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Radiotherapy-induced heart disease:a review of the literature

Precision Clinical Medicine 2019年第4期2卷 270-282页

作者： Bingwen Zou Julius Philipp schuster Kerun Niu Qianyi Huang Alexander Rühle Peter Ernst Huber department of Radiation Oncology Heidelberg University HospitalIm Neuenheimer Feld 400Heidelberg 69120Germany department of Molecular Radiation Oncology German Cancer Research CenterIm Neuenheimer Feld 280Heidelberg 69120Germany Heidelberg Institute for Radiation Oncology(HIRO)and National Center for Radiation Oncology(NCRO) Im Neuenheimer Feld 280Heidelberg 69120Germany

Radiotherapy as one of the four pillars of cancer therapy plays a critical role in the multimodal treatment of thoracic *** to significant improvements in overall cancer survival,radiotherapy-induced heart disease(RIHd)has become an increasingly recognized adverse reaction which contributes to major radiationassociated toxicities including non-malignant *** is especially relevant for patients suffering from diseases with excellent prognosis such as breast cancer or Hodgkin’s lymphoma,since RIHd may occur decades after *** studies have enriched our knowledge of many potential mechanisms by which thoracic radiotherapy induces heart *** findings in humans reveal that irradiation might increase the risk of cardiac disease at even lower doses than previously *** preclinical studies have identified non-invasive methods for evaluation of ***,potential options preventing or at least attenuating RIHd have been *** research may enrich our limited knowledge about biological mechanisms of RIHd,identify non-invasive early detection biomarkers and investigate potential treatment options that might attenuate or prevent these unwanted side ***,we present a comprehensive review about the published literature regarding clinical manifestation and pathological alterations in *** mechanisms and treatment options are outlined,and challenges in RIHd treatment are summarized.

关键词： Radiotherapy heart injury thoracic cancer radiation-induced heart injury cancer treatment

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district Partisan Homogeneity, Communications, and the Electoral Motive: An Analysis of the Facebook Posts of Members of the U.S. House of Representatives

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Social Networking 2017年第2期6卷 148-163页

作者： Scot Schraufnagel Quan Li Adam schuster department of Political Science Northern Illinois University DeKalb Illinois USA College of Political Science and Public Administration Wuhan University Wuhan China Northern Illinois University DeKalb Illinois USA

The research examines the way in which members of the U.S. House of Representative represent themselves on the social network site Facebook. Each member’s activity is observed on seven different occasions and the frequency and substantive character of posts made during the second half of 2013 are established. The focus is on position-taking posts versus posts which mention the district the member serves in. Our expectation is that members from electorally safe districts will be more likely to advertise their policy positions while members from marginal districts will be more inclined to advertise their district connections. We control for minority party status, gender, and ideological extremism among other concerns and learn electoral safety is a good predictor of both “position-taking” and “district mentions”. Consistent with an electoral motive, we also find members from the minority party less likely to take positions on the issues of the day and more likely to mention the district they serve in.

关键词： U.S. House of Representatives Facebook Posts Electoral Motives Credit Claiming

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Increased Elongation at Breaking Point with Improved Mechanical Characteristics in PLA

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Open Journal of Composite Materials 2023年第2期13卷 13-28页

作者： Vishal Atnurkar Jens schuster Yousuf Pasha Shaik department of Applied Logistics and Polymer Sciences University of Applied Sciences Kaiserslautern Institute for Plastics Engineering West Pfalz (IKW) Pirmasens Germany

The main goal of this research was to increase the strength of Polylactic acid (PLA), an entirely biodegradable thermoplastic polyester, and an increase in elongation at the breaking point compared to neat PLA. To this end, S1, S2, and S3 were melt blended with various percentages of Zeolite, Glycerol, White vinegar, green camphor, Eucalyptus, and Carom seed oils. Here, the addition of glycerol, eucalyptus, and carom seed oils demonstrated an average improvement in impact and tensile strength of 13.44% and 14.55% respectively. Zeolite and glycerol work together as binding agents to improve stress transfer in the matrix, which increases tensile and flexural modulus as well as toughness elongation (>10%). The addition of the aforementioned materials led to an increase in the glass transition temperature and melting temperature, according to further dSC investigation. The thermal stability increased gradually, according to TGA data.

