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Acute lobar nephritis in children: Not so easy to recognize and manage

World Journal of Clinical Pediatrics 2016年第1期5卷 136-142页

作者： Cristina Bibalo Andrea Apicella Veronica Guastalla Pierluigi Marzuillo floriana zennaro Carmela Tringali Andrea Taddio Claudio Germani Egidio Barbi Depart-ment of Pediatrics University of Trieste Department of Womenand Children and General and Specialized Surgery Seconda Università degli Studi di Napoli Institute for Maternal and Child Health - IRCCS "Burlo Garofolo" Pediatric Ward Ospedale di San Daniele San Daniele del Friuli

Acute lobar nephritis(ALN) is a localized non-liquefactive inflammatory renal bacterial infection, which typically involves one or more lobes. ALN is considered to be a midpoint in the spectrum of upper urinary tract infection, a spectrum ranging from uncomplicated pyelonephritis to intrarenal abscess. This condition may be difficult to recognize due to the lack of specific symptoms and laboratory findings. Therefore the disease is probably underdiagnosed. Computed tomography scanning represents the diagnostic gold standard for ALN, but magnetic resonance imagine could be considered in order to limit irradiation. The diagnosis is relevant since initial intravenous antibiotic therapy and overall length of treatment should not be shorter than 3 wk. We review the literature and analyze the ALN clinical presentation starting from four cases with the aim to give to the clinicians the elements to suspect and recognize the ALN in children.

关键词： Acute lobar nephritis Children Computed tomography Magnetic resonance imagine Upper urinary tract infection

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A LoRa-based protocol for connecting IoT edge computing nodes to provide small-data-based services

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Digital Communications and Networks 2022年第3期8卷 257-266页

作者： Kiyoshy Nakamura Pietro Manzoni Alessandro Redondi Edoardo Longo Marco zennaro Juan-Carlos Cano Carlos T.Calafate Universitat Politécnica de Valéncia ValenciaSpain Abdus Salam International Centre for Theoretical Physics(ICTP) TriesteItaly Politecnico di Milano MilanItaly

Data is becoming increasingly *** regularly interact with a variety of structured data,ranging from SQLite databases on the phone to personal sensors and open government ***“digital traces left by individuals through these interactions”are sometimes referred to as“small data”.Examples of“small data”include driving records,biometric measurements,search histories,weather forecasts and usage *** this paper,we present a flexible protocol called LoRaCTP,which is based on LoRa technology that allows data“chunks”to be transferred over large distances with very low energy *** provides all the mechanisms necessary to make LoRa transfer reliable by introducing a lightweight connection setup and allowing the ideal sending of an as-long-as necessary data *** designed this protocol as communication support for small-data edge-based IoT solutions,given its stability,low power usage,and the possibility to cover long *** evaluated our protocol using various data content sizes and communication distances to demonstrate its performance and reliability.

关键词： Small data Edge computing LoRa IoT

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高血压患者应用替米沙坦消除左室肥厚并改善舒张功能

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世界核心医学期刊文摘（心脏病学分册） 2005年第5期1卷 38-39页

作者： Mattioli A.V. zennaro M. Bonatti S. 宁宁 Department of Cardiology Univ. of Modena and Reggio Emilia Policlinico Via del Pozzo 71 41100 Modena Italy

