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Hypomanic/manic switch after transcranial magnetic stimulation in mood disorders:A systematic review and meta-analysis

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World Journal of Psychiatry 2021年第8期11卷 477-490页

作者： Andrea Miuli Gianna Sepede Gianfranco Stigliano Alessio Mosca francesco di carlo Giacomo d’Andrea Aliseo Lalli Maria Chiara Spano Mauro Pettorruso Giovanni Martinotti Massimo di Giannantonio Department of Neuroscience Imaging and Clinical Sciences“G.d'Annunzio”University of ChietiChieti 66100Italy Department of Psychiatry Affective Neuropsychiatry Sahlgrenska University HospitalGöteborg 40530Sweden Department of Pharmacy Clinical ScienceUniversity of HertfordshireHerts AL109ABItaly

BACKGROUND Nowadays there is an increasing use of transcranial magnetic stimulation(TMS)both in neurological and psychiatric *** Food and Drug Administration approval of TMS for the therapy of treatment-resistant depression,TMS has been widely used in the context of mood disorders(MD).However,growing reports regarding the possibility of developing hypomanic/manic switch(HMS)have generated concern regarding its use in *** To investigate the actual risk of developing HMS due to TMS in the treatment of *** We led our research on PubMed,Scopus and Web of Science on March 22,2020,in accordance to the PRISMA guidelines for systematic *** double blind/single blind studies,written in English and focused on the TMS treatment of MD,were included.A meta-analysis of repetitive TMS protocol studies including HMS was conducted using RevMan 5.4 *** assessment of Risk of Bias was done using Cochrane risk of bias *** protocol was registered on PROSPERO with the CRD42020175811 *** Twenty-five studies were included in our meta-analysis:Twenty-one double blind randomized controlled trials(RCT)and four single blind-RCT(*** subjects involved in active stimulation=576;*** subjects involved in sham protocol=487).The most frequently treated pathology was major depressive episode/major depressive disorder,followed by resistant depression,bipolar depression and other *** majority of the studies used a repetitive TMS protocol,and the left dorsolateral prefrontal cortex was the main target *** effects were reported in eight studies and HMS(described as greater energy,insomnia,irritability,anxiety,suicidal attempt)in four *** comparing active TMS vs sham treatment,the risk of developing HMS was not significantly different between *** Applying the most usual protocols and the appropriate precautionary measures,TMS seems not to be related to HMS development.

关键词： Hypomanic/manic switch Transcranial magnetic stimulation Active vs sham comparison Mood disorders Adverse event Safety

Thermal and chemical analysis of massive use of hot briquetted iron inside basic oxygen furnace

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Journal of Iron and Steel Research International 2017年第9期24卷 901-907页

作者： Cosmo di Cecca Silvia Barella carlo Mapelli Andrea Gruttadauria Andrea francesco Ciuffini Davide Mombelli Enrico Bondi Depatment of Mechanical Engineering Politecnico di MilanoMilano 20156Italy Freelance Milano 20100Italy

The integrated steelmaking cycle based on the blast furnace-basic oxygen furnace（BOF）route plays an important role in the production of plain and ultra-low carbon steel,especially for deep drawing *** steelmaking is based on the conversion of cast iron in steel by impinging oxygen on the metal bath at supersonic *** order to avoid the addition of detrimental chemical elements owing to the introduction of uncontrolled scrap and in order to decrease environmental impact caused by the intensive use of coke for the production of cast iron,HBI（hot briquetted iron）can be used as a source of metal and a fraction of cast *** industrial experimental tests were performed to evaluate the viability of the use of HBI in *** experimental campaign was supported by a thermal prediction model and realized through the estimation of the oxidation ***,the process was thermodynamically analyzed based on oxygen potentials using the off-gas composition and the bath temperature evolution during the conversion as reference data.