关键词： Polylactic Acid Biodegradable Thermoplastic Polyester Elongation Zeolite Glycerol Toughness Elongation Thermal Stability

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nNPipe: a neural network pipeline for automated analysis of morphologically diverse catalyst systems

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npj Computational Materials 2023年第1期9卷 2176-2187页

作者： Kevin P.Treder Chen Huang Cameron G.Bell Thomas J.A.Slater Manfred E.schuster doğanÖzkaya Judy S.Kim Angus I.Kirkland department of Materials University of OxfordParks RoadOX13PH OxfordOxfordshireUnited Kingdom Rosalind franklin Institute Harwell Research CampusOX110FA DidcotOxfordshireUnited Kingdom School of Chemistry The University of EdinburghEH93FJ EdinburghUnited Kingdom School of Chemistry Cardiff UniversityPark PlaceCF103AT CardiffUnited Kingdom Electron Physical Sciences Imaging Centre Diamond Light SourceOxfordshire OX110DEUnited Kingdom Johnson Matthey Technology Centre Blount’s CourtSonning CommonReading RG49NHUnited Kingdom

We describe nNPipe for the automated analysis of morphologically diverse catalyst materials. Automated imaging routines anddirect-electron detectors have enabled the collection of large data stacks over a wide range of sample positions at high temporalresolution. Simultaneously, traditional image analysis approaches are slow and hence unsuitable for large data stacks andconsequently, researchers have progressively turned towards machine learning and deep learning approaches. Previous studiesoften detail work on morphologically uniform material systems with clearly discernible features, limited workable image sizes andtraining data that may be biased due to manual labelling. The nNPipe data-processing method consists of two standaloneconvolutional neural networks that were exclusively trained on multislice image simulations and enables fast analysis of2048 × 2048 pixel images. Inference performance compared between idealised and real industrial catalytic samples and insightsderived from subsequent data analysis are placed into the context of an automated imaging scenario.

关键词： catalyst hence subsequent

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Exploring the Potential to Uniquely Manufacture Curved VARTM Epoxy Composites Using Cost-Effective FdM Molds

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Open Journal of Composite Materials 2020年第3期10卷 45-65页

作者： Syed Monis Raza Kazmi Jens schuster Johannes Lutz Hochschule Kaiserslautern University of Applied Sciences Pirmasens Germany

The Resin Infusion or the VARTM (Vacuum Assisted Resin Transfer Molding) process has significant potential to be used to manufacture curved composites. Another way to produce curved or complex geometry is to use 3d printers. 3d or FdM (Fused deposition Modelling) printers are now being used to produce relatively cheaper curved parts using thermoplastics such as PLA. However, the strength and mechanical performance of these parts is limited and can be enhanced if the polymer is reinforced with a type of fiber for instance. Research is being carried out to produce fiber rein-forced thermoplastic composites but that process is expected to be more expensive than the alternative methods such as injection or compression molding. Furthermore, to understand the manufacture of a hybrid composite using thermoplastics, fibers and epoxy resin, research and investigation need to be carried out. In this research, there are single-sided, double-sided, reusable, disposable and consumable molds. Most of the molds were created either using an FDM printer or manually. These molds were then used to manufacture flat and curved composite structures via the resin injection process, i.e.dana;"> VARTM with epoxy resin system and glass/carbon/flax fiber reinforcement. By replacing the costly metallic molds by significantly cheaper molds, the cost of production was expected to further reduce. Furthermore, using double-sided PLA molds was not expected to be a threat to the overall cost of the composite part in question compared to double-sided matched molds used in compression molding. Shear

关键词： 3d Printing FdM VARTM Curved Composites 3d Molds Reusable Molds Consumable Molds disposable Molds

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小儿EB病毒感染的诊断和治疗

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国外医学（流行病学．传染病学分册） 1993年第3期20卷 127-129页

作者： schuster V 兰节

本文综述了EB病毒感染的病毒学和血清学诊断方法,以及EB病毒感染的治疗和预防。

关键词：儿童 E-B病毒感染诊断

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Manufacturing and Product Analysis of Non-Woven and Paper Based Epoxy Composites

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Open Journal of Composite Materials 2023年第2期13卷 29-45页

作者： Vinay Kumar Kotike Jens schuster Yousuf Pasha Shaik department of Applied Logistics and Polymer Sciences University of Applied Sciences Kaiserslautern Institute for Plastics Engineering West Pfalz (IKW) Pirmasens Germany

Fiber-reinforced polymer composites are used in a wide variety of applications due to their many advantages, such as relatively low production costs, ease of fabrication, and superior strength compared to pure polymer resins. Polymer reinforcement can be either synthetic or natural. Synthetic fibers such as carbon have high specific strength, but their application fields are limited due to their high manufacturing cost. Recently, interest in recycled fiber-based composites has increased due to their many advantages. In this context, research has been carried out to better utilize non-woven and paper-based materials to make value-added products. The aim of the current research work is to compare the mechanical performance of non-woven and paper-based reinforced epoxy composites manufactured by the VARTM process. Mechanical properties such as tensile strength, flexural strength (using three-point bending), impact strength, hardness strength, and water absorption were measured. A multi-criteria decision approach called TOPSIS (The Technique for Order of Preference by Similarity to Ideal Solution) was used to select the best alternative from the investigated materials.

