil Departamento de Engenharia Florestal Universidade Estadual do Centro-Oeste/UNICENTROIratiPRBrazil School of Sciences and Engineering São Paulo State University(UNESP)TupãSP.CEP 17602-496Brazil

Despite its enormous benefits,mining is respon-sible for intense changes to vegetation and soil ***,after extraction,it is necessary to rehabilitate the mined areas,creating better conditions for the establishment of plant species which is *** study evaluated mineral and organic fertilization on the growth,and carbon and nitrogen(N)metabolism of two Crotalaria species[Cro-talaria spectabilis(exotic species)and Crotalaria maypu-rensis(native species from Carajás Mineral Province(CMP)]established on a waste pile from an iron mine in CMP.A control(without fertilizer application)and six fertilization mixtures were tested(i=NPK;ii=NPK+micronutrients;iii=NPK+micronutrients+organic compost;iv=PK;v=PK+micronutrients;vi=PK+micronutrients+organic compost).Fertilization contributed to increased growth of both species,and treatments with NPK and micronutrients had the best results(up to 257%***),while organic fertilization did not show *** Crotalaria had a greater number of nodules,higher nodule dry mass,chlorophyll a and b contents and showed free ammonium as the predominant N form,reflecting greater increments in biomass compared to native *** having lower growth,the use of this native species in the rehabilitation of mining areas should be considered,mainly because it has good development and meets current government legislation as an opportunity to restore local biodiversity.

关键词： Biological nitrogen fixation Mining Nitrogen metabolism Plant nutrition

Automatic Detection of COVID-19 Infection Using Chest X-Ray Images Through Transfer Learning

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IEEE/CAA Journal of Automatica Sinica 2021年第1期8卷 239-248页

作者： Elene Firmeza Ohata Gabriel Maia Bezerra João Victor souza das chagas Aloísio Vieira Lira Neto Adriano Bessa Albuquerque Victor Hugo Cde Albuquerque Pedro Pedrosa Rebouças Filho the Universidade Federal do Ceará FortalezaCE 60455-970and also with the Instituto Federal do CearáFortalezaCE 60040-215Brazil the Instituto Federal do Ceará FortalezaCE 60040-215Brazil the Universidade de Fortaleza FortalezaCE 60811-905Brazil

The new coronavirus(COVID-19),declared by the World Health Organization as a pandemic,has infected more than 1 million people and killed more than 50 *** infection caused by COVID-19 can develop into pneumonia,which can be detected by a chest X-ray exam and should be treated *** this work,we propose an automatic detection method for COVID-19 infection based on chest X-ray *** datasets constructed for this study are composed of194 X-ray images of patients diagnosed with coronavirus and 194 X-ray images of healthy *** few images of patients with COVID-19 are publicly available,we apply the concept of transfer learning for this *** use different architectures of convolutional neural networks(CNNs)trained on Image Net,and adapt them to behave as feature extractors for the X-ray ***,the CNNs are combined with consolidated machine learning methods,such as k-Nearest Neighbor,Bayes,Random Forest,multilayer perceptron(MLP),and support vector machine(SVM).The results show that,for one of the datasets,the extractor-classifier pair with the best performance is the Mobile Net architecture with the SVM classifier using a linear kernel,which achieves an accuracy and an F1-score of 98.5%.For the other dataset,the best pair is Dense Net201 with MLP,achieving an accuracy and an F1-score of 95.6%.Thus,the proposed approach demonstrates efficiency in detecting COVID-19 in X-ray images.

