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General Psy.hiatry 2024年第1期37卷 173-176页

作者： Jack Jiaqi Zhang Zhongfei Bai Kenneth N K fong Department of Rehabilitation Sciences The Hong Kong Polytechnic UniversityHong KongChina Shanghai y.ngZhi Rehabilitation Hospital(Shanghai Sunshine Rehabilitation Centre) School of MedicineTongji UniversityShanghaiChina

INTRODUCTION Repetitive transcranial magnetic stimulation(rTMS)is a neuroplasticity.enhancing technique that modifies brain responsiveness to various therapeutic modalities in clinical psy.hiatric and neurological applications. Furthermore,its effect can be attributed to long-term potentiation(LTP)or longterm depression(LTD)-like ***,responsiveness to rTMS is largely.variable in healthy.and pathological brains and is mediated by.complex biological *** refers to a higher-order plasticity.mechanism in which the direction and magnitude of sy.aptic plasticity.are modified by.prior neuronal activity.and is believed to be a significant factor leading to the response variability.of rTMs.

关键词： stimulation clinical transcranial

脑静脉血栓形成的诊断和处理美国心脏协会／美国卒中协会对医疗专业人员的声明

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国际脑血管病杂志 2011年第10期19卷 724-757页

作者： Gustavo Saposnik Femando Barinagarrementeria Robert D. Brown Chery. D. Bushnell Brett Cucchiara Mary.Cushman Gabrielle deVeber Jose M. Ferro fong y. tsai 张沈阳（译）韩丽娟（译）叶丹（译）徐运（译）不详南京医科大学鼓楼临床学院 210008 南京大学医学院附属鼓楼医院神经内科 210008

背景本指南旨在对脑静脉窦血栓形成（cerebral venous sinus thrombosis，CVT）进行概述，并提供其诊断、处理和治疗的推荐意见，目标读者为涉及CVT患者诊断和处理的临床医生和其他医疗工作者。方法和结果作为不同专业领域的代表，专家... 详细信息

背景本指南旨在对脑静脉窦血栓形成（cerebral venous sinus thrombosis，CVT）进行概述，并提供其诊断、处理和治疗的推荐意见，目标读者为涉及CVT患者诊断和处理的临床医生和其他医疗工作者。方法和结果作为不同专业领域的代表，专家小组成员由美国心脏协会（American Heart Association，AHA）卒中委员会科学声明监督委员会任命。专家小组回顾了相关文献，重点为1966年以来公开发表的报道，并使用AHA证据水平分级方案对证据进行评定并制定推荐意见。本指南经专家小组认可后，由AHA科学咨询和协调委员会进行同行评议并批准。结论本指南为CVT的诊断、处理和复发的预防提供了循证推荐，同时还提供了妊娠期妇女和儿童CVT评估和处理的推荐意见，对临床并发症（痫性发作、脑积水、颅内压增高和神经功能恶化）的处理进行了总结，并描述了CVT患者诊断和治疗的流程图。

关键词：美国心脏协会科学声明静脉血栓形成静脉窦血栓形成,颅内脑梗死,静脉卒中疾病管理预后转归评价抗凝药妊娠儿童

Unilateral rNurr1-V5 transgene expression in nigral dopaminergic neurons mitigates bilateral neuropathology.and behavioral deficits in parkinsonian rats withα-sy.ucleinopathy

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Neural Regeneration Research 2024年第9期19卷 2057-2067页

