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World Journal of Gastroenterology 2011年第44期17卷 4839-4844页

作者： Lodewijk AA Brosens Danielle Langeveld W Arnout van Hattem francis m giardiello G Johan A Offerhaus Department of Pathology University Medical Centre Utrecht Department of Pathology Academic Medical Centre Division of Gastroenterology Department of Medicine The Johns Hopkins University School of Medicine

Juvenile polyposis syndrome is a rare autosomal dominant syndrome characterized by multiple distinct juvenile polyps in the gastrointestinal tract and an increased risk of colorectal *** cumulative life-time risk of colorectal cancer is 39% and the relative risk is *** polyps have a distinctive histology characterized by an abundance of edematous lamina propria with inflammatory cells and cystically dilated glands lined by cuboidal to columnar epithelium with reactive ***,juvenile polyposis syndrome is defined by the presence of 5 or more juvenile polyps in the colorectum,juvenile polyps throughout the gastrointestinal tract or any number of juvenile polyps and a positive family history of juvenile *** about 50%-60% of patients diagnosed with juvenile polyposis syndrome a germline mutation in the SmAD4 or BmPR1A gene is *** genes play a role in the BmP/TGF-beta signalling *** has been suggested that cancer in juvenile polyposis may develop through the socalled "landscaper mechanism" where an abnormal stromal environment leads to neoplastic transformation of the adjacent epithelium and in the end invasive *** of this rare disorder is important for patients and their families with regard to treatment,follow-up and screening of at risk *** clinician confronted with the diagnosis of a juvenile polyp should therefore consider the possibility of juvenile polyposis *** addition,juvenile polyposis syndrome provides a unique model to study colorectal cancer pathogenesis in general and gives insight in the molecular genetic basis of *** review discusses clinical manifestations,genetics,pathogenesis and management of juvenile polyposis syndrome.

关键词： Juvenile polyposis syndrome Hamartoma Colorectal cancer SmAD4 BmPR1A

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Doped low-density parity-check codes

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Digital Communications and Networks 2024年第1期10卷 217-226页

作者： Yong Li Rui Liu Xianlong Jiao Youqiang Hu Zhen Luo francis C.m.Lau College of Computer Science Chongqing UniversityChongqing400044China School of Automation Chongqing UniversityChongqing400044China College of Electronic and Information Engineering Southwest UniversityChongqing400715China Future Wireless Networks and IoT Focusing Area Department of Electronic and Information EngineeringHong Kong Polytechnic UniversityHong KongChina

In this paper,we propose a doping approach to lower the error floor of Low-Density Parity-Check(LDPC)*** doping component is a short block code in which the information bits are selected from the coded bits of the dominant trapping sets of the LDPC ***,an algorithm for selecting the information bits of the short code is proposed,and a specific two-stage decoding algorithm is *** results demonstrate that the proposed doped LDPC code achieves up to 2.0 dB gain compared with the original LDPC code at a frame error rate of 10^(-6)Furthermore,the proposed design can lower the error floor of original LDPC Codes.

关键词： LDPC codes Doped LDPC codes Tanner graph Quadratic residue codes Trapping sets

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Understanding the catalysis of chromium trioxide added magnesium hydride for hydrogen storage and Li ion battery applications

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Journal of magnesium and Alloys 2024年第3期12卷 1117-1130页

作者： D.Pukazhselvan IhsanÇaha Catarina de Lemos Sergey m.mikhalev francis Leonard Deepak Duncan Paul Fagg Department of mechanical Engineering TEMA-Centre for Mechanical Technology and AutomationUniversity of AveiroAveiro 3810-193Portugal LASI-Intelligent Systems Associate Laboratory Guimarães 4800-058Portugal Nanostructured materials Group International Iberian Nanotechnology Laboratory(INL)Avenida Mestre Jose VeigaBraga 4715-330Portugal