关键词： Convolutional neural networks(CNNs) COVID-19 transfer learning X-ray

High aluminum concentration and initial establishment of Handroanthus impetiginosus : clues about an Al non-resistant species in Brazilian Cerrado

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Journal of Forestry Research 2020年第6期31卷 2075-2082页

作者： Ane Marcela das chagas Mendon ca Jean Marcel Sousa Lira Ana Luiza de Oliveira Vilela Daniel Amorim Vieira Nayara Cristina de Melo Joao Paulo Rodrigues Alves Delfi no Barbosa Programa de Pós-Graduacao em Fisiologia Vegetal Departamento de BiologiaUniversidade Federal de LavrasLavrasMG 37200-000Brazil Programa de Pós-Graduacao em Ciências Ambientais Instituto de Ciências ExatasUniversidade Federal de AlfenasAlfenasMG 37130-001Brazil Programa de Pós-Graduacao em Fitotecnia Departamento de AgriculturaUniversidade Federal de LavrasLavrasMG 37200-000Brazil Instituto Federal de Educacao Ciência e Tecnologia do Pará BelémPA 66093-020Brazil

Cerrado soils are acidic and nutrient-poor,with high content of solubilized Al 3+.Plants growing in these conditions may display adaptations to cope with high aluminum concentrations especially during early developmental *** investigated leaf nutritional status,and photosynthetic and growth characteristics during the initial establishment of Handroanthus impetiginosus(*** Dc.)Mattos,a secondary tree species distributed in the Brazilian *** goal was to understand leaf-level traits related to diff erent aluminum *** plants were cultivated in four diff erent aluminum sulfate concentrations:0,1,2,and 4 mM Al,for 40 *** performed analyses of growth,leaf gas exchange,chloroplast pigment content,and leaf mineral *** observed a linear increase of Al leaf content as a function of Al concentration in the nutrient *** grown in 1 mM Al showed a remarkable increase of K leaf content,net photosynthesis,stomatal conductance,and transpiration,while in 4 mM Al there were reductions of N,P,and K contents,gas exchange characteristics,and *** did not have mechanisms of avoidance,compartmentalization,or resistance to high Al ***,this species showed a hormetic response,with low Al concentrations stimulating and high Al concentrations inhibiting plant responses.

关键词： Hormesis Low Al concentration Al toxicity Cerrado species Carbon assimilation

Chemical fixation of carbon dioxide to cyclic carbonates catalyzed by zinc(Ⅱ) complex bearing 1,2-disubstituted benzimidazole ligand

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Chinese Journal of Catalysis 2018年第2期39卷 245-249页

作者： Jorge L. S. Milani Igor S. Oliveira Pamella A. dos Santos Ana K. S. M. Valdo Felipe T. Martins Danielle Cangussu Rafael P.das chagas Universidade Federal de Goiás Instituto de Química Campus Samambaia CEP: 74690‐900 Goiania GO Brazil

A new zinc(II)complex of formula[ZnCl2(L1)2](1)[L1=2‐(2‐thienyl)‐1‐(2‐thienylmethyl)‐1Hbenzimidazole]was synthesized and fully characterized by nuclear magnetic resonance and infrared spectroscopy,elemental analysis,electrospray ionization high‐resolution mass spectrometry,and thermogravimetric *** molecular structure was confirmed by single‐crystal X‐ray ***1consists of mononuclear tetrahedral zinc(II)units with a locked geometry resulting from weak intramolecular S···?and?–?interligand *** benzimidazole ligand and its zinc(II)complex were readily obtained through a simple synthetic *** catalytic activity of1was investigated in the coupling of carbon dioxide with epoxides to produce cyclic carbonates,and a series of parameters were *** complex efficiently catalyzed the transformation of various epoxides under solvent‐free conditions,with good conversions,turnover numbers,and turnover frequencies.

关键词： Carbon dioxide Cyclic carbonate Zinc complex Benzimidazole ligand Cycloaddition Homogeneous catalysis

Community based interventions for the prevention and control of Non-Helmintic NTD

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Infectious Diseases of Poverty 2014年第1期3卷 223-234页

作者： Jai K das Rehana A Salam Ahmed Arshad Hasina Maredia Zulfiqar A Bhutta Division of Women&Child Health The Aga Khan UniversityKarachiPakistan Brown University ProvidenceRIUSA Center of Excellence in Women&Child Health The Aga Khan UniversityKarachiPakistan Center for Global Child Health Hospital for Sick ChildrenTorontoCanada