作者： Bismark Gatica-Garcia Michael J.Bannon Irma Alicia Martínez-Dávila Luis O.Soto-Rojas David Rey.s-Corona Lourdes Escobedo Minerva Maldonado-Berny.ME Gutierrez-Castillo Armando J.Espadas-Alvarez Manuel A.Fernandez-Parrilla Juan U.Mascotte-Cruz CP Rodríguez-Oviedo Irais E.Valenzuela-Arzeta Claudia Luna-Herrera Francisco E.Lopez-Salas Jaime Santoy.-Salazar Daniel Martinez-fong Departamento de Fisiología Biofísica y NeurocienciasCentro de Investigación y de Estudios AvanzadosCiudad de MéxicoMéxico Department of Pharmacology Wayne State University School of MedicineDetroitMIUSA Laboratorio de Patogénesis Molecular Carrera Médico CirujanoFacultad de Estudios Superiores IztacalaUniversidad Nacional Autónoma de MéxicoTlalnepantla de BazMéxico Red de Medicina para la Educación y.Desarrollo y.la Investigación Científica de Iztacala(Red MEDICI) Carrera Médico CirujanoFacultad de Estudios Superiores IztacalaUniversidad Nacional Autónoma de MéxicoTlalnepantla de BazMéxico Nanoparticle Therapy.Institute AguascalientesMéxico Departamento de Biociencias e Ingeniería Centro Interdisciplinario de Investigaciones y Estudios sobre Medio Ambiente y DesarrolloInstituto Politécnico NacionalCiudad de MéxicoMéxico Escuela Nacional de Medicina y.Homeopatía Instituto Politécnico NacionalCiudad de MéxicoMéxico Departamento de Fisiología Escuela Nacional de Ciencias BiológicasInstituto Politécnico NacionalCiudad de MéxicoMéxico Departamento de Biología Molecular y.Biotecnología Instituto de Investigaciones BiomédicasUniversidad Nacional Autónoma de MéxicoCiudad de MéxicoMéxico Departamento de Física Centro de Investigación y de Estudios AvanzadosCiudad de MéxicoMéxico Programa de Nanociencias y.Nanotecnología Centro de Investigación y de Estudios AvanzadosCiudad de MéxicoMéxico

Parkinsonism by.unilateral,intranigralβ-sitosterolβ-D-glucoside administration in rats is distinguished in that theα-sy.uclein insult begins unilaterally.but spreads bilaterally.and increases in severity.over time,thus replicating several clinical features of Parkinson’s disease,a ty.icalα-*** Nurr1 repressesα-sy.uclein,we evaluated whether unilateral transfected of rNurr1-V5 transgene via neurotensin-poly.lex to the substantia nigra on day.30 after unilateralβ-sitosterolβ-D-glucoside lesion could affect bilateral neuropathology.and sensorimotor deficits on day.30 *** study.found that rNurr1-V5 expression but not that of the green fluorescent protein(the negative control)reducedβ-sitosterolβ-D-glucoside-induced ***,a bilateral increase in ty.osine hy.roxy.ase-positive cells and arborization occurred in the substantia nigra and increased ty.osine hy.roxy.ase-positive ramifications in the *** addition,ty.osine hy.roxy.ase-positive cells display.d less senescence markerβ-galactosidase and more neuron-cy.oskeleton markerβIII-tubulin and brain-derived neurotrophic factor.A significant decrease in activated microglia(positive to ionized calcium-binding adaptor molecule 1)and neurotoxic astrocy.es(positive to glial fibrillary.acidic protein and complement component 3)and increased neurotrophic astrocy.es(positive to glial fibrillary.acidic protein and S100 calcium-binding protein A10)also occurred in the substantia *** effects followed the bilateral reduction inα-sy.uclein aggregates in the nigrostriatal sy.tem,improving sensorimotor *** results show that unilateral rNurr1-V5 transgene expression in nigral dopaminergic neurons mitigates bilateral neurodegeneration(senescence and loss of neuron-cy.oskeleton and ty.osine hy.roxy.ase-positive cells),neuroinflammation(activated microglia,neurotoxic astrocy.es),α-sy.uclein aggregation,and sensorimotor *** neurotrophic astrocy.es and

关键词： A1 astrocy.es A2 astrocy.es gene therapy microglia motor deficits nanoparticles neurodegeneration neuroinflammation senescence α-sy.uclein aggregates

High speed small gauge anterior vitrectomy.cutter for scleral fixated intraocular lens implantation

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International Journal of Ophthalmology.English edition) 2017年第1期10卷 77-80页

作者： y.an Bo Liang y.ly.y.y. fong Lulu L. Cheng Alvin L. y.ung Clinical and Epidemiological Ey. Research Center the Affiliated Eye Hospital School of Optometry and OphthalmologyWenzhou Medical University Wenzhou 325027 ZhejiangProvince China Department of Ophthalmology.＆ Visual Sciences the ChineseUniversity of Hong Kong Prince of Wales Hospital ShatinHong Kong China

AIM： To report the outcomes of anterior vitrectomy.using high speed cutter for scleral fixated intraocular lens （SFIOL） implantation in patients with posterior capsular rupture .METHODS： Medical records of 51 patients with posterior capsular rupture who received high speed cutter anterior vitrectomy.via limbal incision with SFIOL implantation from June 2011 to December 2013 were reviewed retrospectively.for visual outcomes and ***： Totally.51 ey.s of 51 patients were identified （23 males and 28 females）. Mean age at surgery.was 67.2±15y.（range 27-91y., with mean follow-up of 23±8.2mo （range 12-40mo）. The 49 （96.1%） ey.s had improvement or unchanged of final postoperative visual acuity. The most common complication was vitreous haemorrhage （5.9%） and transient rise in intraocular pressure （5.9%） which all spontaneously.resolved CONCLUSION： High speed cutter anterior vitrectomy.via limbal incision is a safe and effective method for those with posterior capsular rupture for SFIOL implantation.