关键词： Recycled Fibers Nonwovens and Papers VARTM Mechanical Properties TOPSIS

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Phase Equilibria of the Al-Mn-Si System over the Entire Composition and Temperature Ranges: Modeling and Experiment

Phase Equilibria of the Al-Mn-Si System over the Entire Comp...

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第十二届全国相图学术会议

作者： J．C．schuster Institut für Physikalische Chemie Universit（a|¨）t Wien W（a|¨）hringerstrasse 42 A-1090 WienAustria

The Al-Mn binary system is reassessed by considering our new experimental data. And a thermodynamic modeling for the Al-Mn-Si system is conducted via two steps. In the first step, all of the experimen

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development of Ecological Absorbent Core Sanitary Pads in Combination of Kenaf and Chitosan Fibers

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Materials Sciences and Applications 2023年第7期14卷 363-381页

作者： desh Maruthi Jeyakanthan Jens schuster Yousuf Pasha Shaik department of Applied Logistics and Polymer Sciences University of Applied Sciences Kaiserslautern Institute for Plastics Engineering West Pfalz (IKW) Pirmasens Germany

The menstrual cycle is always considered as a big nightmare by many women. This research aims to make this process smooth and safe by developing natural sanitary pads which are used to absorb and retain menstrual blood from the body. Some existing sanitary pads contain 90% plastics made of non-woven polypropylene/polyethylene sheets, super absorbent polymers, and polyethylene back sheets that will take up to 600 - 800 years to decompose. So, biodegradable sanitary pads using natural fibers are the best alternative to eliminate the pads which contain non-biodegradable materials. In this research, nonwoven bamboo will be used as the top layer, nonwoven cotton will be used as the second layer, the absorbent core is to be made by the combination of kenaf and chitosan fibers as the third layer, cotton as the fourth layer, and cornstarch-based bioplastic sheets as the bottom layer. These biodegradable natural materials will change the menstrual process into a healthy one as well as create a robust ecological community.

关键词： Sanitary Pads Biodegradable Kenaf Chitosan Bamboo Cotton Corn-Based Polylactic Acid

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Normative data for TM electrocochleography measures

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Journal of Otology 2017年第2期12卷 68-73页

作者： Signe schuster Grasel Roberto Miquelino de Oliveira Beck ricardo Silva Chiabai Loureiro Amanda Costa Rossi Edigar Rezende de Almeida John Ferraro University of Sao Paulo School of Medicine Dr.Eneas de Carvalho Aguiar255sala 6173Cerqueira CesarSao PauloSP CEP 05403-000Brazil University of Kansas Medical Center Kansas CityKS 66160USA

Objective: Establish normative data for tympanic electrocochleography(TM ECoch G) parameters in normal hearing adults without Meniere's disease's(Md) symptoms. describe TM ECoch G variables that help to distinguish normal from Md *** and methods: We enrolled 100 subjects(N =200 ears), 59 females, aged between 19 and 71 years from 09/2010 to 04/2014. Inclusion criteria: normal otomicroscopy, hearing thresholds≤25 dB nHL from 250 to 4000 Hz, normal tympanogram, no symptoms of Md according to the AAO-HNS 1995 criteria and Gibson's score ded subjects with dizziness, aural fullness or other symptoms of endolymphatic hydrops. The following parameters were analyzed: SP/AP amplitude ratio, SP/AP area ratio and the difference between AP latency with rarefaction and condensation ***: There was no significant difference between right and left ears(Intraclass correlation coefficient de ratio varied between 0.084 and 0.356 and SP/AP area ratio between 0.837 and 1.671(percentiles 5 and 95). The AP latency difference to rarefaction and condensation clicks was between 0.0 and 0.333 ***: Normative data for TM ECoch G parameters were established in 100 normal hearing subjects without Md. These data can be used to distinguish normal from pathological findings and in follow-up of Md patients.

关键词： Electrocochleography Meniere disease Hearing dizziness Tinnitus

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