This study explores how the chemical interaction between magnesium hydride(mgH_(2))and the additive CrO_(3) influences the hydrogen/lithium storage characteristics of mgH_(2).We have observed that a 5 wt.%CrO_(3) additive reduces the dehydrogenation activation energy of mgH_(2) by 68 kJ/mol and lowers the required dehydrogenation temperature by 80℃.CrO_(3) added mgH_(2) was also tested as an anode in an Li ion battery,and it is possible to deliver over 90%of the total theoretical capacity(2038 mAh/g).Evidence for improved reversibility in the battery reaction is found only after the incorporation of additives with mgH_(2).In depth characterization study by X-ray diffraction(XRD)technique provides convincing evidence that the CrO_(3) additive interacts with mgH_(2) and produces Cr/mgO *** free energy analyses confirm the thermodynamic feasibility of conversion from mgH_(2)/CrO_(3) to mgO/Cr,which is well supported by the identification of Cr(0)in the powder by X ray photoelectron spectroscopy(XPS)*** high resolution transmission electron microscopy(HRTEm)and energy dispersive spectroscopy(EDS)we found evidence for the presence of 5 nm size Cr nanocrystals on the surface of mgO rock salt *** is also convincing ground to consider that mgO rock salt accommodates Cr in the *** observations support the argument that creation of active metal–metal dissolved rock salt oxide interface may be vital for improving the reactivity of mgH_(2),both for the improved storage of hydrogen and lithium.

关键词： Hydrogen storage Rechargeable batteries Binary hydrides metal oxides Catalytic mechanism.

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Fuzzy Difference Equations in Diagnoses of Glaucoma from Retinal Images Using Deep Learning

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Computer modeling in Engineering & Sciences 2024年第4期139卷 801-816页

作者： D.Dorathy Prema Kavitha L.francis Raj Sandeep Kautish Abdulaziz S.Almazyad Karam m.Sallam Ali Wagdy mohamed Department of mathematics Voorhees CollegeVelloreTamil NaduIndia Chandigarh Group of Colleges JhanjeriMohaliPunjabIndia Department of Computer Engineering College of Computer and Information SciencesKing Saud UniversityP.O.Box 51178Riyadh11543Saudi Arabia Faculty of Science and Technology School of IT and SystemsUniversity of CanberraCanberraAustralia Operations Research Department Faculty of Graduate Studies for Statistical ResearchCairo UniversityGiza12613Egypt Applied Science Research Center Applied Science Private UniversityAmman11937Jordan

The intuitive fuzzy set has found important application in decision-making and machine *** enrich and utilize the intuitive fuzzy set,this study designed and developed a deep neural network-based glaucoma eye detection using fuzzy difference equations in the domain where the retinal images *** image detections are categorized as normal eye recognition,suspected glaucomatous eye recognition,and glaucomatous eye *** degrees associated with weighted values are calculated to determine the level of concentration between the fuzzy partition and the retinal *** proposed model was used to diagnose glaucoma using retinal images and involved utilizing the Convolutional Neural Network(CNN)and deep learning to identify the fuzzy weighted regularization between *** methodology was used to clarify the input images and make them adequate for the process of glaucoma *** objective of this study was to propose a novel approach to the early diagnosis of glaucoma using the Fuzzy Expert System(FES)and Fuzzy differential equation(FDE).The intensities of the different regions in the images and their respective peak levels were *** the peak regions were identified,the recurrence relationships among those peaks were then *** partitioning was done due to varying degrees of similar and dissimilar concentrations in the *** and dissimilar concentration levels and spatial frequency generated a threshold image from the combined fuzzy matrix and *** distinguished between a normal and abnormal eye condition,thus detecting patients with glaucomatous eyes.

关键词： Convolutional Neural Network(CNN) glaucomatous eyes fuzzy difference equation intuitive fuzzy sets image segmentation retinal images

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Technical efficiency of cocoa farms at varying elevation levels in Davao City, Philippines: implications to sustainable upland farming systems

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Journal of mountain Science 2024年第1期21卷 33-48页

作者： francis Levi A.DURANO Jon marx SARmIENTO Larry N.DIGAL Pedro A.ALVIOLA IV School of management University of the Philippines MindanaoDavao City 8000Philippines