关键词： cataract aphakia posterior capsular rupture intraocular lens scleral fixation

Robot-assisted minimally.invasive procedures for complicated biliary.stone disease

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Hepatobiliary.Surgery.and Nutrition 2018年第3期7卷 185-188页

作者： Kit Fai Lee Andrew K. y. Fung Hon Ting Lok Anthony.K. W. fong Charing C. N. Chong Paul B. S. Lai Division of Hepatobiliary.and Pancreatic Surgery Department of SurgeryPrince of Wales HospitalThe Chinese University of Hong KongHong KongChina

Introduction A big advancement in endoscopic management for biliary.stone diseases was seen in the past three decades. Bile duct stones can be removed after sphincterotomy.or balloon sphincteroplasty.with stone basket... 详细信息

关键词： balloon biliary diseases

Adsorption Isotherm Study.of Activated Fruit Peels for Copper Removal

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Journal of Harbin Institute of Technology.New Series) 2022年第3期29卷 93-100页

作者： S.y.Tai L.L.fong M.K.Chan P.K.Bullar Centre for Water Research Faculty of EngineeringBuilt Environment and Information TechnologySEGi University Sdn BhdPetaling Jaya 47810SelangorMalaysia

Heavy.metal polluted water threatens the integrity.of *** use of agricultural waste as adsorbent becomes popular due to its biodegradability.and ***,limited research works has been done to process agricultural waste for heavy.metal adsorption *** objective of this study.is to propose a new approach to treat banana peel using ZnCl_(2) prior to alkali and acid treatment and explore the potential of dragon fruit peels as the adsorbent for Cu^(2+)*** adsorption isotherm was adopted to identify.the adsorption mechanism and four statistical parameters were calculated for model verification *** experiment was conducted by.dispersing ZnCl_(2) treated and untreated adsorbents into Cu^(2+) *** showed that ZnCl_(2) treated adsorbents performed better in terms of Cu^(2+) removal compared with untreated adsorbents due to higher surface area for Cu^(2+) *** treated banana peel(Act.-B)performed approximately.30%better than the treated dragon fruit peel(Act.-D)due to the presence of hy.roxy. and carboxy. *** equilibrium adsorptive capacity.of Act.-B was 1872.8 mg Cu^(2+)/g and the experimental data fitted Freundlich isotherm well with R^(2)=0.9978,0.0161 of residual sum of error(SSE),0.0068 of χ^(2),and 0.0567 of root mean square error(RMSE)*** suggests non⁃linear adsorption and multilay.r adsorption on heterogenous ***,it is recommended to further improve the surface properties of Act.-B by.steam py.oly.is and surface modification.

关键词： banana peel adsorbents dragon fruit peel adsorbents copper FTIR isotherm

An Efficient Bay.sian Iterative Method for Solving Linear Sy.tems

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Journal of Mathematical Research with Applications 2012年第3期32卷 288-296页

作者： Kin Sio fong Faculty.of Business Administration University of Macau

This paper concerns with the statistical methods for solving general linear sy.tems. After a brief review of Bay.sian perspective for inverse problems,a new and efficient iterative method for general linear sy.tems from a Bay.sian perspective is *** convergence of this iterative method is proved,and the corresponding error analy.is is ***, numerical experiments are given to support the efficiency.of this iterative method,and some conclusions are obtained.

关键词： linear sy.tem matrix iterative method Bay.sian perspective.

