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麻醉与镇痛 2008年第6期4卷 12-26,43页

作者： Tong J. Gan, MD Tricia A. Meyer, PharmD, Ms Christian C. Apfel, MD, PhD frances Chung, FRCPC Peter J. Davis, MD Ashraf s. Habib, MB, FRCA Vallire D. Hooper,MsN, RN, CPAN, FAAN Anthony L. Kovac,MD Peter Kranke, MD, PhD, MBA Paul Myles, MD Beverly K. Philip, MD Gregory samsa, PhD Daniel I. sessler, MD James Temo, CRNA, MsN, MBA Martin R. Tramer, MD, DPhil Craig Vander Kolk,MD Mehernoor Watcha, MD 谢郭豪(译) 方向明(校) Department of Anesthesiology Duke University Medical Center Durham North Carolina Consultant Anesthesiologist University of Wuerzburg WuerzburgGermany Department of Anesthesia and Perioperative Care UCSF Medical Center at Mt. Zion San FranciscoCalifornia Department of Anesthesia University of Toronto Toronto Canada Department of Anesthesi-ology and Pediatrics University of Pittsburgh School of Medicine Pittsburgh Pennsylvania school of Nurs-ing Medical College of Georgia Augusta Georgia Department of Anesthesiology University of KansasMedical Center Kansas City Kansas Consultant Anesthesiologist University of Wuerzburg WuerzburgGermam Department of Anesthesia and Perioperative Medicine Alfred Hospital Monash University Mel-bourne Australia Department of Anesthesiology Perioperative and Pain Medicine Brigham and Women'sHospital Harvard Medical School Boston Massachusetts Department of Biometry and Bioinformatics Duke University Medical Center Durham North Carolina Department of OUTCOMEs REsEARCH TheCleveland Clinic Cleveland Ohio Duke University Nurse Anesthetist Program Durham North Caro-lina Division of Anesthesiology Geneva University Hospitals and Faculty of Medicine Geneva Switzer-land Department of surgery Division of Plastic Surgery Johns Hopkins University School of Medicine Bal-timore Maryland Department of Anesthesiology Texas Children's Hospital Houston Texas 不详

本指南是在门诊手术麻醉协会发起下，由国际专家组编撰而成。该专家组成员涉及与手术后恶心、呕吐（PONV）相关的多个学科，他们审慎的评估了当前关于PONV的医学文献，为PONV高风险的成年及儿童外科手术患者提供了循证医学的参考工具。... 详细信息

本指南是在门诊手术麻醉协会发起下，由国际专家组编撰而成。该专家组成员涉及与手术后恶心、呕吐（PONV）相关的多个学科，他们审慎的评估了当前关于PONV的医学文献，为PONV高风险的成年及儿童外科手术患者提供了循证医学的参考工具。指南的重点是识别成人及儿童患者中发生PONV的危险因素；推荐降低PONV基础风险的方法；甄别出对PONV进行预防性治疗最为有效的单一药物及联合用药方案；推荐对已发生的PONV的治疗方法；并为具有较高PONV风险的患者提供了处理流程。

关键词：手术后恶心呕吐手术麻醉指南协会门诊 PONV 外科手术患者联合用药方案

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维持社区老年人身体活动能力的最佳证据总结和实践建议

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中华现代护理杂志 2023年第7期29卷 847-853页

作者：杨舒岚江碧艳金肖青俞莞琦黄金月王钧正朱雪娇刘彩霞浙江医院护理部杭州310000 浙江医院院长室杭州310000 上海交通大学医学院附属第六人民医院康复医学科上海200000 香港理工大学护理学院中国香港999077 杭州师范大学护理学院杭州310000

目的以证据的转化和应用为目标,聚焦维持社区老年人身体活动能力的策略,全面检索、整合相关最佳证据,形成实践建议,为相关证据的实施提供科学、可靠、与时俱进的依据。方法根据6s证据资源金字塔模型由上至下循序逐层检索BMJ Best Pract... 详细信息