Elevation is one of many components that influence agriculture, and this in turn affects the level of both inputs and outputs of farmers. This article focuses on the productivity and technical efficiency of 100 cocoa farms using cross-sectional data from areas ranging from 190 to 1021 m above sea level which were classified as low, medium, and high elevation in Davao City, considered as the chocolate capital of the Philippines. Using stochastic frontier analysis, the results showed that the cost of inputs per ha and the number of cocoa trees per ha significantly increase yield. Farms at high elevations were less technically efficient, as this entails lower temperatures and increased rainfall, and cocoa farming in those areas and conditions can be more challenging, especially with changes in farming practices, terrain, and distance to markets. Other significant variables were age of cocoa farms, married farmers, and age of the farmers. Older farms may be more developed, farmers who are married benefit from their spouses being able to readily contribute as farm labor, and lastly, older farmers' inefficiency may likely stem from nonadaptation of newer farming practices. With an average technical efficiency of 0.61, 0.63, and 0.26 in low, medium, and high elevation areas, respectively, farmers therefore have an incentive to improve farm practices and consider topographical variations found in high elevation areas. Recommendations for the improvement of technical efficiency of cocoa farms are better connectivity to markets, enhancing farm practices, and continuation and improvement of government programs on cocoa with an added emphasis on research. For farmers in high elevation areas, mitigating solutions such as sustainable agriculture practices and ecolabelling are key to improving efficiency and minimizing the potential negative impact on upland farming systems. moreover, such adaptation measures may also contribute to sustainability of cocoa farming in high elevation

关键词： Cocoa farms Cobb-Douglas production function Elevation Philippines Stochastic frontier analysis Technical efficiency

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Towards a new avenue for rapid synthesis of electrocatalytic electrodes via laser-induced hydrothermal reaction for water splitting

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International Journal of Extreme manufacturing 2024年第1期6卷 340-351页

作者： Yang Sha menghui Zhu Kun Huang Yang Zhang francis moissinac Zhizhou Zhang Dongxu Cheng Paul mativenga Zhu Liu Department of materials School of Natural SciencesThe University of ManchesterOxford RoadManchester M139PLUnited Kingdom Laser Processing Research Centre Department of MechanicalAerospace and Civil EngineeringSchool of EngineeringThe University of ManchesterOxford RoadManchester M139PLUnited Kingdom National Graphene Institute The University of ManchesterOxford RoadManchester M139PLUnited Kingdom Department of Chemical Engineering and Analytical Science School of EngineeringThe University of ManchesterOxford RoadManchester M139PLUnited Kingdom Research Centre for Laser Extreme manufacturing Ningbo Institute of Materials Engineering and TechnologyChinese Academy of SciencesNingboPeople’s Republic of China

Electrochemical production of hydrogen from water requires the development ofelectrocatalysts that are active,stable,and low-cost for water *** address these challenges,researchers are increasingly exploring binder-free electrocatalytic integratedelectrodes (IEs) as an alternative to conventional powder-based electrode preparation methods,for the former is highly desirable to improve the catalytic activity and long-term stability for large-scale applications of ***,we demonstrate a laser-inducedhydrothermal reaction (LIHR) technique to grow NimoO4nanosheets on nickel foam,which is then calcined under H2/Ar mixed gases to prepare the IE *** electrode exhibits superior hydrogen evolution reaction performance,requiring overpotentials of 59,116 and143 mV to achieve current densities of 100,500 and 1000 mA·*** the 350 h chronopotentiometry test at current densities of 100 and 500 m A·cm-2,the overpotentialremains essentially *** addition,NiFe-layered double hydroxide grown on Ni foam is also fabricated with the same LIHR method and coupled with IE-Nimo-IR to achieve water *** combination exhibits excellent durability under industrial current *** energy consumption and production efficiency of the LIHR method are systematicallycompared with the conventional hydrothermal *** LIHR method significantly improves the production rate by over 19 times,while consuming only 27.78%of the total energy required by conventional hydrothermal methods to achieve the same production.

关键词： electrocatalytic electrode laser-induced hydrothermal reaction NiFe layered double hydroxides hydrogen evolution reaction water splitting energy consumption production rate

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Estimating the Yield Loss of Winter Wheat from Drought in the United States Southern Plains Region as Influenced by El Niño-Southern Oscillation (ENSO)

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Agricultural Sciences 2024年第9期15卷 1018-1034页

作者： Prem Woli Gerald R. Smith Charles R. Long francis m. Rouquette, Jr. Texas A&m AgriLife Research Center Overton USA