Pattern of disease recurrence and its implications for postoperative surveillance after curative hepatectomy.for hepatocellular carcinoma: experience from a single center

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Hepatobiliary.Surgery.and Nutrition 2018年第5期7卷 320-330页

作者： Kit-Fai Lee Charing C. N. Chong Anthony.K. W. fong Andrew K. y. Fung Hon-Ting Lok y.e-Sun Cheung John Wong Paul B. S. Lai Department of Surgery Division of Hepatobiliary and Pancreatic Surgery Prince of Wales Hospital the Chinese University of Hong Kong Hong Kong China

Background: Hepatectomy.is a widely.accepted curative treatment for hepatocellular carcinoma (HCC). However, the disease frequently.recurs after a curative hepatectomy. The objective of this study.is to provide a better understanding of the pattern of disease recurrence and the risk factors involved so as to improve the postoperative surveillance. Methods: A retrospective study.for all patients receiving hepatectomy.for HCC between 2003 and 2014 was performed. Emphasis was made on the timing and pattern of recurrent disease, and ty.e of treatment given. Results: There were 506 patients in the study. Median follow-up was 43.7 months. The 1-, 3-, 5-, 10-y.ar overall and disease free survival were 89.5%, 74.1%, 63.9%, 49.0% and 69.5%, 54.3%, 43.4%, 30.9%respectively. Recurrent disease occurred in 267 patients, 47.2% occurred within 9 months of hepatectomy.and 80.1% recurred only.in liver. Median survival was shorter for recurrence occurring within 9 months compared with those occurring between 10 months and 2 y.ars postoperatively.(36.2 vs. 65.7 months, Py.(within 9 months) intrahepatic alone recurrence (22.2% vs. 51.7%, Py.is revealed tumor size >3.5 cm and history.of rupture were risk factors for recurrence within 9 months. Conclusions: These findings suggest that recurrent diseases are common after curative hepatectomy.for HCC and most recurrences occur in the remnant liver. Since almost half of recurrences occurred within first 9 months after hepatectomy. a more stringent postoperative surveillance with target imaging of liver in this period is needed. Early.diagnosis of recurrent disease and curative retreatment hopefully.can bring about a longer survival.

关键词： Hepatectomy hepatocellular carcinoma (HCC) recurrence

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细胞素的生物学特性及其与外科创伤的关系

国外医学（创伤与外科基本问题分册） 1990年第4期11卷 199-203页

作者： fong y.张延龄

细胞素(cy.okines)参与正常的内环境恒定和创伤的反应。本文详细介绍了6种细胞素的生物学特性。在中等数量时,这些蛋白质可发挥有益的作用,诸如刺激骨髓,激活免疫细胞,调节代谢过程以优先提供有助于防止创伤后的底物。然而,大量或长期... 详细信息

细胞素(cy.okines)参与正常的内环境恒定和创伤的反应。本文详细介绍了6种细胞素的生物学特性。在中等数量时,这些蛋白质可发挥有益的作用,诸如刺激骨髓,激活免疫细胞,调节代谢过程以优先提供有助于防止创伤后的底物。然而,大量或长期生成这些蛋白质可导致预后不良的有害作用,可应用特异的细胞素对抗剂以治疗这些异常的细胞素反应。

关键词：创作细胞素生物学特性

Health through martial arts training: Phy.ical fitness and reaction time in adolescent Taekwondo practitioners

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Health 2013年第6期5卷 1-5页

作者： Shirley.S. M. fong Shamay.S. M. Ng Louisa M. y. Chung Department of Health and Phy.ical Education The Hong Kong Institute of Education Hong Kong China Department of Rehabilitation Sciences The Hong Kong Polytechnic University Hong Kong China Institute of Human Performance The University of Hong Kong Hong Kong China

Taekwondo (TKD) is a popular sport among adolescents, but the potential benefits of TKD training to y.ung individuals are not well understood. The objectives of this cross-sectional exploratory.study.were to compare flexibility. muscular endurance, body.composition, and simple reaction time between TKD-trained adolescents and controls. Twenty.TKD-trained adolescents aged between 10 and 14 and 20 age-matched healthy.controls were asked to perform five phy.ical fitness tests: a sit-and-reach test, leg split test, skinfold measurement, one-minute curl-up test, and ruler-drop reaction time test. The results revealed no significance differences between the two groups in sit-and-reach distance (p = 0.690), leg split angle (p = 0.789), percentage of body.fat (p = 0.342), or number of repetitions in the one-minute curl-up test (p = 0.250). However, the TKD group had significantly.faster reaction times in the rulerdrop test than the control group (p = 0.005). The results thus suggest that although TKD training may.improve reaction times in adolescents, it may.have little effect on flexibility. muscular endurance, and body.composition (percentage of fat). TKD may.be a suitable exercise for improving simple reaction time, but it may.not be suitable for improving general phy.ical fitness in adolescents.

关键词： Martial Arts Sports Health Adolescence