目的以证据的转化和应用为目标,聚焦维持社区老年人身体活动能力的策略,全面检索、整合相关最佳证据,形成实践建议,为相关证据的实施提供科学、可靠、与时俱进的依据。方法根据6s证据资源金字塔模型由上至下循序逐层检索BMJ Best Practice、UpToDate、DynaMed、世界卫生组织、中华医学会、英国国家卫生与保健优化研究所、苏格兰校际指南网络、新西兰指南工作组、PubMed、中国生物医学文献服务系统等数据库,获取2017年1月1日—2022年3月1日与维持社区老年人身体活动能力相关的所有循证知识库资源、临床实践指南、专家共识、系统综述等类型的所有文献,根据文献纳入及排除标准进行筛选,按工具要求由2~4名研究员对不同类型文献进行独立的方法学质量评价,提取、汇总最佳证据,形成实践建议。结果共纳入14篇文献,其中循证决策2篇、指南6篇、专家共识1篇、系统评价3篇、系统评价再评价2篇。从"整体建议、健康收益、多样化运动训练、有氧训练、平衡训练、肌肉强化/抗阻训练、柔韧性训练"7个维度提取汇总了22条最佳证据,并形成实践建议。结论医护人员应采用基于循证方法学的实践建议对社区老年人维持身体活动能力进行管理指导和提供咨询,帮助老年人群更好地维持身体活动能力,从而获得更多健康收益。

关键词：老年人社区身体活动活动能力证据总结

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Abstracts from the 15th International Myopia Conference

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Eye and Vision 2016年第1期3卷 211-221页

作者： Alexandra Benavente-Perez Ann Nour Tobin Ansel Kathleen Abarr Luying Yan Keisha Roden David Troilo Chanyi Lu Miaozhen Pan Min Zheng Jia Qu Xiangtian Zhou Christine F. Wildsoet Fan Lu Jie Chen Jinhua Bao Liang Hu Qinmei Wang Zibing Jin frances Rucker stephanie Britton stephan Hanowsky Molly spatcher Hui-Ying Kuo Ching-Hsiu Ke I-Hsin Kuo Chien-Chun Peng Han-Yin sun Ian G. Morgan Jeremy A. Guggenheim Rupal L. shah Cathy Williams Jinglei Yang Peter s. Reinach sen Zhang Wenfeng sun Bo Liu Fen Li Xiaoqing Li Aihua Zhao Tianlu Chen Wei Jia Jun Jiang Haoran Wu Kazuo Tsubota Hiroko Ozawa Hidemasa Torii shigemasa Takamizawa Toshihide Kurihara Kazuno Negishi Klaus Graef Daniel Rathbun Frank schaeffel Ladan Ghodsi William K. stell Machelle T. Pardue Ranjay Chakraborty Han na Park Curran s. sidhu P. Michael Iuvone Michael J Collins Nethrajeith srinvasalu sally A. McFadden Paul N. Baird Pablo Artal Pauline Cho sW Cheung Pei-Chang Wu Quan V. Hoang Duk C. Lee Erica G. Landis Michael A. Bergen Curran sidhu samer Hattar Richard A. stone Ravi Metlapally Ruiqin Li Qinglin Xu Hong Zhong Chenglin Pan Weizhong Lan Xiaoning Li Ling Chen Zhikuan Yang scott A. Read seang-Mei saw shi-Jun Weng Xiao-Hua Wu Kang-Wei Qian Yun-Yun Li Guo-Zhong Xu Furong Huang Xiong-Li Yang Yong-Mei Zhong Earl L smith, III Baskar Arumugam Li-Fang Hung Lisa A. Ostrin Klaus Trier Monica Jong Brien A. Holden Thomas Chuen Lam samantha shan Bing Zuo Dennis