关键词： Hot briquetted iron Basic oxygen furnace Thermal analysis Chemical analysis Oxygen potential

Absolute parameters of the three totally-eclipsing W UMa stars NSVS 2443858,NSVS 780649 and V1098 Her

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Research in Astronomy and Astrophysics 2021年第9期21卷 124-134页

作者： Velimir Popov francesco Acerbi carlo Barani Department of Physics and Astronomy Shumen University115 Universitetska str.9700 ShumenBulgaria Via Zoncada 51 26845 Codogno(LO)Italy Via Molinetto 35 26845 Triulza di Codogno(LO)Italy

We present the first photometric analysis of three totally-eclipsing W UMa binaries,NS VS2443858,NSVS 780649 and V1098 *** absolute astrophysical parameters of the stellar components were determined by means of Gaia distances and light curve *** results show that:(ⅰ)Two of the systems,NSVS 2443858 and V1098 Her,are of A subtype while the obtained temperature of the secondary component of NSVS 780649 indicates that it is a W-subtype system;(ⅱ)The estimated mass ratios approach the lower limit of the mass ratio assumed by researchers in recent years so our targets could be classified as extreme mass ratio binary(EMRB)systems;(ⅲ)All the systems have deep contact configurations,so they also are deep low mass ratio(DLMR)systems;(ⅳ)The components of our systems are stars of F and G spectral type and undergo total eclipses;(ⅴ)The sum 0.871 M⊙of the component masses of NSVS 780649 is below the mass limit of 1.0-1.2 M⊙assumed for the known contact binary stars.

关键词： techinques:photometric binaries:eclipsing stars:fundamental parameters stars:individual

Cavitation as a zero-waste circular economy process to convert citrus processing waste into biopolymers in high demand

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Journal of Bioresources and Bioproducts 2024年第4期9卷 486-494页

作者： Rosaria Ciriminna Giuseppe Angellotti Giovanna Li Petri francesco Meneguzzo Cristina Riccucci Gabriella di carlo Mario Pagliaro Istituto per lo Studio dei Materiali Nanostrutturati CNRvia U.La Malfa 153Palermo90146Italy Istituto per la Bioeconomia CNRvia Madonna del Piano 10Sesto FiorentinoFI50019Italy Istituto per lo Studio dei Materiali Nanostrutturati CNRvia Salaria km 29.3MonterotondoRM00015Italy

Cavitation in water only, no matter whether hydrodynamic or acoustic, is a zero-waste circular economy process to convert industrial citrus processing waste into high-performance polysaccha- rides in high demand in a single-step at room temperature and ambient pressure using a modest amount of electricity as the only energy input. Following previous reports in which we used hydrodynamic cavitation, we now use an industrial acoustic sonicator to demonstrate the gen- eral viability of cavitation to convert biowaste residue of the industrial squeezing of pigmented sweet orange ( Citrus sinensis ) into highly bioactive “IntegroPectin ”pectin and micronized cellu- lose “CytroCell ”. From biomedicine through advanced composite membranes, said biomaterials hold great applicative potential. We conclude discussing the economic and technical feasibility of industrial implementation of the “CytroCav ”process.

关键词： Cavitation CytoCav CytroCell IntegroPectin Green extraction

DZ Lyn:a contact binary with components in poor thermal contact

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Research in Astronomy and Astrophysics 2009年第11期9卷 1270-1276页

作者： Massimiliano Martignoni francesco Acerbi carlo Barani Via Don G. Minzoni 26/D 20020 Magnago(MI)Italy Via Zoncada 51 26845 Codogno(LO)Italy Via Molinetto 35 26845 Triulza di Codogno(LO)Italy

CCD photometric observations of the short-period eclipsing binary DZ Lyn were obtained during seven nights in March-April 2008 in the B, V, Rc and Ic bands; these observations confirm the short-period （P = 0.378 d） of the system. The presented light curves are analyzed by means of the 2003 version of the Wilson-Devinney （WD） program. A grid of solutions for several fixed values of mass ratio was calculated. The best fitting possible is for a mass ratio of q -- 0.885, a degree of contact f = 0.18 and a low orbital inclination of i = 57.6°. The results show that DZ Lyn is an A-subtype W Ursae Majoris contact binary in poor thermal contact; in fact the difference between the mean temperatures of the components is about 1800 K. The star DZ Lyn seems to be another member of the class of poorly understood close binaries in or near geometrical contact but far from thermal contact. The absolute dimensions are estimated and its dynamical evolution is inferred.