Wheat (Triticum aestivum L.) production is a major economic activity in most regional and rural areas in the Southern Plains, a semi-arid region of the United States. This region is vulnerable to drought and is projected to experience a drier climate in the future. Since the interannual variability in climate in this region is linked to an ocean-atmospheric phenomenon, called El Niño-Southern Oscillation (ENSO), droughts in this region may be associated with ENSO. Droughts that occur during the critical growth phases of wheat can be extremely costly. However, the losses due to an impending drought can be minimized through mitigation measures if it is predicted in advance. Predicting the yield loss from an imminent drought is crucial for stakeholders. One of the reliable ways for such prediction is using a plant physiology-based agricultural drought index, such as Agricultural Reference Index for Drought (ARID). This study developed ENSO phase-specific, ARID-based models for predicting the drought-induced yield loss for winter wheat in this region by accounting for its phenological phase-specific sensitivity to drought. The reasonable values of the drought sensitivity coefficients of the yield model for each ENSO phase (El Niño, La Niña, or Neutral) indicated that the yield models reflected reasonably well the phenomena of water stress decreasing the winter wheat yields in this region during different ENSO phases. The values of various goodness-of-fit measures used, including the Nash-Sutcliffe Index (0.54 to 0.67), the Willmott Index (0.82 to 0.89), and the percentage error (20 to 26), indicated that the yield models performed fairly well at predicting the ENSO phase-specific loss of wheat yields from drought. This yield model may be useful for predicting yield loss from drought and scheduling irrigation allocation based on the phenological phase-specific sensitivity to drought as impacted by ENSO.

关键词： ARID Drought Drought Index ENSO El Niño Growth-Stage model Phenological-Phase Prediction Semi-Arid Wheat Yield Loss

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Estimating the Drought-Induced Yield Loss for Winter Wheat in a Semi-Arid Region of the Southern United States Using a Drought Index

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Agricultural Sciences 2024年第8期15卷 812-829页

作者： Prem Woli Qingwu Xue Gerald R. Smith Charles R. Long francis m. Rouquette Jr. Texas A&m AgriLife Research Center Overton Texas USA Texas A&m AgriLife Research Center Amarillo Texas USA

The economy of most rural locations in the semi-arid region of Llano Estacado in the southern United States is predominantly based on agriculture, primarily beef and wheat (Triticum aestivum L.) production. This region is prone to drought and is projected to experience a drier climate. Droughts that coincide with the critical phenological phases of a crop can be remarkably costly. Although drought cannot be prevented, its losses can be minimized through mitigation measures if it is predicted in advance. Predicting yield loss from an imminent drought is an important need of stakeholders. One way to fulfill this need is using an agricultural drought index, such as the Agricultural Reference Index for Drought (ARID). Being plant physiology-based, ARID can represent drought-yield relationships accurately. This study developed an ARID-based yield model for predicting the drought-induced yield loss for winter wheat in this region by accounting for its phenological phase-specific sensitivity to water stress. The reasonable values of the drought sensitivity coefficients of the yield model indicated that it could reflect the phenomenon of water stress decreasing the winter wheat yields in this region reasonably. The values of the various metrics used to evaluate the model, including Willmott Index (0.86), Nash-Sutcliffe Index (0.61), and percentage error (26), indicated that the yield model performed fairly well at predicting the drought-induced yield loss for winter wheat. The yield model may be useful for predicting the drought-induced yield loss for winter wheat in the study region and scheduling irrigation allocation based on phenological phase-specific drought sensitivity.

关键词： ARID Drought Drought index Growth-stage model Phenological-Phase Prediction Semi-Arid Wheat Yield

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Impact on Soil Organic C and Total Soil N from Cool- and Warm-Season Legumes Used in a Green manure-Forage Cropping System

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Agricultural Sciences 2024年第3期15卷 333-357页

作者： Clark B. Neely francis m. Rouquette Jr. Cristine L.S. morgan Frank m. Hons William L. Rooney Gerald R. Smith Department of Soil and Crop Science Washington State University Pullman WA USA Texas A&m AgriLife Research Overton TX USA Chief Scientific Officer Soil Health Institute Morrisville NC USA Department of Soil and Crop Science Texas A&M University College Station TX USA

