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Recovery rates of persistent post-COVID-19 olfactory dysfunction using psychophysical assessment:A longitudinal cohort study

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第2期10卷 79-87页

作者： Jeremy P.Tervo Patricia T.Jacobson Brandon J.Vilarello Tiana M.Saak francesco f.caruana Liam W.Gallagher Joseph B.Gary David A.Gudis Paule V.Joseph D.P.Devanand Terry E.Goldberg Jonathan B.Overdevest Columbia University Vagelos College of Physicians and Surgeons New YorkNew YorkUSA Department of Otolaryngology-Head and Neck Surgery New York-Presbyterian/Columbia University Irving Medical CenterNew YorkNew YorkUSA Department of Otolaryngology-Head and Neck Surgery University of PittsburghPittsburghPennsylvaniaUSA Department of Otolaryngology-Head and Neck Surgery University of MinnesotaMinneapolisMinnesotaUSA National Institute of Alcohol Abuse and Alcoholism Section of Sensory Science and Metabolism&National Institute of Nursing ResearchBethesdaMarylandUSA New York-Presbyterian/Columbia University Irving Medical Center New YorkNew YorkUSA

Objectives:Persistent olfactory dysfunction(OD)following loss of smell associated with SARS-CoV-2 infection is a major feature of long *** on the prevalence of persistent OD predominantly rely on self-reported olfactory *** studies have tracked longitudinal rates of recovery using psychophysical assessment among patients presenting for evaluation of persistent OD beyond a window of acute *** anchored in standardized testing methods are needed to counsel patients who fail to acutely regain their sense of *** study aims to quantify the degree of persistent OD in post-COVID-19 patients who experience subjective and psychophysical ***:We grouped participants presenting for OD evaluation into cohorts based on both subjective and psychophysical olfactory status at a baseline assessment and assessed their olfactory abilities with a visual analogue scale and the Sniffin'Sticks extended test at baseline and 1-year time *** had confirmed a history of COVID-19 by lab evaluation or clinical diagnosis if lab evaluation was not ***:Baseline olfactory evaluation was completed by 122 participants,53 of whom completed the 1-year follow-up *** participants presenting with perceived OD,74.5%had confirmed psychophysical OD at baseline,with 55.1%at 1-year *** had reliable trends in self-rated versus psychophysically tested olfactory function at both time *** total threshold,discrimination,and identification(TDI)score improved by+3.25 points in the cohort with psychophysical OD(p=0.0005),with this improvement largely attributable to an increase in median threshold scores(+2.75 points;p=0.0004).Conclusions:OD persists in a significant number of patients who fail to acutely recovery their sense of smell after COVID-19,with many demonstrating lingering deficits at *** in threshold,but not discrimination or identification,most significantly mediate improvement

关键词： long COVID olfaction post-COVID condition smell dysfunction

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Histopathological evaluation of recurrent hepatitis C after liver transplantation:A review

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World Journal of Gastroenterology 2014年第11期20卷 2810-2824页

作者： francesco Vasuri Deborah Malvi Elisa Gruppioni Walter f Grigioni Antonia D'Errico-Grigioni "f. Addarii" Institute of Oncology and Transplantation Pathology S. Orsola-Malpighi HospitalBologna University40138 BolognaItaly

Although the morphological features of hepatitis C virus(HCV)recurrence after orthotopic liver transplantation(OLT)have been well established in the last decades,the differential diagnosis still represents a challenge for the pathologist,especially early recurrent hepatitis C vs mild acute cellular *** present review focuses on the role of the pathologist and the pathology laboratory in the management of recipients with recurrent hepatitis C,the usefulness of early and late post-OLT liver biopsies,and the potential role of ancillary techniques(immunohistochemistry and reverse transcription-polymerase chain reaction,RT-PCR).The English literature on the topic is reviewed,focusing on the histopathology,the immunohistochemistry and the use of RT-PCR on HCV-positive post-OLT *** different histopathological illustrations of early and chronic recurrent hepatitis C are presented,with special focus on the main differential diagnoses and those features with prognostic relevance(cholestasis above all).The usefulness of ancillary techniques are discussed,especially HCV RNA quantitation by ***,the usefulness of long-term protocol biopsies is addressed:their usefulness for the study of allograft disease progression is clear,but their meaning in the long term is still *** significance of plasma cell infiltrate in HCV-positive allografts,the prognostic weight of graft steatosis,and the impact of donor age in recurrent hepatitis C also represent additional open issues.