关键词： binaries eclipsing -- stars fundamental parameters -- stars individual DZ Lyn

Photometric study and preliminary elements of the low-mass ratio W UMa system ASAS 021209+2708.3

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Research in Astronomy and Astrophysics 2011年第7期11卷 843-850页

作者： francesco Acerbi carlo Barani Massimiliano Martignoni Via Zoncada 51 26845 Codogno(LO)Italy Via Molinetto 35 26845 Triulza di Codogno(LO)Italy Via Don G.Minzoni 26/D 20020 Magnago(MI)Italy

We present CCD B and V light curves,obtained in the year 2006,and a photometric solution of the low-mass ratio contact binary ASAS 021209＋2708.3. With our data we were able to determine six new times of minimum light and refine the orbital period of the system to 0.3181963 *** light curves are analyzed using the 2003 version of the Wilson-Devinney program and the analysis was performed with and without adding a spot on the surface of one star because the light curves appear to exhibit a typical O’Connell effect,with Maximum I brighter than Maximum *** results show that ASAS 021209＋2708.3 may be classified as an A-subtype W Ursae Majoris system with a small mass ratio q=0.1889,a large over-contact degree of f= 0.587,a very small difference between the component temperatures of Δ T=53 K and an orbital inclination of i=81°.It is known that deep（f50%） ,low-mass ratio（q0.25） overcontact binary stars are a very important resource for understanding the phenomena of Blue Straggler/FK Com-type *** formations of Blue Straggler stars and FK Com-type stars are unsolved problems in stellar *** of the possible explanations for their formation is from the coalescence of W UMa-type overcontact binary *** absolute dimensions of ASAS 021209＋2708.3 are estimated and its dynamical evolution is inferred.

关键词： binaries:eclipsing–stars:fundamental parameters–stars:individual:ASAS 021209+2708.3

Prospective evaluation of a new device for the treatment of anal fistulas

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World Journal of Gastroenterology 2016年第30期22卷 6936-6943页

作者： carlo Ratto francesco Litta Lorenza Donisi Angelo Parello proctology unit Department of Surgical Sciences Catholic University 00168 Rome Italy

AIM: To evaluate the safety of the implantation of a new device for the treatment of anal fistulas. The short-term clinical efficacy was also assessed. METHODS: This study took place at a tertiary care university hospital. Patients with a complex anal fistula of cryptoglandular origin were enrolled in the study and were treated with insertion of the new device. All patients were evaluated by clinical and physical examination, including an endoanal ultrasound at the baseline, and then at the 2 wk and 1, 2, 3 and 6-mo follow-up visits. RESULTS: Morbidity, continence status, and success rate were the main outcome measures. Ten patients underwent the placement of the new device. The fistulas were transphincteric in eight patients and extrasphincteric in the remaining two. The median duration of the surgical procedure was 34.5(range, 27-42) min. Neither intra- nor postoperative complications occurred, and all patients were discharged the day after the procedure. At the 6-mo follow-up evaluation, the final success rate was 70%. Three failures were registered: a device expulsion(on the 10 th postoperative day), the persistence of inflammatory tissue around the fistula tract(at the 2-mo follow up), and the persistence of serum discharge(at the 6-mo follow up). No patient experienced any change incontinence, as assessed by the Cleveland Clinic Fecal Incontinence score. CONCLUSION: The technical procedure is simple and has low risk of perioperative morbidity. The pre- and post-operative continence status did not change in any of the patients. The initial results at the 6-mo follow up seem to be promising. However, a longer follow-up period and a larger sample size are needed to confirm these preliminary results.

