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Dermatofibrosarcoma Protuberans of the Breast: A Rare Localization

Advances in Breast Cancer Research 2024年第3期13卷 36-42页

作者： foba mamadou lassana Bathily Yaye Coumba Teuw El Hadj Daour Sankale Anne Aurore Fann Hospital Cheikh Anta Diop University Dakar Senegal Department of Gynecology and Obstetrics Grand Yoff Gnral Hospital Dakar Senegal Department of Plastic Surgery Fann Hospital Dakar Senegal

The dermatofibrosarcoma protuberans (DFP) is a rare skin tumor. It represents 0.1% of the malignant skin tumor. Surgery is its only treatment. The breast involvement is exceptional. We report our cases, 13 years old p... 详细信息

关键词： Breast Dermatofibrosarcoma Surgery

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Management of Phylloid Sarcomas: A Retrospective Study of 12 Cases

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Advances in Breast Cancer Research 2021年第2期10卷 25-33页

作者： Kanta Ka Abdoul Halim Bague Ibrahim Mounkeila mamadou lassana foba N. Zongo Davide Soldato Filippo Dall’Olio mamadou Moustapha Dieng Papa Macoumba Gaye Daniele Presti Radiotherapy Department Centre Hospitalier National Universitaire Dalal Jamm de Guédiawaye Guédiawaye Senegal School of Cancer Sciences Paris Sud Orsay French Unité D’oncologie Chirurgicale CHU Yalgado Ouedraogo Ouagadougou Burkina Faso Servie d’Oncologie Institut Joliot Curie Centre Hospitalier Universitaire Aristide Le Dantec Dakar Senegal Department of Plastic Surgery Aristide Le Dantec University Hospital Dakar Senegal University Cheikh Anta Diop of Dakar Dakar Senegal Medical Oncology Service ICS Maugeri IRCCS SpA University of Pavia Pavia Italy

Background: Phylloid sarcomas are rare. There is not enough data to codify the management. Objectives: The objective was to study the clinical and therapeutic aspects and the fate of patients after a follow-up of at least 4 years. Thus contributing to the limited body of knowledge on these tumors. Methods: a retrospective analysis of the files from 2013 to 2017 was carried out and patients were followed up until 2021at Hassan II Hospital. Epidemiological, clinical and therapeutic aspects were studied. Survival was calculated using the Kaplan-Meier method. Results: We collected 12 charts of patients treated for phyllodeal sarcoma from 2013 to 2017. The median age was 43 years. The circumstance of discovery was marked by the presence of nodule in all patients. The coupled echo-mammography examination classified the nodules, ACR 4 in 7 patients and ACR 3 in 3 and ACR 5 in 2 patients. Histological examination revealed a phylloid sarcoma in 11 patients and a borderline phylloid tumor in 1 patient. All patients had radical surgery with positive margins in 2 patients, 16.66%. One patient had revision surgery. Histological examination of the surgical specimens showed phylloid sarcoma on all specimens. All patients had adjuvant radiotherapy with doses of 50 Gy in 25 fractions of 2 Gy and a boost of 10 Gy was done in one patient. The median spread of radiotherapy was 37 days. Grade 1 and 2 skin toxicities were noted in 5 and 3 patients respectively. The median time from surgery to radiotherapy was 2.95 months. 3 patients relapsed after 13.6 months of follow-up. The recurrence-free survival at 1 and 3 years was 83% and

关键词： Phylloid Sarcoma Radiotherapy Survival

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