关键词： Hepatitis C virus Histopathology Immunohistochemistry Orthotopic liver transplantation Recurrent hepatitis C Polymerase chain reaction

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Thermal conductivity of glasses: first-principles theory and applications

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npj Computational Materials 2023年第1期9卷 1253-1274页

作者： Michele Simoncelli francesco Mauri Nicola Marzari Theory of Condensed Matter Group of the Cavendish Laboratory University of CambridgeCambridgeUK Dipartimento di fisica Universitàdi Roma La SapienzaRomaItaly Theory and Simulation of Materials(THEOS)and National Centre for Computational Design and Discovery of Novel Materials(MARVEL) École Polytechnique Fédérale de LausanneLausanneSwitzerland

Predicting the thermal conductivity of glasses from first principles has hitherto been a very complex *** established Allen-feldman and Green-Kubo approaches employ approximations with limited validity—the former neglects anharmonicity,the latter misses the quantum Bose-Einstein statistics of vibrations—and require atomistic models that are very challenging for first-principles ***,we present a protocol to determine from first principles the thermal conductivityκ(T)of glasses above the plateau(i.e.,above the temperature-independent region appearing almost without exceptions in theκ(T)of all glasses at cryogenic temperatures).The protocol combines the Wigner formulation of thermal transport with convergence-acceleration techniques,and accounts comprehensively for the effects of structural disorder,anharmonicity,and Bose-Einstein *** validate this approach in vitreous silica,showing that models containing less than 200 atoms can already reproduceκ(T)in the macroscopic *** discuss the effects of anharmonicity and the mechanisms determining the trend ofκ(T)at high temperature,reproducing experiments at temperatures where radiative effects remain negligible.

关键词： glasses conductivity harmonic

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Applying rock mass classifications to carbonate rocks for engineering purposes with a new approach using the rock engineering system

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Journal of Rock Mechanics and Geotechnical Engineering 2017年第2期9卷 364-369页

作者： Gioacchino francesco Andriani Mario Parise Dipartimento di Scienze della Terra e Geoambientali Università degli Studi di Bari Aldo MoroVia E. Orabona n. 4Bari 70125Italy

Classical rock mass classification systems are not applicable to carbonate rocks,especially when these are affected by karst *** applications to such settings could therefore result in outcomes not representative of the real stress-strain *** this study,we propose a new classification of carbonate rock masses for engineering purposes,by adapting the rock engineering system(RES) method by Hudson for fractured and karstified rock masses,in order to highlight the problems of implementation of geomechanical models to carbonate *** new approach allows a less rigid classification for carbonate rock masses,taking into account the local properties of the outcrops,the site conditions and the type of engineering work as well.

关键词： Rock mass classification Carbonates Karst Rock engineering system(RES)

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Absolute parameters of the three totally-eclipsing W UMa stars NSVS 2443858,NSVS 780649 and V1098 Her

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Research in Astronomy and Astrophysics 2021年第9期21卷 124-134页

作者： Velimir Popov francesco Acerbi Carlo Barani Department of Physics and Astronomy Shumen University115 Universitetska str.9700 ShumenBulgaria Via Zoncada 51 26845 Codogno(LO)Italy Via Molinetto 35 26845 Triulza di Codogno(LO)Italy

We present the first photometric analysis of three totally-eclipsing W UMa binaries,NS VS2443858,NSVS 780649 and V1098 *** absolute astrophysical parameters of the stellar components were determined by means of Gaia distances and light curve *** results show that:(ⅰ)Two of the systems,NSVS 2443858 and V1098 Her,are of A subtype while the obtained temperature of the secondary component of NSVS 780649 indicates that it is a W-subtype system;(ⅱ)The estimated mass ratios approach the lower limit of the mass ratio assumed by researchers in recent years so our targets could be classified as extreme mass ratio binary(EMRB)systems;(ⅲ)All the systems have deep contact configurations,so they also are deep low mass ratio(DLMR)systems;(ⅳ)The components of our systems are stars of f and G spectral type and undergo total eclipses;(ⅴ)The sum 0.871 M⊙of the component masses of NSVS 780649 is below the mass limit of 1.0-1.2 M⊙assumed for the known contact binary stars.

关键词： techinques:photometric binaries:eclipsing stars:fundamental parameters stars:individual

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On the classification of OADP varieties

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Science China Mathematics 2011年第8期54卷 1561-1575页

作者： CILIBERTO Ciro RUSSO francesco Dipartimento di Matematica Università di Roma Tor VergataVia della Ricerca Scientifica00133 RomaItaly Dipartimento di Matematica Università di CataniaViale A.Doria 695125 CataniaItaly

The main purpose of this paper is to show that OADP varieties stand at an important crossroad of various main streets in different disciplines like projective geometry,birational geometry and *** is a good reason for studying and classifying *** specific results are:(a) the classification of all OADP surfaces (regardless to their smoothness);(b) the classification of a relevant class of normal OADP varieties of any dimension,which includes interesting examples like lagrangian *** Pirio and Russo (Comm Math Helv,to appear),the equivalence of the classification in (b) with the one of quadro-quadric Cremona transformations and of complex,unitary,cubic Jordan algebras are explained.