Annual forage legumes are important components of livestock production systems in East Texas and the southeastern US. Forage legumes contribute nitrogen (N) to cropping systems through biological N fixation, and their seasonal biomass production can be managed to complement forage grasses. Our research objectives were to evaluate both warm- and cool-season annual forage legumes as green manure for biomass, N content, ability to enhance soil organic carbon (SOC) and soil N, and impact on post season forage grass crops. Nine warm-season forage legumes (WSL) were spring planted and incorporated as green manure in the fall. Forage rye (Secale cereale L.) was planted following the incorporation of WSL treatments. Eight cool-season forage legumes (CSL) were fall planted in previously fallow plots and incorporated as green manure in late spring. Sorghum-sudangrass (Sorghum bicolor x Sorghum bicolor var. sudanense) was planted over all treatments in early summer after forage rye harvest and incorporation of CSL treatments. Sorghum-sudangrass was harvested in June, August and September, and treatments were evaluated for dry matter and N concentration. Soil cores were taken from each plot, split into depths of 0 to 15, 15 to 30 and 30 to 60 cm, and soil C and N were measured using combustion analysis. Nylon mesh bags containing plant samples were buried at 15 cm and used to evaluate decomposition rate of above ground legume biomass, including change in C and N concentrations. mungbean (Vigna radiata L. [Wilczek]) had the highest shoot biomass yield (6.24 t Dm ha-1) and contributed the most total N (167 kg∙ha-1) and total C (3043 kg∙ha-1) of the WSL tested. Decomposition rate of WSL biomass was rapid in the first 10 weeks and very slow afterward. Winter pea (Pisum sativum L. spp. sativum), arrow leaf clover (Trifolium vesiculosum Savi.), and crimson clover (Trifolium incarnatum L.) were the most productive CSL in this trial. Austrian winter pea

关键词： Annual Legumes Soil N Soil Organic C Green manure Deer Browse Forage Cropping Systems

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Rescue from complications after pancreaticoduodenectomies at a low-volume Caribbean center:Value of tailored peri-pancreatectomy protocols

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World Journal of Gastrointestinal Surgery 2024年第3期16卷 681-688页

作者： Shamir O Cawich Elijah Dixon Parul J Shukla Shailesh V Shrikhande Rahul R Deshpande Fawwaz mohammed Neil W Pearce Wesley francis Shaneeta Johnson Johann Bujhawan Department of Surgery University of the West IndiesSt Augustine 000000Trinidad and Tobago Department of Surgery Faculty of MedicineUniversity of CalgaryCalgaryAlberta T2N2T9Canada Department of Surgery Weill Cornell Medical CollegeNew YorkNY 10065United States Department of Surgical Oncology Tata Memorial CenterHomi Bhabha National UniversityMumbai 400012India Department of Surgery Manchester Royal InfirmaryManchester M139WLUnited Kingdom University Surgical Unit Southampton General HospitalSouthampton SO166YDUnited Kingdom Department of Surgery University of the West IndiesNassau N-1184Bahamas Department of Surgery Morehouse School of MedicineAtlantaGA 30310United States Department of Surgery General Hospital in Port of SpainPort of Spain 000000Trinidad and Tobago

BACKGROUND Pancreaticoduodenectomy(PD)is a technically complex operation,with a re-latively high risk for *** ability to rescue patients from post-PD complications is as a recognized quality *** protocols were instituted at our low volume facility in the year *** To document the rate of rescue from post-PD complications with tailored protocols in place as a measure of *** A retrospective audit was performed to collect data from patients who experienced major post-PD complications at a low volume pancreatic surgery unit in Trinidad and Tobago between January 1,2013 and June 30,***-dardized definitions from the International Study Group of Pancreatic Surgery were used to define post-PD complications,and the modified Clavien-Dindo classification was used to classify post-PD *** Over the study period,113 patients at a mean age of 57.5 years(standard deviation[SD]±9.23;range:30-90;median:56)underwent PDs at this *** complications were recorded in 33(29.2%)patients at a mean age of 53.8 years(SD:±7.9).Twenty-nine(87.9%)patients who experienced major morbidity were salvaged after aggre-ssive treatment of their ***(3.5%)died from bleeding pseudoaneurysm(1),septic shock secondary to a bile leak(1),anastomotic leak(1),and myocardial infarction(1).There was a significantly greater salvage rate in patients with American Society of Anesthesiologists scores≤2(93.3%vs 25%;P=0.0024).CONCLUSION This paper adds to the growing body of evidence that volume alone should not be used as a marker of quality for patients requiring *** low volumes at our facility,we demonstrated that 87.9%of patients were rescued from major *** attributed this to several factors including development of rescue protocols,the competence of the pancreatic surgery teams and continuous,and adaptive learning by the entire institution,cul-minating in the development of tailored peri-pancreatectomy protoc

关键词： Pancreas Complication Rescue Failure morbidity mortality Pancreaticoduodenectomy

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