In this paper,we aim to systematically analyze the effectiveness of community based interventions(CBI)for the prevention and control of non-helminthic diseases including dengue,trypanosomiasis,chagas,leishmaniasis,buruli ulcer,leprosy and *** systematically reviewed literature published up to May 2013 and included 62 studies in this *** from our review suggest that CBI including insecticide spraying;insecticide treated bednets and curtains;community education and cleanliness campaigns;chemoprophylaxis through mass drug administration;and treatment have the potential to reduce the incidence and burden of non-helminthic *** of data limited the subgroup analysis for integrated and non-integrated delivery strategies however,qualitative synthesis suggest that integrated delivery is more effective when compared to vertical interventions;however,such integration was possible only because of the existing vertical vector control *** delivered interventions have the potential to achieve wider coverage and sustained community *** these diseases will require a multipronged approach including drug administration,health education,vector control and clean water and sanitation *** would require high level governmental commitment along with strong partnerships among major stakeholders.

关键词： NTDs Non-helminthic Community based interventions

The Effect of High Carbohydrate Consumption on Glucose Levels and Antibody Production in Nonobese Diabetic Mice

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Food and Nutrition Sciences 2016年第10期7卷 866-873页

作者： Tonicley Alexandre da Silva Caio José de Carvalho-Filho Elizabeth de Sousa Barcelos Barroqueiro Deysianne Costa das chagas Flá via Raquel Fernandes Nascimento Rosane Nassar Meireles Guerra Laboratory of Imunophysiology Universidade Federal do Maranh&atilde o S&atilde o Luí s Brazil

The aim of this study was to evaluate the effect of chronic treatment with diets rich in carbohydrates on the IgM and IgG antibody production and the seric glucose concentration in diabetes. Nonobese diabetic (NOD) mice received, ad libitum, by oral route, the diet consisting of an aqueous extract (20 mg/mL) of the following flours: babassu mesocarp, manioc, corn or rice, during 120 days. The diet intake was monitored throughout this period. At the end, the weight variation, blood glucose, serum IgG and IgM antibody and IgM anti-insulin titers, were determined. The babassu and manioc flour extracts altered Purina chow intake and these animals also presented a significant increase in body weight. In contrast, treatment with rice flour resulted in a significant weight loss. Moderate to severe hyperglycemia was observed in the groups receiving rice and manioc, whereas treatment with babassu mesocarp flour and cornmeal resulted in hypoglycemia. The extracts did not alter the IgG concentration. On the other hand, the cornmeal extract caused a marked reduction in both total IgM and anti-insulin IgM antibody production. Although babassu mesocarp flour, cornmeal and manioc flour caused important variations in the parameters studied, only treatment with the rice flour extract anticipated the onset of diabetes in male mice genetically predisposed to the disease.

关键词： Carbohydrates Diabetes Flour NOD Mice Diet

Percutaneous radiofrequency ablation for early hepatocellular carcinoma: Risk factors for survival

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World Journal of Gastroenterology 2014年第6期20卷 1585-1593页

作者： Luciana Kikuchi Marcos Menezes Aline L chagas Claudia M Tani Regiane SSM Alencar Marcio A Diniz Venncio AF Alves Luiz Augusto Carneiro D’Albuquerque Flair José Carrilho So Paulo Clínicas Liver Cancer Group Instituto do Cancer do Estado de So Paulo Hospital das Clínicas Department of Gastroenterology University of So Paulo School of Medicine So Paulo Clínicas Liver Cancer Group Instituto do Cancer do Estado de So Paulo Hospital das Clínicas Department of Radiology University of So Paulo School of Medicine So Paulo Clínicas Liver Cancer Group Instituto do Cancer do Estado de So Paulo Hospital das Clínicas Department of Pathology University of So Paulo School of Medicine

AIM: To evaluate outcomes of radiofrequency ablation (RFA) therapy for early hepatocellular carcinoma (HCC) and identify survival- and recurrence-related factors.

关键词： Hepatocellular carcinoma Radiofrequency ablation Overall survival Disease-free survival