关键词： Anal fistula Device Fistula plug Faecal incontinence Recurrence Endoanal ultrasound

A Novel Automatic Classification System Based on Hybrid Unsupervised and Supervised Machine Learning for Electrospun Nanofibers

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IEEE/CAA Journal of Automatica Sinica 2021年第1期8卷 64-76页

作者： Cosimo Ieracitano Annunziata Paviglianiti Maurizio Campolo Amir Hussain Eros Pasero francesco carlo Morabito the diCEAM University Mediterranea of Reggio Calabria89124 Reggio CalabriaItaly Politecnico of Turin 10129 TurinItaly the School of Computing Edinburgh Napier UniversityEdinburgh EH105DTUK

The manufacturing of nanomaterials by the electrospinning process requires accurate and meticulous inspection of related scanning electron microscope(SEM)images of the electrospun nanofiber,to ensure that no structural defects are *** presence of anomalies prevents practical application of the electrospun nanofibrous material in ***,the automatic monitoring and quality control of nanomaterials is a relevant challenge in the context of Industry *** this paper,a novel automatic classification system for homogenous(anomaly-free)and non-homogenous(with defects)nanofibers is *** inspection procedure aims at avoiding direct processing of the redundant full SEM ***,the image to be analyzed is first partitioned into subimages(nanopatches)that are then used as input to a hybrid unsupervised and supervised machine learning *** the first step,an autoencoder(AE)is trained with unsupervised learning to generate a code representing the input image with a vector of relevant ***,a multilayer perceptron(MLP),trained with supervised learning,uses the extracted features to classify non-homogenous nanofiber(NH-NF)and homogenous nanofiber(H-NF)*** resulting novel AE-MLP system is shown to outperform other standard machine learning models and other recent state-of-the-art techniques,reporting accuracy rate up to92.5%.In addition,the proposed approach leads to model complexity reduction with respect to other deep learning strategies such as convolutional neural networks(CNN).The encouraging performance achieved in this benchmark study can stimulate the application of the proposed scheme in other challenging industrial manufacturing tasks.

关键词： Anomaly detection autoencoder(AE) electrospinning machine learning material informatics nanomaterials

Photometric light curve solutions of three ultra-short period eclipsing binaries

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Research in Astronomy and Astrophysics 2020年第4期20卷 163-170页

作者： francesco Acerbi Raul Michel carlo Barani Massimiliano Martignoni Lexter Fox-Machado Stazione Astronomica Betelgeuse Magnago 20020Italy Instituto de Astronomia Universidad Nacional Autonoma de MexicoApartado Postal 877C.P.22800 EnsenadaB.C.Mexico

We present the results of our study of the eclipsing binary systems CSS J112237.1+395219,LINEAR 1286561 and LINEAR 2602707 based on new CCD B,V,Rcand Iccomplete light *** ultra-short period nature of these stars,as reported by Drake et al.,is confirmed and the system’s periods are *** light curves were modeled using the 2003 version of the Wilson-Devinney *** necessary,cool spots on the surface of the primary component were introduced to account for asymmetries in the light *** a result,we found that CSS J112237.1+395219 is a W UMa type contact binary system belonging to W subclass with a mass ratio of q=1.61 and a shallow degree of contact of 14.8%where the primary component is hotter than the secondary one by 500 *** 1286561 and LINEAR2602707 are detached binary systems with mass ratios q=3.467 and q=0.987 *** detached systems are low-mass M-type eclipsing binaries with similar *** marginal contact,fill-out factor and temperature difference between components of CSS J112237.1+395219 suggest that this system may be at a key evolutionary state predicted by thermal relaxation oscillation(TRO)*** the estimated absolute parameters,we conclude that our systems share common properties with other ultrashort period binaries.

关键词： techniques:photometric stars:variables:Contact Binary stars:individual:CSS J112237.1+395219 LINEAR 1286561 and LINEAR 2602707