Objectives: The study was designed to test whether or not the angiotensin II receptor blocker telmisartan brings about regression of left ventricular(LV) concentric hypertrophy and whether or not these changes are associated with improved diastolic filling. Methods: An echocardiographic follow-up study was performed in 85 hypertensive patients(systolic blood pressure[SBP] >140 mm Hg, diastolic blood pressure[DBP]->90 mm Hg) and mild-to-mod-erate LV hypertrophy(LV mass index related to body surface area[LVMI] 117-150 g/m2 for men and 105-150 g/m2 for women) treated with telmisartan monotherapy 40-80 mg once daily for 1 year. Blood pressure, LVMI, left atrial(LA) volumes, and diastolic function were determined at baseline and after 3, 6, 9, and 12 months of treatment. Blood pressure was also monitored at all visits. Diastolic function was assessed by examination of transmitral inflow and pulmonary vein flow patterns. Results: Telmisartan reduced blood pressure; after 12 months, the mean±S.D. SBP and DBP were reduced from 144±10 to 126±8mm Hg (p< 0.001) and from 98±8 to 86±7mm Hg(p< 0.001), respectively. The LVMI was decreased from 119±7 to 109±3g/m2 (p< 0.001) after 12 months’telmisartan treatment. All patients had diastolic dysfunction at baseline. After 12 months’telmisartan treatment, a normal pattern of transmitral inflow was present in 21%of patients. The regression of LV hypertrophy observed after 12 months was associated with increased peak early diastolic velocity/peak late diastolic velocity ratio from 0.60±0.18 to 0.83±0.20(p< 0.001), shortened isovolumic relaxation time(IVRT) from 110±13 to 105±13 ms(p< 0.001), and decreased deceleration time from 229±30 to 215±28 ms(p=0.002). Univariate analysis showed that shortened IVRT was related to a reduction in the LVMI and LA maximal and minimal volumes. In the multivariate analysis, the reduction in LVMI and the reduction in LA maximal and minimal volumes were independently associated with IVRT reduction. Conclusi

关键词：替米沙坦左室肥厚向心性肥厚质量指数左心室舒张功能障碍等容舒张期静脉血流左心房体表面积

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年轻患者的急性心肌梗死:营养状态和生化因子

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世界核心医学期刊文摘（心脏病学分册） 2005年第10期1卷 49-50页

作者： Mattioli A. V. Bonetti L. zennaro M. 郭战宏 Department of Cardiology Univ. of Modena and Reggio Emilia Via del pozzo 71 41100 Modena Italy

The aim of this study was to establish whether nutritional status and biochemical factors, C-reactive protein(CRP), serum amyloid A(SAA) protein, serum iron(Fe) and fibrinogen at admission were different in patients with acute myocardial infarction(AMI) at a young age(60 years). We also investigated whether during the stay in the hospital, the increase in acute-phase reactants was different in young vs. older subjects, and if dyslipidemic aspects were different between the two groups. Methods: The study population consisted of 40 patients, all males with a mean age of 36.7± 1.16 years, admitted to our facility with AMI. The control group included 40 patients, all males, mean age of 66.3± 4.24 years, with AMI. CRP, SAA, Fe and fibrinogen were determined at admission to the hospital and daily for 7 days in the two groups of patients. Results: In young patients the median value of the highest levels were 6.2 mg/l(range 0.7- 27.30) for CRP, 13.22 mg/l(range 0.7- 130) for SAA, 420 mg/dl(range 76- 840) for fibrinogen and 49.1 gamma/ml(range 14- 102) for Fe levels. In the older patients, the median value of the highest levels were 5.9 mg/l(range 0.6- 28.30) for CRP, 12.12 mg/l(range 0.9- 280) for SAA, 480 mg/dl(range 60- 780)- for fibrinogen and 47.1 gamma/ml(range 12- 94) for Fe levels. Conclusions: In the present study, acute-phase reactants were quantitatively similar in young and old patients. On the contrary, nutritional status, homocysteine, LDL and triglycerides are significantly higher in young patients than in old patients.

关键词：急性心肌梗死生化因子营养状态急性期反应物血清铁血脂异常淀粉样中位值

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小儿造血干细胞移植受体MR对比增强后肝脏钆沉积与消除

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国际医学放射学杂志 2017年第1期 82-83页

作者： N.Maximova M.Gregori F.zennaro A.Sonzogni R.Simeone D.Zanon 赵玉娇 Bone Marrow Transplant Unit Institute for Maternal and Child Health-IRCCS Burlo Garofolo

摘要目的探讨在行钆剂对比增强MR检查后,肝脏钆沉积是否只发生在铁过载而肝肾功能正常的小儿病人中。材料与方法本研究设计和执行已通过女性和儿童健康研

关键词：对比增强病人铁过载 MR 肝脏

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