Yan-yin Tse Jingfang Bian King-Kit Li Quan Liu Chi-ho To Timothy J. Gawne John T. siegwart, Jr. Alexander H. Ward Thomas T. Norton Yan Zhang Yue Liu Carol Ho Eileen Phan Abraham Hang Emily Eng Christine Wildsoet Department of Biological sciences SUNY College of Optometry New York NY 10036 USA school of Optometry and Ophthalmology and Eye Hospital Wenzhou Medical University Wenzhou Zhejiang 325027 China Center for Eye Disease & Development School of Optometry & Vision Science Program University of California Berkeley Berkeley CA 94720-2020 USA Wenzhou Medical University Wenzhou Zhejiang 325027 China Biomedical science and Disease New England College of Optom Boston MA USA school of Optometry Chung Shan Medical University Taichung City 402 Taiwan Institute of Medicine Chung Shan Medical University Taichung City 402 Taiwan Division of Biochemistry and Molecular Biology Research School of Biology Australian National University Canberra Australia state Key Laboratory of Ophthalmology and Division of Preventive Ophthalmology Zhongshan Ophthalmic Center Sun Yat-Sen University Guangzhou China school of Optometry & Vision sciences Cardiff University Cardiff UK school of social and Community Medicine University of Bristol Bristol UK school of and Eye Hospital Wenzhou Medical University Wenzhou Zhejiang 325027 China state Key Laboratory Cultivation Base and Key Laboratory of Vision science Ministry of Health and Zhejiang Provincial Key Laboratory of Ophthalmology and Optometry Wenzhou Zhejiang 325027 People’s Republic of China shanghai Key Laboratory of Diabetes Mellitus and Center for Translational Medicine Shanghai Jiao Tong University Affiliated Sixth People’s Hospital Shanghai 200233 China Eye Hospital of Wenzhou Medical University Wenzhou Zhejiang 325027 China Department of Ophthalmology Keio University School of Medicine Shinjuku-ku Tokyo 160-8582 Japan General Medicine Ichikawa Medical Center Urayasu City Chiba 279-0001 Japan Ophthalmic Research Institute University of Tuebingen 72076 Tuebingen Germany Bernstein Center for Computational Neuroscience Tuebingen 72076 Tuebingen Germany Werner Reichardt Centre for Integrative Neuroscience Otfried-Mueller-Straße 25 Tueb