关键词： apparent double points tangential projective cubic Jordan algebra

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Polymerization of 1,3-Butadiene with Catalysts Based on Cobalt Dichloride Complexes with Aminophosphines: Switching the Regioselectivity by Varying the MAO/Co Molar Ratio

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Chinese Journal of Polymer Science 2024年第4期42卷 501-510页

作者： Giovanni Ricci Anna Sommazzi francesco Masi Alessandra forni CNR-Istituto di Scienze e Tecnologie Molecolari“Giulio Natta”(SCITEC) via A.Corti 1220133MilanoItaly Viale Giovanni XXIII 34 I-28100NovaraNOItaly Via Galvani 7 I-26866Sant’Angelo LodigianoLOItaly CNR-Istituto di Scienze e Tecnologie Molecolari“Giulio Natta”(SCITEC) via C.Golgi 1920133MilanoItaly

Several novel cobalt dichloride complexes with amino-phosphine bidentate ligands were synthesized and *** some of them single crystals were obtained and their molecular structure was determined by X-ray diffraction *** the complexes were then used in combination with MAO for the polymerization of 1,3-butadiene,obtaining polymers with different structures(i.e.,predominantly 1,2 or cis-1,4)mainly depending on the type of ligand and on the MAO/Co molar *** behavior of these novel catalysts was compared with that exhibited,in the polymerization of the same monomer,by the systems CoCl_(2)(PR3)2-MAO and CoCl_(2)(PRPh2)2-MAO(R=alkyl or cycloalkyl group),and by the systems based on cobalt dichloride complexes with various bi-and tridentate ligands(e.g.,diphosphines,bis-imines,pyridyl-imines,bis-iminopyridines).The comparison between the different systems allowed us to make some clarity about the actual and effective role played by the various types of ligands in the polymerization of conjugated dienes with catalytic systems CoCl_(2)(L)-MAO,in which L=mono-,bi-,or tri-dentate ligand.

关键词： 1,3-Butadiene Stereospecific polymerization Cobalt catalysts Regioselectivity Aminophosphine ligands Crystal structures Chelate rings

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Suffocated shoots:Hypoxia-induced synthesis of salicylic acid inhibits plant regeneration

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Molecular Plant 2024年第4期17卷 528-530页

作者： Ximena Chirinos francesco Licausi Department of Biology University of OxfordSouth Parks RoadOxford OX13RBUK

Plant cells possess the unique ability to revert differentiated somatic cells back to a pluripotent state,a trait utilized in in vitro tissue *** plant propagation strategy involves the exogenous supplementation of auxin and cytokinin,two phytohormones that promote cellular reprogramming and de novo *** exposed to an auxin-rich medium,somatic cells proliferate and form the callus,a pluripotent cell *** the attainment of pluripotency,the callus can be transferred to a cytokinin-rich medium to induce shoot regeneration.

关键词： plant synthesis transferred

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Castaneda's Moral Theory and Globalization

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frontiers of Philosophy in China 2020年第1期15卷 122-142页

作者： francesco Orilia Department of Humanities Philosophy and Human Sciences SectionUniversity of MacerataMacerata 62100Italy

This paper examines the moral theory presented by Castaneda in his 1974 book The Stucture o f Morality and illustrates its usefulness in dealing with some intercultural phenomena concerning women and children rights which globalization has brought to the *** particular,Castaneda’s crucial distinction between moral codes and the moral ideal is ***,the role that freedom and happiness play in his framework is discussed and further elaborated by appealing to Berlin’s distinction between negative and positive freedom and current empirical studies on happiness.

关键词： morality happiness freedom values globalization

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Phase control of femtosecond pulses on the nanoscale using second harmonic nanoparticles

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Light(Science & Applications) 2014年第1期3卷 335-341页

作者： Nicolo Accanto Jana B Nieder Lukasz Piatkowski Marta Castro-Lopez francesco Pastorelli Daan Brinks Niek f van Hulst ICfO—Institut de Ciencies fotoniques 08860 Castelldefels(Barcelona)Spain Institut fresnel CNRS UMR7249Aix-Marseille University13397 MarseilleFrance ICREA—Institucio Catalana de Recerca i Estudis Avanc¸ats(ICREA) 08010 BarcelonaSpain

Investigations of ultrafast processes occurring on the nanoscale require a combination of femtosecond pulses and nanometer spatial ***,controlling femtosecond pulses with nanometer accuracy is very challenging,as the limitations imposed both by dispersive optics on the time duration of a pulse and by the spatial diffraction limit on the focusing of light must be overcome *** this paper,we provide a universal method that allows full femtosecond pulse control in subdiffraction-limited *** achieve this aim by exploiting the intrinsic coherence of the second harmonic emission from a single nonlinear nanoparticle of deep subwavelength *** method is proven to be highly sensitive,easy to use,quick,robust and *** approach allows measurements of minimal phase distortions and the delivery of tunable higher harmonic light in a nanometric ***,the method is shown to be compatible with a wide range of particle sizes,shapes and materials,allowing easy optimization for any given *** method will facilitate the investigation of light–matter interactions on the femtosecond–nanometer level in various areas of scientific study.

关键词： diffraction limit fourier limit multiphoton intrapulse interference phase scan nanoparticle nanophotonics phase control second harmonic generation ultrafast

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