To assess the peripheral refractive changes that occur when eye growth decelerates in *** We measured peripheral refraction and on-axis vitreous chamber depth on a total of 53 marmosets;36 treated monocularly for 12 weeks 9 hrs/day(26 with-5 D contact lenses,10 with+5 D)and 17 untreated *** the 26 marmosets treated with-5 D,10 wore contact lenses 9 hrs/day without interruptions and were mea-sured at the end of 10 weeks of treatment(T10)and after 4 weeks of recovery(R14).Eight had both contact lenses removed for 30 mins twice/day(mid-morning and mid-afternoon)during the first four weeks of treatment(early interruption group)and eight had the lenses removed during the second four weeks of treatment(late interruption group).The two interruption groups were measured after 4,8 and 12 weeks of treatment only(T4,T8,T12).

关键词： removed treatment untreated

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透皮东莨菪碱贴剂联合昂丹司琼对比单独应用昂丹司琼用于预防门诊手术后恶心呕吐的一项随机双盲多中心研究

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麻醉与镇痛 2010年第5期6卷 34-40页

作者： Tong J. Gan, MD Ashish C. sinha, MD, PhD Anthony L. Kovac, MD R. Kevin Jones, MD, CPI stephen A.Cohen,MD,MBA Jean P. Battildaa, Ms Jonathan s. Deutsch, MD Joseph V. Pergolizzi, Jr., MD] TDs study Group 王琦(译) 李文志(校) Department of Anesthesiology Duke University Medical Center Durham North Carolina University of Pennsylvania Philadelphia Pennsylvania ＊University of Kansas Medical Center Kansas City Kansas Accurate Clinical Trials Inc./saddleback Memorial Medical Center Laguna Hills California Beth Israel Deaconess Medical Center Boston Massachusetts Baxter Healthcare Corporation New Providence New Jersey Departrnent of Medicine Johns Hopkins University School of Medicine Baltimore Maryland The TDs study Group consists of the following members: Gregory H. Adkisson (st. Agnes Healthcare Inc. Baltimore MD St. Agnes Healthcare Inc. Clinical Research Center Baltimore MD) I(eith Candiotti(University of Miami School of Medidne Jackson Health Systems Miami FL) Stephen & Cohen(Beth Israel Deaconess Medical Center Boston MA) Nell R. Connelly(Baystate Medical Center Springfield MA) Patricia L. Dalby(Magee Women's Hospital of UPMC Pittsburgh PA) Robert D'Angelo(Forsyth Medical Center Winston-Salem NC) Albert R. Davis(Loyola University Medical Center Chicago IL) David 1L Drover (Stanford Hospital and Clinics Stanford CA) Tong J. Gan Fernando Altermatt Dianne Scott(Duke University Medical Center Durham NC Duke Health Raleigh Hospital Raleigh NC and Duke Center for Aesthetic Services Durham NC) Joseph S. Gimbel(AZ Research Center John C. Lincoln Hospital North Mountain and John C. Lincoln Hospital Deer Valley Phoenix AZ)R.Kevin Jones (Saddleback Memorial Medical Center Laguna Hills CA) Anthony L. Kovac(University of Kansas Medical Center Kansas City Kansas KS) John B. Leslie(Mayo Clinic Hospital Phoenix AZ) Roberta McI(inney Jr. (Trinity Clinic North Park Mother Frances Hospital and Tyler Square Tyler TX) Tricia A. Meyer ( Scott and White Hospital Temple TX ) Joseph Pergolizzi (Physicians Day Surgery Center Naples FL) Beverly tC Philip (Brigham and Women's Hospital Boston MA) Martin I. Redmond(State University of New York at Stony Brook Ambulatory Surgica

背景手术后恶心、呕吐（PONV）是门诊手术常见的并发症。本试验目的是观察透皮东莨菪碱贴剂（TDs）联合静脉注射昂丹司琼（OND）对门诊患者PONV的疗效是否优于单独应用昂丹司琼。方法此项随机双盲多中心的临床试验纳入了620例接受门诊... 详细信息

背景手术后恶心、呕吐（PONV）是门诊手术常见的并发症。本试验目的是观察透皮东莨菪碱贴剂（TDs）联合静脉注射昂丹司琼（OND）对门诊患者PONV的疗效是否优于单独应用昂丹司琼。方法此项随机双盲多中心的临床试验纳入了620例接受门诊腹腔镜或隆胸手术的PONV高危女性患者，进入手术室前2小时分别给患者贴上TDs贴剂或外观相同的空白贴剂。在全麻诱导前2—5分钟给所有患者静脉注射OND4mg。手术后24~48小时评估止吐是否完善（彻底止吐标准为无呕吐或干呕，且没有追加止吐药）。同时记录发生呕吐、干呕、恶心以及追加止吐药的患者比例，记录手术后首次发生PONV的时间及离院时间，记录呕吐、干呕、恶心的发作次数与严重程度及患者对于止吐治疗的满意度。结果TDs＋OND组与OND组相比，手术后24小时恶心、呕吐的发生率显著降低，但手术后48小时两者差异无显著性。TDs＋OND组没有呕吐、干呕且未追加过止吐药的患者占48％，而OND组占39％（P〈0．02）。TDs＋OND组的彻底止吐（无恶心、呕吐或干呕，且未追加止吐药）率显著高于OND组（分别为35％和25％，P〈0．01）。TDs＋OND组手术后首次发生恶心、呕吐、干呕及追加止吐药的时间明显晚于OND组（P〈0．05）。前者不良反应的总发生率也低于后者（分别为36．7％和49％，P〈0．01）。结论与单独应用OND相比。TDs＋OND能更大程度地减少PONV，主要是通过减少不良反应而获得。

关键词：手术后恶心呕吐东莨菪碱贴剂多中心研究昂丹司琼门诊手术随机双盲应用单独

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Effectiveness of Gardnerella vaginalis culture and Nugent scoring in identifying bacterial vaginosis in pregnant women

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Infectious Diseases Research 2023年第2期4卷 14-24页

作者： Chijioke Ogomegbunam Ezeigwe George Uchenna Eleje Chidebe Christian Anikwe David Chibuike Ikwuka Boniface Chukwuneme Okpala Kindness Chidi Irikannu Emeka Philip Igbodike Emmanuel Umegbolu Ngozichukwu Uzoewulu Olufunke Onaadepo Malarchy Ekwunife Nwankwo Onyecherelam Monday Ogelle Choice Chinemerem Nworgu Jide Uzowulu Uzoigwe Ifeoma frances Okwuonu Chisom Godswill Chigbo LazarusUgochukwu Okafor Chinekwu sochukwu Anyaoku Chukwuemeka Okwudili Ezeama Charlotte Blanche Oguejiofor Joseph Ifeanyichukwu Ikechebelu Department of Obstetrics and Gynaecology Nnamdi Azikiwe University Teaching Hospital NnewiAnambra State 435001Nigeria Department of Obstetrics and Gynaecology Nnamdi Azikiwe UniversityNnewi campus 435001Nigeria Department of Human Physiology Nnamdi Azikiwe UniversityNnewi Campus 435001Nigeria Department of Medical Physiology University of RwandaHuye CampusHuye 0000Rwanda Department of Parasitology and Entomology Nnamdi Azikiwe UniversityAwka 420007Nigeria Department of Outpatient Department General Hospital Oji River 401145Enugu StateNigeria Department of Medical Microbiology/Parasitology Nnamdi Azikiwe UniversityNnewi campus 435001Nigeria Department of Physiology University of Nigeria Enugu CampusEnugu 410001Nigeria Department of school of Public Health University of Port-HarcourtRivers State 500004Nigeria Department of Family Medicine Nnamdi Azikiwe University Teaching Hospital NnewiAnambra State 435001Nigeria.

Background:Bacterial vaginosis(BV),a lower genital tract syndrome,has been linked to adverse pregnancy outcomes and is regarded as the prevalent type of vaginal infection in females of childbearing ***:To determine the accuracy of Nugent scoring and Gardnerella vaginalis culture in the diagnosis of bacterial vaginosis(BV)among pregnant women attending antenatal clinic in Nnamdi Azikiwe University Teaching Hospital,Nnewi,***:This cross-sectional study evaluated biospecimen from 333 pregnant women enrolled through systematic random sampling *** of vaginal discharge were tested for BV infection using Amsel’s criteria,Nugent’s score and culture of *** Amsel’s criteria as a“gold standard”,the Nugent’s score and culture of *** were ***:Prevalence of 26.12%,25.82% and 28.20% of BV was found using Amsel criteria,Nugent’s method and culture of ***,*** statistical relationship exists between socio-demographic characteristics and BV(P>0.05).sexual exposure,and vaginal hygienic practices influences BV(Pso with fishy odor during or after sexual intercourse,Gardnerella morphotypes,Bacteroides morphotypes and BV(Pse relationship existed between lactobacilli morphotypes and *** prevalence of HIV was 5.41% and 16 out of 18 had BV diagnosed using Amsel *** method correlated strongly with Amsel criteria(Pson with Amsel criteria,it had 78.16% sensitivity,92.68% specificity,79.07% positive predictive value,92.31% negative predictive value and 88.89% accuracy *** was in contrast distinction to the culture of ***,which had 56.32%sensitivity,81.70% specificity,52.13% positive predictive value,84.10% negative predictive value and 75.08% accuracy ***:Nugent method correlated strongly with Amsel criteria(Psensitivity,92.68% specificity,79.07% positive predictive value,92.31% negative

关键词： Amsel criteria bacterial vaginosis Gardnerella vaginalis Nugent score pregnant women prevalence HIV

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